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2.7.7.41: phosphatidate cytidylyltransferase

This is an abbreviated version!
For detailed information about phosphatidate cytidylyltransferase, go to the full flat file.

Word Map on EC 2.7.7.41

Reaction

CTP
+
phosphatidate
=
diphosphate
+
CDP-diacylglycerol

Synonyms

CarS, CDP diacylglycerol synthase, CDP-DAG synthase, CDP-DG, CDP-DG synthase, CDP-DG synthetase, CDP-diacylglyceride synthetase, CDP-diacylglycerol synthase, CDP-diacylglycerol synthetase, CDP-diglyceride pyrophosphorylase, CDP-diglyceride synthetase, CDPdiglyceride pyrophosphorylase, CDS, CDS1, CDS2, CDS3, Cds4, Cds5, CdsA, CTP-diacylglycerol synthetase, CTP:1,2-diacylglycerophosphate-cytidyl transferase, CTP:phosphatidate cytidylyltransferase, cytidine 5'-diphosphate diacylglycerol synthase, cytidine diphosphoglyceride pyrophosphorylase, cytidinediphosphate diacylglycerol synthase, cytidylyltransferase, phosphatidate, DAG synthetase, More, phosphatidate cytidyltransferase, phosphatidate cytidyltransferase 2, phosphatidic acid cytidylyltransferase, SJAG_00426, Tam41, TAMM41, Tb927.7.220, TbCDS, YnbD

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.7 Nucleotidyltransferases
                2.7.7.41 phosphatidate cytidylyltransferase

Disease

Disease on EC 2.7.7.41 - phosphatidate cytidylyltransferase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Carcinoma, Hepatocellular
Altered subcellular and submitochondrial localization of CTP:phosphatidate cytidylyltransferase in the Morris 7777 hepatoma.
Methylation Inactivates Expression of CDP-diacylglycerol Synthase 1 (CDS1) in Hepatocellular Carcinoma.
Phosphatidylserine biosynthesis in mitochondria from the Morris 7777 hepatoma.
Eye Diseases
Isolation and chromosomal localization of two human CDP-diacylglycerol synthase (CDS) genes.
Heart Defects, Congenital
TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy.
Infertility, Male
Reduced expression of CDP-DAG synthase changes lipid composition and leads to male sterility in Drosophila.
Retinal Degeneration
Isolation and characterization of murine Cds (CDP-diacylglycerol synthase) 1 and 2.
Isolation and chromosomal localization of two human CDP-diacylglycerol synthase (CDS) genes.
Starvation
Regulation of CDP-diacylglycerol synthesis and utilization by inositol and choline in Schizosaccharomyces pombe.