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Disease on EC 3.4.21.4 - trypsin

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Abdominal Abscess
Prevention of intra-abdominal abscesses with fibrinolytic agents.
Abruptio Placentae
Trophoblastic apoptosis in mice with preterm delivery and its suppression by urinary trypsin inhibitor.
Abscess
Prevention of intra-abdominal abscesses with fibrinolytic agents.
[Studies on efficiency of the digestive enzyme trypsin in inflammations and abscess formation in tooth, mouth and jaw region with special reference to administration in root canal therapy]
Acantholysis
Action of trypsin on human plantar stratum corneum. An ultrastructural study.
Anti-cell surface pemphigus autoantibody stimulates plasminogen activator activity of human epidermal cells. A mechanism for the loss of epidermal cohesion and blister formation.
Corticosteroids, aurothioglucose and soybean trypsin inhibitor do not prevent pemphigus antibody-induced acantholysis in vitro.
Effects of trypsin on the cyclic AMP system of the pig skin.
The pathogenic role of pemphigus antibodies and proteinase in epidermal acantholysis.
Acidosis, Lactic
Application of molecular imaging combined with genetic screening in diagnosing MELAS, diabetes and recurrent pancreatitis.
Acne Vulgaris
The effects of trypsin on apoptosis, utriculi size, and skin elasticity in the Rhino mouse.
Acquired Immunodeficiency Syndrome
A quantitative and cartographic study of retinal microvasculopathy in acquired immunodeficiency syndrome.
CATIONIC TRYPSIN: A PREDOMINANT PROTEINASE IN PACIFIC SAURY (COLOLABIS SAIRA) PYLORIC CECA
Role of HIV and CMV in the pathogenesis of retinitis and retinal vasculopathy in AIDS patients.
Serum pancreatic enzymes in HIV-seropositive patients.
Stability of tuna trypsin-loaded alginate-chitosan beads in acidic stomach fluid and the release of active enzyme in a simulated intestinal tract environment.
Trypsin and chymotrypsin as aids in the diagnosis of pancreatic disease.
Trypsin inhibition: a potential cause of cobalamin deficiency common to the pathogenesis of Alzheimer-type dementia and AIDS dementia complex?
Acute Coronary Syndrome
Expression of ectopic trypsin in atherosclerotic plaques and the effects of aprotinin on plaque stability.
Acute Kidney Injury
Beneficial effects of the urinary trypsin inhibitor urinastatin on renal insults induced by gentamicin and mercuric chloride (HgCl2) poisoning.
Elevated pancreatic secretory trypsin inhibitor levels during severe inflammatory disease, renal insufficiency, and after various surgical procedures.
Evaluation of podocin in urine in horses using qualitative and quantitative methods.
Evidence for the participation of proteases on protein catabolism during hypercatabolic renal failure.
Plasma levels of pancreatic secretory trypsin inhibitor in relation to amylase and lipase in patients with acute and chronic renal failure.
Rapid accumulation of plasma acid-stable trypsin inhibitor in experimental acute renal injury.
Renal microcirculation in experimental acute pancreatitis of dogs.
[Therapeutic effects and influence on the urinary enzyme activity of human urinary trypsin inhibitor (urinastatin) in cases with acute renal failure--changes in the urinary activities of NAG and AAP]
[Trypsin inhibitor fractions in the urine in acute renal failure]
Acute Lung Injury
Antioxidative role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide.
Does Urinary Trypsin Inhibitor Have a Role in Acute Lung Injury Induced by Pulmonary Contusion: A Basic Research in a Model of Rats.
Effect of Ulinastatin, a human urinary trypsin inhibitor, on the oleic acid-induced acute lung injury in rats via the inhibition of activated leukocytes.
Effects of Urinary Trypsin Inhibitor on Lipopolysaccharide-Induced Acute Lung Injury in Rabbits.
Lidocaine attenuates acute lung injury induced by a combination of phospholipase A2 and trypsin.
Protective role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide.
Up-regulation of trypsin and mesenchymal MMP-8 during development of hyperoxic lung injury in the rat.
Urinary Trypsin Inhibitor Attenuates Acute Lung Injury by Improving Endothelial Progenitor Cells Functions.
Urinary trypsin inhibitor attenuates lipopolysaccharide-induced acute lung injury by blocking the activation of p38 mitogen-activated protein kinase.
Urinary Trypsin Inhibitor Attenuates Seawater-Induced Acute Lung Injury by Influencing the Activities of Nuclear Factor-?B and Its Related Inflammatory Mediators.
Adenocarcinoma
A glycopeptide from adenocarcinoma tissue of human lung.
A tumor-suppressive role for trypsin in human cancer progression.
Action of dietary trypsin, pressed coffee oil, silymarin and iron salt on 1,2-dimethylhydrazine tumorigenesis by gavage.
Autocrine extra-pancreatic trypsin 3 secretion promotes cell proliferation and survival in esophageal adenocarcinoma.
Characterization of novel genetic alterations in salivary gland secretory carcinoma.
Co-expression of trypsin and tumour-associated trypsin inhibitor (TATI) in colorectal adenocarcinomas.
Demonstration of pancreatic secretory trypsin inhibitor in serum-free culture medium conditioned by the human pancreatic carcinoma cell line CAPAN-1.
Effects of trypsin on binding of insulin and concanavalin A and on glucose and proline transport in the R3230AC mammary adenocarcinoma.
Enhanced invasiveness of pancreatic adenocarcinoma cells stably transfected with cationic trypsinogen cDNA.
Expression of gelatinase A, tissue inhibitor of metalloproteinases-2, matrilysin, and trypsin(ogen) in lung neoplasms: an immunohistochemical study.
Expression of pancreatic secretory trypsin inhibitor gene in human colorectal tumor.
Identification of one- and two-chain forms of trypsinogen 1 produced by a human gastric adenocarcinoma cell line.
Immunohistochemical analysis of pancreatic secretory trypsin inhibitor expression in pulmonary adenocarcinoma: its possible participation in scar formation of the tumor tissues.
Neutral proteinases and inhibitors secreted by human rectal adenocarcinoma cell line (RCM-1).
New human colorectal carcinoma cell lines that secrete proteinase inhibitors in vitro.
Overexpression of pancreatic secretory trypsin inhibitor in pancreatic cancer. Evaluation of its biological function as a growth factor.
Pancreatic secretory trypsin inhibitor immunoreactivity detected in serum-free culture medium of human pancreatic carcinoma cell line, CAPAN-1.
Plasma trypsin in chronic pancreatitis and pancreatic adenocarcinoma.
Production and characterization of monoclonal antibody to a 60-kD glycoprotein in ovarian carcinoma.
Protease Inhibitors Protect Bovine Colostrum or Chicken Egg Growth Factors from Pancreatic Enzyme Digestion in AGS Cells or Colitic Rats.
Rhizoma Pinelliae trypsin inhibitor separation, purification and inhibitory activity on the proliferation of BGC-823 gastric adenocarcinoma cells.
Secretion of protease nexin-II/amyloid beta protein precursor by human colorectal carcinoma cells and its modulation by cytokines/growth factors and proteinase inhibitors.
Separation of induction and expression of tight junction formation mediated by proteinases.
Simplified methods for obtaining purified oocysts from mice and for growing Cryptosporidium parvum in vitro.
The prevalence of pancreatic acinar differentiation in gastric adenocarcinoma: report of a case and immunohistochemical study of 111 additional cases.
Tumor markers CA 125, carcinoembryonic antigen and tumor-associated trypsin inhibitor in patients with cervical adenocarcinoma.
[Characteristics of the kallikreins in healthy and malignant (adenocarcinoma) mucous membrane of the human large intestine]
[Hereditary pancreatitis - a clinically relevant cause of pancreatic adenocarcinoma?]
[Preparation of tumor cells from human lung cancer tissue for the purpose of cloning]
[The effects of epidermal growth factor and its antibody on the growth of xenografts in athymic nude mice]
Adenocarcinoma of Lung
A novel developmentally regulated gene in lung mesenchyme: homology to a tumor-derived trypsin inhibitor.
Investigation on conformational variation and activity of trypsin affected by black phosphorus quantum dots via multi-spectroscopy and molecular modeling.
Lung adenocarcinoma-related TNF-?-dependent inflammation upregulates MHC-II on alveolar type II cells through CXCR-2 to contribute to Treg expansion.
Protease-activated receptor (PAR)-1 and PAR-2 participate in the cell growth of alveolar capillary endothelium in primary lung adenocarcinomas.
Adenocarcinoma, Follicular
Monitoring of brightness temperature of suspension of follicular thyroid carcinoma cells in SHF range by radiothermometry.
Adenoma
A trail of research revisted.
Adrenocortical carcinoma. An immunohistochemical comparison with renal cell carcinoma.
Correlation between nucleolar organizer regions and cell proliferation in pancreatic acinar cell proliferative lesions in rats.
Effect of long-term feeding of soy-based diets on the pancreas of Cebus monkeys.
Expression of matrix metalloproteinases and related tissue inhibitors in the cyst fluids of ovarian mucinous neoplasms.
Expression of pancreatic secretory trypsin inhibitor gene in human colorectal tumor.
Residue trypsin inhibitor: data needs for risk assessment.
Transmembrane orientation of palmitoyl-CoA: lysophosphatidylcholine acyltransferase in microsomes isolated from an alveolar type II cell adenoma and rat liver.
[Endocrinological characteristic of primary hyperparathyroidism]
Adenomatous Polyposis Coli
Familial pancreatic carcinoma in Jews.
Spiking of serum specimens with exogenous reporter peptides for mass spectrometry based protease profiling as diagnostic tool.
Adrenal Hyperplasia, Congenital
[Screening for hereditary diseases. What other screening?]
Adrenocortical Carcinoma
Adrenocortical carcinoma. An immunohistochemical comparison with renal cell carcinoma.
Adrenocortical Hyperfunction
[Immunoreactive trypsin in the blood of patients with functional disorders of the adrenal cortex]
[Immunoreactive trypsin in the blood serum of patients with endogenous hypercorticism]
AIDS-Related Complex
Serum pancreatic enzymes in HIV-seropositive patients.
Alagille Syndrome
Th-17 cells infiltrate the liver in human biliary atresia and are related to surgical outcome.
Albuminuria
Diagnosis of albuminuria by tryptic digestion and matrix-assisted laser desorption ionization/time-of-flight mass spectrometry.
Alkalosis
[Trypsin inhibitor activity in the colostrum of cows]
alpha 1-Antitrypsin Deficiency
Chronic pancreatitis with alpha 1-antitrypsin deficiency: from uncontrolled trypsin activation?
Liver disease in alpha-1-antitrypsin deficiency: prognostic indicators.
Pi-Z phenotypes in a pulmonary clinic. Their prevalence and physiologic state.
Alzheimer Disease
Alzheimer dementia and Pick's disease: neurofibrillary tangles and Pick bodies are associated with identical phosphorylated neurofilament epitopes.
Alzheimer's disease amyloid peptide is encoded by two exons and shows similarity to soybean trypsin inhibitor.
Anoxia leads to a rapid translocation of human trypsinogen 4 to the plasma membrane of cultured astrocytes.
Dietary Wheat Amylase Trypsin Inhibitors Impact Alzheimer's Disease Pathology in 5xFAD Model Mice.
Does the Kunitz domain from the Alzheimer's amyloid beta protein precursor inhibit a kallikrein responsible for post-translational processing of nerve growth factor precursor?
Evolutionary origin of a Kunitz-type trypsin inhibitor domain inserted in the amyloid beta precursor protein of Alzheimer's disease.
Fibrillar amyloid beta-protein inhibits the activity of high molecular weight brain protease and trypsin.
Identification of sustainable trypsin active-site inhibitors from Nigrospora sphaerica strain AVA-1.
Kunitz-type protease inhibitor found in rat mast cells. Purification, properties, and amino acid sequence.
Structural features of the Abeta amyloid fibril elucidated by limited proteolysis.
Synthesis of new 3-alkoxy-7-amino-4-chloro-isocoumarin derivatives as new beta-amyloid peptide production inhibitors and their activities on various classes of protease.
Trypsin inhibitor activities of fibroblasts increase with age of donor and are unaltered in familial Alzheimer's disease.
Trypsin interaction with the senile plaques of Alzheimer disease is mediated by beta-protein precursor.
Amyloidosis
Characterization of two highly amyloidogenic mutants of transthyretin.
Generalized amyloidosis: a rare complication of cystic fibrosis.
On-a-chip tryptic digestion of transthyretin: a step toward an integrated microfluidic system for the follow-up of familial transthyretin amyloidosis.
Anaphylaxis
ANAPHYLACTIC REACTION TO TRYPSIN.
Immunogenicity of hapten-carrier conjugates associated with liposomes.
Kunitz soybean trypsin inhibitor: a specific allergen in food anaphylaxis.
The release of four mediators of immediate hypersensitivity from human leukemic basophils.
Urinary trypsin inhibitor improves peripheral microcirculation and bronchospasm associated with systemic anaphylaxis in rabbits in vivo.
[A case of anaphylactic reaction to trypsin]
[Anaphylactoid reaction to trypsin following local administration of Dontisolon ointment]
[Changes in serum activity of trypsin in patients with bronchial asthma between attacks and during experimental anaphylactic shock]
[Trypsin, fibrinolysis and anaphylactic shock in the rabbit.]
Anemia
Physicochemical studies of equine infectious anemia virus. II. Sensitivity of the virus to trypsin.
Reversible staining and peptide mapping of proteins transferred to nitrocellulose after separation by sodium dodecylsulfate-polyacrylamide gel electrophoresis.
Anemia, Hemolytic
Electrophoretic demonstration of heterozygosis in hereditary pyruvate kinase deficiency. An unusual method.
Anemia, Sickle Cell
Newborn screening for sickle cell disorders using tandem mass spectrometry: three years' experience of using a protocol to detect only the disease states.
Serum trypsin inhibitory capacity in sickle cell disease.
Aneurysm
A histopathologic study of retinal arterial aneurysms.
Angina, Unstable
ITIH4 serum concentration increases during acute-phase processes in human patients and is up-regulated by interleukin-6 in hepatocarcinoma HepG2 cells.
Anthrax
Adenylate cyclase toxins from Bacillus anthracis and Bordetella pertussis. Different processes for interaction with and entry into target cells.
Using molecular docking, 3D-QSAR, and cluster analysis for screening structurally diverse data sets of pharmacological interest.
Appendicitis
[The activity of trypsin and proteolytic inhibitors in complicated forms of appendicitis in children]
Arteriosclerosis
[STUDIES ON TRYPSIN INHIBITOR AND ANTIPLASMIN IN HUMAN SERUM. II. ON VARIOUS DISEASES EXCEPT ARTERIOSCLEROSIS.]
Arthritis
6-sulphanilamidoindazole arthritis of rats: relation between acute-phase proteins, degree of arthritis and treatment with soybean trypsin inhibitor.
Analgesic and anti-edematogenic effects of oral trypsin were abolished after subdiaphragmatic vagotomy and spinal monoaminergic inhibition in rats.
Antinociceptive and anti-rheumatoidal effects of Kalopanax pictus extract and its saponin components in experimental animals.
Experimental arthritis induced by granulocyte collagenase.
Leech thrombin inhibitors.
Pancreatic carcinoma with polyarthritis, fat necrosis, and high serum lipase and trypsin activity.
Suppression of streptococcal cell wall-induced arthritis by a potent protease inhibitor, bis(5-amidino-2-benzimidazolyl)methane.
Arthritis, Experimental
Inhibitory effect of enzyme therapy and combination therapy with cyclosporin A on collagen-induced arthritis.
Arthritis, Infectious
[Value of the assay of protein SAA and urinary antitrypsin activity in osteoarticular infections]
Arthritis, Rheumatoid
Identification of sustainable trypsin active-site inhibitors from Nigrospora sphaerica strain AVA-1.
Impaired activity of protease inhibitors towards neutrophil elastase bound to human articular cartilage.
Prevention of murine EAE by oral hydrolytic enzyme treatment.
Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system.
The use of trypsin in rheumatoid arthritis: a clinical study.
Trypsin-2 degrades human type II collagen and is expressed and activated in mesenchymally transformed rheumatoid arthritis synovitis tissue.
Ascariasis
[Trypsin and alpha-amylase activity in the pancreas of guinea pigs. V. Effects of administration of vitamin A and B 2 during the larval stage of ascariasis]
Asthma
A study of the binding of immunoglobulin G and immunoglobulin E from children with bronchial asthma to peptides derived from group II antigen of Dermatophagoides pteronyssinus.
Alfa 1 antitrypsin and protease levels in Puerto Rican asthmatics: a pilot study.
Comparison of three methods for the determination of serum alpha-1-antitrypsin in patients with pulmonary diseases.
Exposure levels of asthmatic children to allergens, endotoxins, and serine proteases in a tropical environment.
Expression and function of proteinase-activated receptor 2 in human bronchial smooth muscle.
Genetic architecture underlying the expression of eight ?-amylase trypsin inhibitors.
Genome mapping of seed-borne allergens and immunoresponsive proteins in wheat.
IgE mediated hypersensitivity to pancreatic extract (PE) in parents of cystic fibrosis (CF) children.
Increased serum concentration of urinary trypsin inhibitor with asthma exacerbation.
Preliminary studies on the effect of rebamipide against the trypsin and egg-albumin induced experimental model of asthma.
Protease-activated receptor-2 signaling through ?-arrestin-2 mediates Alternaria alkaline serine protease-induced airway inflammation.
Protease-activated receptor-2-mediated Ca2+ signaling in guinea pig tracheal epithelial cells.
Role of estrogen receptor- ? in an experimental model of bronchial asthma.
Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system.
The use of tryptar (trypsin) in bronchial asthma and other respiratory conditions.
Trypsin binding activity of alpha 2-macroglobulin in cystic fibrosis and other lung diseases.
[Changes in serum activity of trypsin in patients with bronchial asthma between attacks and during experimental anaphylactic shock]
[Death during trypsin inhalation by an asthma patient under prolonged corticosteroid therapy]
[Diagnostic value of using a 2.5 per cent solution of trypsin in pulmonary tuberculosis and chronic pneumonia in combination with bronchial asthma]
[Immunotherapy effect of ploypeptide vaccine of allergen group 1 from Dermatophagoides farinae on asthma mice].
Asthma, Occupational
Immediate hypersensitivity to hog trypsin resulting from industrial exposure.
Astrocytoma
Activity of recombinant trypsin isoforms on human proteinase-activated receptors (PAR): mesotrypsin cannot activate epithelial PAR-1, -2, but weakly activates brain PAR-1.
Mesotrypsin, a brain trypsin, activates selectively proteinase-activated receptor-1, but not proteinase-activated receptor-2, in rat astrocytes.
Production of amyloid beta protein precursor as a proteinase inhibitor by human astrocytic tumors.
The presence of distinct soluble and particulate trypsin inhibitors in human astrocytoma tissue.
The two-receptor system PAR-1/PAR-4 mediates alpha-thrombin-induced [Ca(2+)](i) mobilization in human astrocytoma cells.
Ataxia Telangiectasia
Familial pancreatic carcinoma in Jews.
Atherosclerosis
Carotid atherosclerotic plaques: proteomics study after a low-abundance protein enrichment step.
Expression of ectopic trypsin in atherosclerotic plaques and the effects of aprotinin on plaque stability.
[Improvements in the technical conditions for the evaluation of an elastolytic activity. The role of tryspin as an activator (author's transl)]
Autoimmune Diseases
In vitro study on the immunological effect of bromelain and trypsin on mononuclear cells from humans.
Prevention of murine EAE by oral hydrolytic enzyme treatment.
Versican-A Critical Extracellular Matrix Regulator of Immunity and Inflammation.
Autoimmune Pancreatitis
Identification of a novel autoantibody against pancreatic secretory trypsin inhibitor in patients with autoimmune pancreatitis.
Bacteremia
Haemophilus influenzae b bacteremia and meningitis in infant rabbits after intranasal inoculation.
Hemophilus influenzae type b meningitis in infant rabbits. Pathogenesis and therapy.
Bacterial Infections
Determination of urinary trypsin inhibitor provides insight into postoperative complications in patients following esophagectomy.
JcTI-I: a novel trypsin inhibitor from Jatropha curcas seed cake with potential for bacterial infection treatment.
Urinary trypsin inhibitory activity for the diagnosis of bacterial infection: a prospective study in 690 patients.
Urinary trypsin inhibitory activity: not a useful test for detecting bacterial infections in elderly people.
[Large recombinant protein displayed on filamentous phage surface and its interaction with small molecule]
beta-Thalassemia
Serum immunoreactive trypsin in beta-thalassaemia major.
Bile Reflux
Bile acids and trypsin are unimportant in alkaline esophageal reflux.
The key event of acute pancreatitis: pancreatic duct obstruction and bile reflux, not a single one can be omitted.
Biliary Atresia
[Levels of serum immunoreactive trypsin in children with intra- and extrahepatic cholestasis]
Biliary Fistula
Rat pancreatic response to intestinal infusion of intact and hydrolyzed protein.
Biliary Tract Diseases
[Analysis of trypsin inhibitor level and its fluctuation in pancreatic and biliary tract diseases]
Biliary Tract Neoplasms
Time-resolved immunofluorometric assay of trypsin-1 complexed with alpha(1)-antitrypsin in serum: increased immunoreactivity in patients with biliary tract cancer.
Blister
Comparative responses of normal and malignant mouse mammary cells to modulation of surface properties.
Conversion of blebs to microvilli: cell surface reorganisation after trypsin.
Decreased specific anti-elastase activity in the uninvolved skin of patients with psoriasis.
Dissociation of suction blister roof epidermis with trypsin and desoxyribonuclease into viable single cells.
Enriched epidermal Langerhans cells are potent antigen-presenting cells for T cells.
On the flexibility of surface structures of tumor cells in vitro.
Origin and properties of the blister formation factor in blister fluids from recessive dystrophic epidermolysis bullosa.
Pemphigus serum-induced loss of microvilli from human epidermal cells.
Proteases are responsible for blister formation in recessive dystrophic epidermolysis bullosa and epidermolysis bullosa simplex.
Rounding and steroidogenesis of enzyme- and ACTH-treated Y-l mouse adrenal tumor cells.
Studies on human epidermal Langerhans cells III. Induction of T lymphocyte response to nickel sulphate in sensitized individuals.
Studies on human epidermal Langerhans cells. I. Allo-activating and antigen-presenting capacity.
Studies on human epidermal Langerhans' cells: II. Activation of human T lymphocytes to herpes simplex virus.
[Bullous mastocytosis in a child]
[Quantitative measurements on tryptic degradation of lactate dehydrogenase in human serum, skin blister fluid and sperm. A contribution to the problem of trypsin inhibitor.]
[Study of cantharides blister fluid in the analysis of the mechanism of action of trypsin in the treatment of chronic peripheral arterial diseases.]
Bluetongue
Effects of proteolytic enzymes on the infectivity, haemagglutinating activity and protein composition of bluetongue virus type 20.
Sensitivity of bluetongue virus to lipid solvents, trypsin and pH changes and its serological relationship to arboviruses.
Bone Diseases
Tumor-associated trypsin inhibitor (TATI) in bone diseases.
Brain Contusion
Significant elevation of urinary trypsin inhibitor in patients with brain contusion - a preliminary report.
Brain Death
Protective effects of urinary trypsin inhibitor (UTI) on hepatic microvasculature in hypotensive brain-dead rats.
Brain Diseases
Identification of trypsin I as a candidate for influenza A virus and Sendai virus envelope glycoprotein processing protease in rat brain.
Raised serum immunoreactive trypsin in the haemorrhagic shock and encephalopathy syndrome.
[Probable pancreatic encephalopathy treated by trypsin inhibitors]
Brain Edema
The role of bradykinin in mediating ischemic brain edema in rats.
[Effect of trypsin inhibitor on cerebral edema associated with cerebrovascular diseases]
[Studies on the involvement of bradykinin in the formation of ischemic brain edema]
Brain Injuries
Osteopontin Is a Blood Biomarker for Microglial Activation and Brain Injury in Experimental Hypoxic-Ischemic Encephalopathy.
The Protective Roles of Urinary Trypsin Inhibitor in Brain Injury Following Fat Embolism Syndrome in a Rat Model.
Brain Neoplasms
cDNA cloning of a novel trypsin inhibitor with similarity to pathogenesis-related proteins, and its frequent expression in human brain cancer cells.
Glioblastoma Stem Cells and Comparison of Isolation Methods.
Pretreatment with protease is a useful experimental strategy for enhancing adenovirus-mediated cancer gene therapy.
Breast Neoplasms
A novel discriminant score based on tumor-associated trypsin inhibitor for accurate diagnosis of metastasis in patients with breast cancer.
A novel trypsin-like enzyme in breast cancer.
A thermostable trypsin inhibitor with antiproliferative activity from small pinto beans.
Binding of transferrin to membrane-associated proteoglycans in breast-cancer cells.
Brown Kidney Bean Bowman-Birk Trypsin Inhibitor is Heat and pH Stable and Exhibits Anti-proliferative Activity.
Cbl-b accelerates trypsin-induced cell detachment through ubiquitination and degradation of proline-rich tyrosine kinase 2.
Cbl-b promotes cell detachment via ubiquitination of focal adhesion kinase.
Characterization and microarray analysis of genes in human lymphatic endothelial cells from patients with breast cancer.
Co-Expression of a Chimeric Protease Inhibitor Secreted by a Tumor-Targeted Salmonella Protects Therapeutic Proteins from Proteolytic Degradation.
Constitutive protease-activated receptor-2-mediated migration of MDA MB-231 breast cancer cells requires both beta-arrestin-1 and -2.
CUX1 transcription factor is a downstream effector of the proteinase-activated receptor 2 (PAR2).
Early diagnostic protein biomarkers for breast cancer: how far have we come?
Enhanced killing of breast cancer cells by a d-amino acid analog of the winter flounder-derived pleurocidin NRC-03.
Increase in the estrogen binding capacity of breast cancer cytosols following limited proteolysis with trypsin.
MALDI-TOF mass spectrometry analysis of cerebrospinal fluid tryptic peptide profiles to diagnose leptomeningeal metastases in patients with breast cancer.
Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109.
Non-receptor tyrosine kinase 2 reaches its lowest expression levels in human breast cancer during regional nodal metastasis.
Proteinase-activated receptor-2 expression in breast cancer and the role of trypsin on growth and metabolism of breast cancer cell line MDA MB-231.
Purification and identification of a 28-kDa calcium-regulated heat-stable protein. A novel secretagogue-regulated phosphoprotein in exocrine pancreas.
Searching for early breast cancer biomarkers by serum protein profiling of pre-diagnostic serum; a nested case-control study.
Serum degradome markers for the detection of breast cancer.
Serum proteomic biomarker discovery reflective of stage and obesity in breast cancer patients.
Serum tumour markers CA 15-3, TPA, TPS, hCGbeta and TATI in the monitoring of chemotherapy response in metastatic breast cancer.
Steroid sequestration and tightly bound oestrogen-protein complexes in human breast tumours and a breast cancer cell line.
The cyclic cystine knot miniprotein MCoTI-II is internalized into cells by macropinocytosis.
The P2' residue is a key determinant of mesotrypsin specificity: Engineering a high affinity inhibitor with anticancer activity.
Urinary cancer-related protein EDC1 and serum inter-alpha trypsin inhibitor in breast cancer.
Bronchial Diseases
[Significance of enzyme therapy with oral trypsin and chymotrypsin in chronic bronchial diseases in the course of inhalatory balneotherapy and of pulmonary ventilation]
[Use of combined trypsin and antibiotics in inhalation therapy of some bronchial diseases.]
Bronchial Spasm
Pharmacological Evaluation of Antiasthmatic Activity of Myrica nagi Bark Extracts.
Urinary trypsin inhibitor improves peripheral microcirculation and bronchospasm associated with systemic anaphylaxis in rabbits in vivo.
Bronchiolitis
Neutrophil-mediated inflammation in respiratory syncytial viral bronchiolitis.
Bronchitis
Comparison of three methods for the determination of serum alpha-1-antitrypsin in patients with pulmonary diseases.
Effect of different passage histories of infectious bronchitis virus on the sensitivity to inhibitors in chick serum and their removal by trypsin.
In vitro cultivation of cells from the chorioallantoic membrane of chick embryos.
Plaque formation by avian infectious bronchitis virus in primary chick embryo fibroblast cells in the presence of trypsin.
Treatment of asthmatic bronchitis with drugs, administered as an aerosol; the profit of pneumotachography in judging its merits, trypsin a powerful new drug.
