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EC 3.8.1.7 Details
EC number
3.8.1.7
Accepted name
4-chlorobenzoyl-CoA dehalogenase
Reaction
4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl CoA + chloride
Systematic name
4-chlorobenzoyl CoA chlorohydrolase
CAS registry number
141583-18-8
Comment
Specific for dehalogenation at the 4-position. Can dehalogenate substrates bearing fluorine, chlorine, bromine and iodine in the 4-position. This enzyme is part of the bacterial 2,4-dichlorobenzoate degradation pathway.
History
created 1999