Disease on EC 1.13.11.27 - 4-hydroxyphenylpyruvate dioxygenase

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4-hydroxyphenylpyruvate dioxygenase deficiency
Chronic tyrosinemia associated with 4-hydroxyphenylpyruvate dioxygenase deficiency with acute intermittent ataxia and without visceral and bone involvement.
Hepatorenal tyrosinemia.
In vivo correction with recombinant adenovirus of 4-hydroxyphenylpyruvic acid dioxygenase deficiencies in strain III mice.
Tyrosinemia type III: diagnosis and ten-year follow-up.
Urinary excretion of deuterated metabolites in patients with tyrosinemia type I after oral loading with deuterated L-tyrosine.
Adenocarcinoma
A population-based association study of SNPs of GSTP1, MnSOD, GPX2 and Barrett's esophagus and esophageal adenocarcinoma.
NF-kappaB-dependent MnSOD expression protects adenocarcinoma cells from TNF-alpha-induced apoptosis.
Tumor immunolocalization using 124 I-iodine-labeled JAA-F11 antibody to Thomsen-Friedenreich alpha-linked antigen.
Adenocarcinoma of Lung
Activation of NF-kappa B and elevation of MnSOD gene expression by thiol reducing agents in lung adenocarcinoma (A549) cells.
MnSOD overexpression confers cisplatin resistance in lung adenocarcinoma via the NF-?B/Snail/Bcl-2 pathway.
MnSOD Promotes Tumor Invasion via Upregulation of FoxM1-MMP2 Axis and Related with Poor Survival and Relapse in Lung Adenocarcinomas.
Adenoma
The MnSOD A16V mitochondrial targeting sequence polymorphism is not associated with increased risk of distal colorectal adenomas: data from a sigmoidoscopy-based case control study.
Airway Obstruction
The fusion protein of respiratory syncytial virus triggers p53-dependent apoptosis.
Alkaptonuria
A novel therapeutic trial of homogentisic aciduria in a murine model of alkaptonuria.
Pyrazolone-quinazolone hybrids: a novel class of human 4-hydroxyphenylpyruvate dioxygenase inhibitors.
Use of nitisinone in patients with alkaptonuria.
Alzheimer Disease
Lack of association between MnSOD gene polymorphism and sporadic Alzheimer's disease.
Loss in PKC Epsilon Causes Downregulation of MnSOD and BDNF Expression in Neurons of Alzheimer's Disease Hippocampus.
Role of genes GSTM1, GSTT1, and MnSOD in the development of late-onset Alzheimer disease and their relationship with APOE*4.
The effects of different antioxidants on the activity of cerebrocortical MnSOD and Na,K-ATPase from post mortem Alzheimer's disease and age-matched normal brains.
Amyotrophic Lateral Sclerosis
Crystal structures of holo and Cu-deficient Cu/Zn-SOD from the silkworm Bombyx mori and the implications in amyotrophic lateral sclerosis.
CuZnSOD and MnSOD immunoreactivity in brain stem motor neurons from amyotrophic lateral sclerosis patients.
Recessively inherited amyotrophic lateral sclerosis: a Germany family with the D90A CuZn-SOD mutation.
Anemia
Electrostatic Architecture of the Infectious Salmon Anemia Virus (ISAV) Core Fusion Protein Illustrates a Carboxyl-Carboxylate pH Sensor.
Arthritis, Experimental
Protective effects of human recombinant MnSOD in adjuvant arthritis and bleomycin-induced lung fibrosis.
Arthritis, Rheumatoid
Effect of lentivirus-mediated overexpression or silencing of MnSOD on apoptosis of resveratrol-treated fibroblast-like synoviocytes in rheumatoid arthritis.
Ataxia
Chronic tyrosinemia associated with 4-hydroxyphenylpyruvate dioxygenase deficiency with acute intermittent ataxia and without visceral and bone involvement.
In vivo correction with recombinant adenovirus of 4-hydroxyphenylpyruvic acid dioxygenase deficiencies in strain III mice.
Barrett Esophagus
A population-based association study of SNPs of GSTP1, MnSOD, GPX2 and Barrett's esophagus and esophageal adenocarcinoma.
Exposure to bile acids alters the intracellular location and function of MnSOD in Barrett's esophagus.
Blister
Development of tissue-targeting hemagglutinating virus of Japan envelope vector for successful delivery of therapeutic gene to mouse skin.
Brain Injuries
ALS-linked Cu/Zn-SOD mutation impairs cerebral synaptic glucose and glutamate transport and exacerbates ischemic brain injury.
Brain Injuries, Traumatic
CuZn-SOD deficiency, rather than overexpression, is associated with enhanced recovery and attenuated activation of NF-kappaB after brain trauma in mice.
Brain Neoplasms
The level of MnSOD is directly correlated with grade of brain tumours of neuroepithelial origin.
Breast Neoplasms
Anti-Thomsen-Friedenreich-Ag (anti-TF-Ag) potential for cancer therapy.
Associations of polymorphic variant of MnSOD gene with breast cancer in residents of the Altai Region.
Breast cancer risk and polymorphisms in genes involved in metabolism of estrogens (CYP17, HSD17beta1, COMT and MnSOD): Possible protective role of MnSOD gene polymorphism Val/Ala and Ala/Ala in women that never breast fed.
Combined effect of CYP1B1, COMT, GSTP1, and MnSOD genotypes and risk of postmenopausal breast cancer.
Gene x Gene interaction between MnSOD and GPX-1 and breast cancer risk: a nested case-control study.
High expression of MnSOD promotes survival of circulating breast cancer cells and increases their resistance to doxorubicin.
Humanization of JAA-F11, a Highly Specific Anti-Thomsen-Friedenreich Pancarcinoma Antibody and InVitro Efficacy Analysis.
Increased oxidative stress created by adenoviral MnSOD or CuZnSOD plus BCNU (1,3-bis(2-chloroethyl)-1-nitrosourea) inhibits breast cancer cell growth.
Inhibition of mTOR sensitizes breast cancer stem cells to radiation-induced repression of self-renewal through the regulation of MnSOD and Akt.
Lack of association between MnSOD Val16Ala polymorphism and breast cancer risk: a meta-analysis involving 58,448 subjects.
MnSOD and CAT polymorphisms modulate the effect of the Mediterranean diet on breast cancer risk among Greek-Cypriot women.
MnSOD expression is less frequent in tumour cells of invasive breast carcinomas than in in situ carcinomas or non-neoplastic breast epithelial cells.
MnSOD polymorphism and breast cancer in a population-based case-control study.
MnSOD rs4880 and XPD rs13181 polymorphisms predict the survival of breast cancer patients treated with adjuvant tamoxifen.
MnSOD Val-9Ala genotype, pro- and anti-oxidant environmental modifiers, and breast cancer among women on Long Island, New York.
Physical interaction of estrogen receptor with MnSOD: implication in mitochondrial O2(.-) upregulation and mTORC2 potentiation in estrogen-responsive breast cancer cells.
Polymorphisms in genes related to oxidative stress (CAT, MnSOD, MPO, and eNOS) and acute toxicities from radiation therapy following lumpectomy for breast cancer.
Polymorphisms in genes related to oxidative stress (MPO, MnSOD, CAT) and survival after treatment for breast cancer.
Possible risk modifications in the association between MnSOD Ala-9Val polymorphism and breast cancer risk: subgroup analysis and evidence-based sample size calculation for a future trial.
Resistance to TNF-alpha and adriamycin in the human breast cancer MCF-7 cell line: relationship to MDR1, MnSOD, and TNF gene expression.
Targeting MnSOD in Basal Breast Carcinoma using Agonists of PPAR?: a new strategy for enhancing chemosensitivity.
Bronchiolitis, Viral
Respiratory syncytial virus fusion protein promotes TLR-4-dependent neutrophil extracellular trap formation by human neutrophils.
Bronchopulmonary Dysplasia
Safety and immunogenicity of a purified F protein respiratory syncytial virus (PFP-2) vaccine in seropositive children with bronchopulmonary dysplasia.
Carcinogenesis
Hepatitis C virus F protein: A double-edged sword in the potential contribution of chronic inflammation to carcinogenesis.
Regulation of MnSOD Enzymatic Activity by Sirt3 Connects the Mitochondrial Acetylome Signaling Networks to Aging and Carcinogenesis.
[Association of single nucleotide polymorphism of MnSOD gene with carcinogenesis and development of esophageal squamous cell carcinoma]
Carcinoma
Engineered serine protease inhibitor prevents furin-catalyzed activation of the fusion glycoprotein and production of infectious measles virus.
Jaa-f11: extending the life of mice with breast cancer.
MnSOD expression is less frequent in tumour cells of invasive breast carcinomas than in in situ carcinomas or non-neoplastic breast epithelial cells.
[Association of single nucleotide polymorphism of MnSOD gene with carcinogenesis and development of esophageal squamous cell carcinoma]
[Expression of MnSOD mRNA and protein in esophageal squamous cell carcinoma and its clinical significance].
Carcinoma, Hepatocellular
Comparative sequence analysis of the core protein and its frameshift product, the F protein, of hepatitis C virus subtype 1b strains obtained from patients with and without hepatocellular carcinoma.
Distinct hepatitis C virus core and F protein quasispecies in tumoral and nontumoral hepatocytes isolated via microdissection.
Hepatitis C virus f protein is a short-lived protein associated with the endoplasmic reticulum.
Hepatitis C virus F protein up-regulates c-myc and down-regulates p53 in human hepatoma HepG2 cells.
Hepatitis C virus F protein: A double-edged sword in the potential contribution of chronic inflammation to carcinogenesis.