Treatment with Exogenous Trypsin Expands In Vitro Cellular Tropism of the Avian Coronavirus Infectious Bronchitis Virus.
[Prospects of etiological diagnosis of bronchitis]
[Replication characteristics and cytopathic effect of southern German field isolates of chicken infectious bronchitis virus in cell cultures and the effect of trypsin]
[Therapy with hormonal preparations and trypsin of a patient with plastic bronchitis]
Bronchitis, Chronic
The effect of intramuscular trypsin in chronic bronchitis.
[Chronic bronchitis and trypsin inhibitors]
[Effectiveness of trypsin electrophoresis in treating chronic bronchitis]
[Inhalation treatment of chronic bronchitis with trypsin.]
Bronchopulmonary Dysplasia
Limited fat digestion in infants with bronchopulmonary dysplasia.
Pulmonary trypsin-2 in the development of bronchopulmonary dysplasia in preterm infants.
Serial trypsin inhibitory capacity and ceruloplasmin levels in prematures at risk for bronchopulmonary dysplasia.
Burkitt Lymphoma
Patterns of immunoglobulin staining in paraffin-embedded malignant lymphomas.
Calciphylaxis
[STUDIES ON THE EFFECTS OF A TRYPSIN INHIBITOR (TRASYLOL) ON ENZYME ACTIVITIES AND MORPHOLOGY IN TAUROCHOLATE AND CALCIPHYLAXIS PANCREATITIS OF THE RAT (A CONTRIBUTION TO THE PATHOGENESIS OF PANCREATITIS. II.)]
Candidiasis
Cell preparation method with trypsin digestion for counting of colony forming units in Candida albicans-infected mucosal tissues.
Candidiasis, Oral
Cell preparation method with trypsin digestion for counting of colony forming units in Candida albicans-infected mucosal tissues.
Carcinogenesis
Action of dietary trypsin, pressed coffee oil, silymarin and iron salt on 1,2-dimethylhydrazine tumorigenesis by gavage.
Aflatoxin G1-induced oxidative stress causes DNA damage and triggers apoptosis through MAPK signaling pathway in A549 cells.
Alcohol and pancreatic cancer.
Blocking effects of synthetic trypsin inhibitor (camostat) on pancreatic carcinogenesis in hamsters initiated with N-nitrosobis(2-oxopropyl)amine.
Blood serum alpha fetoprotein enhancer binding protein, a tumor suppressor, decreases in chronic HBV hepatitis patients as hepatocellular cancer appears.
Bowman-Birk inhibitor abates proteasome function and suppresses the proliferation of MCF7 breast cancer cells through accumulation of MAP kinase phosphatase-1.
Early indicators of exocrine pancreas carcinogenesis produced by non-genotoxic agents.
Effects of dietary soya bean trypsin inhibitor concentrate on initiation and growth of putative preneoplastic lesions in the pancreas of the rat.
Experimental pancreatic cancer: role of species, sex and diet.
Impairment of alveolar type-II cells involved in the toxicity of Aflatoxin G(1) in rat lung.
Inhibition of oral carcinogenesis by a protease inhibitor.
Inhibitory effects of crude soybean trypsin inhibitor on pancreatic ductal carcinogenesis in hamsters after initiation with N-nitrosobis(2-oxopropyl)amine.
Inhibitory effects of soybean trypsin inhibitor during initiation and promotion phases of N-nitrosobis(2-oxopropyl)amine-induced hamster pancreatic carcinogenesis.
Inhibitory effects of soybean trypsin inhibitor on induction of pancreatic neoplastic lesions in hamsters by N-nitrosobis(2-oxopropyl)amine.
Is There a Trojan Horse to Aggressive Pancreatic Cancer Biology? A Review of the Trypsin-PAR2 Axis to Proliferation, Early Invasion, and Metastasis.
Lung adenocarcinoma-related TNF-?-dependent inflammation upregulates MHC-II on alveolar type II cells through CXCR-2 to contribute to Treg expansion.
Marginal zinc status does not exacerbate pancreatic carcinogenesis associated with dietary soybean trypsin inhibitor concentrate in rats.
Potent chemopreventive agents against pancreatic cancer.
Prostate adenocarcinoma and COVID-19: The possible impacts of TMPRSS2 expressions in susceptibility to SARS-CoV-2.
Protease-activating-receptor-2 is frequently expressed in papillary adenocarcinoma of the gallbladder.
Serine protease inhibitor Kazal type 1 (SPINK1) as a prognostic marker in stage IV colon cancer patients receiving cetuximab based targeted therapy.
Serine Protease Inhibitor Kazal Type 1 (SPINK1) Promotes Proliferation of Colorectal Cancer Through the Epidermal Growth Factor as a Prognostic Marker.
Stimulation of the growth of azaserine-induced nodules in the rat pancreas by dietary camostate (FOY-305).
Suppression of 3-methylcholanthrene-induced cellular transformation by timed administration of the Bowman-Birk protease inhibitor.
The effects on cellular functions of bile acid and trypsin in stagnant bile juice in anomalous arrangement of the pancreaticobiliary duct.
Trypsin in colorectal cancer: molecular biological mechanisms of proliferation, invasion, and metastasis.
Tumor-associated trypsin inhibitor (TATI) and tumor-associated trypsin-2 (TAT-2) predict outcomes in gastric cancer.
[Effect of synthetic protease inhibitor on the oncogenesis of pancreatic cancer in hamsters: study on pancreatic endocrine cells and free radicals]
Carcinoid Tumor
[Preparation of tumor cells from human lung cancer tissue for the purpose of cloning]
Carcinoma
A comparative evaluation of the ability of serum CA 125, CA 19-9, CA 15-3, CA 50, CA 72-4 and TATI assays in reflecting the course of disease in patients with ovarian carcinoma.
A direct cytogenetic technique for mouse skin carcinomas and papillomas.
A homogeneous cellular histone deacetylase assay suitable for compound profiling and robotic screening.
A tumor-suppressive role for trypsin in human cancer progression.
Acid stable protease inhibitor in ascites of ovarian carcinoma.
Acid stable trypsin inhibitor in bile.
Acinar cell carcinoma of the pancreas metastatic to the ovary: a report of 4 cases.
Acinar-islet cell carcinoma presenting as insulinoma.
Actin-dependent tumour cell adhesion after short-term exposure to the antimetastasis ruthenium complex NAMI-A.
Analyte-activable probe for protease based on cytochrome C-capped Mn: ZnS quantum dots.
Anti-metastatic therapy by urinary trypsin inhibitor in combination with an anti-cancer agent.
Assessment of the tumor-associated trypsin inhibitor (TATI) marker in patients with carcinoma of the uterine body 17 years after treatment.
Association of trypsin expression with recurrence and poor prognosis in human esophageal squamous cell carcinoma.
Association of trypsin expression with tumour progression and matrilysin expression in human colorectal cancer.
Association of tumor-associated trypsin inhibitor (TATI) expression with molecular markers, pathologic features and clinical outcomes of urothelial carcinoma of the urinary bladder.
Autocrine induction of invasion and metastasis by tumor-associated trypsin inhibitor in human colon cancer cells.
Bcl-10, trypsin and synaptophysin helps recognize acinar cell and mixed acinar neuroendocrine cell carcinoma of the pancreas on both preoperative cytological samples and needle biopsy specimens.
Changes in IL-6, IL-8, C-reactive protein and pancreatic secretory trypsin inhibitor after transcatheter arterial chemo-embolization therapy for hepato-cellular carcinoma.
Characterisation of changes in the proteome in different regions of 3D multicell tumor spheroids.
Characterization of structural domains of the human epidermal growth factor receptor obtained by partial proteolysis.
Chemotherapy as initial treatment for cervical carcinoma: clinical and tumor marker response.
Clinicopathologic study of 62 acinar cell carcinomas of the pancreas: insights into the morphology and immunophenotype and search for prognostic markers.
Co-expression of trypsin and tumour-associated trypsin inhibitor (TATI) in colorectal adenocarcinomas.
Coagulative and fibrinolytic properties of ascitic fluid associated with ovarian tumors.
Comparative study of the novel RGD motif-containing ITG?v?6 binding peptides SFLAP3 and SFITGv6 for diagnostic application in HNSCC.
Concentrations of protease and anti-protease in serum of patients with pancreatic cancer.
Control of tumor growth in animals by infusion of an angiogenesis inhibitor.
Cytokeratin 8-MHC class I interactions: a potential novel immune escape phenotype by a lymph node metastatic carcinoma cell line.
Demonstration of pancreatic secretory trypsin inhibitor in serum-free culture medium conditioned by the human pancreatic carcinoma cell line CAPAN-1.
Development of ionic strength/pH/enzyme triple-responsive zwitterionic hydrogel of the mixed l-glutamic acid and l-lysine polypeptide for site-specific drug delivery.
Differential expression of trypsin in human ovarian carcinomas and low-malignant-potential tumors.
Differential expression of trypsinogen and tumor-associated trypsin inhibitor (TATI) in bladder cancer.
Disaggregation studies of xenograft solid tumors grown from pure or admixed clonal subpopulations from a heterogeneous human colon adenocarcinoma.
Effect of bombesin administration on serum immunoreactive trypsin in patients with pancreatic carcinoma.
Effect of enzymic removal of cell surface constituents on metastatic colonisation potential of mouse mammary tumour cells.
Effect of secretin stimulation upon serum immunoreactive trypsin in patients with carcinoma of the pancreas.
Egg lectin of Rana japonica and its receptor glycoprotein of Ehrlich tumor cells.
Enhanced invasiveness of pancreatic adenocarcinoma cells stably transfected with cationic trypsinogen cDNA.
Enhancement of mechanisms acting against mammary carcinoma: pancreatic trypsin inhibitor.
Enzymatic modulation of the cell surface in malignant transformation of normal human mammary epithelial cells and in conversion of mammary carcinoma cells.
Establishment and characterization of a primary cell culture derived from external auditory canal squamous cell carcinoma.
Evaluation of urine tumor-associated trypsin inhibitor, CYFRA 21-1, and urinary bladder cancer antigen for detection of high-grade bladder carcinoma.
Experimental pancreatic hyperplasia and neoplasia: effects of dietary and surgical manipulation.
Experimental trypsin-induced urothelial cell separation in vivo.
Expression of matrix metalloproteinases and related tissue inhibitors in the cyst fluids of ovarian mucinous neoplasms.
Expression of urokinase and urinary trypsin inhibitor in metastatic and non-metastatic murine Lewis lung carcinoma cells.
Extrapancreatic trypsin-2 cleaves proteinase-activated receptor-2.
Identification of a Novel ITG?v?6-Binding Peptide Using Protein Separation and Phage Display.
Immunohistochemical study on pancreatic secretory trypsin inhibitor (PSTI) in gastric carcinomas.
Immunoreactive serum trypsin in diseases of the pancreas.
Inhibition of human natural cytotoxicity by macromolecular antiproteases.
Inhibition of metastasis of Lewis lung carcinoma by urinary trypsin inhibitor in experimental and spontaneous metastasis models.
Intracellular co-localization of trypsin-2 and matrix metalloprotease-9: possible proteolytic cascade of trypsin-2, MMP-9 and enterokinase in carcinoma.
Intraductal polypoid growth variant of pancreatic acinar cell carcinoma metastasizing to the intrahepatic bile duct 6 years after surgery: a case report and literature review.
Investigation on conformational variation and activity of trypsin affected by black phosphorus quantum dots via multi-spectroscopy and molecular modeling.
Investigations of conformational structure and enzymatic activity of trypsin after its binding interaction with graphene oxide.
Isolation and serial propagation of human group C rotaviruses in a cell line (CaCo-2).
Isolation of alpha 1-protease inhibitor from human normal and malignant ovarian tissue.
Isolation of Enterococcus faecalis clinical isolates that efficiently adhere to human bladder carcinoma T24 cells and inhibition of adhesion by fibronectin and trypsin treatment.
Limited loss of nine tumor-associated surface antigenic determinants after tryptic cell dissociation.
Lipase hypersecretion syndrome: A distinct form of paraneoplastic syndrome specific to pancreatic acinar carcinomas.
MMP-9 activation by tumor trypsin-2 enhances in vivo invasion of human tongue carcinoma cells.
Pancreatic acinar cell carcinoma with endocrine differentiation: immunohistochemical and ultrastructural analyses.
Pancreatic carcinoma with polyarthritis, fat necrosis, and high serum lipase and trypsin activity.
Pancreatic secretory trypsin inhibitor causes autocrine-mediated migration and invasion in bladder cancer and phosphorylates the EGF receptor, Akt2 and Akt3, and ERK1 and ERK2.
Pancreatic secretory trypsin inhibitor immunoreactivity detected in serum-free culture medium of human pancreatic carcinoma cell line, CAPAN-1.
Pancreatic secretory trypsin inhibitor stimulates the growth of rat pancreatic carcinoma cells.
Papillary cystic tumor of the pancreas. An analysis of cellular differentiation by electron microscopy and immunohistochemistry.
Possible adverse effects of soybean anticarcinogens.
Preoperative serum hCGbeta as a prognostic marker in primary fallopian tube carcinoma.
Propagation of human astrovirus in the PLC/PRF/5 hepatoma cell line.
Quantification of pancreatic secretory trypsin inhibitor in colonic carcinoma and normal adjacent colonic mucosa.
Rapid aggregation and tight junction formation in single cell suspensions of tumor cells after very low dose trypsin treatment.
Renal function and serum concentration of five tumor markers (TATI, SCC, CYFRA 21-1, TPA, and TPS) in patients without evidence of neoplasia.
Residue trypsin inhibitor: data needs for risk assessment.
Reverse-zymographic analysis of protease nexin-II/amyloid beta protein precursor of human carcinoma cell lines, with special reference to the grade of differentiation and metastatic phenotype.
Secretion of pancreatic secretory trypsin inhibitor by cultured human carcinoma cells.
Separation and characterization of epithelial cells from prostates and prostatic carcinomas: a review.
Serine protease inhibitor activity of recombinant squamous cell carcinoma antigen towards chymotrypsin, as demonstrated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.
Serum alpha-1 proteinase inhibitor in advanced cancer: mass variants and functionally inert forms.
Serum carcinoembryonic antigen, cancer antigen 125, cancer antigen 15-3, squamous cell carcinoma, and tumor-associated trypsin inhibitor concentrations during healthy pregnancy.
Serum proteolytic activities and antiproteases in human colorectal carcinoma.
Serum tumour associated trypsin inhibitor, as a biomarker for survival in renal cell carcinoma.
Smooth muscle-derived factor stimulates mobility of human tumor cells.
Specificity of reagents directed to the Thomsen-Friedenreich antigen and their capacity to bind to the surface of human carcinoma cell lines.
Sporamin suppresses growth of human esophageal squamous cell carcinoma cells by inhibition of NF??B via an AKT?independent pathway.
Squamous cell carcinoma antigen (SCC), carcinoembryonic antigen (CEA), and tumour-associated trypsin inhibitor (TATI) for monitoring head and neck cancer.
Squamous cell carcinoma antigen, tumor associated trypsin inhibitor and tissue polypeptide specific antigen in follow up of stage III cervical cancer.
Squamous cell carcinoma antigen, tumor-associated trypsin inhibitor, and carcinoembryonic antigen for monitoring cervical cancer.
Stimulation of cellular growth and adhesion to fibronectin and vitronectin in culture and tumorigenicity in nude mice by overexpression of trypsinogen in human gastric cancer cells.
Suppressing effects of dietary supplementation of soybean trypsin inhibitor on spontaneous, experimental and peritoneal disseminated metastasis in mouse model.
Teleocidin A2 inhibits human proteinase-activated receptor 2 signaling in tumor cells.
The relative values of serum immuno-reactive trypsin concentration and total amylase activity in the diagnosis of mumps, chronic renal failure, and pancreatic disease.
TPA, TATI, CEA, AFP, beta-HCG, PSA, SCC, and CA 19-9 for monitoring transitional cell carcinoma of the bladder.
Trypsin stimulates integrin alpha(5)beta(1)-dependent adhesion to fibronectin and proliferation of human gastric carcinoma cells through activation of proteinase-activated receptor-2.
Trypsin-2 Enhances Carcinoma Invasion by Processing Tight Junctions and Activating ProMT1-MMP.
Trypsinogen expression in human ovarian carcinomas.
Tumor associated trypsin inhibitor as a prognostic factor in renal cell carcinoma.
Tumor-Associated Trypsin Inhibitor (TATI) as a Biomarker of Poor Prognosis in Oropharyngeal Squamous Cell Carcinoma Irrespective of HPV Status.
Tumor-associated trypsin inhibitor (TATI) in primary esophageal carcinoma.
Tumor-associated trypsin inhibitor in normal and malignant renal tissue and in serum of renal-cell carcinoma patients.
Tumor-associated trypsin participates in cancer cell-mediated degradation of extracellular matrix.
Tumour-associated trypsin inhibitor and renal cell carcinoma.
Tumour-associated trypsin inhibitor in the diagnosis of pancreatic carcinoma.
Urinary levels of tumor-associated trypsin inhibitor (TATI) in the detection of transitional cell carcinoma of the urinary bladder.
Urinary trypsin inhibitor suppresses surgical stress-facilitated lung metastasis of murine colon 26-L5 carcinoma cells.
[Preparation of tumor cells from human lung cancer tissue for the purpose of cloning]
[Significance of the the tumor markers, Ca-125 and tumor-associated trypsin inhibitor in patients with carcinoma of the cervix and uterus]
[Successful Surgical Resection of Expansive-Growth Acinar Cell Carcinoma-A Case Report].
[Uniform method for determining the alpha 1-antitrypsin and alpha 2-macroglobulin activity in human blood serum (plasma)]
Carcinoma, Acinar Cell
Acinar cell carcinoma of the pancreas metastatic to the ovary: a report of 4 cases.
Differentiation of pancreatic acinar carcinoma cells cultured on rat testicular seminiferous tubular basement membranes.
Intraductal polypoid growth variant of pancreatic acinar cell carcinoma metastasizing to the intrahepatic bile duct 6 years after surgery: a case report and literature review.
Pancreatic acinar cell carcinoma with endocrine differentiation: immunohistochemical and ultrastructural analyses.
[Successful Surgical Resection of Expansive-Growth Acinar Cell Carcinoma-A Case Report].
Carcinoma, Adenosquamous
Bcl-10, trypsin and synaptophysin helps recognize acinar cell and mixed acinar neuroendocrine cell carcinoma of the pancreas on both preoperative cytological samples and needle biopsy specimens.
Carcinoma, Bronchogenic
Comparison of three methods for the determination of serum alpha-1-antitrypsin in patients with pulmonary diseases.
Carcinoma, Ehrlich Tumor
beta-Naphthylamidase activity of the cell surface of ehrlich ascites cells. Reversible control of enzyme activity by metal ions and thiols.
Biphasic kinetics of metal ion reactivation of trypsin-thiol complexes.
Changes in growth and adhesion of Ehrlich ascites tumour cells coated with trypsin inhibitor (soybean).
Characterization of plasma membrane redox activity from Ehrlich cells.
Effect of crude trypsin on incorporation of 3H-thymidine and 3H-uridine into the Ehrlich ascites tumour cells.
Evidence for the presence of a trypsin inhibitor within rabbit and mouse tumour cells.
Growth acceleration of Ehrlich ascites tumor cells treated by proteinase in vitro.
Inhibition of trypsin and chymotrypsin by thiols. Biphasic kinetics of reactivation and inhibition induced by sodium periodate addition.
Inhibition properties of Sepharose-bound trypsin and a protease on the surface of Ehrlich ascites tumour cells.
Internucleotide protein linkers in Ehrlich ascites cell DNA.
Mg2+- or Mn2+-dependent p-nitrophenylphosphatase activity is present in Ehrlich ascites tumor cells.
Proceedings: Independent responses of different binding sites on ehrlich ascites tumour cells to trypsin and trypsin inhibitor.
Proteolytic activity associated with tumour growth and metastasis. Influence of trypsin inhibitor (soya bean) on Ehrlich ascites tumour growth [proceedings].
The interaction of a trypsin-dependent neutral protease and its inhibitor found in tumour cells. Analysis of complex kinetic data involved in a thiol-disulphide exchange mechanism.
Carcinoma, Hepatocellular
A thermostable trypsin inhibitor with antiproliferative activity from small pinto beans.
Autoactivation and calpain-1-mediated shedding of hepsin in human hepatoma cells.
Brain- and liver cell-derived factors are required for growth of human endothelial cells in serum-free culture.
Changes in IL-6, IL-8, C-reactive protein and pancreatic secretory trypsin inhibitor after transcatheter arterial chemo-embolization therapy for hepato-cellular carcinoma.
Clinical and prognostic significance of urinary trypsin inhibitor in patients with hepatocellular carcinoma after hepatectomy.
Collagen cell attachment protein from rat hepatoma cells.
Cytotoxicity of tumour-bearer serum to D23 hepatoma cells derived from solid tumours, ascites or in vitro cultures.
Differences in cholesterol incorporation into mitochondria from hepatoma AS-30D and human term placenta.
Differential gel-based proteomic approach for cancer biomarker discovery using human plasma.
Direct stimulation of immediate-early genes by intranuclear insulin in trypsin-treated H35 hepatoma cells.
Effect of trypsin concentration on living SMCC-7721 cells studied by atomic force microscopy.
Effect of trypsin on morphological integrity and some functional activities of mitochondria from normal liver and AH-130 Yoshida ascites hepatoma.
Effect of trypsin on the cell surface proteins of hepatoma tissue culture cells. Characterization of a carbohydrate-rich glycopeptide released from a calcium binding membrane glycoprotein.
Enhanced proliferation of human hepatoma cells by PAR-2 agonists via the ERK/AP-1 pathway.
Expression of the pancreatic secretory trypsin inhibitor gene in the liver infected with hepatitis B virus.
Further observations on the effects of trypsin on the volume and functions of mitochondria isolated from normal liver and AH-130 Yoshida ascites hepatoma.
High permissivity of human HepG2 hepatoma cells for influenza viruses.
Identification of Chromosomal Aberrations by Using Trypsin G-banding in Hepatocellular Carcinoma Patients (HCC) in Tamil Nadu, India.
Immunoradioautographic study of alpha-fetoprotein in hepatoma cells.
Increased Serum Levels of Trypsin Inhibitor Kazal1 in Patients with HBV-Related Hepatocellular Carcinoma Predict a Poor Prognosis.
Inhibitory activity of polysaccharide extracts from three kinds of edible fungi on proliferation of human hepatoma SMMC-7721 cell and mouse implanted S180 tumor.
Insulin receptor regulation in minimal deviation hepatoma cell line.
Necrotic Response to Low Pathogenic H9N2 Influenza Virus in Chicken Hepatoma Cells.
Overexpression of tumor-associated trypsin inhibitor (SPINK1/TATI) in hepatitis C-associated hepatocellular carcinoma: potential implications for viral hepatocarcinogenesis.
Overexpression of tumour-associated trypsin inhibitor (TATI) enhances tumour growth and is associated with portal vein invasion, early recurrence and a stage-independent prognostic factor of hepatocellular carcinoma.
Plasma and urine levels of urinary trypsin inhibitor in patients with chronic liver diseases and hepatocellular carcinoma.
Preparation of single cell suspensions from hepatoma cells in culture.
Prognostic significance of tumor-associated trypsin inhibitor (TATI) and human chorionic gonadotropin-? (hCG?) in patients with hepatocellular carcinoma.
Proinflammatory cytokines up-regulate synthesis and secretion of urinary trypsin inhibitor in human hepatoma HepG2 cells.
Release of glycopeptides and mucopolysaccharides from ascites hepatoma cells by tryptic treatment.
Secretion of insulin-like growth factor binding protein-1 from individual hepatocytes.
Serum trypsin inhibitory capacity and alpha 1-antitrypsin levels in liver cirrhosis and hepatoma.
Specific expression of the pancreatic-secretory-trypsin-inhibitor (PSTI) gene in hepatocellular carcinoma.
Vascular sarcomas (probably angiosarcomas) transplanted from suspensions of liver cells from diethylnitrosamine-treated rats.
[Effect of ERK/AP-1 signaling pathway on proliferation of hepatoma cells induced by PAR-2 agonists]
[Enzymatic activity of cathepsin B, cathepsin B and L, plasmin, trypsin and collagenase in hepatocellular carcinoma]
[Growth of Zajdela ascites hepatoma cells in vivo following treatment with trypsin and pronase in vitro]
Carcinoma, Lewis Lung
Anti-metastatic therapy by urinary trypsin inhibitor in combination with an anti-cancer agent.
Expression of urokinase and urinary trypsin inhibitor in metastatic and non-metastatic murine Lewis lung carcinoma cells.
Inhibition of metastasis of Lewis lung carcinoma by urinary trypsin inhibitor in experimental and spontaneous metastasis models.
Suppressing effects of dietary supplementation of soybean trypsin inhibitor on spontaneous, experimental and peritoneal disseminated metastasis in mouse model.
Carcinoma, Lobular
Elastosis in breast carcinoma: II. Association of protease inhibitors with immature elastic fibres.
Carcinoma, Ovarian Epithelial
Comparison of tumor-associated trypsin inhibitor (TATI) with CA125 as a marker for diagnosis and monitoring of epithelial ovarian cancer.
Elevated serum insulin-like growth factor-binding protein 2 (IGFBP-2) and decreased IGFBP-3 in epithelial ovarian cancer: correlation with cancer antigen 125 and tumor-associated trypsin inhibitor.
Expression of trypsinogen-1, trypsinogen-2, and tumor-associated trypsin inhibitor in ovarian cancer: prognostic study on tissue and serum.
Maturation of dendritic cells from ovarian cancer patients.
Pre-operative serum level of tumour-associated trypsin inhibitor and residual tumour size as prognostic indicators in Stage III epithelial ovarian cancer.
Tumor-associated trypsin inhibitor (TATI) and cancer antigen 125 (CA125) in patients with epithelial ovarian cancer.
Carcinoma, Renal Cell
Characterization and purification of a guanidinobenzoatase: a possible marker of human renal carcinoma.
Serum tumour associated trypsin inhibitor, as a biomarker for survival in renal cell carcinoma.
Tumor associated trypsin inhibitor as a prognostic factor in renal cell carcinoma.
Tumour-associated trypsin inhibitor and renal cell carcinoma.
Carcinoma, Squamous Cell
A direct cytogenetic technique for mouse skin carcinomas and papillomas.
Association of trypsin expression with recurrence and poor prognosis in human esophageal squamous cell carcinoma.
Chemotherapy as initial treatment for cervical carcinoma: clinical and tumor marker response.
Comparative study of the novel RGD motif-containing ITG?v?6 binding peptides SFLAP3 and SFITGv6 for diagnostic application in HNSCC.
Establishment and characterization of a primary cell culture derived from external auditory canal squamous cell carcinoma.
Establishment of a new human cancer cell line secreting protease nexin-II/amyloid beta protein precursor derived from squamous-cell carcinoma of lung.
Evaluation of Mannosidase and Trypsin Enzymes Effects on Biofilm Production of Pseudomonas aeruginosa Isolated from Burn Wound Infections.
Identification of a Novel ITG?v?6-Binding Peptide Using Protein Separation and Phage Display.
Intracellular co-localization of trypsin-2 and matrix metalloprotease-9: possible proteolytic cascade of trypsin-2, MMP-9 and enterokinase in carcinoma.
Photodynamic therapy and tumor imaging of hypericin-treated squamous cell carcinoma.
Serine protease inhibitor activity of recombinant squamous cell carcinoma antigen towards chymotrypsin, as demonstrated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.
Serum carcinoembryonic antigen, cancer antigen 125, cancer antigen 15-3, squamous cell carcinoma, and tumor-associated trypsin inhibitor concentrations during healthy pregnancy.
Squamous cell carcinoma antigen (SCC), carcinoembryonic antigen (CEA), and tumour-associated trypsin inhibitor (TATI) for monitoring head and neck cancer.
Squamous cell carcinoma antigen, tumor associated trypsin inhibitor and tissue polypeptide specific antigen in follow up of stage III cervical cancer.
Squamous cell carcinoma antigen, tumor-associated trypsin inhibitor, and carcinoembryonic antigen for monitoring cervical cancer.
TPA, TATI, CEA, AFP, beta-HCG, PSA, SCC, and CA 19-9 for monitoring transitional cell carcinoma of the bladder.
Trypsin-2 Enhances Carcinoma Invasion by Processing Tight Junctions and Activating ProMT1-MMP.
