2.4.99.20: 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase
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For detailed information about 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, go to the full flat file.
Reaction
Synonyms
2'-phospho-cyclic-ADP-ribose transferase, ADP-ribosyl cyclase 1, ADPRC 1, BST1, CD38, diphosphopyridine nucleosidase
ECTree
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Crystallization
Crystallization on EC 2.4.99.20 - 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase
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complex of isoform CD38 with substrate NMN shows that the nicotinamide moiety is in close contact with Glu146 at 3.27 A and Asp155 at 2.52 A. Residue Asp147 is situated and directed away from the bound substrate