2.3.1.240: narbonolide synthase
This is an abbreviated version!
For detailed information about narbonolide synthase, go to the full flat file.
Reaction
+
6 (2S)-methylmalonyl-CoA
+
5 NADPH
+
5 H+
=
+
7 CoA
+
7 CO2
+
5 NADP+
+
2 H2O
Synonyms
methymycin/picromycin polyketide synthase, picromycin/methymycin PKS, picromycin/methymycin polyketide synthase, PICS, PikAI, PikAIII, PikAIV, pikromycin PKS, pikromycin polyketide synthase, type I polyketide synthase PikAIV
ECTree
Natural Substrates Products
Natural Substrates Products on EC 2.3.1.240 - narbonolide synthase
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malonyl-CoA + 6 (2S)-methylmalonyl-CoA + 5 NADPH + 5 H+
narbonolide + 7 CoA + 7 CO2 + 5 NADP+ + 2 H2O
the product narbonolide is an intermediate in the biosynthesis of methymycin
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