Carcinoma, Transitional Cell
TPA, TATI, CEA, AFP, beta-HCG, PSA, SCC, and CA 19-9 for monitoring transitional cell carcinoma of the bladder.
Urinary levels of tumor-associated trypsin inhibitor (TATI) in the detection of transitional cell carcinoma of the urinary bladder.
Cardiomyopathies
Ectopic trypsin in the myocardium promotes dilated cardiomyopathy after influenza A virus infection.
[High level of immunoreactive circulating trypsin in primary myocardiopathy in cystic fibrosis]
Cardiomyopathy, Dilated
Ectopic trypsin in the myocardium promotes dilated cardiomyopathy after influenza A virus infection.
Cardiotoxicity
A lethal cardiotoxic-cytotoxic protein from the Indian monocellate cobra (Naja kaouthia) venom.
Cardiovascular Diseases
Leech thrombin inhibitors.
MRM-based, multiplexed, absolute quantitation of 45 proteins in human plasma.
The Morama Bean (Tylosema esculentum) A Potential Crop for Southern Africa.
carnitine o-palmitoyltransferase deficiency
Limited trypsin proteolysis renders carnitine palmitoyltransferase insensitive to inhibition by malonyl-CoA in patients with muscle carnitine palmitoyltransferase deficiency.
Cataract
Aspirin and prostacyclin treatment of diabetic dogs.
Calpain II induced insolubilization of lens beta-crystallin polypeptides may induce cataract.
Decrease in protein solubility and cataract formation caused by the Pro23 to Thr mutation in human gamma D-crystallin.
Direct approach to identification, at the molecular level, of modified proteins in human nuclear cataractous lenses: beta-crystallin is a component of the urea-insoluble protein fraction.
NMR study of the cataract-linked P23T mutant of human gammaD-crystallin shows minor changes in hydrophobic patches that reflect its retrograde solubility.
Proteases and protease inhibitory activities in normal mammalian lenses and human cataractous lenses.
The effects of aging and cataract formation on the trypsin inhibitor activity of human lens.
The human anterior lens capsule--an attempted chemical debridement of epithelial cells by ethylenediaminetetracetic acid (EDTA) and trypsin.
The P23T cataract mutation causes loss of solubility of folded gammaD-crystallin.
Trypsin and alpha-chymotrypsin in cataract surgery.
[30 years of cataract operation (author's transl)]
[New data on the use of trypsin in cataract surgery.]
[On cataract operations with trypsin using a zonula lacerater.]
[Studies on the effect of the pancreatic enzymes alpha-chymotrypsin and trypsin on the lens capsule in cataract extraction with enzymatic zonulysis.]
Celiac Disease
Nonceliac Gluten and Wheat Sensitivity.
Plasma cholecystokinin and pancreatic enzyme secretion in patients with coeliac sprue.
The interrelationship of enterokinase and trypsin activities in intractable diarrhea of infancy, celiac disease, and intravenous alimentation.
Time-related enzyme concentrations in duodenal aspirates after ingestion of a test meal.
Trypsin cleavage sites are highly unlikely to occur in celiac-causing restricted epitopes.
Cerebrovascular Disorders
[Effect of trypsin inhibitor on cerebral edema associated with cerebrovascular diseases]
Chagas Disease
Leishmania donovani donovani antigens recognized by kala-azar patient sera and identification of cross-reacting antigens to Chagas' disease.
Cholangiocarcinoma
Enhanced detection of cholangiocarcinoma with serum trypsinogen-2 in patients with severe bile duct strictures.
Proteinase-activated receptor 2 (PAR(2)) in cholangiocarcinoma (CCA) cells: effects on signaling and cellular level.
Relationship between pancreatic secretory trypsin inhibitor and early recurrence of intrahepatic cholangiocarcinoma following surgical resection.
Tumor-derived trypsin enhances proliferation of intrahepatic cholangiocarcinoma cells by activating protease-activated receptor-2.
Cholangitis, Sclerosing
The pancreas in primary biliary cirrhosis and primary sclerosing cholangitis.
Cholecystitis
Sphincter of Oddi function studied by radioimmunoassay of biliary trypsin in patients with bile duct stones and in controls.
Cholecystitis, Acute
Increased gallbladder trypsin in acute cholecystitis indicates functional disorder in the sphincter of oddi and could make EPT a logical procedure.
Increased gallbladder trypsin in acute cholecystitis indicates functional disorder in the sphincter of Oddi and could make EPT a logical procedure.
Serum trypsin levels in acute pancreatic and non-pancreatic abdominal conditions.
[Arginine esterase activity and the trypsin inhibitor level in the blood serum in different forms of acute cholecystitis]
Choledochal Cyst
Western blotting in the diagnosis of duodenal-biliary and pancreaticobiliary refluxes in biliary diseases.
Cholelithiasis
Increased gallbladder trypsin in acute cholecystitis indicates functional disorder in the sphincter of oddi and could make EPT a logical procedure.
Sphincter of Oddi function studied by radioimmunoassay of biliary trypsin in patients with bile duct stones and in controls.
Cholera
A procedure for the isolation of primary cultures of melanocytes from newborn and adult human skin.
Characterization of the essential transport function of the AIDA-I autotransporter and evidence supporting structural predictions.
Correlation between macrophages and their membrane fraction. Cytocidal activities on neoplastic cells.
Differences in growth requirements between epithelial and stromal cells derived from rat ventral prostate in serum-free primary culture.
Expression of gangliosides as receptors at the cell surface controls infection of NCTC 2071 cells by Sendai virus.
Growth of distal fetal rat lung epithelial cells in a defined serum-free medium.
Human leukocyte elastase induces keratinocyte proliferation by epidermal growth factor receptor activation.
Mesocestoides lineatus: trypsin induced development to adult mediated by Ca2+ and protein kinase C.
Metabolism of cholesterol, phosphatidylethanolamine and stearylamine analogues of GM1 ganglioside by rat glioma C6 cells.
Phenotypic modulation of hamster acinar cells by culture in collagen matrix.
Structure of the ceramide moiety of GM1 ganglioside determines its occurrence in different detergent-resistant membrane domains in HL-60 cells.
The biological activity of bovine and human thyrotropin is differently affected by trypsin treatment of human thyroid cells: thyroid-stimulating antibody is related to human thyrotropin.
[Differentiation of cholera Vibrio from El Tor vibrios by a trypsin broth medium. II. Heat-sterilized trypsin broth]
[Trypsin broth as a medium for cholera and El Tor vibrio. 1. Modification of the original formula]
Cholestasis
Effect of bile duct obstruction on pancreatic enzyme secretion and intestinal proteolytic enzyme activity in the rat.
Mechanisms for the pancreatic oncogenic effects of the peroxisome proliferator Wyeth-14,643.
Role of bile and trypsin in the release of cholecystokinin in humans.
Tumour-associated trypsin inhibitor in the diagnosis of pancreatic carcinoma.
Cholestasis, Extrahepatic
[Levels of serum immunoreactive trypsin in children with intra- and extrahepatic cholestasis]
Chondrosarcoma
An amino acid sequence common to both cartilage proteoglycan and link protein.
Characterization of binding properties of urinary trypsin inhibitor to cell-associated binding sites on human chondrosarcoma cell line HCS-2/8.
Isolation and characterization of proteoglycans from the swarm rat chondrosarcoma.
Light and electron microscopic studies on the localization of hyaluronic acid in developing rat cerebellum.
Monoclonal antibodies as probes for determining the microheterogeneity of the link proteins of cartilage proteoglycan.
The ultrastructure of cultures from the Swarm rat chondrosarcoma.
Choriocarcinoma
The role of cell membrane-associated urinary trypsin inhibitor in tumor cell invasion and metastasis.
Urinary trypsin inhibitor (UTI) and fragments derived from UTI by limited proteolysis efficiently inhibit tumor cell invasion.
[Bovine endothelial cell destruction by choriocarcinoma cell line (SMT-cc1) (inhibition of destruction by urinary trypsin inhibitor)]
Choroiditis
Retinal pathologic changes in multiple sclerosis.
Chronic Periodontitis
Phenotypic identification of Porphyromonas gingivalis validated with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
[Clinico-roentgenological assessment of the treatment of chronic periodontitis by trypsin electrophoresis of root canals]
Citrullinemia
An adult-onset case of argininosuccinate synthetase deficiency presenting with atypical citrullinemia.
High serum pancreatic secretory trypsin inhibitor before onset of type II citrullinemia.
Pancreatic secretory trypsin inhibitor as a diagnostic marker for adult-onset type II citrullinemia.
Pancreatic secretory trypsin inhibitor gene is highly expressed in the liver of adult-onset type II citrullinemia.
Classical Swine Fever
Hog cholera virus : sensitivity to hydrolytic enzymes.
Cleft Palate
In vitro manipulation of cleft palate connective tissue: setting the bases of a proposed new treatment.
coagulation factor xiia deficiency
Phosphatidylethanolamine participates in the stimulation of the contact system of coagulation by very-low-density lipoproteins.
Coccidiosis
[Changes in the intestinal activity of trypsin through bivalent cations and their determination by means of appendix coccidiosis]
Coinfection
Avian influenza virus h3 hemagglutinin may enable high fitness of novel human virus reassortants.
Colitis
Pancreatic and granulocytic endoproteases in faecal extracts from patients with active ulcerative colitis.
Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome.
The beneficial effect of combination therapy with sulfasalazine and valsartan in the treatment of ulcerative colitis.
Unconjugated bilirubin ameliorates the inflammation and digestive protease increase in TNBS-induced colitis.
Wheat Consumption Aggravates Colitis in Mice via Amylase Trypsin Inhibitor-mediated Dysbiosis.
[Activity of trypsin, its inhibitors and antiinhibitors in blood serum of patients with chronic colitis and enterocolitis]
Colitis, Ulcerative
A trial of intravenous trypsin in the treatment of chronic ulcerative colitis.
Colonic proteinases: increased activity in patients with ulcerative colitis.
Immunoreactive pancreatic secretory trypsin inhibitor in sera from patients with acute ulcerative colitis.
Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2.
Investigation of the role of pancreatic trypsin in ulcerative colitis.
Pancreatic and granulocytic endoproteases in faecal extracts from patients with active ulcerative colitis.
Secretory leukocyte protease inhibitor in punch biopsies from human colonic mucosa.
Colonic Diseases
[Trypsin and chymotrypsin in the differential diagnosis of inflammatory colonic diseases]
Colonic Neoplasms
Association of trypsin expression with tumour progression and matrilysin expression in human colorectal cancer.
ATP requirement for induced tight junction formation in HT 29 adenocarcinoma cells.
Autocrine induction of invasion and metastasis by tumor-associated trypsin inhibitor in human colon cancer cells.
BG-4, a novel anticancer peptide from bitter gourd (Momordica charantia), promotes apoptosis in human colon cancer cells.
Cbl-b accelerates trypsin-induced cell detachment through ubiquitination and degradation of proline-rich tyrosine kinase 2.
Induction of colon adenocarcinomas in rats fed trypsin and tamoxifen diets by parenteral and intragastric 1,2-dimethylhydrazine.
Initiation of human colon cancer cell proliferation by trypsin acting at protease-activated receptor-2.
Interdicting protease-activated receptor-2-driven inflammation with cell-penetrating pepducins.
Kallikrein-related peptidase 14 acts on proteinase-activated receptor 2 to induce signaling pathway in colon cancer cells.
Pancreatic trypsinogen I expression during cell growth and differentiation of two human colon carcinoma cells.
Protease-activated receptor 2 in colon cancer: trypsin-induced MAPK phosphorylation and cell proliferation are mediated by epidermal growth factor receptor transactivation.
Selection by trypsin of two sublines of rat colon cancer cells forming progressive or regressive tumors.
Trypsin is produced by and activates protease-activated receptor-2 in human cancer colon cells: evidence for new autocrine loop.
Colorectal Neoplasms
Association of trypsin expression with tumour progression and matrilysin expression in human colorectal cancer.
Co-expression of trypsin and tumour-associated trypsin inhibitor (TATI) in colorectal adenocarcinomas.
Effects of radiation therapy on tissue and serum concentrations of tumour associated trypsin inhibitor and their prognostic significance in rectal cancer patients.
Expression of pancreatic secretory trypsin inhibitor (PSTI) in colorectal cancer.
Expression of pancreatic secretory trypsin inhibitor gene in human colorectal tumor.
High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer.
Increased serum levels of tumour-associated trypsin inhibitor independently predict a poor prognosis in colorectal cancer patients.
New intracellular and molecular aspects in pathophysiology of colorectal cancer.
Reconstructed mung bean trypsin inhibitor targeting cell surface GRP78 induces apoptosis and inhibits tumor growth in colorectal cancer.
Serum proteolytic activities and antiproteases in human colorectal carcinoma.
The measurement of serum immunoreactive pancreatic secretory trypsin inhibitor in gastrointestinal cancer and pancreatic disease.
The silk of Plodia interpunctella as a potential biomaterial and its cytotoxic effect on cancer cells.
Trypsin in colorectal cancer: molecular biological mechanisms of proliferation, invasion, and metastasis.
Tumor-associated trypsin inhibitor (TATI) in patients with colorectal carcinoma. A critical comparison with CEA.
Tumor-derived suppressor factors (TDSFs) in normal and neoplastic colon and rectum.
Tumour-associated trypsin inhibitor (TATI) in patients with colorectal cancer: a comparison with CEA, CA 50 and CA 242.
Tumour-associated trypsin inhibitor TATI is a prognostic marker in colorectal cancer.
[Expression of trypsin and cancer proliferation in colorectal neoplasms]
Common Cold
Does Trypsin Oral Spray (Viruprotect®/ColdZyme®) Protect against COVID-19 and Common Colds or Induce Mutation? Caveats in Medical Device Regulations in the European Union.
Conjunctivitis, Allergic
Trypsin inhibitory capacity in vernal keratoconjunctivitis.
Connective Tissue Diseases
Bolus infusion of human urinary trypsin inhibitor improves intractable interstitial pneumonia in patients with connective tissue diseases.
Effect of enzyme treatment of Chrithidia luciliae on the reactivity of its kinetoplast with anti-DNA sera.
Contracture
Losartan counteracts the hyper-reactivity to angiotensin II and ROCK1 over-activation in aortas isolated from streptozotocin-injected diabetic rats.
Neuromuscular actions of sodium selenite on chick biventer cervicis nerve-muscle preparation.
Studies on the contracture inducing action of triphenyltin in the mouse diaphragm.
Studies on the contracture of the mouse diaphragm induced by sodium selenite.
Corneal Diseases
Using soybean trypsin inhibitor as an external loading control for Western blot analysis of tear proteins: application to corneal disease.
Corneal Dystrophies, Hereditary
Mutation in transforming growth factor beta induced protein associated with granular corneal dystrophy type 1 reduces the proteolytic susceptibility through local structural stabilization.
Corneal Injuries
[Experimental studies on corneal injuries by alpha-chymotrypsin and trypsin.]
Coronary Artery Disease
Comparison of the effects of ramipril versus telmisartan in reducing serum levels of high-sensitivity C-reactive protein and oxidized low-density lipoprotein cholesterol in patients with type 2 diabetes mellitus.
Coronary Thrombosis
Use of trypsin in the treatment of experimental coronary thrombosis.
Coronavirus Infections
Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection.
Cough
Enzymatic débridement; particular reference to trypsin and desoxyribonuclease in the control of cough and sputum associated with tuberculosis.
COVID-19
Does Trypsin Oral Spray (Viruprotect®/ColdZyme®) Protect against COVID-19 and Common Colds or Induce Mutation? Caveats in Medical Device Regulations in the European Union.
Liquid Chromatography-Multiple Reaction Monitoring-Mass Spectrometry Assay for Quantitative Measurement of Therapeutic Antibody Cocktail REGEN-COV Concentrations in COVID-19 Patient Serum.
Cowpox
An antigenically atypical strain of variola virus.
The effect of trypsin on the formation of virus-specific surface antigen in cowpox virus-infected cells.
Crohn Disease
Antibodies to a trypsin sensitive pancreatic antigen in chronic inflammatory bowel disease: specific markers for a subgroup of patients with Crohn's disease.
Concentrations of pancreatic secretory trypsin inhibitor (PSTI), acute phase proteins, and neopterin in Crohn's disease. Comparison with clinical disease activity and endoscopical findings.
Impaired luminal processing of human defensin-5 in Crohn's disease: persistence in a complex with chymotrypsinogen and trypsin.
Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2.
Levels of trypsin and alpha-chymotrypsin in feces from patients with Crohn's disease.
[Immunoreactive trypsin in the serum of normal children and children with gastrointestinal diseases]
Cryptorchidism
The Prader-Willi syndrome with a 15/3 translocation.
The thermo-sensitive gene expression signatures of spermatogenesis.
Cystadenoma
Differential expression of trypsin in human ovarian carcinomas and low-malignant-potential tumors.
Primary retroperitoneal acinar cell cystadenoma.
Cystic Fibrosis
A high prevalence of genetic polymorphisms in idiopathic and alcohol-associated chronic pancreatitis patients in Ireland.
Abnormal breakdown of alpha2-macroglobulin-trypsin complex in cystic fibrosis.
Abnormalities of circulating immunoreactive pancreatic anionic trypsinogen in cystic fibrosis: an assay artifact due to cross-reacting serum antibodies.
Absence of an alpha two-macroglobulin-protease complex in cystic fibrosis.
Activation of normal and cystic fibrosis Cl- channels by voltage, temperature, and trypsin.
Age-related alterations in immunoreactive pancreatic lipase and cationic trypsinogen in young children with cystic fibrosis.
Age-related alterations of immunoreactive pancreatic cationic trypsinogen in sera from cystic fibrosis patients with and without pancreatic insufficiency.
Amniotic immunoreactive trypsin in pregnancies with normal and pathological outcomes.
An evaluation of an enzyme immunoassay method for immunoreactive trypsin in dried blood spots.
An integrated liquid crystal sensing device assisted by the surfactant-embedded smart hydrogel.
Analysis of the human pancreatic secretory trypsin inhibitor (PSTI) gene mutations in Japanese patients with chronic pancreatitis.
Antibodies cross-reacting with porcine and human trypsin in cystic fibrosis.
Assay of serum immunoreactive trypsin in dried blood spots and the early detection of cystic fibrosis.
Assessment of pancreatic function in screened infants with cystic fibrosis.
Association Analyses of Genetic Polymorphisms of GSTM1, GSTT1, NQO1, NAT2, LPL, PRSS1, PSTI, and CFTR With Chronic Alcoholic Pancreatitis in Japan.
Association of cystic fibrosis transmembrane conductance regulator (CFTR) mutation/variant/haplotype and tumor necrosis factor (TNF) promoter polymorphism in hyperlipidemic pancreatitis.
Behaviour of serum immunoreactive trypsin after serum activation by enterokinase in normal and cystic fibrosis patients. Evidence of a trypsin-alpha 1-proteinase inhibitor complex in some cystic fibrosis patients.
beta Cell reserve in cystic fibrosis patients and heterozygotes.
Carboxypeptidase A activity of cultured skin fibroblasts and relationship to cystic fibrosis.
CFTR, PRSS1 and SPINK1 mutations in the development of pancreatitis in Brazilian patients.
CFTR, SPINK1, PRSS1, and CTRC Mutations Are Not Associated With Pancreatic Cancer in German Patients.
Chronic pancreatitis associated with the p.G208A variant of PRSS1 gene in a European patient.
Chronic pancreatitis.
Chronic pancreatitis: controversies in etiology, diagnosis and treatment.
Cigarette smoke-induced differential expression of the genes involved in exocrine function of the rat pancreas.
Clinical and radiological outcome of patients suffering from chronic pancreatitis associated with gene mutations.
Clinical evidence of pathogenesis in chronic pancreatitis.
Combined Bicarbonate Conductance-Impairing Variants in CFTR and SPINK1 Are Associated with Chronic Pancreatitis in Patients without Cystic Fibrosis.
Comparison between purified alpha2-macroglobulin preparations from normal controls and patients with cystic fibrosis. Kinetic and structural properties of the complex with bovine trypsin.
Comparison of the diagnostic value of serum pancreatic isoamylase and immunoreactive trypsin measurement in patients with cystic fibrosis.
Comparison of two different protocols of neonatal screening for cystic fibrosis.
Competition for trypsin binding between alpha 2-macroglobulin and antitrypsin antibodies in cystic fibrosis.
Comprehensive screening for PRSS1, SPINK1, CFTR, CTRC and CLDN2 gene mutations in Chinese paediatric patients with idiopathic chronic pancreatitis: a cohort study.
Concentrations of trypsin, elastase and carbohydrate antigen CA 19-9 in serum of cystic fibrosis patients.
Conclusions from a pilot immunoreactive trypsin newborn screen for cystic fibrosis.
Cost-effectiveness of 4 neonatal screening strategies for cystic fibrosis.
Cystic fibrosis alpha 2-macroglobulin protease interaction in vitro.
Cystic fibrosis gene mutations and pancreatitis risk: relation to epithelial ion transport and trypsin inhibitor gene mutations.
Cystic fibrosis identified by neonatal screening: incidence, genotype, and early natural history.
Cystic fibrosis newborn screening: outcome of infants with normal sweat tests.
Cystic fibrosis newborn screening: the importance of bloodspot sample quality.
Cystic fibrosis screening by dried blood spot trypsin assay: results in 75,000 newborn infants.
Cystic fibrosis screening in neonates--measurement of immunoreactive trypsin and direct genotype analysis for delta F508 mutation.
Cystic fibrosis--its biochemical detection.
Cystic-fibrosis screening in the newborn.
Decreased immunoreactive trypsin levels in sera from cystic fibrosis patients.
Deficiency of arginine esterase in cystic fibrosis of the pancreas: demonstration of the proteolytic nature of the activity.
Determination and characterization of immunoreactive trypsin in amniotic fluid from normal and cystic fibrosis fetuses.
Determination of the relative contribution of three genes-the cystic fibrosis transmembrane conductance regulator gene, the cationic trypsinogen gene, and the pancreatic secretory trypsin inhibitor gene-to the etiology of idiopathic chronic pancreatitis.
Development of a screening system for cystic fibrosis: meconium or blood spot trypsin assay or both?
Diagnosis and Management of Chronic Pancreatitis: A Review.
Diagnosis of cystic fibrosis, by assay of immuno-reactive trypsin in a newborn infant with jejuno-ileal atresias.
Diagnostic delay in cystic fibrosis: lessons from newborn screening.
Differences in immunoreactive trypsin values between type of feeding and ethnicity in neonatal cystic fibrosis screening: a cross-sectional study.
Does cystic fibrosis neonatal screening detect atypical CF forms? Extended genetic characterization and 4-year clinical follow-up.
Dual core quantum dots for highly quantitative ratiometric detection of trypsin activity in cystic fibrosis patients.
Effect of pancreozymin and secretin on intraluminal enterokinase, trypsin, and chymotrypsin activities of cystic fibrosis and control children.
Enterokinase and trypsin activities in pancreatic insufficiency and diseases of the small intestine.
Environmental risk factors for chronic pancreatitis and pancreatic cancer.
Evidence that hereditary pancreatitis is genetically heterogeneous disorder.
Exocrine pancreatic function in cystic fibrosis.
False-positive results of genetic testing in cystic fibrosis.
Genetic aspects of pancreatitis.
Genetic counseling for hereditary pancreatitis--the role of molecular genetics testing for the cationic trypsinogen gene, cystic fibrosis and serine protease inhibitor Kazal type 1.
Genetic Evaluation of Children with Idiopathic Recurrent Acute Pancreatitis.
Genetic factors in chronic pancreatitis; implications for diagnosis, management and prognosis.
Genetic factors in pancreatitis.
Genetic issues in pediatric pancreatitis.
Genetic polymorphisms in alcoholic pancreatitis.
Genetic testing in acute and chronic pancreatitis.
Genetics and pancreatic disease.
Genetics of acute and chronic pancreatitis: An update.
Genetics of chronic pancreatitis.
Germline mutations and gene polymorphism associated with human pancreatitis.
Germline mutations in CFTR and PSTI genes in chronic pancreatitis patients.
Hereditary chronic pancreatitis.
Hereditary pancreatitis in childhood: course of disease and complications.
Hereditary pancreatitis in Japan: a review of pancreatitis-associated gene mutations.
High serum immunoreactive trypsin not caused by cystic fibrosis.
History of Newborn Screening for Cystic Fibrosis-The Early Years.
Identification of a Novel Frame-Shift Mutation in PRSS1 Gene in Han Patients with Autoimmune Pancreatitis.
Identification of patients with genetic risk factors of pancreatitis: impact on treatment and cancer prevention.
Idiopathic pancreatitis related to CFTR: complex inheritance and identification of a modifier gene.
Immaturity of the myenteric plexus is the aetiology of meconium ileus without mucoviscidosis: a histopathologic study.
Immunoreactive serum trypsin in diseases of the pancreas.
Immunoreactive trypsin and the prenatal diagnosis of cystic fibrosis.
Immunoreactive trypsin in cystic fibrosis.
Immunoreactive trypsin levels in neonates with meconium ileus.
Immunoreactive trypsin levels in young cystic fibrosis patients and in other sick children.
Immunoreactive trypsin on dried-blood spots as a possible neonatal test for cystic fibrosis. (I. Evaluation of the method and preliminary field trial).
Immunoreactive trypsin screening for cystic fibrosis.
Immunoreactive trypsin, chymotrypsin, and pancreatic secretory trypsin inhibitor in cord blood from infants with cystic fibrosis.
Immunoreactive trypsin/DNA newborn screening for cystic fibrosis: should the R117H variant be included in CFTR mutation panels?
Indirect parameters of pancreatic function in cystic fibrosis (CF) during a controlled double-blind trial of pancreatic supplementation.
Laboratory quality control issues related to screening newborns for cystic fibrosis using immunoreactive trypsin.
Levels and molecular forms of immunoreactive trypsin and chymotrypsin in amniotic fluids from normal and cystic fibrosis fetus: evidence for a lack of activation of proteolytic zymogens in cystic fibrosis fetus.
Longitudinal evaluation of serum trypsinogen measurement in pancreatic-insufficient and pancreatic-sufficient patients with cystic fibrosis.
Low sweat electrolytes in a patient with cystic fibrosis.
Molecular understanding of chronic pancreatitis: a perspective on the future.
Motion--genetic testing is useful in the diagnosis of nonhereditary pancreatic conditions: arguments against the motion.
Motion--genetic testing is useful in the diagnosis of nonhereditary pancreatic conditions: arguments for the motion.
Mutation analysis of the cystic fibrosis and cationic trypsinogen genes in patients with alcohol-related pancreatitis.
Mutation analysis of the cystic fibrosis transmembrane conductance regulator (CFTR) gene, the cationic trypsinogen (PRSS1) gene, and the serine protease inhibitor, Kazal type 1 (SPINK1) gene in patients with alcoholic chronic pancreatitis.
Mutations of the cystic fibrosis gene, but not cationic trypsinogen gene, are associated with recurrent or chronic idiopathic pancreatitis.
Mutations of the serine protease inhibitor, Kazal type 1 gene, in patients with idiopathic chronic pancreatitis.
Neonatal cystic fibrosis screening: Analysis and differences in immunoreactive trypsin levels in newborns with a positive screen.
Neonatal infection does not affect the immunoreactive trypsinogen screening test for cystic fibrosis.
Neonatal screening for cystic fibrosis by dried blood spot trypsin assay. Results in 47 127 newborn infants from a homogeneous population.
Neonatal screening for cystic fibrosis in the Trent region (UK): two-stage immunoreactive trypsin screening compared with a three-stage protocol with DNA analysis as an intermediate step.
Neonatal screening for cystic fibrosis in Wales and the West Midlands: 1. Evaluation of immunoreactive trypsin test.
Neonatal screening for cystic fibrosis in Wales and the West Midlands: clinical assessment after five years of screening.
Neonatal screening for cystic fibrosis, using immunoreactive trypsin assay in dried blood spots.
Newborn screening for cystic fibrosis: Educational implications.
Newborn screening methods for cystic fibrosis.
Newborn screening strategy for cystic fibrosis: a field study in an area with high allelic heterogeneity.
Non-competitive enzyme immunoassay of human trypsin 1.
Normal subunit cleavage of alpha-2-macroglobulin in cystic fibrosis.
Pancreatic fluid secretion and protein hyperconcentration in cystic fibrosis.
Pancreatitis risk in primary hyperparathyroidism: relation to mutations in the SPINK1 trypsin inhibitor (N34S) and the cystic fibrosis gene.
Pericellular glycoconjugates of cultured fibroblasts from control and cystic fibrosis patients.
