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2.4.1.144: beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase

This is an abbreviated version!
For detailed information about beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase, go to the full flat file.

Word Map on EC 2.4.1.144

Reaction

UDP-N-acetyl-alpha-D-glucosamine
+
beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein]
=
UDP
+
beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-[beta-D-GlcNAc-(1->4)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein]

Synonyms

(GnT)-III, acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-glycopeptide beta4-, III, beta(1,4)-N-acetylglucosaminyltransferase III, beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, beta-1,4-N-acetylglucosaminyltransferase III, beta-D-mannoside beta-1,4-N-acetylglucosaminyltransferase, beta1,4-N-acetylglucosaminyltransferase III, EC 2.4.1.51, GlcNAc-transferase-III, GlcNAcTase-III, GnT-III, GnTIII, Golgi beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase III, MGAT3, N-acetyl-glucosaminyltransferase III, N-acetylglucosaminyltransferase III, N-acetylglucosaminyltransferase-III, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III, uridine diphosphate (UDP)-N-acetylglucosamin/beta-D-mannoside beta-1,4-N-acetylglucosaminyltransferase III, uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase III

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.144 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase

Specific Activity

Specific Activity on EC 2.4.1.144 - beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.000000022
-
hepatoma cells
0.0000001
-
HB611 cells
0.00000013
-
normal liver
0.0000004
-
HB611 cells treated with interferon-alpha-2a
0.0000009
recombinant enzyme in HeLa cells
0.0000021
-
Huh6 cells treated with interferon-alpha-2a
0.0000023
-
Huh6 cells
0.0000025
-
hepatoma cell line 7721
0.000004
-
about, hepatoma cell line 7721, all-trans retinoic acid treated
0.0000096
-
fetal primary hepatocytes
0.000012
-
purified enzyme
0.0000124
-
hepatic carcinoma cells
0.000017
-
wild-type and mutant D329A
0.000018
-
HepG2 cells
0.000024
-
Hep3B cells
0.00006
recombinant enzyme in COS-1 cells
0.000083
-
-
0.02
-
purified recombinant enzyme
5.52
purified enzyme
additional information