Induction of MnSOD gene by arachidonic acid is mediated by reactive oxygen species and p38 MAPK signaling pathway in human HepG2 hepatoma cells.
Th1 and Th2 cytokine profiles induced by hepatitis C virus F protein in peripheral blood mononuclear cells from chronic hepatitis C patients.
Carcinoma, Ovarian Epithelial
D-4F, an apoA-I mimetic peptide, inhibits proliferation and tumorigenicity of epithelial ovarian cancer cells by upregulating the anti-oxidant enzyme MnSOD.
Manganese superoxide dismutase gene polymorphism, MnSOD plasma levels and risk of epithelial ovarian cancer.
Carcinoma, Squamous Cell
Transfection and expression of MnSOD cDNA decreases tumor malignancy of human oral squamous carcinoma SCC-25 cells.
Cardiomyopathies
Opposite effects of catalase and MnSOD ectopic expression on stress induced defects and mortality in the desmin deficient cardiomyopathy model.
The absence of cardiomyopathy is accompanied by increased activities of CAT, MnSOD and GST in long-term diabetes in rats.
Cardiotoxicity
The protective effect of cardiac gene transfer of CuZn-sod in comparison with the cardioprotector monohydroxyethylrutoside against doxorubicin-induced cardiotoxicity in cultured cells.
Carotid Artery Diseases
The signal sequence polymorphism of the MnSOD gene is associated with the degree of carotid atherosclerosis.
Cataract
Glucose-induced cataract in CuZn-SOD null lenses: an effect of nitric oxide?
Cholera
Effective mucosal immunization against respiratory syncytial virus using purified F protein and a genetically detoxified cholera holotoxin, CT-E29H.
Respiratory syncytial virus recombinant F protein (residues 255-278) induces a helper T cell type 1 immune response in mice.
Coinfection
Characterization of Newcastle disease virus envelope glycoproteins expressed in insect cells.
Colonic Neoplasms
Sirtuin 3 silencing improves oxaliplatin efficacy through acetylation of MnSOD in colon cancer.
Colorectal Neoplasms
Determination of gene expression and serum levels of MnSOD and GPX1 in colorectal cancer.
Expression of the xenobiotic- and reactive oxygen species-detoxifying enzymes, GST-pi, Cu/Zn-SOD, and Mn-SOD in the endocrine cells of colorectal cancer.
Genetic and epigenetic down-regulation of microRNA-212 promotes colorectal tumor metastasis via dysregulation of MnSOD.
MnSOD inhibits proline oxidase-induced apoptosis in colorectal cancer cells.
MnSOD protects colorectal cancer cells from TRAIL-induced apoptosis by inhibition of Smac/DIABLO release.
Corneal Opacity
Tyrosinemia produced by 2-(2-nitro-4-trifluoromethylbenzoyl)-cyclohexane-1,3-dione (NTBC) in experimental animals and its relationship to corneal injury.
Coronary Artery Disease
MnSOD, CAT and GPx-3 genetic polymorphisms in coronary artery disease.
Coronary Disease
MnSOD and GPx1 polymorphism relationship with coronary heart disease risk and severity.
Dengue
A Study on Gene Expression Profile of Endogenous Antioxidant Enzymes: CAT, MnSOD and GPx in Dengue Patients.
Diabetes, Gestational
Skeletal Muscle MnSOD, Mitochondrial Complex II, and SIRT3 Enzyme Activities Are Decreased in Maternal Obesity During Human Pregnancy and Gestational Diabetes Mellitus.
Diabetic Cardiomyopathies
Protection of Cardiac Mitochondria by Overexpression of MnSOD Reduces Diabetic Cardiomyopathy.
Diabetic Nephropathies
CNDP1, NOS3, and MnSOD Polymorphisms as Risk Factors for Diabetic Nephropathy among Type 2 Diabetic Patients in Malaysia.
Diabetic Retinopathy
Association of RAGE (p.Gly82Ser) and MnSOD (p.Val16Ala) polymorphisms with diabetic retinopathy in T2DM patients from north India.
Expression modification of uncoupling proteins and MnSOD in retinal endothelial cells and pericytes induced by high glucose: The role of reactive oxygen species in diabetic retinopathy.
Distemper
Amino-terminal precursor sequence modulates canine distemper virus fusion protein function.
Canine distemper virus and measles virus fusion glycoprotein trimers: partial membrane-proximal ectodomain cleavage enhances function.
Conserved leucine residue in the head region of morbillivirus fusion protein regulates the large conformational change during fusion activity.
Immunological relationships between phocid and canine distemper virus studied with monoclonal antibodies.
Induction of castration by immunization of male dogs with recombinant gonadotropin-releasing hormone (GnRH)-canine distemper virus (CDV) T helper cell epitope p35.
Interaction of a synthetic peptide corresponding to the N-terminus of canine distemper virus fusion protein with phospholipid vesicles: a biophysical study.
Measles virus fusion protein is palmitoylated on transmembrane-intracytoplasmic cysteine residues which participate in cell fusion.
The fusion protein gene of phocine distemper virus: nucleotide and deduced amino acid sequences and a comparison of morbillivirus fusion proteins.
The nucleotide and predicted amino acid sequence of the fusion protein of recent isolates of canine distemper virus in Japan.
The nucleotide sequence of the gene encoding the F protein of canine distemper virus: a comparison of the deduced amino acid sequence with other paramyxoviruses.
Totally synthetic peptide-based immunocontraceptive vaccines show activity in dogs of different breeds.
[Significance of paramyxovirinae protein F in physiopathology and immunity]
Down Syndrome
Down syndrome and Cu/Zn-SOD: an additional interpretation.
Transgenic mice overexpressing the human Cu/Zn-SOD gene: ultrastructural studies of a premature thymic involution model of Down's syndrome (trisomy 21).
Dyskinesias
Association between the MnSOD Ala-9Val polymorphism and development of schizophrenia and abnormal involuntary movements in the Xhosa population.
Encephalitis
Protective role of human antibody to the fusion protein of measles virus.
Endometrial Neoplasms
Relation of MPO, MnSOD, NQO1 gene variants in endometrial carcinoma in the line of PCR-RFLP methods.
Epidermolysis Bullosa
Development of tissue-targeting hemagglutinating virus of Japan envelope vector for successful delivery of therapeutic gene to mouse skin.
Esophageal Neoplasms
[Bidirectional effect of MnSOD overexpression on the proliferation of esophageal cancer cells in vitro].
Esophageal Squamous Cell Carcinoma
[Association of single nucleotide polymorphism of MnSOD gene with carcinogenesis and development of esophageal squamous cell carcinoma]
[Expression of MnSOD mRNA and protein in esophageal squamous cell carcinoma and its clinical significance].
Essential Hypertension
Evidence for an association between haptoglobin and MnSOD (Val9Ala) gene polymorphisms in essential hypertension based on a Brazilian case-control study.
Fanconi Anemia
RNAi-mediated knockdown of FANCF suppresses cell proliferation, migration, invasion, and drug resistance potential of breast cancer cells.
The antitumor agent doxorubicin binds to Fanconi anemia group F protein.
The Fanconi anemia pathway sensitizes to DNA alkylating agents by inducing JNK-p53-dependent mitochondrial apoptosis in breast cancer cells.
Fibrosarcoma
Oncolytic efficacy and enhanced safety of measles virus activated by tumor-secreted matrix metalloproteinases.
Overexpression of MnSOD protects murine fibrosarcoma cells (FSa-II) from apoptosis and promotes a differentiation program upon treatment with 5-azacytidine: involvement of MAPK and NFkappaB pathways.
Fowlpox
Newcastle disease virus fusion protein expressed in a fowlpox virus recombinant confers protection in chickens.
Glioblastoma
LRIG1 improves chemosensitivity through inhibition of BCL-2 and MnSOD in glioblastoma.
Glioma
Demethoxycurcumin mediated targeting of MnSOD leading to activation of apoptotic pathway and inhibition of Akt/NF-?B survival signalling in human glioma U87 MG cells.
Graves Disease
Identification of outer membrane porin f protein of Yersinia enterocolitica recognized by antithyrotopin receptor antibodies in Graves' disease and determination of its epitope using mass spectrometry and bioinformatics tools.
Heart Arrest
Mild hypothermia attenuates mitochondrial oxidative stress by protecting respiratory enzymes and upregulating MnSOD in a pig model of cardiac arrest.
Heart Diseases
Respiratory syncytial virus infections in infants affected by primary immunodeficiency.
[Respiratory syncytial virus infection]
[Respiratory syncytial virus]
Heart Failure
EGCG, a green tea catechin, attenuates the progression of heart failure induced by the heart/muscle-specific deletion of MnSOD in mice.
MnSOD protects against COX1-mediated endothelial dysfunction in chronic heart failure.
Hepatitis B
Synthesis of a novel hepatitis C virus protein by ribosomal frameshift.
Hepatitis C
Antigenic relevance of F protein in chronic hepatitis C virus infection.
Assessment of specific antibodies to F protein in serum samples from Chinese hepatitis C patients treated with interferon plus ribavarin.
Characterization of humoral and cell-mediated immune responses directed against hepatitis C virus F protein in subjects co-infected with hepatitis C virus and HIV-1.
Characterization of the expression of the hepatitis C virus F protein.
Comparative sequence analysis of the core protein and its frameshift product, the F protein, of hepatitis C virus subtype 1b strains obtained from patients with and without hepatocellular carcinoma.
Development of specific antibodies to an ARF protein in treated patients with chronic HCV infection.
Differential reactivity of putative genotype 2 hepatitis C virus F protein between chronic and recovered infections.