Plasma arginine esterase activity in cystic fibrosis of the pancreas.
Plasma immunoreactive anionic pancreatic trypsin in cystic fibrosis.
Plasma immunoreactive cationic trypsin(ogen) pattern in reserpinized rat model of cystic fibrosis. Resemblance to humans.
Plasma immunoreactive pancreatic cationic trypsinogen in cystic fibrosis: a sensitive indicator of exocrine pancreatic dysfunction.
Presence of SPINK-1 variant alters the course of chronic pancreatitis.
Prognosis in cystic fibrosis treated with continuous flucloxacillin from the neonatal period.
Protease inhibitor and defective proteolysis in cystic fibrosis.
PRSS1 intron mutations in patients with pancreatic cancer and chronic pancreatitis.
Rapid semiquantitative tests for trypsin and chymotrypsin application to screening for cystic fibrosis, enterokinase deficiency and pancreatic hypoplasia in neonates.
Reduced CFTR function and the pathobiology of idiopathic pancreatitis.
Relevance of variants in serum antiproteinases for the course of chronic pancreatitis.
Screening for cystic fibrosis by a stool trypsin method.
Screening for cystic fibrosis by died blood spot trypsin assay.
Secretin pancreozymin stimulation test and confirmation of the diagnosis of cystic fibrosis.
Sensitive trypsin assay for dried-blood specimens as a screening procedure for early detection of cystic fibrosis.
Serum immuno reactive trypsin and pancreatic isoamylase in older patients with cystic fibrosis.
Serum immunoglobulin G directed against porcine trypsin in pancreatic insufficient cystic fibrosis patients receiving pancreatic enzyme supplements.
Serum immunoglobulin G directed against porcine trypsin in the serum of cystic fibrosis children receiving porcine pancreatic enzyme supplements.
Serum immunoreactive cationic trypsinogen: a useful indicator of severe exocrine dysfunction in the paediatric patient without cystic fibrosis.
Serum immunoreactive pancreatic lipase and cationic trypsinogen for the assessment of exocrine pancreatic function in older patients with cystic fibrosis.
Serum immunoreactive trypsin and pancreatic lipase in cystic fibrosis.
Serum immunoreactive trypsin in cystic fibrosis.
Serum lipase and trypsin in neonatal detection of cystic fibrosis.
Serum pancreatic lipase activity in cystic fibrosis.
Serum pancreatic lipase as a screening test for cystic fibrosis.
Silica nanoparticle-based microfluidic immunosensor with laser-induced fluorescence detection for the quantification of immunoreactive trypsin.
Stool trypsin and chymotrypsin. Value in the diagnosis of pancreatic insufficiency in cystic fibrosis.
Studies on cystic fibrosis of the pancreas; role of various diluents and the dilution factor in the interpretation of the x-ray film test for fecal trypsin.
Targeted Gene Next-Generation Sequencing in Chinese Children with Chronic Pancreatitis and Acute Recurrent Pancreatitis.
The application of PCR amplification and the polymorphic marker KM.19 to dried blood spots: comparison with deletion 508 for the confirmation of the neonatal screening test for cystic fibrosis.
The neonatal detection of cystic fibrosis by measurement of immunoreactive trypsin in blood.
The noninvasive biochemical diagnosis of gastrointestinal disease, with special reference to children.
The pancreatitis-associated protein (PAP). A new candidate for neonatal screening of cystic fibrosis.
The Prevalence and Characteristics of Genetic Pancreatitis in Children with Chronic and Recurrent Acute Pancreatitis.
Titrimetric measurements of fecal trypsin and chymotrypsin in cystic fibrosis with pancreatic exocrine insufficiency.
Trisomy 18, cystic fibrosis, and blood immunoreactive trypsin.
Trypsin activity in stool and duodenal aspirate of neonates for differential diagnosis of intestinal obstruction.
Trypsin binding activity of alpha 2-macroglobulin in cystic fibrosis and other lung diseases.
Trypsin Detection Strategies: A Review.
Use of radioimmunoassay for serum trypsin in cystic fibrosis.
[A new strategy of neonatal screening for cystic fibrosis. The association of immunoreactive trypsin and molecular biology in dried blood]
[Determination of trypsin in dried blood for neonatal detection of cystic fibrosis]
[Early detection of mucoviscidosis patients using trypsin RIA in dried blood stains]
[Film test for fecal trypsin in diagnosis of mucoviscidosis.]
[From the chronic pancreatitis to chronic pancreatites]
[Genetic aspects of digestive diseases. Part 1]
[Genetic mutations as a cause of acute recurrent pancreatitis in children - case report and literature review].
[High level of immunoreactive circulating trypsin in primary myocardiopathy in cystic fibrosis]
[Immunoreactive trypsin in the serum of normal children and children with gastrointestinal diseases]
[Interest in pediatrics in the value of trypsin by the radioimmunologic method]
[Mucoviscidosis screening by determination of immunoreactive trypsin]
[Mucoviscidosis screening with immunoreactive trypsin. Initial experiences in Austria]
[Mucoviscidosis screening with immunoreactive trypsin]
[Neonatal cystic fibrosis screening program in the state of Paraná: evaluation 30 months after implementation]
[Neonatal cystic fibrosis screening: Analysis and differences in immunoreactive trypsin levels in newborns with a positive screen].
[Neonatal cystic fibrosis: report of 2 cases]
[Neonatal screening of mucoviscidosis using radioimmunologic levels of trypsin in dried blood eluates]
[Pancreatitis-associated gene mutations]
[Radio-immuno-assay for trypsin in newborn-screening for cystic fibrosis]
[Radioimmunoassay of trypsin in dried blood. Importance for the neonatal detection of cystic fibrosis (author's transl)]
[Regional mucoviscidosis screening using immunoreactive trypsin in umbilical cord blood]
[Screening for hereditary diseases. What other screening?]
[Screening of newborn infants for cystic fibrosis. A combined analysis of immunoreactive trypsin and delta F508 mutation--a screening without false positive results]
[Systematic neonatal screening for mucoviscidosis using an immunoreactive trypsin blood assay. Evaluation of 80,000 tests]
[The ?F508 mutation in cystic fibrosis patients.]
[Trypsin in the meconium in healthy subjects and subjects with cystic fibrosis]
Cystitis
Involvement of bradykinin in trypsin-induced urinary bladder contraction in cyclophosphamide-treated rats.
[Study on infectious mechanism of type 1 fimbriated Escherichia coli in experimental cystitis of mice]
[Treatment of acute radiation cystitis with preparations of immobilized trypsin]
Cysts
A freeze-fracture study of the host cell-parasite interface during and after invasion of cultured cells by cystozoites of Sarcocystis muris.
A novel method for isolating lymphatic endothelial cells from lymphatic malformations and detecting PIK3CA somatic mutation in these isolated cells.
A serine proteinase in the penetration glands of the hexacanths of Hymenolepis diminuta (Cestoda, Cyclophyllidea).
An endosymbiotic Chlorella-bearing ciliate: Platyophrya chlorelligera Kawakami 1989.
Biochemical and enzymatic characterization of decapsulated cysts and nauplii of the brine shrimp Artemia at different developmental stages.
Cancer-associated antigen CA 195 in patients with mucinous ovarian tumours: a comparative analysis with CEA, TATI and CA 125 in serum specimens and cyst fluids.
Carbohydrate and amino acid analyses of Giardia muris cysts.
Characterization of phospholipase A2 activity in aspirates of human pancreatic pseudocysts after isolation by reversed-phase high performance liquid chromatography.
Cyst fluid of ovarian cancer patients contains high concentrations of trypsinogen-2.
Cyst fluid proteases.
Cyst fluid tumor-associated trypsin inhibitor may be helpful in the differentiation of cystic pancreatic lesions.
Cystoisospora canis (Apicomplexa: Sarcocystidae): Development of monozoic tissue cysts in human cells, demonstration of egress of zoites from tissue cysts, and demonstration of repeat monozoic tissue cyst formation by zoites.
Detection of trypsin- and chymotrypsin-like proteases using p-nitroanilide substrates after sodium dodecyl sulphate polyacrylamide gel electrophoresis.
Early-Onset Acute Recurrent and Chronic Pancreatitis Is Associated with PRSS1 or CTRC Gene Mutations.
Effect of emetine hydrochloride on cysts of amoebae in presence of trypsin and lysozyme.
Effect of proteolytic enzymes on Pneumocystis carinii in rat lung tissue.
Enhanced transgenic plant resistance to nematodes by dual proteinase inhibitor constructs.
Excystation of in vitro-derived Giardia lamblia cysts.
Factors promoting in vitro excystation of Giardia muris cysts.
Human colon carcinoma, fibrosarcoma and leukemia cell lines produce tumor-associated trypsinogen.
Human ovarian tumor-associated trypsin. Its purification and characterization from mucinous cyst fluid and identification as an activator of pro-urokinase.
Immunodetection of Pneumocystis carinii in bronchoalveolar lavage specimens compared with methenamine silver stain.
In vitro excystment of the metacercariae of Cloacitrema michiganensis (Trematoda: Philophthalmidae).
In vivo and in vitro excystation of Zygocotyle lunata (Trematoda) metacercariae and histochemical observations on the cyst.
Observations on the life-cycle of the strigeoid trematode, Apatemon (Apatemon) gracilis (Rudolphi, 1819) Szidat, 1928.
Post-obstructive cyst formation in pancreas and cystic acinar transformation: Are they same?
Preparation and applicability of Sarcocystis cruzi antigens and their anti-S. cruzi rabbit sera for serodiagnosis of bovine sarcocystosis.
Sporamin-mediated resistance to beet cyst nematodes (Heterodera schachtii Schm.) is dependent on trypsin inhibitory activity in sugar beet (Beta vulgaris L.) hairy roots.
Studies on encystment of Echinostoma revolutum cercariae.
The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation.
Ultrastructural and molecular characterization of Sarcocystis isolated from camel (Camelus dromedarius) in Iran.
Western blotting in the diagnosis of duodenal-biliary and pancreaticobiliary refluxes in biliary diseases.
[Isolation of germinal cells from the secondary cysts of Echinococcus granulosus harbored in mice]
Cytomegalovirus Infections
Serum pancreatic enzymes in HIV-seropositive patients.
Cytomegalovirus Retinitis
A quantitative and cartographic study of retinal microvasculopathy in acquired immunodeficiency syndrome.
Deafness
Familial idiopathic hypoparathyroidism, sensorineural deafness and renal dysplasia.
[A biochemical and cytological explanation of cochlear otospongiosis]
[The genetics of the protease inhibitor system and osteospongiosis. Statistical study in 199 patients]
Dehydration
An immunocytochemical investigation of trypsin secretion in the midgut of the stablefly, Stomoxys calcitrans.
Comparative evaluation of bioactivity of crystalline trypsin for drying by Fourier-transformed infrared spectroscopy.
Impaired drinking response in histamine H3 receptor knockout mice following dehydration or angiotensin-II challenge.
Improvement of automatic in-gel digestion by in situ alkylation of proteins.
NisP is related to nisin precursor processing and possibly to immunity in Lactococcus lactis.
Studies on immobilized trypsin in high concentrations of organic solvents.
Water structuring centers of mammalian cell surfaces.
[The content of abscisic acid and the activities of proteinases and trypsin inhibitory proteins in the germinating seed of common beans under conditions of water stress]
[Therapeutic effects and influence on the urinary enzyme activity of human urinary trypsin inhibitor (urinastatin) in cases with acute renal failure--changes in the urinary activities of NAG and AAP]
Dementia
Amyloid beta protein precursors with kunitz-type inhibitor domains and acetylcholinesterase in cerebrospinal fluid from patients with dementia of the Alzheimer type.
Trypsin inhibition: a potential cause of cobalamin deficiency common to the pathogenesis of Alzheimer-type dementia and AIDS dementia complex?
Demyelinating Diseases
An electrophysiological and histological study of trypsin induced demyelination.
Cerebrospinal fluid of HTLV-1 associated myelopathy patients induces axonal sproutings and Schwann cell proliferation in the rat sciatic nerve.
Fluidity of the myelin sheath in the peripheral nerves of diabetic rats.
Dengue
A propeptide-independent protease from Tannerella sp.6_1_58FAA_CT1 displays trypsin-like specificity.
A small molecule fusion inhibitor of dengue virus.
Adaptation of the plaque assay methodology for dengue virus infected HepG2 cells.
Architecture of the flaviviral replication complex. Protease, nuclease, and detergents reveal encasement within double-layered membrane compartments.
Evidence for two mechanisms of dengue virus infection of adherent human monocytes: trypsin-sensitive virus receptors and trypsin-resistant immune complex receptors.
Internalization and propagation of the dengue virus in human hepatoma (HepG2) cells.
Organization of flaviviral replicase proteins in virus-induced membranes: a role for NS1' in Japanese encephalitis virus RNA synthesis.
The sensitivity of cell-associated dengue virus proteins to trypsin and the detection of trypsin-resistant fragments of the nonstructural glycoprotein NS1.
Dental Caries
Characterization of multiply phosphorylated peptides selectively precipitated from a pancreatic casein digest.
Self-limiting caries therapy with proteolytic agents.
[On the use of enzyme preparations in the therapy of dental caries with special reference to trypsin]
[The use of trypsin in non-complicated dental caries]
Dental Plaque
Fibronectin fragmentation induced by dental plaque and Bacteroides gingivalis.
[Cooperation of antigens, immunoglobulins, complement and antimicrobial enzymes in the regulation of blood granulocyte locomotion]
Dermatitis
Involvement of Tryptase and Proteinase-Activated Receptor-2 in Spontaneous Itch-Associated Response in Mice With Atopy-like Dermatitis.
Dermatitis, Atopic
Exonic mutations associated with atopic dermatitis disrupt lympho-epithelial Kazal-type related inhibitor action and enhance its degradation.
Multiple pathways are involved in DNA degradation during keratinocyte terminal differentiation.
[Serum trypsin level in patients with atopic dermatitis]
Dermatitis, Contact
Contact sensitivity in the mouse. V. The role of macrophage cytophilic antibody in passive transfer and the effect of trypsin and anti-gamma globulin serum.
Dermatitis, Phototoxic
Enhanced susceptibility to HPD-sensitized phototoxicity and correlated resistance to trypsin detachment in SV40 transformed IMR-90 cells.
Dermatomycoses
Comparison of trypsin treatment method and standard laboratory technique for diagnosis of dermatomycosis.
Diabetes Mellitus
Absence of association between SPINK1 trypsin inhibitor mutations and Type 1 or 2 diabetes mellitus in India and Germany.
Exocrine pancreatic function in diabetes mellitus.
Impaired activity of serum alpha-1-antitrypsin in diabetes mellitus.
Low serum amylase, lipase, and trypsin as biomarkers of metabolic disorders: A systematic review and meta-analysis.
Non enzymatic glycosylation of alpha-1-proteinase inhibitor of human plasma.
Plasma inactive renin in patients with diabetes mellitus: effects of standing and the relation to serum protease inhibitor.
Serum isoamylase activities in diabetes mellitus.
Serum trypsin concentrations in diabetes mellitus.
Trypsin in the treatment of local complications of peripheral vascular disease in diabetes mellitus.
[Activity of serum and lymphocyte serine proteases of patients with diabetes mellitus and the possibility of using protease blockers in combined therapy]
[Clinical significance of urinary excretion of pancreatic secretory trypsin inhibitor in the diagnosis of diabetes mellitus]
[Trypsin deficiency in diabetes mellitus of children and adolescents (author's transl)]
[Use of pancreozymin for detection of pancreatic enzyme-secreting insufficiency in diabetic patients and selection of methods of treatment]
Diabetes Mellitus, Experimental
[Characteristics of the course of alloxan diabetes in rats with various methods of isografting the islands of Langerhans]
Diabetes Mellitus, Type 1
Autoantibodies to IA-2 and IA-2 beta in insulin-dependent diabetes mellitus recognize conformational epitopes: location of the 37- and 40-kDa fragments determined.
Distinct antibody specificities to a 64-kD islet cell antigen in type 1 diabetes as revealed by trypsin treatment.
Exocrine pancreatic function in insulin-dependent diabetes mellitus.
Impaired activity of serum alpha-1-antitrypsin in diabetes mellitus.
Pancreatic exocrine and endocrine events occur concomitantly but independently during the course of fulminant type 1 diabetes.
Prevention of murine EAE by oral hydrolytic enzyme treatment.
Serum trypsin concentration and pancreatic trypsin secretion in insulin-dependent diabetes mellitus.
The 37/40-kilodalton autoantigen in insulin-dependent diabetes mellitus is the putative tyrosine phosphatase IA-2.
[Trypsin deficiency in diabetes mellitus of children and adolescents (author's transl)]
Diabetes Mellitus, Type 2
ACID- AND HEAT-STABLE TRYPSIN INHIBITORY PEPTIDE FROM THE VISCERA OF JAPANESE COMMON SQUID (TODARODES PACIFICUS)
Comparison of the effects of ramipril versus telmisartan in reducing serum levels of high-sensitivity C-reactive protein and oxidized low-density lipoprotein cholesterol in patients with type 2 diabetes mellitus.
Concentration of leukocyte elastase in plasma and polymorphonuclear neutrophil extracts in type 2 diabetes.
Development of a method for urine bikunin/urinary trypsin inhibitor (UTI) quantitation and structural characterization: Application to type 1 and type 2 diabetes.
Levels of Urinary Trypsin Inhibitor and Structure of Its Chondroitin Sulphate Moiety in Type 1 and Type 2 Diabetes.
Low serum amylase, lipase, and trypsin as biomarkers of metabolic disorders: A systematic review and meta-analysis.
[Hypotrypsinemia in diabetes mellitus]
Diabetes, Gestational
Serum trypsin inhibitory capacity in normal pregnancy and gestational diabetes mellitus.
Diabetic Cardiomyopathies
Exposure of cardiomyocytes to angiotensin II induces over-activation of monoamine oxidase type A: Implications in heart failure.
Diabetic Foot
[Molecular Characterization of Lucimycin Gene of Lucilia sericata].
Diabetic Nephropathies
An inhibition of urinary albumin excretion by protease inhibitor in streptozotocin-diabetic rats.
Diabetic Retinopathy
Integrin overexpression induced by high glucose and by human diabetes: potential pathway to cell dysfunction in diabetic microangiopathy.
TGR5 receptor activation attenuates diabetic retinopathy through suppression of RhoA/ROCK signaling.
Vascular wall von Willebrand factor in human diabetic retinopathy.
Diphtheria
Cloned diphtheria toxin fragment A is expressed from the tox promoter and exported to the periplasm by the SecA apparatus of Escherichia coli K12.
Cytotoxicity of a recombinant ricin-A-chain fusion protein containing a proteolytically-cleavable spacer sequence.
Diphtheria toxin receptor. Identification of specific diphtheria toxin-binding proteins on the surface of Vero and BS-C-1 cells.
Isolation and characterization of the cyanogen bromide peptides from the B fragment of diphtheria toxin.
Isolation and properties of the trypsin-derived ADP-ribosyl peptide from diphtheria toxin-modified yeast elongation factor 2.
Localization of the active site of diphtheria toxin.
PURIFICATION AND CRYSTALLIZATION OF DIPHTHERIA ANTITOXIN.
Specific cleavage of diphtheria toxin by human urokinase.
Structure and activity of diphtheria toxin. II. Attack by trypsin at a specific site within the intact toxin molecule.
The pH-dependent conformational change of diphtheria toxin.
[PARTIAL PURIFICATION OF DIPHTHERIA TOXOID BY TRYPSIN.]
[Specificity of antibodies to diphtheria toxin subunits in children with various forms of diphtheria infections]
Diphyllobothriasis
[Inhibitors of proteolytic enzymes in the blood serum of patients with diphyllobothriasis]
Discitis
[Value of the assay of protein SAA and urinary antitrypsin activity in osteoarticular infections]
Disseminated Intravascular Coagulation
Gabexate mesylate inhibition of serine proteases: thermodynamic and computer-graphics analysis.
Protective effects of urinary trypsin inhibitor on systemic inflammatory response induced by lipopolysaccharide.
Protective role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide.
Protective role of urinary trypsin inhibitor in lung expression of proinflammatory cytokines accompanied by lethal liver injury in mice.
Trypsin-like activity and thromboxane release in adult respiratory distress syndrome.
Urinary trypsin inhibitor as a therapeutic option for endotoxin-related inflammatory disorders.
Urinary trypsin inhibitor attenuates liver enzyme elevation after liver resection.
Urinary trypsin inhibitor protects against liver injury and coagulation pathway dysregulation induced by lipopolysaccharide/D-galactosamine in mice.
Urinary trypsin inhibitor protects against systemic inflammation induced by lipopolysaccharide.
[Acute pancreatitis in dogs. A literature study]
[Pi phenotypes of alpha-1-antitrypsin and antiproteases in meningococcal sepsis]
Donohue Syndrome
Mechanisms of insulin resistance in cultured fibroblasts from a patient with leprechaunism: resistance to proteolytic activation of glycogen synthase by trypsin.
Dry Socket
A report on the use of crystalline trypsin in treatment of alveolar osteitis.
Alveolitis sicca dolorosa (dry socket): frequency of occurrence and treatment with trypsin.
Effect of local application of trypsin on postextraction alveolar osteitis.
Duodenal Ulcer
Elevated pancreatic secretory trypsin inhibitor levels during severe inflammatory disease, renal insufficiency, and after various surgical procedures.
Response to jejunal acidification in man. II. Pancreatic, biliary and gastric responses.
The effects of highly selective vagotomy on exocrine pancreatic function in man.
[Relationship between the activity of trypsin and trypsin inhibitors in duodenal ulcer]
Duodenogastric Reflux
Clinical relevance of gastroduodenal dysfunction in reflux esophagitis.
Duodenogastric reflux in children: measurement of phospholipids and trypsin in gastric content.
Esophageal barrier function and tight junction expression in healthy subjects and patients with gastroesophageal reflux disease: functionality of esophageal mucosa exposed to bile salt and trypsin in vitro.
Prevention of experimental acute pancreatitis by intraduodenal trypsin inhibitor in rat.
Studies on experimental animals involving surgical procedures and/or nitrosamine treatment related to the etiology of esophageal adenocarcinoma.
Trypsin induces biphasic muscle contraction and relaxation via transient receptor potential vanilloid 1 and neurokinin receptors 1/2 in porcine esophageal body.
[Evaluation of the intensity of the duodenogastric reflux based on the alkaline phosphatase and trypsin activities in the stomach contents]
Dysgerminoma
Elevated serum inhibin and tumor-associated trypsin inhibitor concentrations in a young woman with dysgerminoma of the ovary.
Dyskinesias
Altered Expression of Brain Proteinase-Activated Receptor-2, Trypsin-2 and Serpin Proteinase Inhibitors in Parkinson's Disease.
Dyslipidemias
Anti-TNF-? Agent Tamarind Kunitz Trypsin Inhibitor Improves Lipid Profile of Wistar Rats Presenting Dyslipidemia and Diet-induced Obesity Regardless of PPAR-? Induction.
Echinococcosis
[Cure of five hydatid cysts of the lungs by bronchial aspiration; contribution of the adjuvant methods: varidase, trypsin, papain, ultra-sound.]
Eczema
Latency and duration of pruritus elicited by trypsin in aged patients with itching eczema and psoriasis.
[Differential diagnostic importance of intracutaneous trypsin injections in endogenous eczema]
Egg Hypersensitivity
Monoclonal antibodies against hen's egg ovomucoid.
Elliptocytosis, Hereditary
Molecular basis of Sp alpha I/65 hereditary elliptocytosis in North Africa: insertion of a TTG triplet between codons 147 and 149 in the alpha-spectrin gene from five unrelated families.
Embolism, Air
[A case of spontaneous pneumothorax with gas embolism in intratracheal trypsin instillation]
[Spontaneous pneumothorax with gas embolism during intratracheal administration of trypsin]
Embolism, Fat
The Protective Roles of Urinary Trypsin Inhibitor in Brain Injury Following Fat Embolism Syndrome in a Rat Model.
Empyema
[Treatment of empyema with trypsin, with special reference to thoracic surgery.]
Empyema, Pleural
[Chronic pleural empyema favorably resolved with trypsin in situ.]
[Enzymatic therapy of the pleural empyema with special reference to the results of trypsin therapy.]
[Irrigation of tuberculous and mixed pleural empyema with trypsin solution (pyosalv).]
[Therapeutic use of trypsin as a matter of principle in the pleural empyema treatment.]
[Use of trypsin, streptokinase, and streptodornase in thoracic empyema.]
Encephalitis
Identification of trypsin I as a candidate for influenza A virus and Sendai virus envelope glycoprotein processing protease in rat brain.
The effects of trypsin on rat brain astrocyte activation.
Encephalitis, Japanese
Architecture of the flaviviral replication complex. Protease, nuclease, and detergents reveal encasement within double-layered membrane compartments.
Japanese encephalitis virus NS2B-NS3 protease binding to phage-displayed human brain proteins with the domain of trypsin inhibitor and basic region leucine zipper.
Organization of flaviviral replicase proteins in virus-induced membranes: a role for NS1' in Japanese encephalitis virus RNA synthesis.
Encephalitis, Tick-Borne
Changing the protease specificity for activation of a flavivirus, tick-borne encephalitis virus.
Immunogenicity of tick-borne encephalitis virus glycoprotein fragments: epitope-specific analysis of the antibody response.
The flavivirus envelope protein E: isolation of a soluble form from tick-borne encephalitis virus and its crystallization.
[Amino acid sequence of various tryptic peptides of the envelope protein of the tick-borne encephalitis virus]
Encephalomyelitis
Experimental autoimmune encephalomyelitis. Digestion of basic protein of human myelin with cyanogen bromide and trypsin.
In vitro study on the immunological effect of bromelain and trypsin on mononuclear cells from humans.
Morphological and biochemical studies on experimental allergic encephalomyelitis in inbred lines of chickens.
Purification of mouse encephalomyelitis virus (GDVII virus) by means of ether extraction, acetone precipitation, trypsin digestion, and hemagglutination.
The effect of trypsin on hemagglutination by murine encephalomyelitis virus (GDVII).
Trypsin-sensitive neutralization site on VP1 of Theiler's murine encephalomyelitis viruses.
Encephalomyelitis, Autoimmune, Experimental
Experimental autoimmune encephalomyelitis. Digestion of basic protein of human myelin with cyanogen bromide and trypsin.
Observations on the effects of protease inhibitors on the suppression of experimental allergic encephalomyelitis.
Encephalomyelitis, Enzootic Porcine
[The stabilizing and reactivating influence of trypsin on the virus of Teschen disease (swine paralysis) and inactivation of foot and mouth disease virus by this enzyme.]
Endometrial Neoplasms
Characterization of a 54 kDa, alpha 1-antitrypsin-like protein isolated from ascitic fluid of an endometrial cancer patient.
Effect of intracavitary radiotherapy on tumor-associated trypsin inhibitor (TATI) in patients with cervical and endometrial cancer.
Monitoring the treatment outcome in endometrial cancer patients by CEA and TATI.
TATI (tumor associated trypsin inhibitor) and cancer antigen 125 (CA 125) in patients with early-stage endometrial cancer.
Tumor-associated trypsin inhibitor in patients with endometrial cancer.
Endometriosis
Protein, progesterone, and protease inhibitors in uterine and peritoneal fluids of women with endometriosis.
Serum levels of the tumour-associated trypsin inhibitor in patients with endometriosis.
Enteritis
Acute radiation enteritis in rats: bile salts and trypsin.
Effect of trypsin inhibitor activity in soya bean on growth performance, protein digestibility and incidence of sub-clinical necrotic enteritis in broiler chicken flocks.
Effects of Clostridium perfringens beta-toxin on the rabbit small intestine and colon.
Effects of diets containing soybean meal on trypsin mRNA expression and activity in Atlantic salmon (Salmo salar L).
Pigbel in Papua New Guinea: an ancient disease rediscovered.
Proteinase-activated receptor-2: two potential inflammatory mediators of the gastrointestinal tract in Atlantic salmon.
Significance of beta 2-toxigenic clostridium perfringens infections in animals and their predisposing factors--a review.
The pigbel story of Papua New Guinea.
Enterocolitis
[Activity of trypsin, its inhibitors and antiinhibitors in blood serum of patients with chronic colitis and enterocolitis]
[State of the external secretory function of the pancreas in chronic enterocolitis]
enteropeptidase deficiency
Isolated congenital enterokinase deficiency. Recent findings and review of the literature.
