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Information on EC 2.5.1.155 - phosphoglycerol geranylfarnesyltransferase

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EC Tree
IUBMB Comments
The enzyme, characterized from the archaeon Aeropyrum pernix, catalyses the first pathway-specific step in the biosynthesis of the core membrane C25,C25-diether lipids in some archaea. It does not act on geranylgeranyl diphosphate. cf. EC 2.5.1.41, phosphoglycerol geranylgeranyltransferase.
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The expected taxonomic range for this enzyme is: Aeropyrum pernix
Synonyms
APE_0621, geranylfarnesylglyceryl phosphate synthase, GFGP synthase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
all-trans-pentaprenyl diphosphate + sn-glycerol 1-phosphate = sn-3-O-(farnesylgeranyl)glycerol 1-phosphate + diphosphate
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PATHWAY SOURCE
PATHWAYS
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