Distinct hepatitis C virus core and F protein quasispecies in tumoral and nontumoral hepatocytes isolated via microdissection.
Genetic variants in human leukocyte antigen-DP influence both hepatitis C virus persistence and hepatitis C virus F protein generation in the Chinese Han population.
Hepatitis C virus F protein inhibits cell apoptosis by activation of intracellular NF-kappaB pathway.
Hepatitis C virus f protein is a short-lived protein associated with the endoplasmic reticulum.
Hepatitis C virus F protein sequence reveals a lack of functional constraints and a variable pattern of amino acid substitution.
Hepatitis C virus F protein up-regulates c-myc and down-regulates p53 in human hepatoma HepG2 cells.
Hepatitis C virus F protein: A double-edged sword in the potential contribution of chronic inflammation to carcinogenesis.
Interaction of hepatitis C virus F protein with prefoldin 2 perturbs tubulin cytoskeleton organization.
Memory T-cell-mediated immune responses specific to an alternative core protein in hepatitis C virus infection.
Screening of hepatocyte proteins binding to F protein of hepatitis C virus by yeast two-hybrid system.
Th1 and Th2 cytokine profiles induced by hepatitis C virus F protein in peripheral blood mononuclear cells from chronic hepatitis C patients.
Translation of the F protein of hepatitis C virus is initiated at a non-AUG codon in a +1 reading frame relative to the polyprotein.
Triple decoding of hepatitis C virus RNA by programmed translational frameshifting.
Ubiquitin-independent degradation of hepatitis C virus F protein.
[Antigenicity of hepatitis C virus F protein and serum prevalence of anti-F in HCV-infected patients]
[Hepatitis C virus F protein-mediated inhibition of hepatoma cell proliferation].
[Influence of F protein of hepatitis C virus subtype 1b inhibits on human hepatocellular carcinom HepG2 cell apoptosis]
[Screening and cloning target genes transactivated by hepatitis C virus F protein using suppression subtractive hybridization technique]
Hepatitis C, Chronic
Antigenic relevance of F protein in chronic hepatitis C virus infection.
Characterization of the specific CD4+ T cell response against the F protein during chronic hepatitis C virus infection.
F protein increases CD4+CD25+ T cell population in patients with chronic hepatitis C.
Hepatitis C virus alternate reading frame protein decreases interferon-? secretion in peripheral blood mononuclear cells.
Th1 and Th2 cytokine profiles induced by hepatitis C virus F protein in peripheral blood mononuclear cells from chronic hepatitis C patients.
[The detection of antibodies to HCV F protein with immune enzyme analysis using synthetic peptide.]
Hyperalgesia
Hydrogen-rich saline prevents remifentanil-induced hyperalgesia and inhibits MnSOD nitration via regulation of NR2B-containing NMDA receptor in rats.
Hypersensitivity
Measles virus fusion protein presented in an immune-stimulating complex (iscom) induces haemolysis-inhibiting and fusion-inhibiting antibodies, virus-specific T cells and protection in mice.
MnSOD polymorphisms in sensitized patients with delayed-type hypersensitivity reactions to the chemical allergen para-phenylene diamine: a case-control study.
Ichthyosis
Crystallization of the xeroderma pigmentosum group F endonuclease from Aeropyrum pernix.
Infection
A chimeric A2 strain of respiratory syncytial virus (RSV) with the fusion protein of RSV strain line 19 exhibits enhanced viral load, mucus, and airway dysfunction.
A conformational epitope on the dimer of the fusion protein of respiratory syncytial virus detected in natural infections.
Age-Specific Profiles of Antibody Responses against Respiratory Syncytial Virus Infection.
Antibody-Induced Internalization of the Human Respiratory Syncytial Virus Fusion Protein.
Blocking intercellular adhesion molecule-1 on human epithelial cells decreases respiratory syncytial virus infection.
Budding site of Sendai virus in polarized epithelial cells is one of the determinants for tropism and pathogenicity in mice.
Building a better neonatal mouse model to understand infant respiratory syncytial virus disease.
Changes in specific cleavability of the Sendai virus fusion protein: implications for pathogenicity in mice.
Characterization of an alternate form of Newcastle disease virus fusion protein.
Characterization of Newcastle disease virus envelope glycoproteins expressed in insect cells.
Characterization of Sendai virus persistently infected L929 cells and Sendai virus pi strain: recombinant Sendai viruses having Mpi protein shows lower cytotoxicity and are incapable of establishing persistent infection.
Characterization of the specific CD4+ T cell response against the F protein during chronic hepatitis C virus infection.
Characterization of two monoclonal antibodies, 38F10 and 44D11, against the major envelope fusion protein of Helicoverpa armigera nucleopolyhedrovirus.
Comparison of Palivizumab-Like Antibody Binding to Different Conformations of the RSV F Protein in RSV-Infected Adult Hematopoietic Cell Transplant Recipients.
Cotton rat immune responses to virus-like particles containing the pre-fusion form of respiratory syncytial virus fusion protein.
Cross-neutralization of four paramyxoviruses by a human monoclonal antibody.
Determinants of pantropism of the F1-R mutant of Sendai virus: specific mutations involved are in the F and M genes.
Development of specific antibodies to an ARF protein in treated patients with chronic HCV infection.
Differential reactivity of putative genotype 2 hepatitis C virus F protein between chronic and recovered infections.
Discovery of a Prefusion Respiratory Syncytial Virus F-Specific Monoclonal Antibody That Provides Greater In Vivo Protection than the Murine Precursor of Palivizumab.
Dual functions of a 4-hydroxyphenylpyruvate dioxygenase for Vibrio splendidus survival and infection.
Effect of Previous Respiratory Syncytial Virus Infection on Murine Immune Responses to F and G Protein Containing Virus-like Particles.
EGFR Interacts with the Fusion Protein of Respiratory Syncytial Virus Strain 2-20 and Mediates Infection and Mucin Expression.
Electrostatic Architecture of the Infectious Salmon Anemia Virus (ISAV) Core Fusion Protein Illustrates a Carboxyl-Carboxylate pH Sensor.
First field evidence of the evolution from a non-virulent HPR0 to a virulent HPR-deleted infectious salmon anaemia virus.
Functions of surface glycoproteins of myxoviruses and paramyxoviruses and their inhibition.
Genetic variations of IL-28B and PD-1 are in association with the susceptibility and outcomes of HCV infection in Southeast China.
HCV F protein amplifies the predictions of IL-28B and CTLA-4 polymorphisms about the susceptibility and outcomes of HCV infection in Southeast China.
Hepatitis C virus alternate reading frame protein decreases interferon-? secretion in peripheral blood mononuclear cells.
Hepatitis C virus F protein: A double-edged sword in the potential contribution of chronic inflammation to carcinogenesis.
Human antibody responses to mature and immature forms of viral envelope in respiratory syncytial virus infection: significance for subunit vaccines.
Human metapneumovirus fusion protein vaccines that are immunogenic and protective in cotton rats.
Identification of a Human Respiratory Syncytial Virus Cell Entry Inhibitor by Using a Novel Lentiviral Pseudotype System.
Immunogenicity and safety of respiratory syncytial virus subunit vaccine in seropositive children 18-36 months old.
Immunoglobulin g antibody-mediated enhancement of measles virus infection can bypass the protective antiviral immune response.
Inhibiting Human Parainfluenza Virus Infection by Preactivating the Cell Entry Mechanism.
Inhibition of respiratory syncytial virus infection with the CC chemokine RANTES (CCL5).
Integrin ?v?1 Modulation Affects Subtype B Avian Metapneumovirus Fusion Protein-mediated Cell-Cell Fusion and Virus Infection.
Interaction of hepatitis C virus F protein with prefoldin 2 perturbs tubulin cytoskeleton organization.
Intranasal immunization with W 80 5EC adjuvanted recombinant RSV rF-ptn enhances clearance of respiratory syncytial virus in a mouse model.
Isolation and characterization of monoclonal antibodies which neutralize human metapneumovirus in vitro and in vivo.
Lactoferrin and surfactant protein A exhibit distinct binding specificity to F protein and differently modulate respiratory syncytial virus infection.
Measles virus spreads in rat hippocampal neurons by cell-to-cell contact and in a polarized fashion.
Molecular characterization of respiratory syncytial viruses infecting children reported to have received palivizumab immunoprophylaxis.
Monoclonal antibodies in pediatrics: use in prevention and treatment.
Morphogenesis of respiratory syncytial virus in human primary nasal ciliated epithelial cells occurs at surface membrane microdomains that are distinct from cilia.
Neutralizing and enhancing activities of human respiratory syncytial virus-specific antibodies.
Neutralizing epitopes of RSV and palivizumab resistance in Japan.
New insights into the mechanism of virus-induced membrane fusion.
Persistent and lytic infections with SSPE virus: a comparison of the synthesis of virus-specific polypeptides.
Production and characterization of neutralizing monoclonal antibodies against human metapneumovirus F protein.
Prokaryotic expression of f protein from PPRV and characterization of its polyclonal antibody.
Protective epitopes on the fusion protein of respiratory syncytial virus recognized by murine and bovine monoclonal antibodies.
Protective role of human antibody to the fusion protein of measles virus.
Pulmonary V gamma 4+ gamma delta T cells have proinflammatory and antiviral effects in viral lung disease.
Recombinant respiratory syncytial virus F protein expression is hindered by inefficient nuclear export and mRNA processing.
Residues in the heptad repeat a region of the fusion protein modulate the virulence of Sendai virus in mice.
Respiratory syncytial virus infects the Bonnet monkey, Macaca radiata.
Respiratory syncytial virus prolifically infects N2a neuronal cells, leading to TLR4 and nucleolin protein modulations and RSV F protein co-localization with TLR4 and nucleolin.