Rapid semiquantitative tests for trypsin and chymotrypsin application to screening for cystic fibrosis, enterokinase deficiency and pancreatic hypoplasia in neonates.
The interrelationship of enterokinase and trypsin activities in intractable diarrhea of infancy, celiac disease, and intravenous alimentation.
Eosinophilia
Effects of a reversible beta-tryptase and trypsin inhibitor (RWJ-58643) on nasal allergic responses.
Epilepsy
A regulatory role for protease-activated receptor-2 in motivational learning in rats.
Equine Infectious Anemia
Physicochemical studies of equine infectious anemia virus. II. Sensitivity of the virus to trypsin.
Reversible staining and peptide mapping of proteins transferred to nitrocellulose after separation by sodium dodecylsulfate-polyacrylamide gel electrophoresis.
Esophageal Neoplasms
[Responses of cytokines, acute phase proteins, and polymorphonuclear cell elastase to surgical stress in the patients with esophageal cancer]
Esophageal Squamous Cell Carcinoma
Association of trypsin expression with recurrence and poor prognosis in human esophageal squamous cell carcinoma.
Sporamin suppresses growth of human esophageal squamous cell carcinoma cells by inhibition of NF??B via an AKT?independent pathway.
Esophagitis
Clinical relevance of gastroduodenal dysfunction in reflux esophagitis.
Effect of sodium polyacrylate on chronic reflux esophagitis in rats.
Evaluation and surgical correction of esophagitis after partial gastrectomy.
Experimental esophagitis in a rabbit model. Clinical relevance.
Interleukin-8 production via protease-activated receptor 2 in human esophageal epithelial cells.
Role of bile salts and trypsin in the pathogenesis of experimental alkaline esophagitis.
Role of pancreatic trypsin in chronic esophagitis induced by gastroduodenal reflux in rats.
Role of the components of the gastroduodenal contents in experimental acid esophagitis.
Taurodeoxycholate modulates the effects of pepsin and trypsin in experimental esophagitis.
Trypsin activity and bile acid concentrations in the esophagus after distal gastrectomy.
Esophagitis, Peptic
Alkaline esophagitis: a comparison of the ability of components of gastroduodenal contents to injure the rabbit esophagus.
Bile acids and trypsin are unimportant in alkaline esophageal reflux.
Contribution of trypsin and cholate to the pathogenesis of experimental alkaline reflux esophagitis.
Effect of bile salts and related compounds on esophageal mucosa.
Morphological alterations in tryptic esophagitis: an experimental light microscopic and scanning and transmission electron microscopic study in rabbits.
Oral trypsin inhibitor can improve reflux esophagitis after distal gastrectomy concomitant with decreased trypsin activity.
Role of bile salts and trypsin in the pathogenesis of experimental alkaline esophagitis.
Role of pancreatic trypsin in chronic esophagitis induced by gastroduodenal reflux in rats.
Taurodeoxycholate modulates the effects of pepsin and trypsin in experimental esophagitis.
[Action of trypsin inhibitors on the development of reflux esophagitis in rats.]
[Effect of FOY-305 on post-operative reflux esophagitis in rats (II). Analysis of mechanism in the pathogenesis of reflux esophagitis after total gastrectomy in rats]
Essential Hypertension
Effectiveness of Sepharose-bound trypsin versus liquid-phase trypsin plus benzamidine for activation of inactive renin in human plasma.
[Comparative evaluation of the efficacy of methods of cryo- and trypsin activation of inactive renin in vitro]
Exocrine Pancreatic Insufficiency
Abnormalities of circulating immunoreactive pancreatic anionic trypsinogen in cystic fibrosis: an assay artifact due to cross-reacting serum antibodies.
Age-related alterations of immunoreactive pancreatic cationic trypsinogen in sera from cystic fibrosis patients with and without pancreatic insufficiency.
Comparative study of serum trypsin levels and pancreatic exocrine function in chronic pancreatitis.
Determination of fecal fat and trypsin output in the evaluation of chronic canine diarrhea.
Enterokinase and trypsin activities in pancreatic insufficiency and diseases of the small intestine.
Enteropancreatic circulation of trypsin in man.
Evaluation of tests of exocrine and endocrine pancreatic function in older patients with cystic fibrosis.
Exocrine pancreatic insufficiency after allogeneic bone marrow transplantation.
Hydrogen breath test with glucose in exocrine pancreatic insufficiency.
Hydrogen breath test with low-dose rice flour for assessment of exocrine pancreatic insufficiency.
Immunoactive trypsins in duodenal juice from children with gastrointestinal disorders.
Immunoreactive serum trypsin in diseases of the pancreas.
Intestinal activities of trypsin, lipase, and phospholipase after a test meal. An evaluation of 474 examinations.
Plasma immunoreactive cationic trypsin(ogen) pattern in reserpinized rat model of cystic fibrosis. Resemblance to humans.
Postprandial cholecystokinin response in patients with chronic pancreatitis in treatment with oral substitutive pancreatic enzymes.
Proteases in the evaluation of pancreatic function and pancreatic disease.
Serum trypsin, alpha-amylase and lipase during bombesin stimulation in normal subjects and patients with pancreatic insufficiency.
Stool trypsin and chymotrypsin. Value in the diagnosis of pancreatic insufficiency in cystic fibrosis.
The noninvasive biochemical diagnosis of gastrointestinal disease, with special reference to children.
Total pancreatic insufficiency in pigs: a model to study intestinal enzymes and plasma levels of digestive hormones after pancreatic supplementation by a whole pancreas preparation.
Tubeless tests of exocrine pancreatic function in patients with cystic fibrosis.
Zinc and copper concentrations in serum, blood and liver in moderate experimental pancreatic insufficiency.
[DETERMINATION OF TRYPSIN AND CHYMOTRYPSIN ACTIVITY IN STOOLS. A SPECIFIC SENSITIVE METHOD FOR THE DEMONSTRATION OF EXOCRINE PANCREATIC INSUFFICIENCY.]
[On the determination of trypsin and chymotrypsin activity in the feces of dogs and their significance in the diagnosis of chronic exocrine pancreatic insufficiency]
[On the treatment of pre- and postoperative pancreatic insufficiency with trypsin inhibitors in patients with gallbladder and stomach diseases.]
[Significance of immunoreactive lipase in the diagnosis of pancreatic diseases]
Fabry Disease
Endocytotic internalization of alpha-2-macroglobulin: alpha-galactosidase conjugate by cultured fibroblasts derived from Fabry hemizygote.
Factor XII Deficiency
Phosphatidylethanolamine participates in the stimulation of the contact system of coagulation by very-low-density lipoproteins.
Fallopian Tube Diseases
[Hydrotubations with trypsin in tubal obstruction.]
Fatty Liver
Cross talk between toll-like receptor-4 signaling and angiotensin-II in liver fibrosis development in the rat model of non-alcoholic steatohepatitis.
Dietary wheat amylase trypsin inhibitors promote features of murine non-alcoholic fatty liver disease.
Dual blockade of angiotensin-II and aldosterone suppresses the progression of a non-diabetic rat model of steatohepatitis.
Therapeutic effects of angiotensin II type 1 receptor blocker, irbesartan, on non-alcoholic steatohepatitis using FLS-ob/ob male mice.
Feline Infectious Peritonitis
Comparative properties of feline coronaviruses in vitro.
Fetal Growth Retardation
Activities of lipase and trypsin in duodenal juice of infants small for gestational age.
Fibrosarcoma
A sarcoma-derived protein regulates hepatocyte metabolism via autocrine production of tumor necrosis factor-alpha.
Hyaluronate appears to be covalently linked to the cell surface.
Onco-embryonic antigens on murine normal adult cells.
Plasminogen activator activity in clonogenic cell populations separated from a murine fibrosarcoma.
Soluble factors from murine and human tumors induce suppressor cells.
Steps involved in activation of the pro-matrix metalloproteinase 9 (progelatinase B)-tissue inhibitor of metalloproteinases-1 complex by 4-aminophenylmercuric acetate and proteinases.
Food Hypersensitivity
Investigations of immunogenic, allergenic and adjuvant properties of Cry1Ab protein after intragastric exposure in a food allergy model in mice.
Foot Ulcer
[Molecular Characterization of Lucimycin Gene of Lucilia sericata].
Foot-and-Mouth Disease
Antibody and host cell recognition of foot-and-mouth disease virus (serotype C) cleaved at the Arg-Gly-Asp (RGD) motif: a structural interpretation.
Antibody response against foot and mouth disease virus (FMDV). Part I: Responses measured in sera of vaccinated steers with complete virus, trypsin treated virus, 12 S virus subunits and heterologous virus.
Antibody response against foot and mouth disease virus (FMDV). Part II: Responses measured in fractionated sera of infected steers with complete virus, trypsin treated virus, 12 S virus subunits, VIA and heterologous virus.
Application of monoclonal antibodies to quality control of foot-and-mouth disease vaccines.
Effect of trypsin and chymotrypsin on the polypeptides of large and small plaque variants of foot-and-mouth disease virus: relationship to specific antigenicity and infectivity.
Effect of trypsin treatment on the antigenic characteristics of plaque variants of type-O 1 and type Asia-1 foot-and-mouth disease viruses.
Foot-and-mouth disease virus: immunogenicity and structure of fragments derived from capsid protein VP and of virus containing cleaved VP.
Immunoreactivity and trypsin sensitivity of recombinant virus-like particles of foot-and-mouth disease virus.
Nature of the inactivating action of trypsin on foot-and-mouth disease virus.
Ribonuclease contamination of crystalline deoxyribonclease, trypsin, and of partially purified foot-and-mouth disease virus preparations.
STUDIES IN ULTRAFILTRATION.
Type-independent detection of foot-and-mouth disease virus by monoclonal antibodies that bind to amino-terminal residues of capsid protein VP2.
[The stabilizing and reactivating influence of trypsin on the virus of Teschen disease (swine paralysis) and inactivation of foot and mouth disease virus by this enzyme.]
Fowlpox
An interferon-gamma-binding protein of novel structure encoded by the fowlpox virus.
Fusariosis
[Response of corn plants to the effect of salicylic acid and Fusarium moniliforme]
Galactosemias
Aldose reductase inhibition fails to prevent retinopathy in diabetic and galactosemic dogs.
Response of capillary cell death to aminoguanidine predicts the development of retinopathy: comparison of diabetes and galactosemia.
Gallbladder Neoplasms
Secretion of pancreatic secretory trypsin inhibitor by cultured human carcinoma cells.
Gallstones
A new experimental model for gallstone pancreatitis: short-termed pancreatico-biliary duct obstruction and exocrine stimulation with systemic hypotension in rats.
A possible mechanism for gallstone pancreatitis: repeated short-term pancreaticobiliary duct obstruction with exocrine stimulation in rats.
Acid stable trypsin inhibitor in bile.
Trypsin level in gallbladder bile and ductitis and width of the cystic duct.
Ganglion Cysts
[Experimental study of primary culture methods for spiral ganglion cells of newborn rats]
Gastric Fistula
The role of gastric secretion in post-diverted pancreatic hypersecretion in conscious rats.
Gastritis
[Evaluation of the intensity of the duodenogastric reflux based on the alkaline phosphatase and trypsin activities in the stomach contents]
Gastritis, Atrophic
Progastrin processing during antral G-cell hypersecretion in humans.
Gastroenteritis
Isolation of group A human rotaviruses from faecal specimens in monkey MA-104 cells.
Isolation of human rotaviruses in primary cultures of monkey kidney cells.
Isolation of transmissible gastroenteritis virus from feces of diarrheic pigs in roller culture of CPK cells in the presence of trypsin.
Plaque quantitation and virus neutralization assays for human astroviruses.
The multiplication of transmissible gastroenteritis viruses in several cell lines originated from porcine kidney and effects of trypsin on the growth of the viruses.
The participation of antibody in spontaneous and antibody-dependent cell-mediated cytotoxicity in the pig.
Three human rotavirus serotypes demonstrated by plaque neutralization of isolated strains.
[Isolation of a concentrated purified preparation of the transmissible gastroenteritis virus of swine and a study of its antigenic properties]
Gastroesophageal Reflux
Bile acids and trypsin are unimportant in alkaline esophageal reflux.
Esophageal barrier function and tight junction expression in healthy subjects and patients with gastroesophageal reflux disease: functionality of esophageal mucosa exposed to bile salt and trypsin in vitro.
Oral trypsin inhibitor can improve reflux esophagitis after distal gastrectomy concomitant with decreased trypsin activity.
Trypsin impaired epithelial barrier function and induced IL-8 secretion through basolateral PAR-2: a lesson from a stratified squamous epithelial model.
Trypsin induces biphasic muscle contraction and relaxation via transient receptor potential vanilloid 1 and neurokinin receptors 1/2 in porcine esophageal body.
Gastrointestinal Diseases
Serum elastase 1 in inflammatory pancreatic and gastrointestinal diseases and in renal insufficiency. A comparison with other serum pancreatic enzymes.
[Determination of tumor-associated trypsin inhibitor (TATI) in subjects with gastrointestinal diseases. Preliminary data]
[Immunoreactive trypsin in the serum of normal children and children with gastrointestinal diseases]
Gastrointestinal Neoplasms
Autocrine extra-pancreatic trypsin 3 secretion promotes cell proliferation and survival in esophageal adenocarcinoma.
The measurement of serum immunoreactive pancreatic secretory trypsin inhibitor in gastrointestinal cancer and pancreatic disease.
Tumor-associated trypsin inhibitor, TATI, in gastrointestinal cancer and related benign diseases.
Gastroschisis
Intra-amniotic administration of urinary trypsin inhibitor preserves intestinal contractility in meconium induced intestinal damage in chick embryos with gastroschisis.
Urinary trypsin inhibitor present in fetal urine prevents intraamniotic meconium-induced intestinal damage in gastroschisis.
Genetic Diseases, Inborn
A mouse model of hereditary pancreatitis generated by transgenic expression of R122H trypsinogen.
An overview of hereditary pancreatitis.
Mechanisms of intracellular zymogen activation.
Was Ugo Foscolo (1778-1827) affected by alpha-1 antitrypsin deficiency?
[Significance of trypsinogen gene mutations in the etiology of hereditary pancreatitis]
Giant Axonal Neuropathy
Characterization of the intermediate filament apparatus in skin fibroblasts from patients with giant axonal neuropathy: effect of trypsin.
Giant Cell Tumors
Response to hormones of cells cultured from human giant cell tumors of bone.
[Purification and study of the characteristics of the multinucleated giant cells of the giant cell tumor]
Gingival Pocket
[Increase in the sensitivity of the microflora of pathological gingival pockets to streptomycin under the influence of dimexide and trypsin]
Gingivitis
Adhesion of Porphyromonas gingivalis fimbriae to human gingival cell line Ca9-22.
[Application of lyophilized trypsin in treatment of dry alveolus and ulcerative gingivitis]
Glaucoma
[Studies on pathological changes in cases of the aged retinal vessels, hypertension, and absolute glaucoma with the trypsin digestion method]
Glioblastoma
A novel developmentally regulated gene in lung mesenchyme: homology to a tumor-derived trypsin inhibitor.
cDNA cloning of a novel trypsin inhibitor with similarity to pathogenesis-related proteins, and its frequent expression in human brain cancer cells.
Pretreatment with protease is a useful experimental strategy for enhancing adenovirus-mediated cancer gene therapy.
Production of amyloid beta protein precursor as a proteinase inhibitor by human astrocytic tumors.
Protease pretreatment increases the efficacy of adenovirus-mediated gene therapy for the treatment of an experimental glioblastoma model.
Purification and identification of a novel and four known serine proteinase inhibitors secreted by human glioblastoma cells.
Glioma
A monoclonal antibody recognising the site of limited proteolysis of protein kinase C. Inhibition of down-regulation in vivo.
A software application for comparing large numbers of high resolution MALDI-FTICR MS spectra demonstrated by searching candidate biomarkers for glioma blood vessel formation.
Cell-Matrix De-Adhesion Dynamics Reflect Contractile Mechanics.
Golgi phosphoprotein 3 sensitizes the tumour suppression effect of gefitinib on gliomas.
Heterogeneity of dipeptidyl peptidase IV from C6 rat glioma cells.
Inhibition by trypsin of the high-affinity acidic amino acid transport system in C6 glioma cells.
Interleukin-2 and lymphokine activated killer (LAK) cells in the treatment of malignant glioma: clinical and experimental studies.
Lymphokine activated killer (LAK) cell mediated killing of human glioma: effect of pretreating glioma with various membrane modifying agents.
Lymphokine activated killer (LAK) cell-mediated lysis of murine glioma: trypsin-chymotrypsin-sensitive glioma protein is responsible for tumor-selective recognition by LAK cells.
Optimized dissociation protocol for isolating human glioma stem cells from tumorspheres via fluorescence-activated cell sorting.
Trypsin promotes C6 glioma cell proliferation in serum- and growth factor-free medium.
Glomerulonephritis
Analyses of IgA1 hinge glycopeptides in IgA nephropathy by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Direct evidence for decreased sialylation and galactosylation of human serum IgA1 Fc O-glycosylated hinge peptides in IgA nephropathy by mass spectrometry.
Experimental glomerulonephritis induced by minimal doses of trypsin.
Immunohistochemical detection of immunoglobulins and complements in formaldehyde-fixed and paraffin-embedded renal biopsy tissues; an adjunct for diagnosis of glomerulonephritis.
Rapid accumulation of plasma acid-stable trypsin inhibitor in experimental acute renal injury.
Studies of trypsin inhibitor in urine. IV. The trypsin inhibitor in urine and serum of rabbits experimentally infected with streptococcus resulting in glomerulonephritis.
Urinary UK, t-PA and urinary trypsin inhibitor in health and glomerular diseases.
[Affinity sorbents with tripeptide morpholine ligands for isolation of proteases]
[Development of an immunoenzyme method for the quantitative determination of an acid-stable trypsin inhibitor in urine: use for assessing the severity of glomerulonephritis]
[Experimental glomerulonephritis induced by a new method. VII. On the nephrotoxin absorption activity common to ultrasupernatants of trypsin digestion in various tissue homogenates.]
[EXPERIMENTAL GLOMERULONEPHRITIS INDUCED BY A NEW PROCEDURE. X. ON THE ANTIGENICITY (NEPHROTOXIC ACTIVITY) OF THE ULTRASUPERNATANT OF KIDNEY TISSUE HOMOGENATE TREATED WITH TRYPSIN.]
[Trypsin inhibitor in the urine of patients with glomerulonephritis]
Glomerulonephritis, IGA
Direct evidence for decreased sialylation and galactosylation of human serum IgA1 Fc O-glycosylated hinge peptides in IgA nephropathy by mass spectrometry.
Increase of IgA-bearing lymphocytes in peripheral blood from patients with IgA nephropathy.
Glomerulonephritis, Membranoproliferative
Immunohistochemical detection of immunoglobulins and complements in formaldehyde-fixed and paraffin-embedded renal biopsy tissues; an adjunct for diagnosis of glomerulonephritis.
Glycosuria
The Treatment of Glycosuria by Trypsin and Secretin.
Gonadal Dysgenesis
Short-arm deletion of an X chromosome (45,XO/46,XX p--).
Gout
A case report of acute pancreatitis with glycogen storage disease type IA in an adult patient and review of the literature.
Granuloma
Characteristics of glucocorticoid-binding by inflammatory tissue of rats.
Collagenase, elastase, and nonspecific protease production by vigorous or immunomodulated liver granulomas and granuloma macrophages/eosinophils of S mansoni-infected mice.
Effect of some clinically used proteolytic enzymes on inflammation in rats.
Effect of trypsin and chymotrypsin on the granuloma pouch.
Granulomatosis with Polyangiitis
Alpha 1-antitrypsin activity is markedly decreased in Wegener's granulomatosis.
Graves Disease
A microcytotoxicity assay for thyroid-specific cytotoxic antibody, antibody-dependent cell-mediated cytotoxicity and direct lymphocyte cytotoxicity using human thyroid cells.
Head and Neck Neoplasms
Squamous cell carcinoma antigen (SCC), carcinoembryonic antigen (CEA), and tumour-associated trypsin inhibitor (TATI) for monitoring head and neck cancer.
Heart Arrest
Insufficient production of urinary trypsin inhibitor for neutrophil elastase release after cardiac arrest.
Neuroprotection of ulinastatin on transient cerebral ischemia via antioxidative mechanisms.
Heart Diseases
Assessment of antibody mediated cytolysis of adult cardiocytes isolated by centrifugation in a continuous gradient of Percoll in patients with acute myocarditis.
Comparison of the chemical composition and nutritional value of Amaranthus cruentus flour and its protein concentrate.
Furazolidone-induced cardiomyopathy in turkeys. Association with a relative alpha1-antitrypsin deficiency.
Hepatitis, cardiomyopathy and hemodynamics in furazolidone-induced round heart disease of turkeys.
Turkey serum trypsin inhibitors: description and characterization.
Heart Failure
Analysis of circulating forms of proBNP and NT-proBNP in patients with severe heart failure.
Effect of eplerenone, a selective aldosterone blocker, on blood pressure, serum and macrophage oxidative stress, and atherosclerosis in apolipoprotein E-deficient mice.
Pharmacokinetics of irbesartan are not altered in special populations.
Hematologic Diseases
[Studies on immunity tests with Rh-sensitized and papain and trypsin treated erythrocytes in blood diseases.]
Hematologic Neoplasms
Combination assay of urinary free L-fucose and trypsin inhibitor may be useful indicators of disease activity in patients with hematologic malignancies.
Hematoma, Subdural
Early changes of arginine vasopressin and angiotensin II in patients with acute cerebral injury.
Hematuria
Effects of Hematuria on the Proteomic Profile of Urinary Extracellular Vesicles: Technical Challenges.
Hemophilia A
Effect of standardization and normalization on imprecision of calibrated automated thrombography: an international multicentre study.
Global coagulation assays in hemophilia A: A comparison to conventional assays.
Microfluidic hemophilia models using blood from healthy donors.
Thrombin generation and bleeding in haemophilia A.
Trypsin clotting time (K-test) in hemophilia A and in hemophilia B1.
Hemophilia B
Microfluidic hemophilia models using blood from healthy donors.
Trypsin clotting time (K-test) in hemophilia A and in hemophilia B1.
Hemothorax
[Action of trypsin in traumatic hemothorax. Experimental control.]
[Utilization of trypsin in treatment of hemothorax; preliminary report.]
Hepatitis
High prevalence of alpha 1 antitrypsin phenotypes in viral hepatitis B infected patients in Iran.
Mouse hepatitis virus immunofluorescence in formalin- or Bouin's-fixed tissues using trypsin digestion.
Overexpression of tumor-associated trypsin inhibitor (SPINK1/TATI) in hepatitis C-associated hepatocellular carcinoma: potential implications for viral hepatocarcinogenesis.
Serum pancreatic enzyme alterations in acute viral hepatitis.
Serum trypsin inhibitory activity and alpha-1-antitrypsin level in liver diseases.
Urinary and serum trypsin inhibitors in viral hepatitis.
Wedelolactone from Vietnamese Eclipta prostrata (L) L. Protected Zymosan-induced shock in Mice.
[Concentration and activity of alpha-1-antitrypsin in neonatal hepatitis]
[Effect of a trypsin and kallikrein inactivator in MHV3 induced experimental hepatitis in mice]
[Effect of trypsin on the course of viral hepatitis and blood levels of various biochemical indicators]
[Immunoreactive trypsin in the serum of normal children and children with gastrointestinal diseases]
[Increasing of the trypsin rate frequency in the blood serum in children with viral hepatitis].
[RESEARCH ON THE ACTION OF A KALLIKREIN AND TRYPSIN INHIBITOR ON THE COURSE OF EXPERIMENTAL HEPATITIS OF THE MOUSE DUE TO MHV-3.]
Hepatitis A
Protease digestion of hepatitis A virus: disparate effects on capsid proteins, antigenicity, and infectivity.
The unique role of domain 2A of the hepatitis A virus precursor polypeptide P1-2A in viral morphogenesis.
Hepatitis B
Expression of the pancreatic secretory trypsin inhibitor gene in the liver infected with hepatitis B virus.
Increased Serum Levels of Trypsin Inhibitor Kazal1 in Patients with HBV-Related Hepatocellular Carcinoma Predict a Poor Prognosis.
Tryptic cleavage of antibody binding sites from hepatitis B surface antigen particles.
Hepatitis C
Characterization of engineered hepatitis C virus NS3 protease inhibitors affinity selected from human pancreatic secretory trypsin inhibitor and minibody repertoires.
Use of a novel washing method combining multiple density gradients and trypsin for removing human immunodeficiency virus-1 and hepatitis C virus from semen.
Hepatitis C, Chronic
Effects of six months losartan administration on liver fibrosis in chronic hepatitis C patients: a pilot study.
Examination of changes in TGF-beta1 and KL-6 expression over time in patients with chronic hepatitis C by AT-II receptor blocker therapy.
Hepatitis E
Meeting Report: 2013 PDA Virus & TSE Safety Forum.
Hepatitis, Chronic
Expression of the pancreatic secretory trypsin inhibitor gene in the liver infected with hepatitis B virus.
Serum trypsin inhibitory activity and alpha-1-antitrypsin level in liver diseases.
[Activity of serum trypsin in patients with chronic hepatitis and liver cirrhosis as an index of extrasecretory function of the pancreas]
[Evaluation of the vegetable oil taken up into the duodenum as a factor in pancreozymin liberation in healthy persons and in digestive organ diseases]
[Levels of serum immunoreactive trypsin in children with intra- and extrahepatic cholestasis]
[The effect of heterologous duodenal content on the motor activity of the duodenum]
Hepatoblastoma
Release of pancreatic secretory trypsin inhibitor from human hepatoblastoma cells on stimulation with cytokines.
Response to IL-6 stimulation of human hepatoblastoma cells: production of pancreatic secretory trypsin inhibitor.
Herpes Labialis
Studies on human epidermal Langerhans' cells: II. Activation of human T lymphocytes to herpes simplex virus.
Herpes Simplex
Disulfide bonds of herpes simplex virus type 2 glycoprotein gB.
Non-phospholipid vesicles as carriers for peptides and proteins: production, characterization and stability studies.
Potential use of Atlantic cod trypsin in biomedicine.
Studies on the attachment of herpes simplex virus. Effect of trypsin treatment.
Study of cell surface antigens induced by herpes simplex virus. Note II. Some properties of the antigens.
The unique N terminus of the herpes simplex virus type 1 large subunit is not required for ribonucleotide reductase activity.
Herpes Zoster
A homologue of pancreatic trypsin is localized in the acrosome of mammalian sperm and is released during acrosome reaction.
A survey of the effects of proteases and glycosidases on culture of rabbit morulae to blastocysts.
Blocking of human sperm-zona interaction by monoclonal antibodies to a glycoprotein family (ZP4) of porcine zona pellucida.
Boar spermadhesin PSP-II: location of posttranslational modifications, heterodimer formation with PSP-I glycoforms and effect of dimerization on the ligand-binding capabilities of the subunits.
Characteristics of monoclonal antibodies against porcine zona pellucida-3 and their functional relevance.
Characterization of antigenic determinants on porcine zona pellucida-3 beta(ZP3 beta) glycoprotein by monoclonal antibodies.
Characterization of the mouse sperm plasma membrane zona-binding site sensitive to trypsin inhibitors.
Chromosome analysis of Murrah buffalo (Bubalus bubalis ) spermatozoa using zona-free hamster oocytes.
Collagenase as an agent for dissolving the zona pellucida of hamster and mouse oocytes.
Cytogenetic analysis of sperm nucleous components of iranian normal and sub-fertile individuals using zona free hamster oocytes.
Development and viability of bovine preimplantation embryos after the in vitro infection with bovine herpesvirus-1 (BHV-1): immunocytochemical and ultrastructural studies.
Development in vitro of investment-free marsupial embryos during cleavage and early blastocyst formation.
Effect of a rat uterine fluid endopeptidase on lysis of the zona pellucida.
Effect of aging and cold temperature storage of hamster ova as assessed in the sperm penetration assay.
Effect of azorellanone, a diterpene from Azorella yareta Hauman, on human sperm physiology.
Effects of the oviduct and wheat germ agglutinin on enzymatic digestion of porcine zona pellucidae.
Embryo transfer as a means of controlling the transmission of viral infections. II. The in vitro exposure of preimplantation bovine embryos to infectious bovine rhinotracheitis virus.
Embryo transfer as a means of controlling the transmission of viral infections. XI. The in vitro exposure of bovine and porcine embryos to vesicular stomatitis virus.
