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2.6.1.71: lysine-pyruvate 6-transaminase

This is an abbreviated version!
For detailed information about lysine-pyruvate 6-transaminase, go to the full flat file.

Reaction

L-lysine
+
pyruvate
=
(S)-2-amino-6-oxohexanoate
 +
L-alanine

Synonyms

lys-AT, lysine-pyruvate aminotransferase

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.71 lysine-pyruvate 6-transaminase

Inhibitors

Inhibitors on EC 2.6.1.71 - lysine-pyruvate 6-transaminase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
CaCl2
-
80% remaining activity at 1 mM, 7% remaining activity at 10 mM
CoCl2
-
9% activity retained at 1 mM, complete inhibition at 10 mM
CuCl2
-
complete inhibition at 1 mM or higher
EDTA
-
89% activity retained at 1 mM, 36% activity retained at 10 mM
FeCl2
-
23% activity retained at 1 mM, 13% activity retained at 10 mM
HgCl2
-
40% activity retained at 1 mM, 31% activity retained at 10 mM
hydroxylamine
-
37% activity retained at 1 mM, 6% activity retained at 10 mM
MgCl2
-
98% activity retained at 1 mM, 22% activity retained at 10 mM
MnCl2
-
57% activity retained at 1 mM, 3% activity retained at 10 mM
p-chloromercuribenzoate
-
5% activity retained at 1 mM, 1% activity retained at 10 mM
SnCl2
-
97% activity retained at 1 mM, 40% retained activity at 10 mM
additional information
-
KF, KCN, sodium azide, Na2HAsSO4, NaHSO4, 2-mercaptoethanol, dithioerythritol, reduced glutathione, proteinogenic amino acids, none of them has inhibitory effects even at 10 mM
-