1.14.13.158: amorpha-4,11-diene 12-monooxygenase

This is an abbreviated version, for detailed information about amorpha-4,11-diene 12-monooxygenase, go to the full flat file.

Reaction

amorpha-4,11-diene
+ 3 O2 + 3 NADPH + 3 H+ =
artemisinate
+ 3 NADP+ + 4 H2O

Synonyms

ALDH1, amorpha-4,11-diene C-12 oxidase, CYP71AV1, cytochrome P450 monooxygenase 71 AV1

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.158 amorpha-4,11-diene 12-monooxygenase

Substrates Products

Substrates Products on EC 1.14.13.158 - amorpha-4,11-diene 12-monooxygenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-nonenal + O2 + NADPH + H+
? + NADP+ + 2 H2O
show the reaction diagram
-
-
-
-
amorpha-4,11-diene + O2 + NADPH + H+
artemisinic alcohol + NADP+ + H2O
show the reaction diagram
artemisinic alcohol + O2 + NADPH + H+
artemisinic aldehyde + NADP+ + 2 H2O
show the reaction diagram
artemisinic aldehyde + O2 + NADPH + H+
artemisinate + NADP+ + H2O
show the reaction diagram
dihydroartemisinic alcohol + O2 + NADPH + H+
dihydroartemisinic aldehyde + NADP+ + 2 H2O
show the reaction diagram
dihydroartemisinic aldehyde + O2 + NADPH + H+
dihydroartemisinate + NADP+ + H2O
show the reaction diagram
-
-
-
-
octanal + O2 + NADPH + H+
? + NADP+ + 2 H2O
show the reaction diagram
-
-
-
-
additional information
?
-