Evidence for a role of the major glycoprotein in the structural maintenance of the pig zona pellucida.
Evidence for the involvement of a species-specific embryonic protease in zona escape of hamster blastocysts.
Exposure of bovine embryos to trypsin during washing does not decrease embryonic survival.
Factors affecting the trypsin induced release of aldosterone in rat adrenal zona glomerulosa tissue.
Generation and characterization of monoclonal antibodies to porcine zona pellucida-3 alpha glycoprotein.
Glycosylated boar spermadhesin AWN-1 isoforms. Biological origin, structural characterization by lectin mapping, localization of O-glycosylation sites, and effect of glycosylation on ligand binding.
Human spermatozoa attach to trypsin-treated hamster zonae pellucidae but do not undergo acrosome reactions.
Identification of a secondary sperm receptor in the mouse egg zona pellucida: role in maintenance of binding of acrosome-reacted sperm to eggs.
Immunologic evidence for addition of oviductal components to the hamster zona pellucida.
Immunological interference with fertilization.
Inhibition of acrosin activity with a trypsin inhibitor blocks human sperm penetration of the zona pellucida.
Inhibition of the acrosome reaction by trypsin inhibitors and prevention of penetration of spermatozoa through the human zona pellucida.
Investigation of some antimicrobial procedures on the in vitro development of early murine embryos aimed toward developing methods for the disinfection of mammalian embryos prior to transfer.
Involvement of trypsin-like activity in binding of mouse spermatozoa to zonae pellucidae.
Limited and specific proteolysis of the zona pellucida by acrosin.
Localization of epitopes for monoclonal antibodies at the N-terminus of the porcine zona pellucida glycoprotein pZPC.
Mating-induced cumulus-oocyte maturation in the shrew, Suncus murinus.
Maturation of hamster oocytes under chemically defined conditions and sperm penetration through the zona pellucida.
Normal penetration of rabbit spermatozoa through a trypsin- and acrosin-resistant zona pellucida.
PH-20 but not acrosin is involved in sperm penetration of the macaque zona pellucida.
Preservation of hamster oocytes to assay the fertilizing capacity of human spermatozoa.
Production of piglets after cryopreservation of embryos using a centrifugation-based method for delipation without micromanipulation.
Production of polyclonal antibody to the bovine adrenal atrial natriuretic factor-R1 receptor.
Protease activity involvement in the passage of mammalian sperm through the zona pellucida.
Proteolysis of specific porcine zona pellucida glycoproteins by boar acrosin.
Relationship between two types of mouse sperm surface sites that mediate binding of sperm to the zona pellucida.
Relative efficacy of conventional sperm parameters and sperm penetration bioassay to assess bull fertility in vitro.
Serine proteases selectively control the output of 18-hydroxycorticosterone and aldosterone in stimulated zona glomerulosa tissue of the rat adrenal.
Solubilization of porcine zonae pellucidae by trypsin and pronase.
Spontaneous zona reaction in the mouse as a limiting factor for the time in which an oocyte may be fertilized.
Studies on zona hardening in rat oocytes that are matured in vitro in a serum-free medium.
The action of acrosin on the zona pellucida.
The effectiveness of trypsin treatment to remove Sendai virus adhering to the zona pellucida of mouse preimplantation embryos.
The zona-free hamster oocyte penetration test: a simple procedure using a DNA fluorescent stain to detect the male pronucleus formation.
Topographical characterization of the domain structure of the bovine adrenal atrial natriuretic factor R1 receptor.
Trypsin stimulation of aldosterone and 18-hydroxycorticosterone production by rat adrenal zona glomerulosa tissue is mediated by activation of protein kinase C.
Trypsin treatment of bovine embryos after in vitro exposure to infectious bovine rhinotracheitis virus or bovine herpesvirus-4.
Trypsin treatment of bovine ova after in vitro exposure to vesicular stomatitis virus.
Ultrastructure of opossum oocyte investing coats and their sensitivity to trypsin and hyaluronidase.
Vascular and adrenal reninlike activity in chronically diabetic rats.
[Effects of agents used for removal of zona pellucida on human sperm penetration into zona-free hamster egg]
[Obtaining zona-free ova from the golden hamster (Mesocricetus auratus Waterhouse)]
[The significance of acrosin and proteinase-inhibitors in human reproduction]
HIV Infections
Thrombin activates envelope glycoproteins of HIV type 1 and enhances fusion.
Hyaline Membrane Disease
Limited fat digestion in infants with bronchopulmonary dysplasia.
Trypsin in hyaline membrane disease.
TRYPSIN IN HYALINE MEMBRANE DISEASE.
[Trypsic inhibitors in serum and hyaline membrane disease (author's transl)]
Hydatidiform Mole
Flow cytometric DNA analyses of 105 fresh hydatidiform moles, with correlations to prognosis.
Hyperaldosteronism
[Comparative evaluation of the efficacy of methods of cryo- and trypsin activation of inactive renin in vitro]
Hyperalgesia
Antagonism of the proinflammatory and pronociceptive actions of canonical and biased agonists of protease-activated receptor-2.
Chronic compression or acute dissociation of dorsal root ganglion induces cAMP-dependent neuronal hyperexcitability through activation of PAR2.
Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome.
The C-terminus of murine S100A9 protein inhibits hyperalgesia induced by the agonist peptide of protease-activated receptor 2 (PAR2).
The proteinase inhibitor camostat mesilate suppresses pancreatic pain in rodents.
Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia.
Hypercalcemia
Mutations in the calcium-sensing receptor: A new genetic risk factor for chronic pancreatitis?
Hyperglycemia
Effect of acute hyperglycemia on basal and bombesin-stimulated pancreaticobiliary secretion in humans.
Effect of acute hyperglycemia on basal and cholecystokinin stimulated exocrine pancreatic secretion in humans.
Hyperglycemia reduces pancreaticobiliary secretion in response to modified sham feeding in humans.
Recombinant buckwheat trypsin inhibitor decreases fat accumulation via the IIS pathway in Caenorhabditis elegans.
The control of hyperglycemia by a novel trypsin resistant oral insulin preparation in alloxan induced type I diabetic mice.
The effect of acute hyperglycemia on meal-stimulated gastric, biliary, and pancreatic secretion, and serum gastrin.
Hyperinsulinism
Relationship between circulating levels of pancreatic proteolytic enzymes and pancreatic hormones.
Hyperlipidemias
Recombinant buckwheat trypsin inhibitor decreases fat accumulation via the IIS pathway in Caenorhabditis elegans.
Urinary Trypsin Inhibitor Reduced Inflammation Response Induced by Hyperlipidemia.
Hyperlipoproteinemia Type III
The beta very low density lipoprotein present in hepatic lipase deficiency competitively inhibits low density lipoprotein binding to fibroblasts and stimulates fibroblast acyl-CoA:cholesterol acyltransferase.
Hyperlipoproteinemia Type IV
Serum immunoreactive trypsin in type IV hyperlipoproteinemia.
Hyperlipoproteinemias
Serum immunoreactive trypsin in type IV hyperlipoproteinemia.
The beta very low density lipoprotein present in hepatic lipase deficiency competitively inhibits low density lipoprotein binding to fibroblasts and stimulates fibroblast acyl-CoA:cholesterol acyltransferase.
Hyperparathyroidism, Primary
Pancreatitis risk in primary hyperparathyroidism: relation to mutations in the SPINK1 trypsin inhibitor (N34S) and the cystic fibrosis gene.
Hypersensitivity
ALLERGY TO TRYPSIN.
Anaphylactic reactions to a cow's milk whey protein hydrolysate (Alfa-Ré, Nestlé) in infants with cow's milk allergy.
Cloning and expression of trypsin-encoding cDNA from Blattella germanica and its possibility as an allergen.
Epithelial expression and function of trypsin-3 in irritable bowel syndrome.
Hypersensitivity to purified trypsin and chymotrypsin.
Identification and partial purification of serologically defined Boophilus microplus larval antigens by natural ectoparasite exposure.
Ligand-induced changes in hepatitis C virus NS5B polymerase structure.
Partial proteolysis as a probe of the conformation of the gamma subunit in activated soluble and membrane-bound chloroplast coupling factor 1.
Serum trypsin inhibitory capacity and pi phenotypes. II. Prevalence of alpha1-antitrypsin deficiency in an allergy population.
Two Cardiac Arrests that Occurred after the Administration of Sugammadex: A Case of Kounis Syndrome.
[Anaphylactoid reaction to trypsin following local administration of Dontisolon ointment]
[Effect of trypsin on the development of a humoral immune response and of delayed hypersensitivity]
[Occupational Allergies to Trypsin and Chymotrypsin].
Hypersensitivity, Delayed
Immunogenicity of hapten-carrier conjugates associated with liposomes.
[Effect of trypsin on the development of a humoral immune response and of delayed hypersensitivity]
Hypersensitivity, Immediate
Hypersensitivity to pancreatic extracts in parents of patients with cystic fibrosis.
Immediate hypersensitivity to hog trypsin resulting from industrial exposure.
Hypertension
Activation and measurement of plasma prorenin in the rat.
Angiotensin-II administration is useful for the detection of liver metastasis from pancreatic cancer during pharmacoangiographic computed tomography.
Angiotensin-II and endothelin-1 levels in children with renoprival hypertension.
Direct comparison of inorganic nitrite and nitrate on vascular dysfunction and oxidative damage in experimental arterial hypertension.
RENAL INSUFFICIENCY FOLLOWING TRYPSIN INJECTION INTO THE RENAL ARTERIES.
The renin-angiotensin system, blood pressure, and heart structure in patients with hereditary vitamin D-resistance rickets (HVDRR).
[A case of local recurrence of rectal cancer successfully treated by UFT combined with two-route CDDP chemotherapy under the AT-II induced hypertension]
[An AT-II blocker in patients with type II diabetes and arterial hypertension]
[Effect of an angiotensin-converting-enzyme inhibitor on the plasma concentration of cytokines and vasoactive molecules in patients with coronary heart disease and hypertension].
[Effect of trypsin and heparin electrophoresis on the state of the kallikrein-kinin system in hypertension]
[Studies on pathological changes in cases of the aged retinal vessels, hypertension, and absolute glaucoma with the trypsin digestion method]
[The clinical and pharmacokinetic evaluation of two-route chemotherapy with cisplatin and sodium thiosulfate in combination with angiotensin II]
[The hypertensive effect induced with angiotensin II and the physiological and pharmacokinetic aspects of two-route chemotherapy using CDDP and STS]
[The influence of nasal continual positive airway pressure on some vasoactive substances in patients with obstructive sleep apnea syndrome]
[Tumor vascularity under hypertension induced by intravenous infusion of angiotensin II--angiographic and radionuclide angiographic observations]
[Two-route chemotherapy under AT-II induced hypertension using totally implanted injection port system in liver metastases derived from digestive cancers]
Hypertension, Malignant
Malignant hypertension: a syndrome associated with low plasma kininogen and kinin potentiating factor.
Plasma-levels of endothelin-1 and angiotensin-II and reactivity of arterial blood pressure to exogenous sympathomimetics and vasoactive peptides in rat model of malignant renal hypertension.
Hypertension, Portal
Role of angiotensin II in liver fibrosis-induced portal hypertension and therapeutic implications.
Hypertension, Pulmonary
Proteinase-activated receptor (PAR)-mediated vasorelaxation in pulmonary arteries from normotensive and hypoxic pulmonary hypertensive rats.
The ontogeny of human pulmonary angiotensin-converting enzyme and its aberrant expression may contribute to the pathobiology of bronchopulmonary dysplasia (BPD).
[Effect of captopril on hypoxia-induced pulmonary hypertension in pigs]
Hyperthyroidism
The effect of hyperthyroidism on gastric emptying rates and pancreatic exocrine and biliary secretion in man.
[Effects of experimental hyperthyroidism on the phospholipase A2, lipase, cholesterolesterase and trypsin activity of the pancreatic juice and of the pancreas in rats]
[PURPURA PROVOKED BY HYPERTHYROIDISM AND INFLUENCE ON THIS BY TRYPSIN AND A PROTEOLYTIC INHIBITOR.]
Hyphema
The role of trypsin in experimentally induced hyphema.
Trypsin in resorption of hyphemas.
Hypoglycemia
Culture of islets of Langerhans from an infant with intractable neonatal hypoglycemia: cytochemical and radioimmunological studies.
Reflex splanchnic nerve stimulation increases levels of proenkephalin A mRNA and proenkephalin A-related peptides in the rat adrenal medulla.
Hypoparathyroidism
Familial idiopathic hypoparathyroidism, sensorineural deafness and renal dysplasia.
Hypoproteinemia
Enterokinase and trypsin activities in pancreatic insufficiency and diseases of the small intestine.
Hypotension
A new experimental model for gallstone pancreatitis: short-termed pancreatico-biliary duct obstruction and exocrine stimulation with systemic hypotension in rats.
Enhanced tumor localization of monoclonal antibody by treatment with kininase II inhibitor and angiotensin II.
Evidence for the involvement of a plasma kallikrein-kinin system in the immediate hypotension produced by endotoxin in anaesthetized rats.
Further evidence of bradykinin involvement in septic shock: reduction of kinin production in vivo and improved survival in rats by use of polymer tailored SBTI with longer t1/2.
Human urinary trypsin inhibitor, urinastatin, prevents pancreatic injuries induced by pancreaticobiliary duct obstruction with cerulein stimulation and systemic hypotension in the rat.
Involvement of EDHF in the hypotension and increased gastric mucosal blood flow caused by PAR-2 activation in rats.
Kallikrein-kinin system in the plasma of the snake Bothrops jararaca.
Mesenteric Lymph Drainage Alleviates Acute Kidney Injury Induced by Hemorrhagic Shock without Resuscitation.
Protease-activated receptor-2 involvement in hypotension in normal and endotoxemic rats in vivo.
Urinary trypsin inhibitor reduces LPS-induced hypotension by suppressing tumor necrosis factor-alpha production through inhibition of Egr-1 expression.
[Pharmacological studies of FUT-175, nafamstat mesilate. II. Effects on experimental acute pancreatitis]
Hypothyroidism
Hypothyroidism with elevated pancreatic amylase and lipase without clinical symptoms: A case report.
Protease inhibitors in sera as possible indicators of familial hypothyroidism.
Idiopathic Pulmonary Fibrosis
Detection of antibodies in serum of patients with idiopathic pulmonary fibrosis against isolated rat alveolar type II cells.
Safety of postoperative administration of human urinary trypsin inhibitor in lung cancer patients with idiopathic pulmonary fibrosis.
Ileitis
Protease-activated receptor 2, dipeptidyl peptidase I, and proteases mediate Clostridium difficile toxin A enteritis.
Ileus
Pigbel in Papua New Guinea: an ancient disease rediscovered.
The pigbel story of Papua New Guinea.
Immunoglobulin G4-Related Disease
Serum trypsin and TCR as novel markers for predicting disease activity in IgG4-related disease.
Immunoglobulin Light-chain Amyloidosis
Optimal conditions and the advantages of using laser microdissection and liquid chromatography tandem mass spectrometry for diagnosing renal amyloidosis.
Incontinentia Pigmenti
Histopathologic and trypsin digestion studies of the retina in incontinentia pigmenti.
Infections
112 bluetongue virus infection in cattle after transfer of bovine in vivo-derived embryos.
A 65-kDa trypsin-sensible membrane cell protein as a possible receptor for dengue virus in cultured neuroblastoma cells.
A bacterially produced virus enhancing factor from an entomopoxvirus enhances nucleopolyhedrovirus infection in armyworm larvae.
A modified plaque assay method for accurate analysis of infectivity of influenza viruses with uncleaved hemagglutinin.
A Novel Helper Phage Enabling Construction of Genome-Scale ORF-Enriched Phage Display Libraries.
A novel method to rescue and culture duck Astrovirus type 1 in vitro.
A Novel Neuraminidase-Dependent Hemagglutinin Cleavage Mechanism Enables the Systemic Spread of an H7N6 Avian Influenza Virus.
A protein secreted in vivo by Echinococcus granulosus inhibits elastase activity and neutrophil chemotaxis.
Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites.
Active 1918 pandemic flu viral neuraminidase has distinct N-glycan profile and is resistant to trypsin digestion.
Amiodarone alters late endosomes and inhibits SARS coronavirus infection at a post-endosomal level.
Analysis of cell fusion induced by bovine coronavirus infection.
Antibody-dependent enhancement of influenza disease promoted by increase in hemagglutinin stem flexibility and virus fusion kinetics.
Application of an Inclined Settler for Cell Culture-Based Influenza A Virus Production in Perfusion Mode.
BMP9-induced osteogenetic differentiation and bone formation of muscle-derived stem cells.
Bovine herpesvirus-1 associated with single, trypsin-treated embryos was not infective for uterine tubal cells.
Buccal and intramuscular trypsin in respiratory tract infection.
CAP, a new human suspension cell line for influenza virus production.
Cell surface receptors for lactate dehydrogenase-elevating virus on subpopulation of macrophages.
Cellular changes in primary rabbit kidney cells resembling those caused by certain viruses.
Changes in the intestinal enzyme activity of lambs during chronic infection with Trichostrongylus vitrinus.
Characterization of a persistent respiratory syncytial virus showing a low-fusogenic activity associated to an impaired F protein.
Characterization of avian reovirus-induced cell fusion: the role of viral structural proteins.
Characterization of Clostridium perfringens TpeL toxin gene carriage, production, cytotoxic contributions, and trypsin sensitivity.
Characterization of Glycosylation Profiles of HIV-1 Transmitted/Founder Envelopes by Mass Spectrometry.
Characterization of SNP1, a cell wall-degrading trypsin, produced during infection by Stagonospora nodorum.
Characterization of the infectious salmon anemia virus fusion protein.
Characterization of the reproduction of influenza A epidemic viruses in cell cultures.
Clarithromycin suppresses induction of monocyte chemoattractant protein-1 and matrix metalloproteinase-9 and improves pathological changes in the lungs and heart of mice infected with influenza A virus.
Cleavage and serum reactivity of the severe acute respiratory syndrome coronavirus spike protein.
Cleavage of protein prM is necessary for infection of BHK-21 cells by tick-borne encephalitis virus.
Comparative analysis of expressed genes from cacao meristems infected by Moniliophthora perniciosa.
Comparative susceptibilities of insect cell lines to infection by the occlusion-body derived phenotype of baculoviruses.
Conditioned Medium from Enterohemorrhagic Escherichia coli-Infected T84 Cells Inhibits Signal Transducer and Activator of Transcription 1 Activation by Gamma Interferon.
Delay time for influenza virus hemagglutinin-induced membrane fusion depends on hemagglutinin surface density.
Deletion of the SNP1 trypsin protease from Stagonospora nodorum reveals another major protease expressed during infection.
Detection of bovine viral diarrhoea virus nucleic acid, but not infectious virus, in bovine serum used for human vaccine manufacture.
Development and viability of bovine preimplantation embryos after the in vitro infection with bovine herpesvirus-1 (BHV-1): immunocytochemical and ultrastructural studies.
Development of a rapid and sensitive quantitative assay for rotavirus based on flow cytometry.
Differential gene expression from midguts of refractory and susceptible lines of the mosquito, Aedes aegypti, infected with Dengue-2 virus.
Diisopropylamine dichloroacetate, a novel pyruvate dehydrogenase kinase 4 inhibitor, as a potential therapeutic agent for metabolic disorders and multiorgan failure in severe influenza.
Discordant varicella-zoster virus glycoprotein C expression and localization between cultured cells and human skin vesicles.
Ectopic trypsin in the myocardium promotes dilated cardiomyopathy after influenza A virus infection.
Effects of cell differentiation on replication of A/WS/33, WSN, and A/PR/8/34 influenza viruses in mouse brain cell cultures: biological and immunological characterization of products.
Effects of Clostridium perfringens beta-toxin on the rabbit small intestine and colon.
Effects of herpes simplex virus strains on human fibroblast and lymphocyte chromosomes and the localization of chromosomal aberrations.
Effects of inhibitors of Toll-like receptors, protease-activated receptor-2 signalings and trypsin on influenza A virus replication and upregulation of cellular factors in cardiomyocytes.
Efficient formation of vesicular stomatitis virus pseudotypes bearing the native forms of hepatitis C virus envelope proteins detected after sonication.
Efficient influenza A virus production in high cell density using the novel porcine suspension cell line PBG.PK2.1.
Emergence of a potentially pathogenic H5N2 influenza virus in chickens.
Energy metabolic disorder is a major risk factor in severe influenza virus infection: Proposals for new therapeutic options based on animal model experiments.
Enhanced production of infectious rotavirus in BSC-1 cell cultures by various factors in the presence of absence of trypsin.
Enhancement of antigen incorporation and infectivity of cell cultures by human rotavirus.
Enhancement of fluorescent antibody staining of viral antigens in formalin-fixed tissues by trypsin digestion.
Enhancement of plaque formation and cell fusion of an enteropathogenic coronavirus by trypsin treatment.
Enzymuria in antibiotic therapy of acute infections.
Experimental trypsin-induced urothelial cell separation in vivo.
Expression and sorting of rat plasma kallikrein in POMC-producing AtT-20 cells.
Expression of gangliosides as receptors at the cell surface controls infection of NCTC 2071 cells by Sendai virus.
Expression of HLA class I heavy chains and beta 2-microglobulin does not affect human cytomegalovirus infectivity.
Formation of bacteriophage MS2 infectious units in a cell-free translation system.
Freezing or adding trypsin inhibitor to equine intestinal contents extends the lifespan of Clostridium perfringens beta toxin for diagnostic purposes.
Genomes and transcriptomes of partners in plant-fungal-interactions between canola (Brassica napus) and two Leptosphaeria species.
High Serum Trypsin Levels and the -409 T/T Genotype of PRSS1 Gene Are Susceptible to Neonatal Sepsis.
Host envelope glycoprotein processing proteases are indispensable for entry into human cells by seasonal and highly pathogenic avian influenza viruses.
HVJ infection in alveolar macrophages of various laboratory animals.
Identification and characterization of taglin, a mannose 6-phosphate binding, trypsin-activated lectin from Giardia lamblia.
IL-1? is a key cytokine that induces trypsin upregulation in the influenza virus-cytokine-trypsin cycle.
Immunodepletion of albumin for two-dimensional gel detection of new mouse acute-phase protein and other plasma proteins.
Impairment of multicycle influenza virus growth in Vero (WHO) cells by loss of trypsin activity.
In situ cleavage of the baculovirus occlusion derived virus receptor binding protein P74 in the peroral infectivity complex.
In vitro silencing of a serine protease inhibitor suppresses Trichinella spiralis invasion, development, and fecundity.
In vivo and in vitro propagation and transmission of Toggenburg orbivirus.
In Vivo Efficacy of Anuran Trypsin Inhibitory Peptides against Staphylococcal Skin Infection and the Impact of Peptide Cyclization.
Induction of a phosphomannosyl binding lectin activity in Giardia.
Infection of cultured human intestinal cells by monkey RRV and human Wa rotavirus as a function of intestinal epithelial cell differentiation.
Infection of resistant avian cells by subgroup B Rous sarcoma virus.
Infectious mechanisms of enteropathogenic bovine coronaviruses.
Influence of Leishmania infection on blood-meal digestion in the sandflies Phlebotomus papatasi and P. langeroni.
Influenza virus-cytokine-protease cycle in the pathogenesis of vascular hyperpermeability in severe influenza.
Inhibition of Glossina morsitans midgut trypsin activity by D-glucosamine.
Inhibition of trypsin expression in Lutzomyia longipalpis using RNAi enhances the survival of Leishmania.
Intact intestinal mRNAs and intestinal epithelial cell esterase, but not Cryptosporidium parvum, reach mesenteric lymph nodes of infected mice.
Interaction of bovine viral diarrhea virus with bovine cumulus-oocyte complex during IVM: Detection in permissive cells.
Interactions of Francisella tularensis with Alveolar Type II Epithelial Cells and the Murine Respiratory Epithelium.
Intra-amniotic administration of exogenous pulmonary surfactant for improving in lung maturity of fetal rabbits with intrauterine infection caused by premature rupture of membranes.
Isolation and characterization of phagosomes containing Chlamydia psittaci from L cells.
Isolation and purification of amastigotes of Trypanosoma cruzi from cultured vero cells.
Lectin/glycan interactions play a role in recognition in a coral/dinoflagellate symbiosis.
Lepeophtheirus salmonis secretory/excretory products and their effects on Atlantic salmon immune gene regulation.
Lipid composition and amino acid uptake during rotavirus infection and protection with trypsin inhibitor in malnourished infant mice.
Low sweat electrolytes in a patient with cystic fibrosis.
Mass spectrometric analysis of host cell proteins interacting with dengue virus nonstructural protein 1 in dengue virus-infected HepG2 cells.
Molecular immune response of the American lobster (Homarus americanus) to the White Spot Syndrome Virus.
Monitoring activation of the antiviral pattern recognition receptors RIG-I and PKR by limited protease digestion and native PAGE.
Monoclonal immunoglobulin A antibody to the major outer membrane protein of the Chlamydia trachomatis mouse pneumonitis biovar protects mice against a chlamydial genital challenge.
Multiplication and haemadsorbing activity of infectious salmon anaemia virus in the established Atlantic salmon cell line.
Neonatal infection does not affect the immunoreactive trypsinogen screening test for cystic fibrosis.
Neonatal rotavirus infections.
Neonatal screening for cystic fibrosis.
New insights into rotavirus entry machinery: stabilization of rotavirus spike conformation is independent of trypsin cleavage.
Newcastle Disease Virus Induced Pathologies Severely Affect the Exocrine and Endocrine Functions of the Pancreas in Chickens.
Novel Potential Biomarkers for Opisthorchis viverrini Infection and Associated Cholangiocarcinoma.
Pathophysiology and diagnostic value of urinary trypsin inhibitors.
Peanut Seed Cultivars with Contrasting Resistance to Aspergillus parasiticus Colonization Display Differential Temporal Response of Protease Inhibitors.
Physiological and immunological characterization of Caribbean spiny lobsters Panulirus argus naturally infected with Panulirus argus Virus 1 (PaV1).
Polypeptide composition of rotavirus empty capsids and their possible use as a subunit vaccine.
Potential use of Atlantic cod trypsin in biomedicine.
Protease-stable polycationic photosensitizer conjugates between polyethyleneimine and chlorin(e6) for broad-spectrum antimicrobial photoinactivation.
Protection against rotavirus challenge in mice orally inoculated with trypsin inhibitor.
Protective efficacy of trypsin inhibitor on the the gut following rotavirus infection in malnourished infant mice.
Proteolytic processing of the astrovirus capsid.
Quantifying the effect of trypsin and elastase on in vitro SARS-CoV infections.
Quantitative-PCR assessment of Cryptosporidium parvum cell culture infection.
Randomized trial of the efficacy of intravaginal ulinastatin administration for the prevention of preterm birth in women with a singleton pregnancy and both cervical shortening and inflammation of lower genital tract.
Rapid focus reduction neutralization test of influenza A and B viruses in microtiter system.
Receptor-bound porcine epidemic diarrhea virus spike protein cleaved by trypsin induces membrane fusion.
Reliable titration of filamentous bacteriophages independent of pIII fusion moiety and genome size by using trypsin to restore wild-type pIII phenotype.
Replication of influenza A and B viruses in human diploid cells.
Resistance of Phlebotomus papatasi to infection with Leishmania donovani is modulated by components of the infective bloodmeal.
Role of alpha 2-macroglobulin in phagocytosis of group A and C streptococci.
Role of host trypsin-type serine proteases and influenza virus-cytokine-trypsin cycle in influenza viral pathogenesis. Pathogenesis-based therapeutic options.
Role of inhibitors of serine peptidases in protecting Leishmania donovani against the hydrolytic peptidases of sand fly midgut.
Role of the pneumococcal autolysin (murein hydrolase) in the release of progeny bacteriophage and in the bacteriophage-induced lysis of the host cells.
Role of trypsin in the replication of Avian metapneumovirus subtype C (strain MN-2a) and its entry into the Vero cells.
Role of VP3 in human rotavirus internalization after target cell attachment via VP7.
Rosellinia necatrix infection induces differential gene expression between tolerant and susceptible avocado rootstocks.
Rotavirus-specific protein synthesis is not necessary for recognition of infected cells by virus-specific cytotoxic T lymphocytes.
Sarcocystis neurona infection in gamma interferon gene knockout (KO) mice: Comparative infectivity of sporocysts in two strains of KO mice, effect of trypsin digestion on merozoite viability, and infectivity of bradyzoites to KO mice and cell culture.
