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EC Tree
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
nadph peroxidase,
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NADHP2 peroxidase
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nicotinamide adenine dinucleotide phosphate peroxidase
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triphosphopyridine nucleotide peroxidase
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NADPH peroxidase
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NADPH + H+ + H2O2 = NADP+ + 2 H2O
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oxidation
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redox reaction
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reduction
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NADPH:hydrogen-peroxide oxidoreductase
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NADH + H2O2
NAD+ + H2O
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25% of the rate with NADPH
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NADPH + H+ + H2O2
NADP+ + 2 H2O
NADPH + H+ + H2O2
NADP+ + 2 H2O
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NADPH + H+ + H2O2
NADP+ + 2 H2O
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NADPH + H2O2
NADP+ + H2O
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NADPH + H2O2
NADP+ + H2O
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O2
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aerobic conditions required for reaction
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35.3
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cells in exponential phase growth
39.6
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cells in stationary phase growth
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B-1388 strain
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brenda
B-1388 strain
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brenda
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brenda
strains ZAS-1 and ZAS-2
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brenda
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brenda
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brenda
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brenda
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30% of the total activity
brenda
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30% of the total activity
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brenda
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70% of the total activity
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70% of the total activity
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brenda
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TRXR1_PONAB
499
0
54751
Swiss-Prot
other Location (Reliability: 1)
TRXR1_RAT
499
0
54670
Swiss-Prot
other Location (Reliability: 1)
TRXR1_BOVIN
499
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54770
Swiss-Prot
other Location (Reliability: 1)
TRXR1_HUMAN
649
0
70906
Swiss-Prot
other Location (Reliability: 2)
TRXR1_MOUSE
613
0
67084
Swiss-Prot
other Location (Reliability: 3)
TRXR1_PIG
499
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54904
Swiss-Prot
other Location (Reliability: 1)
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100
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no activity after 1 min
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-15°C, pH 7, months, no loss of activity
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partial, separation of subcellular fractions
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Conn, E.E.; Kraemer, L.M.; Liu, P.N.; Vennesland, B.
The aerobic oxidation of recuced triphosphopyridine nucleotide by a wheat germ enzyme system
J. Biol. Chem.
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143-151
1952
Triticum aestivum
brenda
DeBari, V.A.; Neddle, M.A.; Bennun, A.
Catalase as a manganese-dependent NADPH peroxidase
609th Meeting, Leeds, Biochemical Society Transactions
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125-126
1985
Homo sapiens
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brenda
Davydova, M.N.; Sabirova, R.Z.
Anti-oxidant defense of the cell Desulfovibrio desulfuricans B-1388
Anaerobe
9
39-41
2003
Desulfovibrio desulfuricans, Desulfovibrio desulfuricans B-1388
brenda
Graber, J.R.; Breznak, J.A.
Physiology and nutrition of Treponema primitia, an H2/CO2-acetogenic spirochete from termite hindguts
Appl. Environ. Microbiol.
70
1307-1314
2004
Treponema primitia
brenda
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1.11.1.2 NADPH peroxidase
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