Respiratory syncytial virus proteins modulate suppressors of cytokine signaling 1 and 3 and the type I interferon response to infection by a toll-like receptor pathway.
Respiratory Syncytial Virus: Targeting the G Protein Provides a New Approach for an Old Problem.
Restriction of fusion protein mRNA as a mechanism of measles virus persistence.
Role of paramyxovirus glycoproteins in the interactions between viral and cell membranes.
Sendai virus-like particles devoid of haemagglutinin-neuraminidase protein infect cells via the human asialoglycoprotein receptor.
Sorting signals in the measles virus wild-type glycoproteins differently influence virus spread in polarized epithelia and lymphocytes.
Structure and function of respiratory syncytial virus surface glycoproteins.
Synthesis of a novel hepatitis C virus protein by ribosomal frameshift.
T helper lymphocyte response to respiratory syncytial virus and its components in patients with respiratory allergy and nonatopic controls.
TBX21 polymorphisms are associated with virus persistence in hepatitis C virus infection patients from a high-risk Chinese population.
The core of the respiratory syncytial virus fusion protein is a trimeric coiled coil.
The functions and inhibition of the membrane glycoproteins of paramyxoviruses and myxoviruses and the role of the measles virus M protein in subacute sclerosing panencephalitis.
The fusion protein of peste des petits ruminants virus is a hemolysin.
The highest prevalence of human metapneumovirus in Ahwaz children accompanied by acute respiratory infections.
The Human Metapneumovirus Fusion Protein Mediates Entry Via an Interaction with RGD-binding Integrins.
The importance of RSV F protein conformation in VLPs in stimulation of neutralizing antibody titers in mice previously infected with RSV.
The relevance of Tim-3 polymorphisms and F protein to the outcomes of HCV infection.
Therapeutic monoclonal antibody treatment targeting respiratory syncytial virus (RSV) G protein mediates viral clearance and reduces the pathogenesis of RSV infection in BALB/c mice.
TMPRSS12 Is an Activating Protease for Subtype B Avian Metapneumovirus.
Ubiquitous activation of the Nipah virus fusion protein does not require a basic amino acid at the cleavage site.
Virus entry is a major determinant of cell tropism of Edmonston and wild-type strains of measles virus as revealed by vesicular stomatitis virus pseudotypes bearing their envelope proteins.
Virus-specific aNtibody, Viral Load and Disease Severity in Respiratory Syncytial Virus Infection.
[Construction and identification of replication deficient recombinant adenovirus encoding F gene of subgroup A human respiratory syncytial virus]
[Generation of recombinant vaccinia virus expressing attachment glycoprotein of Nipah virus]
[Immunobiology of bovine respiratory syncytial virus infections]
[Research Progress in the F Gene and Protein of the Respiratory Syncytial Virus].
Infertility, Female
Polymorphism variant of MnSOD A16V and risk of female infertility in northern Iran.
Inflammatory Bowel Diseases
A Cell-Penetrant Manganese Superoxide Dismutase (MnSOD) Mimic Is Able To Complement MnSOD and Exerts an Antiinflammatory Effect on Cellular and Animal Models of Inflammatory Bowel Diseases.
Influenza in Birds
MDV-1 VP22: a transporter that can selectively deliver proteins into cells.
Influenza, Human
A Novel Influenza Virus Hemagglutinin-Respiratory Syncytial Virus (RSV) Fusion Protein Subunit Vaccine against Influenza and RSV.
A recombinant influenza virus vaccine expressing the F protein of respiratory syncytial virus.
Effect of substitution of hemagglutinin-neuraminidase with influenza hemagglutinin on Sendai virus F protein mediated membrane fusion.
Evidence that TMPRSS2 activates the SARS-coronavirus spike-protein for membrane fusion and reduces viral control by the humoral immune response.
Fusion protein of the paramyxovirus SV5: destabilizing and stabilizing mutants of fusion activation.
Immunogenicity and safety of a respiratory syncytial virus fusion protein (RSV F) nanoparticle vaccine in older adults.
Quantitative measurement of paramyxovirus fusion: differences in requirements of glycoproteins between simian virus 5 and human parainfluenza virus 3 or Newcastle disease virus.
Sequence determination of the Sendai virus fusion protein gene.
Sequence determination of the Sendai virus HN gene and its comparison to the influenza virus glycoproteins.
The nucleotide sequence of the mRNA encoding the fusion protein of measles virus (Edmonston strain): a comparison of fusion proteins from several different paramyxoviruses.
Virus membrane fusion proteins: biological machines that undergo a metamorphosis.
Insulin Resistance
Defects in TLR3 expression and RNase L activation lead to decreased MnSOD expression and insulin resistance in muscle cells of obese people.
Intellectual Disability
In vivo correction with recombinant adenovirus of 4-hydroxyphenylpyruvic acid dioxygenase deficiencies in strain III mice.
Laryngeal Neoplasms
Are there possible associations between MnSOD and GPx1 gene variants for laryngeal cancer risk or disease progression?
Polymorphic variants of MnSOD Val16Ala, CAT-262 C < T and GPx1 Pro198Leu genotypes and the risk of laryngeal cancer in a smoking population.
Leiomyoma
Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
CAT, GPX1, MnSOD, GSTM1, GSTT1, and GSTP1 genetic polymorphisms in chronic myeloid leukemia: a case-control study.
Liver Cirrhosis
Treatment of hereditary tyrosinaemia type I by inhibition of 4-hydroxyphenylpyruvate dioxygenase.
Liver Diseases
Liver damage in long-term anticonvulsant therapy: a serological and histological study.
Plasma glutathione S-transferase and F protein are more sensitive than alanine aminotransferase as markers of paracetamol (acetaminophen)-induced liver damage.
Liver Diseases, Alcoholic
Genetic Association and Gene-Gene Interaction Reveal Genetic Variations in ADH1B, GSTM1 and MnSOD Independently Confer Risk to Alcoholic Liver Diseases in India.
Liver Neoplasms
Treatment of hereditary tyrosinaemia type I by inhibition of 4-hydroxyphenylpyruvate dioxygenase.
Lung Diseases
Absence of Vaccine-enhanced RSV Disease and Changes in Pulmonary Dendritic Cells with Adenovirus-based RSV Vaccine.
Respiratory syncytial virus infections in infants affected by primary immunodeficiency.
Virus-Like Particle Vaccine Containing the F Protein of Respiratory Syncytial Virus Confers Protection without Pulmonary Disease by Modulating Specific Subsets of Dendritic Cells and Effector T Cells.
Lung Diseases, Interstitial
Experimental animal model to analyze the immunobiological responses following vaccination with formalin-inactivated respiratory syncytial virus (FI-RSV).
Immunoprotective activity and safety of a respiratory syncytial virus vaccine: mucosal delivery of fusion glycoprotein with a CpG oligodeoxynucleotide adjuvant.
Lung Injury
Effects of various antioxidants on endotoxin-induced lung injury and gene expression: mRNA expressions of MnSOD, interleukin-1beta and iNOS.
Survival, lung injury, and lung protein nitration in heterozygous MnSOD knockout mice in hyperoxia.
Lung Neoplasms
Analysis of NQO1, GSTP1, and MnSOD genetic polymorphisms on lung cancer risk in Taiwan.
Enhanced antitumor effect of combining TRAIL and MnSOD mediated by CEA-controlled oncolytic adenovirus in lung cancer.
Humanization of JAA-F11, a Highly Specific Anti-Thomsen-Friedenreich Pancarcinoma Antibody and InVitro Efficacy Analysis.
Upregulation of FoxM1 by MnSOD Overexpression Contributes to Cancer Stem-Like Cell Characteristics in the Lung Cancer H460 Cell Line.
Lymphoma, Non-Hodgkin
Prevalence of anticentromere F protein autoantibodies in 347 patients with non-Hodgkin's lymphoma.
Measles
A mimotope from a solid-phase peptide library induces a measles virus-neutralizing and protective antibody response.
A P5 peptide that is homologous to peptide 10 of OprF from Pseudomonas aeruginosa enhances clearance of nontypeable Haemophilus influenzae from acutely infected rat lung in the absence of detectable peptide-specific antibody.
A residue located at the junction of the head and stalk regions of measles virus fusion protein regulates membrane fusion by controlling conformational stability.
AIK-C measles vaccine expressing fusion protein of respiratory syncytial virus induces protective antibodies in cotton rats.
Amino acid substitutions in the heptad repeat A and C regions of the F protein responsible for neurovirulence of measles virus Osaka-1 strain from a patient with subacute sclerosing panencephalitis.
Canine distemper virus (CDV) immune-stimulating complexes (Iscoms), but not measles virus iscoms, protect dogs against CDV infection.
Experimental animal model to analyze the immunobiological responses following vaccination with formalin-inactivated respiratory syncytial virus (FI-RSV).
Further-attenuated measles vaccine: virus passages affect viral surface protein expression, immunogenicity and histopathology pattern in vivo.
Heterogeneity of linear B cell epitopes of the measles virus fusion protein reacting with late convalescent sera.
Human T-lymphotropic virus type 1 peptides in chimeric and multivalent constructs with promiscuous T-cell epitopes enhance immunogenicity and overcome genetic restriction.
Identification of amino acids recognized by syncytium-inhibiting and neutralizing monoclonal antibodies to the human parainfluenza type 3 virus fusion protein.
Inhibition of measles virus-induced cell-cell fusion with a monoclonal antibody directed against the haemagglutinin.
Intracellular processing of measles virus fusion protein.
Measurement of polypeptide- and antigenic site-specific antibodies to measles virus using a competitive enzyme immunoassay.