SARS-CoV-2 Production in a Scalable High Cell Density Bioreactor.
Selection of rotavirus VP4 cell receptor binding domains for MA104 cells using a phage display library.
Sendai virus infection up-regulates trypsin I and matrix metalloproteinase-9, triggering viral multiplication and matrix degradation in rat lungs and lung L2 cells.
Soybean trypsin inhibitor confers protection against rotavirus infection in infant mice.
Specific macrophage immunity to Sendai virus: macrophage aggregation in vitro with Sendai virus by cytophilic antibodies.
Statistical optimization of influenza H1N1 production from batch cultures of suspension Vero cells (sVero).
Structure-based phylogeny identifies avoralstat as a TMPRSS2 inhibitor that prevents SARS-CoV-2 infection in mice.
Study of the chemical nature of Frp/3 cell recognition units for hepatitis A virus.
Stunting syndrome in broilers: effect of age and exogenous amylase and protease on performance, development of the digestive tract, digestive enzyme activity, and apparent digestibility.
Suitability of MDCK cells grown in a serum-free medium for influenza virus production.
Susceptibility of rodent cell lines to rat coronaviruses and differential enhancement by trypsin or DEAE-dextran.
Susceptibility of staphylococcal biofilms to enzymatic treatments depends on their chemical composition.
Syncytiotrophoblast is a barrier to maternal-fetal transmission of herpes simplex virus.
Targeting host cell proteases to prevent SARS-CoV-2 invasion.
Temporal association of the herpes simplex virus genome with histone proteins during a lytic infection.
Temporal synthesis of proteins and RNAs during human astrovirus infection of cultured cells.
The clinical effect of proteolytic enzyme containing bromelain and trypsin on urinary tract infection evaluated by double blind method.
The effect of proteolytic enzymes and protease inhibitors on the interaction Trypanosoma cruzi-fibroblasts.
The effect of surface membrane modifications of fibroblastic cells on the entry process of Trypanosoma cruzi trypomastigotes.
The effects of midgut serine proteases on dengue virus type 2 infectivity of Aedes aegypti.
THE ELABORATION OF SPECIFIC SOLUBLE SUBSTANCE BY PNEUMOCOCCUS DURING GROWTH.
The old but new: Can unfractioned heparin and low molecular weight heparins inhibit proteolytic activation and cellular internalization of SARS-CoV2 by inhibition of host cell proteases?
The role of the peritrophic matrix and red blood cell concentration in Plasmodium vivax infection of Anopheles aquasalis.
The role of trypsin in plaque formation by simian rotavirus SA-11.
The trypsin-enhanced infection of porcine epidemic diarrhea virus is determined by the S2 subunit of the spike glycoprotein.
The uristatin dipstick is useful in distinguishing upper respiratory from urinary tract infections.
The use of trypsin in urinary tract infections.
Therapeutic effects of continuous intraarterial antibiotic infusion in preventing pancreatic infection in experimental acute necrotizing pancreatitis.
Timecourse microarray analyses reveal global changes in gene expression of susceptible Glycine max (soybean) roots during infection by Heterodera glycines (soybean cyst nematode).
Topography of the Human Papillomavirus Minor Capsid Protein L2 during Vesicular Trafficking of Infectious Entry.
Transformation of mouse peritoneal macrophages and bone marrow cells by simian virus 40.
Transmembrane serine protease TMPRSS2 activates hepatitis C virus infection.
Treatment of pyogenic infections and wounds with buccal trypsin.
Trypanosoma cruzi-fibroblastic cell interactions necessary for cellular invasion.
Trypanosoma cruzi: inhibition of host cell uptake of infective bloodstream forms by alpha-2-macroglobulin.
Trypsin and chymotrypsin-like enzymes of the sandfly Phlebotomus papatasi infected with Leishmania and their possible role in vector competence.
Trypsin cleavage of the baculovirus occlusion-derived virus attachment protein P74 is prerequisite in per os infection.
Trypsin enhancement of rotavirus infectivity: mechanism of enhancement.
Trypsin of Litopenaeus vannamei is required for the generation of hemocyanin-derived peptides.
Trypsin promotes efficient influenza vaccine production in MDCK cells by interfering with the antiviral host response.
Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection.
Urinary trypsin inhibitor treatment ameliorates acute lung and liver injury resulting from sepsis in a rat model.
Urinary trypsin inhibitory activity for the diagnosis of bacterial infection: a prospective study in 690 patients.
Urinary trypsin levels observed in pancreas transplant patients with duodenocystostomies promote in vitro fibrinolysis and in vivo bacterial adherence to urothelial surfaces.
Vaccinia virus tropism for primary hematolymphoid cells is determined by restricted expression of a unique virus receptor.
Wave microcarrier cultivation of MDCK cells for influenza virus production in serum containing and serum-free media.
Wolbachia infection in Aedes aegypti mosquitoes alters blood meal excretion and delays oviposition without affecting trypsin activity.
Xylanase supplementation of a wheat-based diet improved nutrient digestion and mRNA expression of intestinal nutrient transporters in broiler chickens infected with Clostridium perfringens.
[Analysis of SNPs and enzymatic disorder in the patients of influenza-associated encephalopathy: disorder of fatty acid metabolism in mitochondria induced by high fever]
[Clinical evaluation of the effect of a combination of tetracycline-L-methylenbysine with trypsin and alpha-chymotrypsin on acute and chronic oral infections]
[Clinical value of the determination of urinary antitrypsin activity]
[Comparative study of avian influenza virus propagation in the cell culture and chick embryos]
[Development of a live culture of cold-adapted reassortant influenza vaccines]
[Effect of proteolytic enzymes on kanamycin pharmacokinetics in experimental suppurative infection]
[Effects of intramuscular trypsin on the course of experimental infection by vaccinia virus in rabbits.]
[Experience in treating a herpetic infection with trypsin]
[Immunofluorescence reaction for rotavirus analysis in fecal specimens]
[Isolation of canine rotavirus and study of its immunobiological properties]
[ON LOCAL APPLICATION OF TRYPSIN IN THE TREATMENT OF BONE INFECTIONS.]
[Study of incorporation of highly-cleaved H7 hemagglutinin, expressed by a recombinant vector in virions of superinfecting influenza viruses]
[The effect of oral rehydration therapy on pancreatic function in patients with acute intestinal infections]
[The influence of an infective dose and the duration of infection with Ascaridia galli on trypsin and alpha-amylase activity in the pancreas of chickens fed with diets of different protein levels]
[The treatment of urinary tract infection following transurethral prostatic resection by use of trypure solution.]
[Trypsin and alpha-amylase activities in the pancreas of guinea pigs. II. Effect of per os and intra-intestinal infection with invasive ova of Ascaris suum]
[Trypsin and alpha-amylase activity in the pancreas of guinea pigs. I. The influence of infective dose and duration of infection by Ascaris suum Goeze, 1782]
[Trypsin and alpha-amylase activity in the pancreas of guinea pigs. V. Effects of administration of vitamin A and B 2 during the larval stage of ascariasis]
[Urinary trypsin inhibitor as an acute phase reactant]
[Value of the assay of protein SAA and urinary antitrypsin activity in osteoarticular infections]
Infectious Bovine Rhinotracheitis
Evaluation of the effects of different trypsin treatments on semen quality after BHV-1 inactivation, and a comparison of the results before and after freezing, assessed by a computer image analyzer.
Trypsin treatment of bovine embryos after in vitro exposure to infectious bovine rhinotracheitis virus or bovine herpesvirus-4.
Infectious Mononucleosis
Impaired cellular immunecompetence in infectious mononucleosis as assessed by a local graft-versus-host reaction in rats and restoration of the immunecompetence by trypsin.
Infertility, Male
Tumor-associated trypsin inhibitor as a possible marker in male infertility.
Inflammatory Bowel Diseases
Antibodies to a trypsin sensitive pancreatic antigen in chronic inflammatory bowel disease: specific markers for a subgroup of patients with Crohn's disease.
Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2.
Influence of inflammatory bowel disease on the distribution and concentration of pancreatic secretory trypsin inhibitor within the colon.
Trypsin-sensitive modulation of intestinal epithelial MD-2 as mechanism of lipopolysaccharide tolerance.
Influenza in Birds
A novel chicken lung epithelial cell line: characterization and response to low pathogenicity avian influenza virus.
A viable recombinant rhabdovirus lacking its glycoprotein gene and expressing influenza virus hemagglutinin and neuraminidase is a potent influenza vaccine.
Biological and genetic characterization of a low-pathogenicity avian influenza H6N2 virus originating from a healthy Eurasian coot.
Establishment of MDCK Stable Cell Lines Expressing TMPRSS2 and MSPL and Their Applications in Propagating Influenza Vaccine Viruses in Absence of Exogenous Trypsin.
Evaluation of human intestinal epithelial differentiated cells (Caco-2) for replication, plaque formation and isolation of avian influenza viruses.
Glycosylation at hemagglutinin Asn-167 protects the H6N1 avian influenza virus from tryptic cleavage at Arg-201 and maintains the viral infectivity.
MDCK cells that express proteases TMPRSS2 and HAT provide a cell system to propagate influenza viruses in the absence of trypsin and to study cleavage of HA and its inhibition.
Mutations at the cleavage site of the hemagglutinin after the pathogenicity of influenza virus A/chick/Penn/83 (H5N2).
Plaque morphology of Italian H7N1 LPAI isolates in MDCK cells and in primary cells of different avian species.
Protease activation mutants elicit protective immunity against highly pathogenic avian influenza viruses of subtype H7 in chickens and mice.
Influenza, Human
A simplified plaque assay for influenza viruses in Madin-Darby kidney (MDCK) cells.
A viable recombinant rhabdovirus lacking its glycoprotein gene and expressing influenza virus hemagglutinin and neuraminidase is a potent influenza vaccine.
Accumulation of mini-plasmin in the cerebral capillaries causes vascular invasion of the murine brain by a pneumotropic influenza A virus: implications for influenza-associated encephalopathy.
Action of rimantadine on the structure of influenza A virus haemagglutinin.
Activation of influenza A viruses by trypsin treatment.
Active 1918 pandemic flu viral neuraminidase has distinct N-glycan profile and is resistant to trypsin digestion.
Alterations in antioxidant defences in lung and liver of mice infected with influenza A virus.
An assay for the receptor-destroying activity of influenza C virus.
An efficient method for introducing defined lipids into the plasma membrane of mammalian cells.
Animal viruses are able to fuse with prokaryotic cells. Fusion between Sendai or influenza virions and Mycoplasma.
Antigenic properties of a transport-competent influenza HA/HIV Env chimeric protein.
CAP, a new human suspension cell line for influenza virus production.
Cell surface expression of biologically active influenza C virus HEF glycoprotein expressed from cDNA.
Characterization of Site-Specific glycosylation in Influenza A Virus Hemagglutinin produced by Spodoptera frugiperda insect cell line.
Characterization of the reconstructed 1918 Spanish influenza pandemic virus.
Co-infection between influenza virus and flagellated bacteria.
Complementation between avirulent Newcastle disease virus and a fusion protein gene expressed from a retrovirus vector: requirements for membrane fusion.
Conformationally selective biophysical assay for influenza vaccine potency determination.
Construction and characterization of an infectious vaccinia virus recombinant that expresses the influenza hemagglutinin gene and induces resistance to influenza virus infection in hamsters.
Correction to: IL-1b is a key cytokine that induces trypsin upregulation in the influenza virus-cytokine-trypsin cycle.
Delay time for influenza virus hemagglutinin-induced membrane fusion depends on hemagglutinin surface density.
Detection of influenza A and B neutralizing antibodies in vaccinated ferrets and macaques using specific biotin-streptavidin conjugated antibodies.
Differences in trypsin susceptibility among influenza viruses and relationship of the susceptibility to the antigenic type or subtype of the virus.
Differentiated swine airway epithelial cell cultures for the investigation of influenza A virus infection and replication.
Ectopic trypsin in the myocardium promotes dilated cardiomyopathy after influenza A virus infection.
Effect of trypsin on a susceptible strain of influenza A virus.
Effects of inhibitors of Toll-like receptors, protease-activated receptor-2 signalings and trypsin on influenza A virus replication and upregulation of cellular factors in cardiomyocytes.
Efficient influenza A virus production in high cell density using the novel porcine suspension cell line PBG.PK2.1.
Electron microscopy of influenza virus growth in a human lymphoblastic leukemia cell line, MOLT4 cells.
Endogenous protease-dependent replication of human influenza viruses in two MDCK cell lines.
Energy metabolic disorder is a major risk factor in severe influenza virus infection: Proposals for new therapeutic options based on animal model experiments.
Established cell line sensitive to influenza C virus.
Establishment of a genetically engineered chicken DF-1 cell line for efficient amplification of influenza viruses in the absence of trypsin.
Establishment of MDCK Stable Cell Lines Expressing TMPRSS2 and MSPL and Their Applications in Propagating Influenza Vaccine Viruses in Absence of Exogenous Trypsin.
Evaluation of human intestinal epithelial differentiated cells (Caco-2) for replication, plaque formation and isolation of avian influenza viruses.
Factors responsible for plaque formation of A/duck/Siberia/272/1998 (H13N6) influenza virus on MDCK cells.
Fusion characteristics of influenza C viruses.
Genetic Recombination for Antigenic Markers of Antigenically Different Strains of Influenza B Virus.
Growth activation of influenza virus by trypsin and effect of T-705 (favipiravir) on trypsin-optimized growth condition.
Growth characteristics of influenza virus type C in avian hosts. Brief report.
Heterogeneity of the MDCK Cell Line and Its Applicability for Influenza Virus Research.
High permissivity of human HepG2 hepatoma cells for influenza viruses.
Identification of trypsin I as a candidate for influenza A virus and Sendai virus envelope glycoprotein processing protease in rat brain.
IL-1? is a key cytokine that induces trypsin upregulation in the influenza virus-cytokine-trypsin cycle.
Immunobiological properties of influenza A (H7N9) hemagglutinin and neuraminidase proteins.
Immunofluorescent staining of influenza virus antigen in fixed and paraffin-embedded tissue of experimentally infected hamsters.
Impact of cultivation conditions on N-glycosylation of influenza virus a hemagglutinin produced in MDCK cell culture.
Impairment of multicycle influenza virus growth in Vero (WHO) cells by loss of trypsin activity.
In ovo and in vitro susceptibility of American alligators (Alligator mississippiensis) to avian influenza virus infection.
Inactivation of hemagglutinating capacity of type A influenza virus by trypsin treatment.
Inactivation of influenza B virus by normal guinea-pig serum.
Infection enhancement of influenza A NWS virus in primary murine macrophages by anti-hemagglutinin monoclonal antibody.
Influenza Hemagglutinin and M2 ion channel priming by trypsin: Killing two birds with one stone.
Influenza virus-cytokine-protease cycle in the pathogenesis of vascular hyperpermeability in severe influenza.
Influenza's Newest Trick.
Inhibition of influenza virus A/WSN replication by a trypsin inhibitor, 6-amidino-2-naphthyl p-guanidinobenzoate.
Insertion of a multibasic cleavage motif into the hemagglutinin of a low-pathogenic avian influenza H6N1 virus induces a highly pathogenic phenotype.
Interaction of influenza virus hemagglutinin with target membrane lipids is a key step in virus-induced hemolysis and fusion at pH 5.2.
Interferon in nasal secretions from infants with viral respiratory tract infections.
Isolation of influenza virus from muscle in myoglobinuric polymyositis.
MDCK cell cultures supplemented with high concentrations of trypsin exhibit remarkable susceptibility to influenza C virus.
MDCK cells that express proteases TMPRSS2 and HAT provide a cell system to propagate influenza viruses in the absence of trypsin and to study cleavage of HA and its inhibition.
Modifications to the hemagglutinin cleavage site control the virulence of a neurotropic H1N1 influenza virus.
Molecular analyses of the hemagglutinin genes of H5 influenza viruses: origin of a virulent turkey strain.
Mutation in the hemagglutinin of A/N-WS/33 influenza virus recombinants influencing sensitivity to trypsin and antigenic reactivity.
Necrotic Response to Low Pathogenic H9N2 Influenza Virus in Chicken Hepatoma Cells.
Optimization of trypsins for influenza A/H1N1 virus replication in MDCK SI-6 cells, a novel MDCK cell line.
Partial change of the ts-phenotype of cold-adapted influenza virus strain grown in canine kidney cells in the presence of trypsin.
Pathogenic significance of alpha-N-acetylgalactosaminidase activity found in the hemagglutinin of influenza virus.
Plaque assay and primary isolation of influenza A viruses in an established line of canine kidney cells (MDCK) in the presence of trypsin.
Plaque formation by influenza viruses in the presence of trypsin.
Potential use of Atlantic cod trypsin in biomedicine.
Production of influenza virus in serum-free mammalian cell cultures.
Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium.
Proteolytic enzymes in embryonated chicken eggs sustain the replication of egg-grown low-pathogenicity avian influenza viruses in cells in the absence of exogenous proteases.
Purification and cDNA cloning of a novel protease inhibitor secreted into culture supernatant by MDCK cells.
Replication of influenza A and B viruses in human diploid cells.
Replication of influenza A viruses in a green monkey kidney continuous cell line (Vero).
Rescue of a synthetic chloramphenicol acetyltransferase RNA into influenza virus-like particles obtained from recombinant plasmids.
Role of viral glycoproteins in haemolysis by influenza B virus.
Sequence and crystallization of influenza virus B/Beijing/1/87 neuraminidase.
SEROLOGIC AND ANTIGENIC PROPERTIES OF TYPE A INFLUENZA VIRUS AFTER TRYPSIN TREATMENT.
SPINT2 inhibits proteases involved in activation of both influenza viruses and metapneumoviruses.
Stability of infectious influenza A viruses to treatment at low pH and heating.
Structural variation occurring in the hemagglutinin of influenza virus A/turkey/Oregon/71 during adaptation to different cell types.
Suitability of MDCK cells grown in a serum-free medium for influenza virus production.
Susceptibility of continuous lines of monkey kidney cells to influenza and parainfluenza viruses in the presence of trypsin.
T cell recognition of the posttranslationally cleaved intersubunit region of influenza virus hemagglutinin.
Temperature sensitivity on growth and/or replication of H1N1, H1N2 and H3N2 influenza A viruses isolated from pigs and birds in mammalian cells.
The action of trypsin on normal serum inhibitors of influenza virus agglutination.
The action of vibrio and influenza virus enzymes and of periodate and trypsin on human red cells.
The cleavage of spike protein ??0???1/HA2 by trypsin permits activation of the M2 channel without its proteolytic cleavage in the influenza A virus.
THE EFFECT OF TRYPSIN ON INFLUENZA VIRUS.
The multiplication of an influenza C virus in an established line of canine kidney (MDCK) cells.
The use of components of plant origin in the development of production technology for live cold-adapted cultural influenza vaccine.
Thermolysin activation mutants with changes in the fusogenic region of an influenza virus hemagglutinin.
TMPRSS2 and TMPRSS4 facilitate trypsin-independent spread of influenza virus in Caco-2 cells.
Transmembrane phospholipid motions induced by F glycoprotein in hemagglutinating virus of Japan.
Trypsin increases pseudorabies virus production through activation of the ERK signalling pathway.
Trypsin promotes efficient influenza vaccine production in MDCK cells by interfering with the antiviral host response.
Trypsin-resistant protease activation mutants of an influenza virus.
Ts mutations in the genome of cold-adapted variants of human influenza virus A/Krasnodar/101/59 (H2N2) at different passage levels and their reproduction in lungs of hamsters.
Ultrastructure and some biological properties of influenza A virus. IV. Effect of proteolytic enzymes on viral particle.
[Analysis of SNPs and enzymatic disorder in the patients of influenza-associated encephalopathy: disorder of fatty acid metabolism in mitochondria induced by high fever]
[Characteristics of virion formation during mixed infection with influenza viruses A and B]
[Comparative tests for destruction of specific inhibitors of hemagglutination due to influenza virus by treatment of sera with filtrate from cultures of Vibrio cholerae, potassium periodate and trypsin.]
[Pathogenic effect of pandemic influenza virus H1N1 under replication in cultures of human cells].
[Study of incorporation of highly-cleaved H7 hemagglutinin, expressed by a recombinant vector in virions of superinfecting influenza viruses]
[The effect of trypsin on influenza A2 virus]
[The properties of the epidemic influenza viruses A and B strains circulating in Russia in the 2004-2005 epidemic season]
[The trypsin cleavage of hemagglutinin enhances the infectivity of the influenza virus in mice]
[Use of Caco-2 cells for isolation of influenza virus]
[Use of plant-origin components in roller cultivation of vaccine reassortant influenza virus strain H5N2].
Insulin Resistance
beta-Hydroxybutyrate increases the insulin sensitivity of adipocyte glucose transport at a postreceptor level.
Contraction-induced increase in muscle insulin sensitivity: requirement for a serum factor.
Impact of Renin-Angiotensin System in Hepatocellular Carcinoma.
Insulin resistance by uncleaved insulin proreceptor. Emergence of binding site by trypsin.
Losartan counteracts the hyper-reactivity to angiotensin II and ROCK1 over-activation in aortas isolated from streptozotocin-injected diabetic rats.
Mechanisms of insulin resistance in cultured fibroblasts from a patient with leprechaunism: resistance to proteolytic activation of glycogen synthase by trypsin.
Sesquiterpenes from Baizhu Stimulate Glucose Uptake by Activating AMPK and PI3K.
Insulinoma
Autoantibodies to IA-2 in IDDM: location of major antigenic determinants.
Detection of pancreatic islet 64,000 M(r) autoantigens in insulin-dependent diabetes distinct from glutamate decarboxylase.
Identification of protein tyrosine phosphatase-like IA2 (islet cell antigen 512) as the insulin-dependent diabetes-related 37/40K autoantigen and a target of islet-cell antibodies.
The 37/40-kilodalton autoantigen in insulin-dependent diabetes mellitus is the putative tyrosine phosphatase IA-2.
Intellectual Disability
Brief clinical report: interstitial deletion of the long arm of chromosome 10: del(10)(q11.2q21).
Expression and Characterization of Human Fragile X Mental Retardation Protein Isoforms and Interacting Proteins in Human Cells.
The Prader-Willi syndrome with a 15/3 translocation.
Intervertebral Disc Degeneration
Development of an intact intervertebral disc organ culture system in which degeneration can be induced as a prelude to studying repair potential.
Human and bovine spinal disc mechanics subsequent to trypsin injection.
Rheological and Dynamic Integrity of Simulated Degenerated Disc and Consequences after Cross-linker Augmentation.
Intestinal Obstruction
Pancreatic injury in equine acute abdomen evaluated by plasma trypsin activity and histopathology of pancreatic tissue.
Plasma trypsin level in horses suffering from acute intestinal obstruction.
Trypsin activity in stool and duodenal aspirate of neonates for differential diagnosis of intestinal obstruction.
Intestinal Volvulus
Pigbel in Papua New Guinea: an ancient disease rediscovered.
The pigbel story of Papua New Guinea.
Invasive Pulmonary Aspergillosis
Successful treatment of invasive pulmonary aspergillosis by transbronchial injection of urinary trypsin inhibitor and amphotericin B.
Iron Overload
Serum immunoreactive trypsin in beta-thalassaemia major.
Irritable Bowel Syndrome
Epithelial expression and function of trypsin-3 in irritable bowel syndrome.
Ischemic Attack, Transient
Ulinastatin alleviates neurological deficiencies evoked by transient cerebral ischemia via improving autophagy, Nrf-2-ARE and apoptosis signals in hippocampus.
Ischemic Stroke
Time course of inflammatory cytokines in acute ischemic stroke patients and their relation to inter-alfa trypsin inhibitor heavy chain 4 and outcome.
Keratitis
[On the therapy of herpes simplex keratitis with heparin and trypsin]
Keratitis, Herpetic
[On the therapy of herpes simplex keratitis with heparin and trypsin]
Keratoconus
Collagenolytic proteinases in keratoconus.
Keratosis, Seborrheic
Topical protease therapy as a novel method of epidermal ablation: preliminary report.
Kidney Calculi
Effects of ethylenediaminetetraacetic acid-4 sodium solution on the surface of renal calculi and the uroepithelium.
Kidney Diseases
[Comparison of the trypsin inhibitor activity in urine of donors and patients with kidney diseases]
Kidney Failure, Chronic
Angiotensin-II and endothelin-1 levels in children with renoprival hypertension.
Early-Onset Acute Recurrent and Chronic Pancreatitis Is Associated with PRSS1 or CTRC Gene Mutations.
Immunoreactive trypsin and pancreatic isoamylase activity in serum of patients with chronic renal failure or hepatic cirrhosis.
Pancreatic exocrine function in severe human chronic renal failure.
Plasma levels of pancreatic secretory trypsin inhibitor in relation to amylase and lipase in patients with acute and chronic renal failure.
Plasma pancreatic trypsinogens in chronic renal failure and after nephrectomy.
Plasma-immunoreactive trypsin in chronic renal failure.
Serum immunoreactive trypsin concentration after a Lundh meal. Its value in the diagnosis of pancreatic disease.
Serum trypsin in chronic renal failure and transplant patients.
Serum trypsin levels in acute pancreatic and non-pancreatic abdominal conditions.
The relative values of serum immuno-reactive trypsin concentration and total amylase activity in the diagnosis of mumps, chronic renal failure, and pancreatic disease.
Trypsin-like immunoreactivity in the diagnosis of acute pancreatitis.
[Clinical value of the determination of urinary antitrypsin activity]
[Evaluation of measuring serum trypsin by radioimmunoassay and clinical application for the study on the exocrine function in diabetics (author's transl)]
[Serum and urinary pancreatic secretory trypsin inhibitor concentration in patients with chronic renal failure]
Kidney Neoplasms
Tumor-associated trypsin inhibitor.
Kounis Syndrome
Two Cardiac Arrests that Occurred after the Administration of Sugammadex: A Case of Kounis Syndrome.
Kwashiorkor
Exocrine pancreatic function of children from the Ivory Coast compared to French children. Effect of kwashiorkor.
lactase deficiency
Effect of pancreatic proteases on intestinal lactase activity.
Laryngitis
[Treatment of subglottic laryngitis in children; importance of local treatment with trypsin.]
Leg Ulcer
Biochemical and biological profile of a new enzyme preparation from Antarctic krill (E. superba) suitable for debridement of ulcerative lesions.
Cleansing properties of stabilized trypsin and streptokinase-streptodornase in necrotic leg ulcers.
Degradation and liquefaction effect of streptokinase-Streptodornase and stabilized trypsin on necroses, crusts of fibrinoid, purulent exudate and clotted blood from leg ulcers.
Stability of the Cathelicidin Peptide LL-37 in a Non-healing Wound Environment.
[Molecular Characterization of Lucimycin Gene of Lucilia sericata].
[Pain reaction in patients with venous leg ulcers during treatment with Trypure]
Leishmaniasis
Leishmania donovani donovani antigens recognized by kala-azar patient sera and identification of cross-reacting antigens to Chagas' disease.
The effect of avian blood on Leishmania development in Phlebotomus duboscqi.
Leishmaniasis, Visceral
A ?-mercaptoethanol-modified enzyme-linked immunosorbent assay for diagnosis of canine visceral leishmaniasis.
Evaluation of cleaving agents other than trypsin in direct agglutination test for further improving diagnosis of visceral leishmaniasis.
Leprosy
The bacteriologic diagnosis of early leprosy by the trypsin digestion method.
Leprosy, Lepromatous
Oxidation of 3,4-dihydroxyphenylalanine by connective tissue constituents. Identification of Mycobacterium leprae not related to phenolase activity.
Lethargy
Treatment of a citrin-deficient patient at the early stage of adult-onset type II citrullinaemia with arginine and sodium pyruvate.
Leukemia
A trypsin inhibitor isolated from lymphatic leukemia cells.
Bromelain proteinases modulate the cd44 expression on human molt-4/8 leukemia and sk-mel-28 melanoma-cells in-vitro.
Extracellular protease trypsin activates amiloride-insensitive sodium channels in human leukemia cells.
Growth inhibition and induction of apoptosis in NB4 promyelocytic leukemia cells by trypsin inhibitor from sweet potato storage roots.
Heterogeneity of cell surface structures involved in cytotoxicity mediated by lymphokine activated killer cells.
Human T-cell leukemia-associated cell surface glycoprotein GP37: studies with three monoclonal antibodies and a rabbit antiserum.
In this issue: Proteomics 1/2009.
Isolation and Characterization of a Phaseolus vulgaris Trypsin Inhibitor with Antiproliferative Activity on Leukemia and Lymphoma Cells.
