2.5.1.41: phosphoglycerol geranylgeranyltransferase

This is an abbreviated version!
For detailed information about phosphoglycerol geranylgeranyltransferase, go to the full flat file.

Reaction

Synonyms

((S)-GGGP) synthase, (S)-3-O-geranylgeranylglyceryl phosphate synthase, (S)-3-O-geranylgeranylglycerylphosphate, geranylgeranyl diphosphate:sn-3-O-(geranylgeranyl)glycerol 1-phosphate geranylgeranyltransferase, geranylgeranyl-transferase, geranylgeranylglycerol-phosphate geranylgeranyltransferase, geranylgeranylglyceryl phosphate synthase, geranylgeranyltransferase II, geranylgeranyltransferase, geranylgeranyloxyglycerol phosphate, GGGP synthase, GGGPS, glycerol phosphate feranylgeranyltransferase, prenyltransferase

ECTree

     2 Transferases

         2.5 Transferring alkyl or aryl groups, other than methyl groups

             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

                2.5.1.41 phosphoglycerol geranylgeranyltransferase

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Results	in table
1	Activating Compound
4456	AA Sequence
1	CAS Registry Number
6	Cloned(Commentary)
3	Crystallization (Commentary)
5	General Information
1	Inhibitors
4	KM Value [mM]
2	Localization
2	Metals/Ions
3	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
41	Organism
5	Pathway
26	PDB ID
2	pH Optimum
1	pH Range
4	Purification (Commentary)
1	Reaction
1	Reaction Type
12	Reference
2	Source Tissue
12	Substrates and Products (Substrate)
6	Subunits
26	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]

General Information

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General Information on EC 2.5.1.41 - phosphoglycerol geranylgeranyltransferase

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GENERAL INFORMATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

evolution

Thaumarchaeota

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diversity of thaumarchaeotal GGGP synthases in the marine water column, phylogenetic analysis and tree and correlation to the classification of shallow and deep water clusters, overview. Differences in isoprenoid glycerol dialkyl glycerol tetraethers distributions from subsurface to deep waters that may be explained by differences in the GGGP synthase, suggesting a genetic control on isoprenoid glycerol dialkyl glycerol tetraethers distribution. Diversity of archaeal GGGP synthases, overview

738116

metabolism

3 entries

physiological function

Thaumarchaeota

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the key enzyme catalyses the formation of an ether bond between isoprenyl diphosphate and glycerol-1-phosphate to form 3-(O-geranylgeranyl)-sn-glycerol 1-phosphate, and is the first committed step towards ether membrane lipid synthesis

738116

metabolism

Thaumarchaeota

-

key enzyme of the thaumarchaeotal lipid biosynthetic pathway

738116

metabolism

Thermoplasma volcanium

Q97AR4

first committed step in the biosynthetic pathway of glycerol dibiphytanyl glycerol tetraethers, the membrane lipids of the thermophilic and acidophilic euryarchaeota

758592

metabolism

Thermoplasma volcanium ATCC 51530

-

first committed step in the biosynthetic pathway of glycerol dibiphytanyl glycerol tetraethers, the membrane lipids of the thermophilic and acidophilic euryarchaeota

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