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Information on EC 1.1.1.360 - glucose/galactose 1-dehydrogenase

for references in articles please use BRENDA:EC1.1.1.360

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IUBMB Comments

A zinc protein. The enzyme from the archaeon Picrophilus torridus is involved in glucose and galactose catabolism via the nonphosphorylative variant of the Entner-Doudoroff pathway. It shows 20-fold higher activity with NADP+ compared tor NAD+. The oxidation of D-glucose and D-galactose is catalysed at a comparable rate (cf. EC 1.1.1.119, glucose 1-dehydrogenase (NADP+) and EC 1.1.1.120, galactose 1-dehydrogenase (NADP+)).

The enzyme appears in viruses and cellular organisms

Synonyms
dual-specific glucose/galactose dehydrogenase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
D-galactopyranose + NADP+ = D-galactono-1,5-lactone + NADPH + H+
show the reaction diagram
D-glucopyranose + NADP+ = D-glucono-1,5-lactone + NADPH + H+
show the reaction diagram
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