Mechanisms of loss of foreign gene expression in recombinant vesicular stomatitis viruses.
Molecular characterization of measles virus strains causing subactute sclerosing panencephalitis in France in 1977 and 2007.
Protective role of human antibody to the fusion protein of measles virus.
Recombinant measles AIK-C strain expressing current wild-type hemagglutinin protein.
Recombinant measles virus requiring an exogenous protease for activation of infectivity.
Recycling MHC class I molecules and endosomal peptide loading.
Region between the canine distemper virus M and F genes modulates virulence by controlling fusion protein expression.
Reversible inhibition of the fusion activity of measles virus F protein by an engineered intersubunit disulfide bridge.
Structural features of paramyxovirus F protein required for fusion initiation.
Subacute sclerosing panencephalitis is typically characterized by alterations in the fusion protein cytoplasmic domain of the persisting measles virus.
T cell immunity to measles viral proteins in infants and adults after measles immunization.
Temperature elevation enhances cell surface expression of measles virus fusion protein in infected cells.
The functions and inhibition of the membrane glycoproteins of paramyxoviruses and myxoviruses and the role of the measles virus M protein in subacute sclerosing panencephalitis.
The hemagglutinin of recent measles virus isolates induces cell fusion in a marmoset cell line, but not in other CD46-positive human and monkey cell lines, when expressed together with the F protein.
The influence of orientation and number of copies of T and B cell epitopes on the specificity and affinity of antibodies induced by chimeric peptides.
The nucleotide sequence of the mRNA encoding the fusion protein of measles virus (Edmonston strain): a comparison of fusion proteins from several different paramyxoviruses.
The paramyxovirus fusion protein C-terminal region: mutagenesis indicates an indivisible protein unit.
The relative abundance of two measles virus fusion protein peptide-DR1 complexes expressed by B cells is independent of the form of the antigen.
The transmembrane domain sequence affects the structure and function of the newcastle disease virus fusion protein.
Three monoclonal antibodies against measles virus F protein cross-react with cellular stress proteins.
[Significance of paramyxovirinae protein F in physiopathology and immunity]
[The genetic characteristic analysis of fusion gene measles wild viruses of China in 2006]
[The genetic characteristics analysis of fusion gene of 13 strains measles viruses in China]
Mumps
Canine distemper virus and measles virus fusion glycoprotein trimers: partial membrane-proximal ectodomain cleavage enhances function.
Crystallization and preliminary X-ray diffraction analysis of central structure domains from mumps virus F protein.
Effect on fusion induction of point mutations introduced into the F protein of mumps virus.
Genetic characterization of L-Zagreb mumps vaccine strain.
Identification of an amino acid that defines the fusogenicity of mumps virus.
Identification of conformational neutralization sites on the fusion protein of mumps virus.
Identification of regions on the fusion protein of human parainfluenza virus type 2 which are required for haemagglutinin-neuraminidase proteins to promote cell fusion.
Mumps Virus Matrix, Fusion, and Nucleocapsid Proteins Cooperate for Efficient Production of Virus-Like Particles.
The mumps virus fusion protein mRNA sequence and homology among the paramyxoviridae proteins.
The paramyxovirus fusion protein C-terminal region: mutagenesis indicates an indivisible protein unit.
[Expression and purification of heptad repeat region of the mumps virus F protein and analysis of characteristics]
[Significance of paramyxovirinae protein F in physiopathology and immunity]
Muscular Atrophy
MnSOD deficiency results in elevated oxidative stress and decreased mitochondrial function but does not lead to muscle atrophy during aging.
Myocardial Stunning
Elevated MnSOD is not required for exercise-induced cardioprotection against myocardial stunning.
Nasopharyngeal Carcinoma
[Association of MnSOD single nucleotide polymorphism with the occurrence and clinical outcome of nasopharyngeal carcinoma in Cantonese].
Neoplasm Metastasis
Anti-Thomsen-Friedenreich-Ag (anti-TF-Ag) potential for cancer therapy.
Genetic and epigenetic down-regulation of microRNA-212 promotes colorectal tumor metastasis via dysregulation of MnSOD.
Inhibition of Prostate Cancer Bone Metastasis by Synthetic TF Antigen Mimic/Galectin-3 Inhibitor Lactulose-l-Leucine.
Inhibition of spontaneous breast cancer metastasis by anti-Thomsen-Friedenreich antigen monoclonal antibody JAA-F11.
Preclinical studies with JAA-F11 anti-Thomsen-Friedenreich monoclonal antibody for human breast cancer.
Soluble expression of a human MnSOD and Hirudin fusion protein in Escherichia coli, and its effects on metastasis and invasion of 95-D cells.
Neoplasms
A preliminary estimation of tissue factor pathway inhibitor (TFPI) and protein C in patients with intracranial tumors.
A recombinant MnSOD is radioprotective for normal cells and radiosensitizing for tumor cells.
Activity and protein level of CuZnSOD and MnSOD in benign and malignant liver tumors.
Anti-Thomsen-Friedenreich-Ag (anti-TF-Ag) potential for cancer therapy.
Association between MnSOD Val16Ala Polymorphism and Cancer Risk: Evidence from 33,098 Cases and 37,831 Controls.
B-cell translocation gene 2 mediates crosstalk between PI3K/Akt1 and NFkappaB pathways which enhances transcription of MnSOD by accelerating IkappaBalpha degradation in normal and cancer cells.
Cell surface Thomsen-Friedenreich proteome profiling of metastatic prostate cancer cells reveals potential link with cancer stem cell-like phenotype.
CuZnSOD and MnSOD inhibit metabolic stress-induced necrosis and multicellular tumour spheroid growth.
Defective gene expression of MnSOD in cancer cells.
Development, characterization, and immunotherapeutic use of peptide mimics of the Thomsen-Friedenreich carbohydrate antigen.
Effects of adenovirus-mediated SV5 fusogenic glycoprotein expression on tumor cells.
Expression of CYP1A1, CYP1B1 and MnSOD in a panel of human cancer cell lines.
Functional properties of a 16 kDa protein translated from an alternative open reading frame of the core-encoding genomic region of hepatitis C virus.
Generation of optimized and urokinase-targeted oncolytic Sendai virus vectors applicable for various human malignancies.
Humanization of JAA-F11, a Highly Specific Anti-Thomsen-Friedenreich Pancarcinoma Antibody and InVitro Efficacy Analysis.
Induction of interferon-alpha and tumor necrosis factor-related apoptosis-inducing ligand in human blood mononuclear cells by hemagglutinin-neuraminidase but not F protein of Newcastle disease virus.
Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging.
Mechanism of the tumor suppressive effect of MnSOD overexpression.
MnSOD expression is less frequent in tumour cells of invasive breast carcinomas than in in situ carcinomas or non-neoplastic breast epithelial cells.
MnSOD expression within tumor cells is closely related to mode of invasion in human gastric cancer.
MnSOD Gene Polymorphism Association with Steroid-Dependent Cancer.
MnSOD mediates shear stress-promoted tumor cell migration and adhesion.
MnSOD Promotes Tumor Invasion via Upregulation of FoxM1-MMP2 Axis and Related with Poor Survival and Relapse in Lung Adenocarcinomas.
MnSOD up-regulates maspin tumor suppressor gene expression in human breast and prostate cancer cells.
MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer.
Oncolytic efficacy and enhanced safety of measles virus activated by tumor-secreted matrix metalloproteinases.
Preferential selection of MnSOD transcripts in proliferating normal and cancer cells.
The Fanconi anemia pathway sensitizes to DNA alkylating agents by inducing JNK-p53-dependent mitochondrial apoptosis in breast cancer cells.
The fusion protein of respiratory syncytial virus triggers p53-dependent apoptosis.
The leader peptide of a human rec. MnSOD as molecular carrier which delivers high amounts of cisplatin into tumor cells inducing a fast apoptosis in vitro.
Transfection and expression of MnSOD cDNA decreases tumor malignancy of human oral squamous carcinoma SCC-25 cells.
Tumor immunolocalization using 124 I-iodine-labeled JAA-F11 antibody to Thomsen-Friedenreich alpha-linked antigen.
Tumor necrosis factor and lymphotoxin: protection against oxidative stress through induction of MnSOD.
Tumor necrosis factor-alpha selectively induces MnSOD expression via mitochondria-to-nucleus signaling, whereas interleukin-1beta utilizes an alternative pathway.
Tumor suppressive effects of MnSOD overexpression may involve imbalance in peroxide generation versus peroxide removal.
Upregulation of FoxM1 by MnSOD Overexpression Contributes to Cancer Stem-Like Cell Characteristics in the Lung Cancer H460 Cell Line.
Use of reverse genetics to enhance the oncolytic properties of Newcastle disease virus.
[Antigen-antibody reaction between anti-bovine CuZn-SOD antisera and CuZn-SOD in the blood of cancer patients]
[Effect of point substitutions in the MnSOD, GPX1, and GSTP1 genes on the risk of familial and sporadic breast cancers in residents of Altai Krai].
[Observations on the activity and immunologic properties of CuZn-SOD of whole blood in cancer patients]
Neuroblastoma
MnSOD downregulation induced by extremely low 0.1 mGy single and fractionated X-rays and microgravity treatment in human neuroblastoma cell line, NB-1.
Pre-exposure of neuroblastoma cell line to pulsed electromagnetic field prevents H2 O2 -induced ROS production by increasing MnSOD activity.
Newcastle Disease
A host range mutant of Newcastle disease virus with an altered cleavage site for proteolytic activation of the F protein.
A mutation in the stalk of the newcastle disease virus hemagglutinin-neuraminidase (HN) protein prevents triggering of the F protein despite allowing efficient HN-F complex formation.
