2.4.1.301: 2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase
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For detailed information about 2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase, go to the full flat file.
Reaction
Synonyms
KanE, KanM2
ECTree
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Cloned
Cloned on EC 2.4.1.301 - 2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase
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expression in Streptomyces venezuelae. Reconstructed the kanamycin pathway stepwise in a mutant strain of Streptomyces venezuelae lacking the genes for biosynthesis of the native deoxysugar by transplanting plasmids harboring different combinations of putative genes from Streptomyces kanamyceticus in Streptomyces venezuelae and then carrying out biochemical analysis and chemical characterization