1.14.11.B11: L-asparagine hydroxylase

This is an abbreviated version!
For detailed information about L-asparagine hydroxylase, go to the full flat file.

Reaction

L-asparagine
+
2-oxoglutarate
+
O2
=
(2S,3S)-3-hydroxyasparagine
+
succinate
+
CO2

Synonyms

AsnO, asparagine hydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.B11 L-asparagine hydroxylase

Engineering

Engineering on EC 1.14.11.B11 - L-asparagine hydroxylase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
D241N
-
the mutant shows low activity compared to the wild type enzyme
D246N
-
the mutant shows low activity compared to the wild type enzyme
D241N
-
the mutant shows low activity compared to the wild type enzyme
-
D246N
-
the mutant shows low activity compared to the wild type enzyme
-