A single amino acid change in the Newcastle disease virus fusion protein alters the requirement for HN protein in fusion.
Acidic amino acids increase fusion activity in the specific fusion domain of Newcastle disease virus fusion protein.
Addition of N-glycans in the stalk of the Newcastle disease virus HN protein blocks its interaction with the F protein and prevents fusion.
Amino acid substitutions in the F-specific domain in the stalk of the newcastle disease virus HN protein modulate fusion and interfere with its interaction with the F protein.
Antigenic mapping and functional analysis of the F protein of Newcastle disease virus using monoclonal antibodies.
Comprehensive analysis of amino acid sequence diversity at the F protein cleavage site of Newcastle disease virus in fusogenic activity.
Contribution of the length of the HN protein and the sequence of the F protein cleavage site to Newcastle disease virus pathogenicity.
Coordinate deletion of N-glycans from the heptad repeats of the fusion F protein of Newcastle disease virus yields a hyperfusogenic virus with increased replication, virulence, and immunogenicity.
Crystallization and preliminary X-ray diffraction analysis of post-fusion six-helix bundle core structure from Newcastle disease virus F protein.
Decreased dependence on receptor recognition for the fusion promotion activity of L289A-mutated newcastle disease virus fusion protein correlates with a monoclonal antibody-detected conformational change.
Design and analysis of post-fusion 6-helix bundle of heptad repeat regions from Newcastle disease virus F protein.
Development of a double-monoclonal antibody sandwich ELISA: Tool for chicken interferon-? detection ex vivo.
Effect of cleavage mutants on syncytium formation directed by the wild-type fusion protein of Newcastle disease virus.
Expression of recombinant Newcastle disease virus F protein in Pichia pastoris and its immunogenicity using flagellin as the adjuvant.
Identification of amino acids relevant to three antigenic determinants on the fusion protein of Newcastle disease virus that are involved in fusion inhibition and neutralization.
Immobilization of the N-terminal helix stabilizes prefusion paramyxovirus fusion proteins.
Induction of interferon-alpha and tumor necrosis factor-related apoptosis-inducing ligand in human blood mononuclear cells by hemagglutinin-neuraminidase but not F protein of Newcastle disease virus.
Inhibition of Receptor Binding Stabilizes Newcastle Disease Virus HN and F Protein-Containing Complexes.
Interacting domains of the HN and F proteins of newcastle disease virus.
Isolation, Identification, and Sequencing of a Goose-Derived Newcastle Disease Virus and Determination of Its Pathogenicity.
LaSota fusion (F) cleavage motif-mediated fusion activity is affected by other regions of the F protein from different genotype Newcastle disease virus in a chimeric virus: implication for virulence attenuation.
Localization of a domain on the paramyxovirus attachment protein required for the promotion of cellular fusion by its homologous fusion protein spike.
MDV-1 VP22: a transporter that can selectively deliver proteins into cells.
Molecular characterization of two novel sub-sublineages of pigeon paramyxovirus type 1 in China.
Mutations in the ectodomain of newcastle disease virus fusion protein confer a hemagglutinin-neuraminidase-independent phenotype.
Mutations in the Newcastle disease virus hemagglutinin-neuraminidase protein that interfere with its ability to interact with the homologous F protein in the promotion of fusion.
N-linked glycans with similar location in the fusion protein head modulate paramyxovirus fusion.
Newcastle disease virus f glycoprotein expressed from a recombinant vaccinia virus vector protects chickens against live-virus challenge.
Newcastle disease virus HN protein alters the conformation of the F protein at cell surfaces.
Protection of chickens from Newcastle disease by vaccination with a linear plasmid DNA expressing the F protein of Newcastle disease virus.
Recombinant infectious laryngotracheitis virus expressing Newcastle disease virus F protein protects chickens against infectious laryngotracheitis virus and Newcastle disease virus challenge.
Role of the two sialic acid binding sites on the newcastle disease virus HN protein in triggering the interaction with the F protein required for the promotion of fusion.
Six-helix bundle assembly and characterization of heptad repeat regions from the F protein of Newcastle disease virus.
Structural features of paramyxovirus F protein required for fusion initiation.
Structure and function of a paramyxovirus fusion protein.
Structure of the Newcastle disease virus F protein in the post-fusion conformation.
Studies with cross-linking reagents on the oligomeric form of the paramyxovirus fusion protein.
The 3D structure of the fusion primed Sendai F-protein determined by electron cryomicroscopy.
The cytoplasmic domain of the F protein of Human respiratory syncytial virus is not required for cell fusion.
The paramyxovirus fusion protein C-terminal region: mutagenesis indicates an indivisible protein unit.
The transmembrane domain sequence affects the structure and function of the newcastle disease virus fusion protein.
Virulence of Newcastle disease virus is determined by the cleavage site of the fusion protein and by both the stem region and globular head of the haemagglutinin-neuraminidase protein.
[Efficacy enhancement of a Baculovirus-vectored Newcastle Disease Virus F protein vaccine by chicken GM-CSF and IL-2].
[Significance of paramyxovirinae protein F in physiopathology and immunity]
Obesity
Skeletal Muscle MnSOD, Mitochondrial Complex II, and SIRT3 Enzyme Activities Are Decreased in Maternal Obesity During Human Pregnancy and Gestational Diabetes Mellitus.
Optic Neuritis
Increase of manganese superoxide dismutase, but not of Cu/Zn-SOD, in experimental optic neuritis.
Ovarian Neoplasms
The MnSOD Val9Ala polymorphism, dietary antioxidant intake, risk and survival in ovarian cancer (Australia).
Pancreatitis, Chronic
Genetic polymorphisms of GSTT1, GSTM1, GSTP1, MnSOD, and catalase in nonhereditary chronic pancreatitis: evidence of xenobiotic stress and impaired antioxidant capacity.
Paramyxoviridae Infections
Decreased dependence on receptor recognition for the fusion promotion activity of L289A-mutated newcastle disease virus fusion protein correlates with a monoclonal antibody-detected conformational change.
Effects of multiple amino acids of the parainfluenza virus 5 fusion protein on its haemagglutinin-neuraminidase-independent fusion activity.
Full conversion of the hemagglutinin-neuraminidase specificity of the parainfluenza virus 5 fusion protein by replacement of 21 amino acids in its head region with those of the simian virus 41 fusion protein.
Functional analysis of the transmembrane domain in paramyxovirus F protein-mediated membrane fusion.
Functional interaction of paramyxovirus glycoproteins: identification of a domain in Sendai virus HN which promotes cell fusion.
Functional interactions between the fusion protein and hemagglutinin-neuraminidase of human parainfluenza viruses.
Growth properties and F protein cleavage site sequences of naturally occurring human parainfluenza type 2 viruses.
Identification of domains on the fusion (f) protein trimer that influence the hemagglutinin-neuraminidase specificity of the f protein in mediating cell-cell fusion.
Identification of regions on the fusion protein of human parainfluenza virus type 2 which are required for haemagglutinin-neuraminidase proteins to promote cell fusion.
Implication of respiratory syncytial virus (RSV) F transgene sequence heterogeneity observed in Phase 1 evaluation of MEDI-534, a live attenuated parainfluenza type 3 vectored RSV vaccine.
Localization of a domain on the paramyxovirus attachment protein required for the promotion of cellular fusion by its homologous fusion protein spike.
Membrane-dependent conformation, dynamics, and lipid interactions of the fusion peptide of the paramyxovirus PIV5 from solid-state NMR.
On the stability of parainfluenza virus 5 f proteins.
Proteolytic cleavage of wild type and mutants of the F protein of human parainfluenza virus type 3 by two subtilisin-like endoproteases, furin and Kex2.
Strategic priorities for respiratory syncytial virus (RSV) vaccine development.
Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation.
Studies with cross-linking reagents on the oligomeric form of the paramyxovirus fusion protein.
The aberrant gene-end transcription signal of the matrix m gene of human parainfluenza virus type 3 downregulates fusion f protein expression and the f-specific antibody response in vivo.
The actin cytoskeleton inhibits pore expansion during PIV5 fusion protein-promoted cell-cell fusion.
The paramyxovirus fusion protein C-terminal region: mutagenesis indicates an indivisible protein unit.
The two major human metapneumovirus genetic lineages are highly related antigenically, and the fusion (F) protein is a major contributor to this antigenic relatedness.
Three membrane-proximal amino acids in the human parainfluenza type 2 (HPIV 2) F protein are critical for fusogenic activity.
Toll-like receptor 4 is not involved in host defense against respiratory tract infection with Sendai virus.
Vero/BC-F: an efficient packaging cell line stably expressing F protein to generate single round-infectious human parainfluenza virus type 2 vector.
Parkinson Disease
1-Methyl-4-phenyl-pyridinium time-dependently alters expressions of oxoguanine glycosylase 1 and xeroderma pigmentosum group F protein in PC12 cells.
No association of four candidate genetic variants in MnSOD and SYNIII with Parkinson's disease in two Chinese populations.
Pesticide exposure on southwestern Taiwanese with MnSOD and NQO1 polymorphisms is associated with increased risk of Parkinson's disease.
Val-9Ala and Ile+58Thr polymorphism of MnSOD in Parkinson's disease.
Peripheral Nervous System Diseases
Peripheral neuropathy as the presenting feature of tyrosinaemia type I and effectively treated with an inhibitor of 4-hydroxyphenylpyruvate dioxygenase.
Peritonitis
Investigation into the role of Cu/Zn-SOD delivery system on its antioxidant and antiinflammatory activity in rat model of peritonitis.
