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2.7.1.19: phosphoribulokinase

This is an abbreviated version!
For detailed information about phosphoribulokinase, go to the full flat file.

Word Map on EC 2.7.1.19

Reaction

ATP
+
D-ribulose 5-phosphate
=
ADP
 +
D-ribulose 1,5-bisphosphate

Synonyms

5-phosphoribulose kinase, AT1G32060, AtPRK, CrPRK, glyceraldehyde-3-phosphate dehydrogenase/CP12/phosphoribulokinase, kinase, phosphoribulo- (phosphorylating), Mext_0980, phosphopentokinase, phosphoribulokinase, PKK, Prk, PrkA, PRuK, ribulose 5-phosphate kinase, ribulose phosphate kinase, ribulose-5-phosphate kinase, SePRK, synpcc7942_0977

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.19 phosphoribulokinase

Inhibitors

Inhibitors on EC 2.7.1.19 - phosphoribulokinase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3-phosphoglycerate
-
74% inhibition at 6 mM and pH 7.2
5,5'-dithiobis(2-nitrobenzoic acid)
DTNB, Ellman’s reagent, almost complete inhibition at 0.0045 mM
6-phospho-D-gluconate
6-phosphogluconate
-
competitive inhibitor, 78% residual activity at 1 mM
chloroplast protein 12
-
cystine
-
oxidized form, inhibition almost completely reversible by addition of reduced dithiothreitol
D-Ribulose 1,5-diphosphate
daphnetin
-
i.e. 7,8-dihydroxycoumarin
diethyl dicarbonate
-
27% residual activity at 0.04 mM
dithiobis-(2-nitrobenzoic acid)
-
complete inactivation, 3 mM ATP protects
dithiothreitol
DL-glyceraldehyde
-
non competitive, 10 mM
glutathione
H2O2
-
complete inactivation, 3 mM ATP protects
iodoacetate
-
-
L-aspartate
-
competitive, 1 mM
L-malate
-
competitive, 1 mM
p-chloromercuribenzoate
-
-
phosphoenolpyruvate
pyridoxal 5'-phosphate
regulatory protein CP12
-
forming under oxidizing conditions a supramolecular complex (2 phosphoribulokinase dimers + 2 glyceraldehyde-3-phosphate dehydrogenase tetramers + 4 CP12 monomers)
-
additional information
-