2.5.1.20: rubber cis-polyprenylcistransferase
This is an abbreviated version!
For detailed information about rubber cis-polyprenylcistransferase, go to the full flat file.
Word Map on EC 2.5.1.20
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2.5.1.20
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dolichols
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brasiliensis
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hevea
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allylic
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undecaprenyl
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parthenium
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argentatum
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polyprenols
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isoprene
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prenyltransferases
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guayule
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polyisoprenoids
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cis-1,4-polyisoprene
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trans-prenyltransferases
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ficus
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dimethylallyl
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rubber-producing
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nogo-b
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elastica
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neryl
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dehydrodolichyl
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dhdds
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cis-polyisoprene
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molecular biology
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synthesis
- 2.5.1.20
- dolichols
- brasiliensis
- hevea
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allylic
- undecaprenyl
- parthenium
- argentatum
- polyprenols
- isoprene
- prenyltransferases
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guayule
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polyisoprenoids
- cis-1,4-polyisoprene
- trans-prenyltransferases
- ficus
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dimethylallyl
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rubber-producing
- nogo-b
- elastica
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neryl
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dehydrodolichyl
- dhdds
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cis-polyisoprene
- molecular biology
- synthesis
Reaction
Synonyms
allyltransferase, rubber, chain-elongating enzyme cis-prenyltransferase, cis prenyl transferase, cis-1,4-polyprenylcistransferase, cis-prenyl transferase, cis-prenyltransferase, cisprenyltransferase, CPT, CPT3, CPT6, HRT1, HRT2, isopentenyl pyrophosphate cis-1,4-polyisoprenyl transferase, laticifer-specific rubber-forming enzyme, More, RT-ase complex, rTase, rubber allyltransferase, rubber polymerase, rubber prenyltransferase, rubber transferase, rubber transferase 1, rubber transferase 2, rubber transferase complex, RubCPT1, TkCPT1, TkCPT2, TkCPT3, TkCPTL1
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General Information
General Information on EC 2.5.1.20 - rubber cis-polyprenylcistransferase
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evolution
a detailed sequence structure analysis of the most prominent variant, RubCPT1 from five genotypes reveales that despite their common Wickham base origin, there exists abundant genetic diversity in this important rubber biosynthesis gene among them. The abundance of non-synonymous SNPs and their inheritance pattern indicate that most of the SNP substitutions are not of recent origin but is the result of naturally occurred recombination events present in the seeds even before they are collected by Sir Hendry Wickham from the Amazon base
malfunction
metabolism
physiological function
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CPT-RNAi plants indicate a significant reduction in rubber biosynthesis and a corresponding 50% increase in the levels of triterpenes and inulin, the primary storage carbohydrate compared to wild-type plants. The laticifers in CPT-RNAi plants contained fewer and smaller rubber particles than wild-type laticifers. And a decrease is noted in the activity of hydroxymethylglutaryl-CoA reductase, a key enzyme in the mevalonate pathway, reflecting homeostatic control of the isopentenyl diphosphate pool, CPT RNAi silencing phenotypes, overview
malfunction
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knockdown of the gene for subunit TkCPTL1 leads to abolished poly(cis-1,4-isoprene) synthesis
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enzyme produces very pure poly(cis-1,4-isoprene) and retains its capacity to produce natural rubber ex vivo
metabolism
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HRT2 is thought to be a key enzyme in the biosynthesis of natural rubber
metabolism
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the isoprenoid pathway includes the enzymes that can also compete with rubber transferase for isopentenyl pyrophosphate (monomer), allylic pyrophosphate (initiator), and magnesium ions (activator), overview
metabolism
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the isoprenoid pathway includes the enzymes that can also compete with rubber transferase for isopentenyl pyrophosphate (monomer), allylic pyrophosphate (initiator), and magnesium ions (activator), overview
metabolism
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the isoprenoid pathway includes the enzymes that can also compete with rubber transferase for isopentenyl pyrophosphate (monomer), allylic pyrophosphate (initiator), and magnesium ions (activator), overview
metabolism
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the isoprenoid pathway includes the enzymes that can also compete with rubber transferase for isopentenyl pyrophosphate (monomer), allylic pyrophosphate (initiator), and magnesium ions (activator), overview
metabolism
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the isoprenoid pathway includes the enzymes that can also compete with rubber transferase for isopentenyl pyrophosphate (monomer), allylic pyrophosphate (initiator), and magnesium ions (activator), overview
metabolism
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the isoprenoid pathway includes the enzymes that can also compete with rubber transferase for isopentenyl pyrophosphate (monomer), allylic pyrophosphate (initiator), and magnesium ions (activator), overview
metabolism
the enzyme is involved in the biosynthesis of natural rubber. It exhibits distinct rubber transferase activity in vitro only when it is introduced on detergent washed Hevea rubber particles by a cell-free translation-coupled system
metabolism
the enzyme responsible for the synthesis of long polyisoprene chains. It is involved in biosynthesis of natural rubber
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the species produce large amounts of high-quality natural rubber in its latex. This high-molecular mass biopolymer consists mainly of poly(cis-1,4-isoprene) and is deposited in rubber particles by particle-bound enzymes that carry out the condensation of isopentenyl diphosphate units. Large polymer formation is carried out by the chain-elongating enzyme cis-prenyltransferase, CPT
physiological function
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the species produce large amounts of high-quality natural rubber in its latex. This high-molecular mass biopolymer consists mainly of poly(cis-1,4-isoprene) and is deposited in rubber particles by particle-bound enzymes that carry out the condensation of isopentenyl diphosphate units. Large polymer formation is carried out by the chain-elongating enzyme cis-prenyltransferase, CPT