2.4.1.237: flavonol 7-O-beta-glucosyltransferase
This is an abbreviated version!
For detailed information about flavonol 7-O-beta-glucosyltransferase, go to the full flat file.
Word Map on EC 2.4.1.237
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2.4.1.237
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thiolactomycin
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flavonols
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glucosylation
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beta-ketoacyl-acp
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mycolic
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petals
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condensing
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flavanones
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coumarins
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7-hydroxyl
- 2.4.1.237
- thiolactomycin
- flavonols
-
glucosylation
-
beta-ketoacyl-acp
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mycolic
- petals
-
condensing
- flavanones
- coumarins
-
7-hydroxyl
Reaction
Synonyms
F 7 GT, F7GT, flavonol 7-O-glucosyltransferase, GT2, NTGT2, Q7OGT, quercetin 7OGT, quercetin-7-O-GT, UDP-glucose:flavonoid 7-O-glucosyltransferase, UDP-glucose:flavonol 7-O-glucosyltransferase, UDPG:flavonol 7-O-glucosyltransferase, UGT71F1, UGT73A4
ECTree
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Inhibitors
Inhibitors on EC 2.4.1.237 - flavonol 7-O-beta-glucosyltransferase
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4,4'-diisothiocyanostilbene-2,2'-disulfonic acid
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0.01 mM, UGT71F1; 0.01 mM, UGT73A4
diethyldicarbonate
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5 mM, 98% inhibition with quercetin or gossypetin as substrate
p-chloromercuribenzene sulfonic acid
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UGT71F1, 0.01mM, 22% inhibition; UGT73A4 activity is completely inhibited at 0.01mM
p-hydroxymercuribenzoate
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strong, 0.1 mM, 99.3% inhibition with quercetin as substrate, 14 mM 2-mercaptoethanol protects and addition after 15 min also reduces the inhibitory effect
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complete inhibition near 0.04 mM, UGT71F1; complete inhibition near 0.04 mM, UGT73A4
Co2+
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1 mM, 98% inhibition with quercetin as substrate, 85% inhibition with gossypetin as substrate
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complete inhibition near 0.04 mM, UGT71F1; complete inhibition near 0.04 mM, UGT73A4
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1 mM, 97% inhibition, 14 mM 2-mercaptoethanol partially restores activity
N-ethylmaleimide
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strong, 1 mM, 98% inhibition with quercetin as substrate, 14 mM 2-mercaptoethanol protects, but addition after 15 min does not restore activity
N-ethylmaleimide
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1 mM, 94% inhibition, 14 mM 2-mercaptoethanol restores activity
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1 mM, 97% inhibition, 14 mM 2-mercaptoethanol partially restores activity
p-chloromercuribenzoate
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1 mM, 91% inhibition, 14 mM 2-mercaptoethanol restores activity