Persistent Vegetative State
1H, 15N, and 13C backbone chemical shift assignments, secondary structure, and magnesium-binding characteristics of the Bacillus subtilis response regulator, Spo0F, determined by heteronuclear high-resolution NMR.
Peste-des-Petits-Ruminants
Prokaryotic expression of f protein from PPRV and characterization of its polyclonal antibody.
The fusion protein of peste des petits ruminants virus is a hemolysin.
Pneumoconiosis
Genetic polymorphisms of MnSOD, GSTM1, GSTT1, and OGG1 in coal workers' pneumoconiosis.
Pneumonia
Murine Pneumonia Virus Expressing the Fusion Glycoprotein of Human Respiratory Syncytial Virus from an Added Gene Is Highly Attenuated and Immunogenic in Rhesus Macaques.
The cytoplasmic domain of the F protein of Human respiratory syncytial virus is not required for cell fusion.
Prostatic Neoplasms
Association of MnSOD AA Genotype with the Progression of Prostate Cancer.
Cell surface Thomsen-Friedenreich proteome profiling of metastatic prostate cancer cells reveals potential link with cancer stem cell-like phenotype.
HZ08 suppresses RelB-activated MnSOD expression and enhances Radiosensitivity of prostate Cancer cells.
Increased risk of advanced prostate cancer associated with MnSOD Ala-9-Val gene polymorphism.
Inhibition of Prostate Cancer Bone Metastasis by Synthetic TF Antigen Mimic/Galectin-3 Inhibitor Lactulose-l-Leucine.
MnSOD drives neuroendocrine differentiation, androgen independence, and cell survival in prostate cancer cells.
MnSOD genotype and prostate cancer risk as a function of NAT genotype and smoking status.
MnSOD up-regulates maspin tumor suppressor gene expression in human breast and prostate cancer cells.
MnSOD Val(16)Ala polymorphism and prostate cancer susceptibility: a meta-analysis involving 8,962 Subjects.
Protein-Energy Malnutrition
Tyrosyluria in marasmus.
Pulmonary Disease, Chronic Obstructive
The sequence polymorphism of MnSOD gene in subjects with respiratory insufficiency in COPD.
Rectal Neoplasms
Genetic Polymorphisms in Genes Related to Oxidative Stress (GSTP1, GSTM1, GSTT1, CAT, MnSOD, MPO, eNOS) and Survival of Rectal Cancer Patients after Radiotherapy.
Renal Insufficiency, Chronic
The relationship between MnSOD Val16Ala gene polymorphism and the level of serum total antioxidant capacity with the risk of chronic kidney disease in type 2 diabetic patients: a nested case-control study in the Tehran lipid glucose study.
Reperfusion Injury
MnSOD in mouse heart: acute responses to ischemic preconditioning and ischemia-reperfusion injury.
The involvement of the intracellular superoxide production system in hepatic ischemia-reperfusion injury. In vivo and in vitro experiments using transgenic mice manifesting excessive CuZn-SOD activity.
Respiratory Insufficiency
The sequence polymorphism of MnSOD gene in subjects with respiratory insufficiency in COPD.
Respiratory Syncytial Virus Infections
Lactoferrin and surfactant protein A exhibit distinct binding specificity to F protein and differently modulate respiratory syncytial virus infection.
Respiratory Tract Infections
The core of the respiratory syncytial virus fusion protein is a trimeric coiled coil.
Rheumatic Diseases
[CuZn-SOD determination of sera in patients with rheumatic diseases]
Rinderpest
Fusion glycoprotein (F) of rinderpest virus: entire nucleotide sequence of the F mRNA, and several features of the F protein.
Immune response and protection of cattle and pigs generated by a vaccinia virus recombinant expressing the F protein of rinderpest virus.
Immunization with a vaccinia recombinant expressing the F protein protects rabbits from challenge with a lethal dose of rinderpest virus.
[Primary structure of the F-gene from Rinderpest virus strain K]
Sarcoma, Ewing
NF-kappaB activation prevents apoptotic oxidative stress via an increase of both thioredoxin and MnSOD levels in TNFalpha-treated Ewing sarcoma cells.
Seizures
Antioxidant enzymes in cerebral cortex of immature rats following experimentally-induced seizures: upregulation of mitochondrial MnSOD (SOD2).
In vivo correction with recombinant adenovirus of 4-hydroxyphenylpyruvic acid dioxygenase deficiencies in strain III mice.
Starvation
Tetrahymena gene encodes a protein that is homologous with the liver-specific F-antigen and associated with membranes of the Golgi apparatus and transport vesicles.
Stomach Neoplasms
Mn-SOD and CuZn-SOD polymorphisms and interactions with risk factors in gastric cancer.
MnSOD expression is increased in metastatic gastric cancer.
MnSOD expression within tumor cells is closely related to mode of invasion in human gastric cancer.
Subacute Sclerosing Panencephalitis
Alterations and diversity in the cytoplasmic tail of the fusion protein of subacute sclerosing panencephalitis virus strains isolated in Osaka, Japan.
Amino acid substitutions in the heptad repeat A and C regions of the F protein responsible for neurovirulence of measles virus Osaka-1 strain from a patient with subacute sclerosing panencephalitis.
Analysis of a Subacute Sclerosing Panencephalitis Genotype B3 Virus from the 2009-2010 South African Measles Epidemic Shows That Hyperfusogenic F Proteins Contribute to Measles Virus Infection in the Brain.
Effect of the alterations in the fusion protein of measles virus isolated from brains of patients with subacute sclerosing panencephalitis on syncytium formation.
HN glycoprotein of HVJ (Sendai virus) enhances the selective cytotoxicity of diphtheria toxin fragment A-containing liposomes on subacute sclerosing panencephalitis virus-infected cells.
Measles Virus Mutants Possessing the Fusion Protein with Enhanced Fusion Activity Spread Effectively in Neuronal Cells, but Not in Other Cells, without Causing Strong Cytopathology.
Measurement of polypeptide- and antigenic site-specific antibodies to measles virus using a competitive enzyme immunoassay.
Molecular analysis of structural protein genes of the Yamagata-1 strain of defective subacute sclerosing panencephalitis virus. IV. Nucleotide sequence of the fusion gene.
Molecular characterization of measles virus strains causing subactute sclerosing panencephalitis in France in 1977 and 2007.
Subacute sclerosing panencephalitis is typically characterized by alterations in the fusion protein cytoplasmic domain of the persisting measles virus.
superoxide dismutase deficiency
CuZn-SOD deficiency causes ApoB degradation and induces hepatic lipid accumulation by impaired lipoprotein secretion in mice.
CuZn-SOD deficiency, rather than overexpression, is associated with enhanced recovery and attenuated activation of NF-kappaB after brain trauma in mice.
Effect of aging, MnSOD deficiency, and genetic background on endothelial function: evidence for MnSOD haploinsufficiency.
MnSOD deficiency has a differential effect on disease progression in two different ALS mutant mouse models.
MnSOD deficiency increases endothelial dysfunction in ApoE-deficient mice.
MnSOD deficiency results in elevated oxidative stress and decreased mitochondrial function but does not lead to muscle atrophy during aging.
Transcriptional and phenotypic changes in aorta and aortic valve with aging and MnSOD deficiency in mice.
Tardive Dyskinesia
Antipsychotic-induced tardive dyskinesia and polymorphic variations in COMT, DRD2, CYP1A2 and MnSOD genes: a meta-analysis of pharmacogenetic interactions.
[Pharmacogenetic assessment of antipsychotic-induced tardive dyskinesia: contribution of 5-hydroxytryptamine 2C receptor gene and of a combination of dopamine D3 variant allele (Gly) and MnSOD wild allele (Val)]
Teratocarcinoma
F protein induced fusion of Sendai viral envelopes with mouse teratocarcinoma cells through Le(x)-Le(x) interaction.
Tetanus
Human T-lymphotropic virus type 1 peptides in chimeric and multivalent constructs with promiscuous T-cell epitopes enhance immunogenicity and overcome genetic restriction.
Triple Negative Breast Neoplasms
Humanization of JAA-F11, a Highly Specific Anti-Thomsen-Friedenreich Pancarcinoma Antibody and InVitro Efficacy Analysis.
Tuberculosis
Virtual screening studies to identify novel inhibitors for Sigma F protein of Mycobacterium tuberculosis.
Tyrosinemias
3D Pharmacophore-Based Virtual Screening and Docking Approaches toward the Discovery of Novel HPPD Inhibitors.
4-Hydroxyphenylpyruvate dioxygenase as a drug discovery target.
A murine model for type III tyrosinemia: lack of immunologically detectable 4-hydroxyphenylpyruvic acid dioxygenase enzyme protein in a novel mouse strain with hypertyrosinemia.
A nonsense mutation in the 4-hydroxyphenylpyruvic acid dioxygenase gene (Hpd) causes skipping of the constitutive exon and hypertyrosinemia in mouse strain III.
A novel mutation causing mild, atypical fumarylacetoacetase deficiency (Tyrosinemia type I): a case report.
A syndrome of hereditary tyrosinemia in mink (Mustela vison Schreb.).
Chronic tyrosinemia associated with 4-hydroxyphenylpyruvate dioxygenase deficiency with acute intermittent ataxia and without visceral and bone involvement.
Enzyme defect in a case of tyrosinemia type I, acute form.
Hepatorenal tyrosinemia.
Hereditary tyrosinemia: metabolic studies in a patient with partial p-hydroxyphenylpyruvate hydroxylase activity.
Hydrophobicity-oriented drug design (HODD) of new human 4-hydroxyphenylpyruvate dioxygenase inhibitors.
In vivo correction with recombinant adenovirus of 4-hydroxyphenylpyruvic acid dioxygenase deficiencies in strain III mice.
