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IUBMB Comments Acts on long-chain fatty acids from dodecanoic to octadecanoic acid.
The enzyme appears in viruses and cellular organisms
Synonyms fatty acid peroxidase, more
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fatty acid peroxidase
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long chain fatty acid peroxidase
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palmitate + 2 H2O2 = pentadecanal + CO2 + 3 H2O
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hexadecanoate:hydrogen-peroxide oxidoreductase
Acts on long-chain fatty acids from dodecanoic to octadecanoic acid.
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lauric acid + H2O2
undecanal + CO2 + H2O
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Substrates: - Products: -
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palmitate + H2O2
pentadecanal + CO2 + H2O
additional information
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palmitate + H2O2
pentadecanal + CO2 + H2O
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Substrates: - Products: -
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palmitate + H2O2
pentadecanal + CO2 + H2O
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Substrates: breakdown of long chain fatty acids Products: -
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palmitate + H2O2
pentadecanal + CO2 + H2O
Carthamus tintorius
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Substrates: - Products: -
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palmitate + H2O2
pentadecanal + CO2 + H2O
Carthamus tintorius
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Substrates: breakdown of long chain fatty acids Products: -
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palmitate + H2O2
pentadecanal + CO2 + H2O
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Substrates: - Products: -
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palmitate + H2O2
pentadecanal + CO2 + H2O
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Substrates: - Products: (R)-2-hydroxypalmitic acid and pentadecanoic acid also detected as products
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additional information
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Substrates: oxidizes long chain fatty acids, produces CO2 and long chain aldehyde Products: -
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additional information
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Carthamus tintorius
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Substrates: oxidizes long chain fatty acids, produces CO2 and long chain aldehyde Products: -
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palmitate + H2O2
pentadecanal + CO2 + H2O
palmitate + H2O2
pentadecanal + CO2 + H2O
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Substrates: breakdown of long chain fatty acids Products: -
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palmitate + H2O2
pentadecanal + CO2 + H2O
Carthamus tintorius
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Substrates: breakdown of long chain fatty acids Products: -
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palmitate + H2O2
pentadecanal + CO2 + H2O
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Substrates: - Products: -
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CO
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light-dependent inhibition
additional information
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imidazole derivates are also inhibitory, weaker inhibition than imidazole
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2.9
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purified enzyme with lauric acid as substrate
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6.8 - 8
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highest activity
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Carthamus tintorius
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no activity in Glycine max
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no activity in Helianthus annuus
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no activity in Lupinus luteus
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no activity in Rattus norvegicus
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no activity in Ricinus communis
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taken from germinating peanut
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Highest Expressing Human Cell Lines
Filter by:
Cell Line Links
Gene Links
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50000
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alpha,beta, 1 * 70000 + 1 * 50000, 70 kD subunit shows EC 1.11.1.3 activity, 50 kD subunit shows NAD+ oxidoreductase activity
70000
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alpha,beta, 1 * 70000 + 1 * 50000, 70 kD subunit shows EC 1.11.1.3 activity, 50 kD subunit shows NAD+ oxidoreductase activity
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dimer
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alpha,beta, 1 * 70000 + 1 * 50000, 70 kD subunit shows EC 1.11.1.3 activity, 50 kD subunit shows NAD+ oxidoreductase activity
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55
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only traces of activity after 5 min
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-5°C, 3 month, 10% loss of activity
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Martin, R.O.; Stumpf, P.K.
Fat metabolism in higher plants: XII alpha-Oxidation of long chain fatty acids
J. Biol. Chem.
234
2548-2554
1959
Arachis hypogaea, Carthamus tintorius, no activity in Glycine max, no activity in Helianthus annuus, no activity in Lupinus luteus, no activity in Rattus norvegicus, no activity in Ricinus communis
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Saffert, A.; Hartmann-Schreier, J.; Schon, A.; Schreier, P.
A dual function alpha-dioxygenase-peroxidase and NAD+ oxidoreductase active enzyme from germinating pea rationalizing alpha-oxidation of fatty acids in plants
Plant Physiol.
123
1545-1551
2000
Pisum sativum
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