2.4.2.26: protein xylosyltransferase
This is an abbreviated version!
For detailed information about protein xylosyltransferase, go to the full flat file.
Word Map on EC 2.4.2.26
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2.4.2.26
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proteoglycans
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glycosaminoglycans
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chondroitin
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heparan
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xylosylation
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chain-initiating
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xylts
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medicine
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bikunin
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laxity
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desbuquois
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elasticum
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pseudoxanthoma
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diagnostics
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analysis
- 2.4.2.26
- proteoglycans
- glycosaminoglycans
- chondroitin
- heparan
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xylosylation
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chain-initiating
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xylts
- medicine
- bikunin
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laxity
-
desbuquois
- elasticum
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pseudoxanthoma
- diagnostics
- analysis
Reaction
Synonyms
LARGE, More, peptide O-xylosyltransferase, peptide O-xylosyltransferase 1, peptide-O-xylosyltransferase, Rumi, squashed vulva protein 6, SQV-6, UDP-alpha-D-xyloase:proteoglycan core protein beta-D-xylosyltransferase, UDP-alpha-D-xylose:proteoglycan core protein beta-D-xylosyltransferase, UDP-D-xylose:core protein beta-D-xylosyltransferase, UDP-D-xylose:core protein xylosyltransferase, UDP-D-xylose:proteoglycan core protein b-d-xylosyltransferase, UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase, UDP-xylose-core protein beta-D-xylosyltransferase, uridine diphosphoxylose-core protein beta-xylosyltransferase, uridine diphosphoxylose-protein xylosyltransferase, XT, XT-I, XT-II, xylosyltransferase, xylosyltransferase 1, xylosyltransferase 2, xylosyltransferase I, xylosyltransferase II, xylosyltransferase sqv-6, xylosyltransferase, uridine diphosphoxylose-core protein beta-, xylosyltransferase-I, xylosyltransferases II, XylT-I, XylT-II, XYLT1, XYLT2
ECTree
2.4.2.26 protein xylosyltransferaseAdvanced search results
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results (Source Tissue
Source Tissue on EC 2.4.2.26 - protein xylosyltransferase
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SOURCE TISSUE 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
SOURCE
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XT-II mRNA expression is higher than for XT-I. Very low XT-I mRNA expression
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unactivated platelets harbor significant XylT activity that is released upon activation with thrombin
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XT-II mRNA expression is higher than for XT-I. Very low XT-I mRNA expression
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XT-II mRNA expression is higher than for XT-I. Very low XT-I mRNA expression
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XT-II mRNA expression is higher than for XT-I. Very low XT-I mRNA expression
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XT-II mRNA expression is higher than for XT-I. Very low XT-I mRNA expression
mesenchymal stem cell. Xylosyltransferase 1 is the predominant xylosyltransferase in the early phase of chondrogenic stem cell differentiation and xylosyltransferase 2 is upregulated 7 days after induction
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XT-II mRNA expression is higher than for XT-I. Very low XT-I mRNA expression
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of healthy and infertile men with oligo-, astheno- or teratozoospermia, and of men after vasectomy
additional information
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XylT levels in plasma are approximately 200% lower than those in serum due in part to XylT released by platelets during blood clotting in vitro. In Xylt2+/+ mice, total serum XylT activity is 42% higher than in plasma. In Xylt2-/- mice, no significant difference between serum and plasma total XylT activity
elevated xylosyltransferase I activities in Pseudoxanthoma elasticum patients
increased activity of xylosyltransferase I in the blood serum of patients with connective tissue diseases
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XylT2 is predominant. XylT levels in serum are approximately 200% higher than those in plasma due in part to XylT released by platelets during blood clotting in vitro. In Xylt2+/+ mice, total serum XylT activity is 42% higher than in plasma. In Xylt2-/- mice, no significant difference between serum and plasma total XylT activity
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of JAR choriocarcinoma cells secrete six times more XT-I than the osteogenic sarcoma cell line SAOS-2 and 40times more XT-I than the fibroblast cell line hTERT-BJ1
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XT-II mRNA expression is higher than for XT-I. Low XT-I mRNA expression
expresson of xylosyltransferase 2, no expression of xylosyltransferase 1
XT-II is exclusively expressed in liver tissues, in the HeLa cervical carcinoma cell line, and in K-562 erythroleukemia cells
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XT-II mRNA expression is higher than for XT-I. Very low XT-I mRNA expression
expresson of xylosyltransferase 2, no expression of xylosyltransferase 1
expresson of xylosyltransferase 2, no expression of xylosyltransferase 1
XT-II is exclusively expressed in liver tissues, in the HeLa cervical carcinoma cell line, and in K-562 erythroleukemia cells
XT-II is highly expressed in liver, no XT-I mRNA is detectable in liver
mesenchymal stem cell. Xylosyltransferase 1 is the predominant xylosyltransferase in the early phase of chondrogenic stem cell differentiation and xylosyltransferase 2 is upregulated 7 days after induction
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of healthy and infertile men with oligo-, astheno- or teratozoospermia, and of men after vasectomy
additional information
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no activity in liver and intestine with an exogenous receptor
additional information
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activity in several human cell lines, culture supernatant, overview
additional information
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enzyme activity in seminal plasma of infertile men is significantly reduced
additional information
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equal expression levels of XT-I and XT-II in 1301 cells, WERI-RB-1 cells and HS-27 cells. In 3051/80 cells, SW-982 cells, MHH-ES-1 cells, hTERT-BJ1 cells and EFO-21 cells, XT-II mRNA expression is higher than for XT-I. In 23132/87 cells, XT-I mRNA expression is higher than for XT-II. In NCI-H510A cells, highest XT-I expression levels, XT-I mRNA expression is higher than for XT-II