Increased nitric oxide release by neutrophils of a patient with tyrosinemia type III.
Inhibition of 4-hydroxyphenylpyruvate dioxygenase by 2-(2-nitro-4-trifluoromethylbenzoyl)-cyclohexane-1,3-dione and 2-(2-chloro-4-methanesulfonylbenzoyl)-cyclohexane-1,3-dione.
Manifestation of hawkinsinuria in a patient compound heterozygous for hawkinsinuria and tyrosinemia III.
Mutations in the 4-hydroxyphenylpyruvate dioxygenase gene (HPD) in patients with tyrosinemia type III.
Mutations in the 4-hydroxyphenylpyruvic acid dioxygenase gene are responsible for tyrosinemia type III and hawkinsinuria.
Neonatal hypertyrosinemia and evidence for deficiency of ascorbic acid in Arctic and subarctic peoples.
New Research for Quinazoline-2,4-diones as HPPD Inhibitors Based on 2D-MLR and 3D-QSAR Models.
p-Hydroxyphenylpyruvate dioxygenase is a herbicidal target site for beta-triketones from Leptospermum scoparium.
p-hydroxyphenylpyruvate hydroxylase activity in fine-needle aspiration liver biopsies in hereditary tyrosinemia.
Pyrazolone-quinazolone hybrids: a novel class of human 4-hydroxyphenylpyruvate dioxygenase inhibitors.
Representing and reasoning about protein families using generative and discriminative methods.
Scavenging properties of neutrophil 4-hydroxyphenylpyruvate dioxygenase are based on a hypothesis that does not stand up to scrutiny.
Synthesis and bioevaluation of pyrazole-benzimidazolone hybrids as novel human 4-Hydroxyphenylpyruvate dioxygenase inhibitors.
The discovery and structural requirements of inhibitors of p-hydroxypenylpyruvate dioxygenase.
The effect of a low-protein diet and dietary supplementation of threonine on tyrosine and 2-(2-nitro-4-trifluoromethylbenzoyl) cyclohexane-1,3-dione-induced corneal lesions, the extent of tyrosinemia, and the activity of enzymes involved in tyrosine catabolism in the rat.
The Inhibitory Activity of Plants from Central Argentina on p-Hydroxyphenylpyruvate Dioxygenase. Isolation and Mechanism of Inhibition of a Flavanone from Flourensia oolepis.
Tyrosinemia I, a model for human diseases mediated by 2-oxoacid-utilizing dioxygenases: hepatotoxin suppression by NTBC does not normalize hepatic collagen metabolism.
Tyrosinemia produced by 2-(2-nitro-4-trifluoromethylbenzoyl)-cyclohexane-1,3-dione (NTBC) in experimental animals and its relationship to corneal injury.
Tyrosinemia Type III detected via neonatal screening: management and outcome.
Tyrosinemia type III: diagnosis and ten-year follow-up.
Urinary excretion of deuterated metabolites in patients with tyrosinemia type I after oral loading with deuterated L-tyrosine.
Urinary Bladder Neck Obstruction
Time dependent bladder apoptosis induced by acute bladder outlet obstruction and subsequent emptying is associated with decreased MnSOD expression and Bcl-2/Bax ratio.
Urinary Bladder Neoplasms
Frequency of polymorphisms pro198leu in GPX-1 gene and ile58thr in MnSOD gene in the altitude Ecuadorian population with bladder cancer.
Genetic polymorphisms of MPO, COMT, MnSOD, NQO1, interactions with environmental exposures and bladder cancer risk.
Genetic variants of MnSOD and GPX1 and susceptibility to bladder cancer in a Turkish population.
Single-nucleotide polymorphisms of GPX1 and MnSOD and susceptibility to bladder cancer: a systematic review and meta-analysis.
Vaccinia
Comparison of substrate specificities against the fusion glycoprotein of virulent Newcastle disease virus between a chick embryo fibroblast processing protease and mammalian subtilisin-like proteases.
Differences in the role of the cytoplasmic domain of human parainfluenza virus fusion proteins.
Functional interaction of paramyxovirus glycoproteins: identification of a domain in Sendai virus HN which promotes cell fusion.
Immune response and protection of cattle and pigs generated by a vaccinia virus recombinant expressing the F protein of rinderpest virus.
Immunization with a vaccinia recombinant expressing the F protein protects rabbits from challenge with a lethal dose of rinderpest virus.
Individual roles of N-linked oligosaccharide chains in intracellular transport of the paramyxovirus SV5 fusion protein.
Influence of N-linked oligosaccharide chains on the processing, cell surface expression and function of the measles virus fusion protein.
Intracellular processing of the human respiratory syncytial virus fusion glycoprotein: amino acid substitutions affecting folding, transport and cleavage.
Mechanism of reduction of virus release and cell-cell fusion in persistent canine distemper virus infection.
Newcastle disease virus f glycoprotein expressed from a recombinant vaccinia virus vector protects chickens against live-virus challenge.
Proteolytic cleavage of wild type and mutants of the F protein of human parainfluenza virus type 3 by two subtilisin-like endoproteases, furin and Kex2.
Pulmonary V gamma 4+ gamma delta T cells have proinflammatory and antiviral effects in viral lung disease.
Recombinant vaccinia virus coexpressing the F protein of respiratory syncytial virus (RSV) and interleukin-4 (IL-4) does not inhibit the development of RSV-specific memory cytotoxic T lymphocytes, whereas priming is diminished in the presence of high levels of IL-2 or gamma interferon.
Relevance of viral context and diversity of antigen-processing routes for respiratory syncytial virus cytotoxic T-lymphocyte epitopes.
Shifting immunodominance pattern of two cytotoxic T-lymphocyte epitopes in the F glycoprotein of the Long strain of respiratory syncytial virus.
Small molecules VP-14637 and JNJ-2408068 inhibit respiratory syncytial virus fusion by similar mechanisms.
Syncytium formation by recombinant vaccinia viruses carrying bovine parainfluenza 3 virus envelope protein genes.
The fusion glycoprotein of human respiratory syncytial virus facilitates virus attachment and infectivity via an interaction with cellular heparan sulfate.
The relative abundance of two measles virus fusion protein peptide-DR1 complexes expressed by B cells is independent of the form of the antigen.
Vesicular Stomatitis
Expression of RNA virus proteins by RNA polymerase II dependent expression plasmids is hindered at multiple steps.
Respiratory syncytial virus F envelope protein associates with lipid rafts without a requirement for other virus proteins.
The cytoplasmic tail of the human respiratory syncytial virus F protein plays critical roles in cellular localization of the F protein and infectious progeny production.
The surface glycoprotein E2 of bovine viral diarrhoea virus contains an intracellular localization signal.
The transmembrane domain sequence affects the structure and function of the newcastle disease virus fusion protein.
Viremia
Role of fusion protein cleavage site in the virulence of Newcastle disease virus.
Virus Diseases
A critical phenylalanine residue in the respiratory syncytial virus fusion protein cytoplasmic tail mediates assembly of internal viral proteins into viral filaments and particles.
A live attenuated human metapneumovirus vaccine strain provides complete protection against homologous viral infection and cross-protection against heterologous viral infection in BALB/c mice.
Analysis of a peptide inhibitor of paramyxovirus (NDV) fusion using biological assays, NMR, and molecular modeling.
Antigenic relevance of F protein in chronic hepatitis C virus infection.
Biological activity, binding site and affinity of monoclonal antibodies to the fusion protein of respiratory syncytial virus.
Characterization of the specific CD4+ T cell response against the F protein during chronic hepatitis C virus infection.
Characterization of two monoclonal antibodies, 38F10 and 44D11, against the major envelope fusion protein of Helicoverpa armigera nucleopolyhedrovirus.
Cleavage site of Newcastle disease virus determines viral fitness in persistent infection cells.
Genetic variability and circulation pattern of human metapneumovirus isolated in Italy over five epidemic seasons.
In vitro enhancement of respiratory syncytial virus infection of U937 cells by human sera.
Integrin ?v?1 Modulation Affects Subtype B Avian Metapneumovirus Fusion Protein-mediated Cell-Cell Fusion and Virus Infection.
Lactoferrin and surfactant protein A exhibit distinct binding specificity to F protein and differently modulate respiratory syncytial virus infection.
Macrolide antibiotics inhibit respiratory syncytial virus infection in human airway epithelial cells.
Manganese superoxide dismutase (MnSOD) and autoantibodies against MnSOD in acute viral infections.
Mutant forms of the F protein of human respiratory syncytial (RS) virus induce a cytotoxic T lymphocyte response but not a neutralizing antibody response and only transient resistance to RS virus infection.
Protection of mice against Sendai virus pneumonia by non-neutralizing anti-F monoclonal antibodies.
Respiratory syncytial virus activates epidermal growth factor receptor to suppress interferon regulatory factor 1-dependent interferon-lambda and antiviral defense in airway epithelium.
Soluble respiratory syncytial virus fusion protein in the fully cleaved, pretriggered state is triggered by exposure to low-molarity buffer.
The cytoplasmic tail of the human respiratory syncytial virus F protein plays critical roles in cellular localization of the F protein and infectious progeny production.
Xeroderma Pigmentosum
1-Methyl-4-phenyl-pyridinium time-dependently alters expressions of oxoguanine glycosylase 1 and xeroderma pigmentosum group F protein in PC12 cells.
Defining the function of xeroderma pigmentosum group F protein in psoralen interstrand cross-link-mediated DNA repair and mutagenesis.
Xeroderma pigmentosum group F protein binds to Eg5 and is required for proper mitosis: implications for XP-F and XFE.