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2.3.1.251: lipid IVA palmitoyltransferase

This is an abbreviated version!
For detailed information about lipid IVA palmitoyltransferase, go to the full flat file.

Word Map on EC 2.3.1.251

Reaction

1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine
+
hexa-acyl lipid A
=
2-acyl-sn-glycero-3-phosphocholine
+
hepta-acyl lipid A

Synonyms

crcA, lipid A palmitoyltransferase, PA1343, PagP

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.251 lipid IVA palmitoyltransferase

Systematic Name

Systematic Name on EC 2.3.1.251 - lipid IVA palmitoyltransferase

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SYSTEMATIC NAME
IUBMB Comments
1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine:lipid-IVA palmitoyltransferase
Isolated from the bacteria Escherichia coli and Salmonella typhimurium. The enzyme prefers phosphatidylcholine with a palmitoyl group at the sn-1 position and palmitoyl or stearoyl groups at the sn-2 position. There is some activity with corresponding phosphatidylserines but only weak activity with other diacylphosphatidyl compounds. The enzyme also acts on Kdo-(2->4)-Kdo-(2->6)-lipid IVA.