Isolation of an immunogenic polypeptide after limited trypsin hydrolysis of murine leukemia virus group-specific antigen.
Isolation of glycopeptides containing individual glycosylation sites of Friend murine leukemia virus glycoprotein: studies of glycosylation by methylation analysis.
Patterns of immunoglobulin staining in paraffin-embedded malignant lymphomas.
Preserving catalytic activity and enhancing biochemical stability of the therapeutic enzyme asparaginase by biocompatible multilayered polyelectrolyte microcapsules.
Proteolysis of soluble IgE-receptor complexes: localization of sites on IgE which interact with the Fc receptor.
Suppression of ADAM17-mediated Lyn/Akt pathways induces apoptosis of human leukemia U937 cells: Bungarus multicinctus protease inhibitor-like protein-1 uncovers the cytotoxic mechanism.
Surface aminopeptidase activity of rat natural killer cells. I. Biochemical and biological properties.
The disulfide bond arrangement of leukemia inhibitory factor: homology to oncostatin M and structural implications.
The role of cell membrane-associated urinary trypsin inhibitor in tumor cell invasion and metastasis.
Trypsin isoinhibitors with antiproliferative activity toward leukemia cells from Phaseolus vulgaris cv "White Cloud Bean".
Urinary trypsin-inhibitor protects neutrophil chemotaxis in the inflammatory response.
Use of trypsin for rapid and efficient purification of murine sarcoma and leukemia virus.
[Identification of ectomesenchymal stem cells of human fetal facial processes and spontaneous differentiation to smooth muscle cells]
[Preparation of immobilized trypsin micro monolithic column and its application to rapid digestion of trace proteins].
[Proteolytic activity and content of trypsin inhibitor in the blood serum of patients with leukemia]
Leukemia L1210
Chalone-like inhibition of Ehrlich ascites cell proliferation in vitro by an ultrafiltrate obtained from the ascitic fluid.
Isolation and characterization of a novel trypsin inhibitor from fresh lily bulbs.
Serine proteinase inhibitor from lymphocytic leukemia cells. Properties and copurification with DNA.
Trypsin isoinhibitors with antiproliferative activity toward leukemia cells from Phaseolus vulgaris cv "White Cloud Bean".
Leukemia, Erythroblastic, Acute
Tumor-associated trypsin participates in cancer cell-mediated degradation of extracellular matrix.
Leukemia, Hairy Cell
Patterns of immunoglobulin staining in paraffin-embedded malignant lymphomas.
Leukemia, Large Granular Lymphocytic
Identification and partial characterization of a novel plasma membrane-associated lytic factor isolated from highly purified adherent lymphokine-activated killer cells.
Leukemia, Lymphocytic, Chronic, B-Cell
Patterns of immunoglobulin staining in paraffin-embedded malignant lymphomas.
Sodium periodate stimulation of normal and chronic lymphocytic leukemia lymphocytes. II. The use of neuraminidase and trypsin to probe the nature of the response.
Leukemia, Lymphoid
Chalone-like inhibition of Ehrlich ascites cell proliferation in vitro by an ultrafiltrate obtained from the ascitic fluid.
Confirmation by peptide sequence and co-expression on various cell types of the identity of CD44 and P85 glycoprotein.
Serine proteinase inhibitor from lymphocytic leukemia cells. Properties and copurification with DNA.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
A homogeneous cellular histone deacetylase assay suitable for compound profiling and robotic screening.
Identification of variant translocations in chronic myeloid leukemia by fluorescence in situ hybridization.
Induction of apoptosis by buckwheat trypsin inhibitor in chronic myeloid leukemia K562 cells.
Leukemia, Myeloid, Acute
Cell surface glycosaminoglycans in normal and leukemic leukocytes.
Combination assay of urinary free L-fucose and trypsin inhibitor may be useful indicators of disease activity in patients with hematologic malignancies.
[Apoptosis of HL-60 cells induced by recombinant common Buckwheat trypsin inhibitor]
Leukemia, Promyelocytic, Acute
[Preparation of immobilized trypsin micro monolithic column and its application to rapid digestion of trace proteins].
Leukocytosis
Use of fibrinolytic agents in the prevention of postoperative adhesion formation.
Leukopenia
Efficacy of two-route chemotherapy using cis-diamminedichloroplatinum(II) and its antidote, sodium thiosulfate, in combination with angiotensin II in a rat limb tumor.
Leukocytes are required for the trypsin-induced increase in lung vascular permeability.
Lewy Body Disease
Altered Expression of Brain Proteinase-Activated Receptor-2, Trypsin-2 and Serpin Proteinase Inhibitors in Parkinson's Disease.
Lipodystrophy
Use of trypsin in prevention and restoration of insulin lipodystrophy.
Liver Cirrhosis
Angiotensin II protects primary rat hepatocytes against bile salt-induced apoptosis.
Angiotensin-I-converting enzyme inhibitors may be an alternative anti-angiogenic strategy in the treatment of liver fibrosis and hepatocellular carcinoma. Possible role of vascular endothelial growth factor.
Angiotensin-II and vascular endothelial growth factor interaction plays an important role in rat liver fibrosis development.
Angiotensin-II type 1 receptor interaction is a major regulator for liver fibrosis development in rats.
Anti-fibrogenic effects of captopril and candesartan cilexetil on the hepatic fibrosis development in rat. The effect of AT1-R blocker on the hepatic fibrosis.
Blockade of renin-angiotensin system in antifibrotic therapy.
Cross talk between toll-like receptor-4 signaling and angiotensin-II in liver fibrosis development in the rat model of non-alcoholic steatohepatitis.
Effects of six months losartan administration on liver fibrosis in chronic hepatitis C patients: a pilot study.
Immunoreactive trypsin and pancreatic isoamylase activity in serum of patients with chronic renal failure or hepatic cirrhosis.
pH and concentration of pancreatic enzymes in aspirates from the human duodenum during digestion of a standard meal in patients with biliary or hepatic disorders.
Preventive effect of urinary trypsin inhibitor on the development of liver fibrosis in mice.
Serum trypsin inhibitory activity and alpha-1-antitrypsin level in liver diseases.
Serum trypsin inhibitory capacity and alpha 1-antitrypsin levels in liver cirrhosis and hepatoma.
[Activity of serum trypsin in patients with chronic hepatitis and liver cirrhosis as an index of extrasecretory function of the pancreas]
[Postoperative change of serum protease inhibitor and C-reactive protein level--with special reference to surgical resection of liver cirrhosis]
Liver Cirrhosis, Alcoholic
Pancreatic secretion after secretin and cholecystokinin stimulation in chronic alcoholics with and without cirrhosis.
Liver Cirrhosis, Biliary
Measurement of trypsin in duodenal juice by radioimmunoassay.
Mitochondrial antibodies in primary biliary cirrhosis. VI. Association of the complement fixing antigen with a component of the mitochondrial F1-ATPase complex.
Pancreatic involvement in patients with Sjögren's syndrome and primary biliary cirrhosis.
Serum immunoreactive trypsin and pancreatic lipase in primary biliary cirrhosis.
The pancreas in primary biliary cirrhosis and primary sclerosing cholangitis.
Liver Diseases
Dietary wheat amylase trypsin inhibitors promote features of murine non-alcoholic fatty liver disease.
Liver disease in alpha-1-antitrypsin deficiency: prognostic indicators.
Plasma and urine levels of urinary trypsin inhibitor in patients with chronic liver diseases and hepatocellular carcinoma.
Serine peptidase inhibitor Kazal type III (SPINK3) promotes BRL-3A cell proliferation by targeting the PI3K-AKT signaling pathway.
Serum trypsin inhibitory activity and alpha-1-antitrypsin level in liver diseases.
Transport of proteases across neonatal intestine and development of liver disease in infants with alpha-1 antitrypsin deficiency.
[Evaluation of measuring serum trypsin by radioimmunoassay and clinical application for the study on the exocrine function in diabetics (author's transl)]
[Two forms of alkaline phosphatase in blood serum in liver diseases]
Liver Neoplasms
Anti-tumoral effects of a trypsin inhibitor derived from buckwheat in vitro and in vivo.
Isolation of Fibroblast-Activation Protein-Specific Cancer-Associated Fibroblasts.
Time-resolved immunofluorometric assay of trypsin-1 complexed with alpha(1)-antitrypsin in serum: increased immunoreactivity in patients with biliary tract cancer.
Tumor-associated trypsin inhibitor in pancreatic diseases.
Ulinastatin reduces the resistance of liver cancer cells to epirubicin by inhibiting autophagy.
Lung Diseases
A community study of the relation of alpha1-antitrypsin levels to obstructive lung diseases.
Association of trypsin-2 with activation of gelatinase B and collagenase-2 in human bronchoalveolar lavage fluid in vivo.
Comparison of three methods for the determination of serum alpha-1-antitrypsin in patients with pulmonary diseases.
High expression of pulmonary proteinase-activated receptor 2 in acute and chronic lung injury in preterm infants.
Inhibition of neutrophil elastase-induced interleukin-8 gene expression by urinary trypsin inhibitor in human bronchial epithelial cells.
INTRAMUSCULAR use of crystalline trypsin in pulmonary diseases.
Low sweat electrolytes in a patient with cystic fibrosis.
The ontogeny of human pulmonary angiotensin-converting enzyme and its aberrant expression may contribute to the pathobiology of bronchopulmonary dysplasia (BPD).
Trypsin binding activity of alpha 2-macroglobulin in cystic fibrosis and other lung diseases.
Versican-A Critical Extracellular Matrix Regulator of Immunity and Inflammation.
[Protease activity and the level of antibodies to connective tissue elements in various lung diseases]
[Proteolytic activity and trypsin inhibitor content in the blood serum in nonspecific lung diseases]
[Trypsin aerosol therapy of chronic pulmonary diseases.]
[Trypsin therapy in pulmonary diseases, 1955-1960.]
Lung Diseases, Interstitial
Bolus infusion of human urinary trypsin inhibitor improves intractable interstitial pneumonia in patients with connective tissue diseases.
Human urinary trypsin inhibitor bolus infusion improved severe interstitial pneumonia in mixed connective tissue disease.
Lung Diseases, Obstructive
Obstructive lung disease and trypsin inhibitors in alpha-1-antitrypsin deficiency.
Serum trypsin inhibitory capacity and Pi phenotypes. I. Methods and control values.
[Capacity of the serum trypsin inhibitor in chronic obstructive lung diseases]
Lung Injury
2',4',6'-Tris(methoxymethoxy) chalcone (TMMC) attenuates the severity of cerulein-induced acute pancreatitis and associated lung injury.
Antioxidative role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide.
Effects of pulmonary artery perfusion with urinary trypsin inhibitor as a lung protective strategy under hypothermic low-flow cardiopulmonary bypass in an infant piglet model.
Effects of ulinastatin treatment on the cardiopulmonary bypass-induced hemodynamic instability and pulmonary dysfunction.
Effects of urinary protease inhibitor on inflammatory response during on-pump coronary revascularisation. Effect of ulinastatin on inflammatory response.
Hemin-activated macrophages home to the pancreas and protect from acute pancreatitis via heme oxygenase-1 induction.
Loss of Shp2 in alveoli epithelia induces deregulated surfactant homeostasis, resulting in spontaneous pulmonary fibrosis.
New properties of the soybean trypsin inhibitor: Inhibition of human neutrophil elastase and its effect on acute pulmonary injury.
Pancreatitis severity in mice with impaired CFTR function but pancreatic sufficiency is mediated via ductal and inflammatory cells-Not acinar cells.
Protective Effect of Urinary Trypsin Inhibitor on the Development of Radiation-Induced Lung Fibrosis in Mice.
Protective Effects of Lithospermum erythrorhizon Against Cerulein-Induced Acute Pancreatitis.
Pulmonary trypsin-2 in the development of bronchopulmonary dysplasia in preterm infants.
Selective inhibition of BET proteins reduces pancreatic damage and systemic inflammation in bile acid- and fatty acid ethyl ester- but not caerulein-induced acute pancreatitis.
Suppression of superantigen-induced lung injury and vasculitis by preadministration of human urinary trypsin inhibitor.
Trypsin and activation of circulating trypsinogen contribute to pancreatitis-associated lung injury.
Up-regulation of trypsin and mesenchymal MMP-8 during development of hyperoxic lung injury in the rat.
[Biological effect of (60)Cogamma ray on alveolar type II cells and interstitial cells of alveoliar septum in radiation pulmonary injury.]
Lung Neoplasms
Cbl-b accelerates trypsin-induced cell detachment through ubiquitination and degradation of proline-rich tyrosine kinase 2.
Coal dust alters beta-naphthoflavone-induced aryl hydrocarbon receptor nuclear translocation in alveolar type II cells.
Identification of a rare p.G320R alpha-1-antitrypsin variant in emphysema and lung cancer patients.
Isolation of small cell lung cancer-associated antigen from human brain.
Isolation of urinary trypsin inhibitor-like inhibitor from human lung cancer tissue.
Jizanpeptins, Cyanobacterial Protease Inhibitors from a Symploca sp. Cyanobacterium Collected in the Red Sea.
Monoclonal antibody that distinguishes small-cell lung cancer from non-small-cell lung cancer.
P-selectin mediates adhesion of platelets to neuroblastoma and small cell lung cancer.
Protease-activated receptor 2 induces migration and promotes Slug-mediated epithelial-mesenchymal transition in lung adenocarcinoma cells.
Safety of postoperative administration of human urinary trypsin inhibitor in lung cancer patients with idiopathic pulmonary fibrosis.
Serum alpha1-antitrypsin in patients with lung cancer or abnormal sputum cytology.
Serum levels of alpha1-antitrypsin and alpha2-macroglobulin in lung cancer.
Serum tumor markers CEA, CA 50, TATI, and NSE in lung cancer screening.
Trypsinization severely perturbs radioiodide transport via membrane Na/I symporter proteolysis: implications for reporter gene imaging.
Tumor-associated trypsin inhibitor (TATI) in the diagnosis of lung cancer.
[Advances of human epididymis protein 4 in lung cancer].
Lupus Nephritis
Immunohistochemical detection of immunoglobulins and complements in formaldehyde-fixed and paraffin-embedded renal biopsy tissues; an adjunct for diagnosis of glomerulonephritis.
Lymphatic Metastasis
Association of trypsin expression with recurrence and poor prognosis in human esophageal squamous cell carcinoma.
Lymphoma
A novel trypsin inhibitor from Peltophorum dubium seeds, with lectin-like properties, triggers rat lymphoma cell apoptosis.
A Storage Protein-Like Trypsin Inhibitor from the Moth Bean (Phaseolus acutifolius) with Antiproliferative Activity Toward Lymphoma Cells.
A thymus cell marker in murine leukemia virus-induced lymphomas of rats.
Application of flow cytometry to studies on the distribution, persistence, and regeneration rate of Epstein-Barr virus receptors.
Characterization of K+ currents in rat malignant lymphocytes (Nb2 cells).
Effects of horse and fetal calf serum on the expression of tumor-associated antigen and tumorigenicity of L5178Y leukemia/lymphoma cells.
Increase in Gross (G) antigen sites on the surface of AKR virus-induced rat lymphoma cells after treatment with trypsin.
Inhibition of [3H]TdR and [3H]CdR incorporation in an established human lymphoma cell line by trypsin treatment.
Isolation and Characterization of a Phaseolus vulgaris Trypsin Inhibitor with Antiproliferative Activity on Leukemia and Lymphoma Cells.
Neuraminidase "unmasking" and failure of trypsin to "unmask" -D-galactose-like sites on erythrocyte, lymphoma, and normal and virus-transformed fibroblast cell membranes.
Patterns of immunoglobulin staining in paraffin-embedded malignant lymphomas.
Peltophorum dubium and soybean Kunitz-type trypsin inhibitors induce human Jurkat cell apoptosis.
Silver enhancement of polymerised diaminobenzidine: increased sensitivity for immunoperoxidase staining.
The effects of monensin on blood-borne arrest and glycosylation of BL/VL3 lymphoma cells.
Lymphoma, B-Cell
Evidence for a functional receptor for cyclosporin A on the surface of lymphocytes.
Immunoglobulin light chain staining in paraffin-embedded tissue using a heat mediated epitope retrieval method.
Stable oligosaccharide microheterogeneity at individual glycosylation sites of a murine major histocompatibility antigen derived from a B-cell lymphoma.
Lymphoma, Follicular
Patterns of immunoglobulin staining in paraffin-embedded malignant lymphomas.
Lymphoma, Non-Hodgkin
Combination assay of urinary free L-fucose and trypsin inhibitor may be useful indicators of disease activity in patients with hematologic malignancies.
Onco-embryonic antigens on murine normal adult cells.
Lymphopenia
Do lymphocytes play a pro-inflammatory role in any pharmacological type of rat paw edema?
Macular Edema
Retinal trypsin digest study of cystoid macular edema associated with peripheral choroidal melanoma.
Malabsorption Syndromes
Comparison of ochratoxin, aflatoxin, and T-2 toxin for their effects on selected parameters related to digestion and evidence for specific metabolism of carotenoids in chickens.
Elevated levels of serum pancreatic secretory trypsin inhibitor (PSTI) in patients with malabsorption syndrome.
Malaria
Analysis of Erythrocyte Invasion Mechanisms of Plasmodium falciparum Clinical Isolates Across 3 Malaria-Endemic Areas in Ghana.
Antibodies from malaria-exposed pregnant women recognize trypsin resistant epitopes on the surface of Plasmodium falciparum-infected erythrocytes selected for adhesion to chondroitin sulphate A.
Antibody-mediated inhibition of Aedes aegypti midgut trypsins blocks sporogonic development of Plasmodium gallinaceum.
Different effects of modulation of mosquito (Diptera:Culicidae) trypsin activity on the infectivity of two human malaria (Hemosporidia:Plasmodidae) parasites.
Erythrocyte invasion and merozoite ligand gene expression in severe and mild Plasmodium falciparum malaria.
Members of a trypsin gene family in Anopheles gambiae are induced in the gut by blood meal.
Plasmodium falciparum: VAR2CSA expressed during pregnancy-associated malaria is partially resistant to proteolytic cleavage by trypsin.
Malnutrition
A follow-up study of annular pancreas in infants and children.
An integrated liquid crystal sensing device assisted by the surfactant-embedded smart hydrogel.
Comparative changes between pancreas and pancreatic juice digestive enzyme contents during nutritional rehabilitation following severe protein malnutrition in the rat.
Elevated serum immunoreactive pancreatic cationic trypsinogen in acute malnutrition: evidence of pancreatic damage.
PEGylated polymeric nanocapsules for oral delivery of trypsin targeted to the small intestines.
Serum trypsin as measure of pancreatic exocrine function in children with protein calorie malnutrition.
The interrelationship of enterokinase and trypsin activities in intractable diarrhea of infancy, celiac disease, and intravenous alimentation.
Marek Disease
In vitro cytotoxicity against Marek's disease lymphoblastoid cell lines after enzymatic removal of Marek's disease tumor-associated surface antigen.
Marek's Disease Herpesviruses I. Production and Preliminary Characterization of Marek's Disease Herpesvirus A Antigen.
Massive Hepatic Necrosis
Plasma and urine levels of urinary trypsin inhibitor in patients with acute and fulminant hepatitis.
Transmembrane serine protease TMPRSS2 activates hepatitis C virus infection.
Mastitis
Characterization of hemolytic activity of Staphylococcus aureus strains isolated from bovine mastitic milk.
Effect of frequent milkings on milk NAGase, plasmin, trypsin inhibitory capacity and the quality of whey as the growth medium for mastitis pathogens.
Factors affecting the distribution of lipoprotein lipase activity between serum and casein micelles in bovine milk.
Immuno-Detection of C3a, a C3 Complement Activated Product in Mastitis Milk, a Potential Diagnostic Marker.
Status of mastitis as an emerging disease in improved and periurban dairy farms in India.
Mastocytoma
Characterisation of tryptase and a granzyme H-like chymase isolated from equine mastocytoma tissue.
Maxillary Sinusitis
[Experiences with trypsin therapy of chronic maxillary sinusitis.]
[USE OF TRYPSIN IN THE TREATMENT OF MAXILLARY SINUSITIS PATIENTS.]
Measles
Affinity for measles virus anti-haemolysin of a residual immunoglobulin M in sera of some patients with multiple sclerosis.
Detection of bovine viral diarrhoea virus nucleic acid, but not infectious virus, in bovine serum used for human vaccine manufacture.
Enhancement of fluorescent antibody staining of viral antigens in formalin-fixed tissues by trypsin digestion.
Immunological relationships between homologous structural polypeptides of measles and canine distemper virus.
Isolation and comparative study of the nucleocapsids of measles and canine distemper viruses from infected cells.
Polar appearance and nonligand induced spreading of measles virus hemagglutinin at the surface of chronically infected cells.
The effect of trypsin on measles virus antigenicity.
[The mechanisms of persistent measles virus infection in HEp-2 cells]
Meconium Ileus
Immaturity of the myenteric plexus is the aetiology of meconium ileus without mucoviscidosis: a histopathologic study.
Immunoreactive trypsin levels in neonates with meconium ileus.
Neonatal screening for cystic fibrosis in Wales and the West Midlands: 1. Evaluation of immunoreactive trypsin test.
Medulloblastoma
[Isolation and characterization of brain tumor stem cells in human medulloblastoma.]
Melanoma
A human melanoma cell line highly susceptible to influenza C virus.
Action of trypsin and detergents on tyrosinase of normal and malignant melanocytes.
Application of an improved density gradient electrophoresis apparatus to the separation of proteins, cells and subcellular organelles.
Bioactive Composition, Antioxidant Activity, and Anticancer Potential of Freeze-Dried Extracts from Defatted Gac (Momordica cochinchinensis Spreng) Seeds.
Cell surface proteolysis by serine proteinases enhances RGD-sensitive melanoma cell adhesion on fibrinogen and vitronectin.
Comparison of the antigenicity of melanotic and amelanotic melanoma cells after the release of surface glycoproteins by trypsin.
Comparison of the surface glycoprotein components in the isolated cells of hamster melanotic and amelanotic melanomas.
Cystine-knot peptides targeting cancer-relevant human cytotoxic T lymphocyte-associated antigen 4 (CTLA-4).
Cytoadherence characteristics of Plasmodium falciparum isolates from Thailand: evidence for chondroitin sulfate a as a cytoadherence receptor.
Enzymatic susceptibility and spontaneous release of human melanoma tumor-associated antigens.
Heterogeneity of cell surface structures involved in cytotoxicity mediated by lymphokine activated killer cells.
Immunoaffinity purification of melanoma growth stimulatory activity.
Immunochemical characterization of a tumor-associated antigen defined by a monoclonal antibody.
Inability of murine melanoma melanosomal "tyrosinase" (L-dopa oxidase) to oxidize tyrosine to melanin in polyacrylamide gel systems.
Influence of cell detachment on the respiration rate of tumor and endothelial cells.
Inhibition of human natural cytotoxicity by macromolecular antiproteases.
Inhibition of STAT3 signalling contributes to the antimelanoma action of atractylenolide II.
MDCK cell cultures supplemented with high concentrations of trypsin exhibit remarkable susceptibility to influenza C virus.
Mixture of trypsin, chymotrypsin and papain reduces formation of metastases and extends survival time of C57Bl6 mice with syngeneic melanoma B16.
Novel downstream molecular targets of SIRT1 in melanoma: a quantitative proteomics approach.
Partial characterisation of human melanoma cell-derived factors that stimulate fibroblast glycosaminoglycan synthesis.
Particulate tyrosinase of human malignant melanoma. Solubilization, purification following trypsin treatment, and characterization.
Polyenzyme preparation Wobe-Mugos inhibits growth of solid tumors and development of experimental metastases in mice.
Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis.
Proteolysis with trypsin of mammalian tyrosinase isoforms from B16 mouse melanoma.
Rapid dissociation of adherent human tumor cells by ultrasound.
Retinal trypsin digest study of cystoid macular edema associated with peripheral choroidal melanoma.
Serine proteinase inhibitors produced by human melanoma cell lines.
Stimulation of human metastatic melanoma colony-forming cells by an acid-sensitive factor in human platelet sonicate.
Tissue-cultured head and neck tumors: their use in in vitro assays of immune response.
Transient expression of high molecular weight, heat sensitive, trypsin-resistant form of tyrosinase in B-16 melanoma cells.
Melanoma, Amelanotic
Comparison of the antigenicity of melanotic and amelanotic melanoma cells after the release of surface glycoproteins by trypsin.
Heterogeneity of the surface material in isolated cells of transplantable hamster melanomas.
Melanoma, Experimental
Actin in B16 melanoma cells of differing metastatic potential. Effects of trypsin and serum.
Atractylenolide II induces G1 cell-cycle arrest and apoptosis in B16 melanoma cells.
Distinct and non-cross-reactive epitopes are recognized on B16 melanoma by LAK cells and anti-B16 monoclonal antibodies.
Mixture of trypsin, chymotrypsin and papain reduces formation of metastases and extends survival time of C57Bl6 mice with syngeneic melanoma B16.
Memory Disorders
Substrate-dependent competency of the catalytic triad of prolyl oligopeptidase.
Meningioma
High resolution genomic profiling and classical cytogenetics in a group of benign and atypical meningiomas.
Metabolic syndrome in relation to risk of meningioma.
Presence of the proteinase-activated receptor-2 (PAR-2) in human brain tumor cells--trypsin- and SLIGRL-induced calcium response in primary cultured meningiomas.
Meningococcal Infections
Meningococcal infection and proteolytic control.
Menorrhagia
Hemorrhage induced by intrauterine devices: control by local proteinase inhibition.
Mesothelioma
Human mesothelioma cells produce factors that stimulate the production of hyaluronan by mesothelial cells and fibroblasts.
Hyaluronan receptors are expressed on human malignant mesothelioma cells but not on normal mesothelial cells.
Mesothelioma, Malignant
Urinary trypsin inhibitor suppresses migration of malignant mesothelioma.
Metabolic Diseases
Recombinant buckwheat trypsin inhibitor decreases fat accumulation via the IIS pathway in Caenorhabditis elegans.
Metabolic Syndrome
A Trypsin Inhibitor from Tamarind Reduces Food Intake and Improves Inflammatory Status in Rats with Metabolic Syndrome Regardless of Weight Loss.
Citrin deficiency as a cause of chronic liver disorder mimicking non-alcoholic fatty liver disease.
Discovery of a novel series of guanidinebenzoates as gut-restricted enteropeptidase and trypsin dual inhibitors for the treatment of metabolic syndrome.
Trypsin inhibitors: promising candidate satietogenic proteins as complementary treatment for obesity and metabolic disorders?
Metrorrhagia
Hemorrhage induced by intrauterine devices: control by local proteinase inhibition.
Nano-LC based proteomic approach identifies that E6AP interacts with ENO1 and targets it for degradation in breast cancer cells.
[Sample pre-processing for mass spectrometric analysis of glycoprotein structure]
Microaneurysm
A quantitative and cartographic study of retinal microvasculopathy in acquired immunodeficiency syndrome.
Clinicopathologic correlations in diabetic retinopathy. I. Histology and fluorescein angiography of microaneurysms.
Histological and ultrastructural investigation of retinal microaneurysm development in diabetic patients.
Histopathology of argon laser photocoagulation in juvenile diabetic retinopathy.
The development of retinopathy in sucrose-fed and streptozotocin-diabetic rats.
[A morphological study of the retinal vessels in experimental diabetic rats]
Milk Hypersensitivity
Lymphocyte Responses to Chymotrypsin- or Trypsin V-Digested beta-Lactoglobulin in Patients with Cow's Milk Allergy.
T-cell epitope-containing hypoallergenic ?-lactoglobulin for oral immunotherapy in milk allergy.
Mitochondrial Encephalomyopathies
Application of molecular imaging combined with genetic screening in diagnosing MELAS, diabetes and recurrent pancreatitis.
Mixed Connective Tissue Disease
Human urinary trypsin inhibitor bolus infusion improved severe interstitial pneumonia in mixed connective tissue disease.
Mouth Diseases
Antibody response against foot and mouth disease virus (FMDV). Part I: Responses measured in sera of vaccinated steers with complete virus, trypsin treated virus, 12 S virus subunits and heterologous virus.
Antibody response against foot and mouth disease virus (FMDV). Part II: Responses measured in fractionated sera of infected steers with complete virus, trypsin treated virus, 12 S virus subunits, VIA and heterologous virus.
[The stabilizing and reactivating influence of trypsin on the virus of Teschen disease (swine paralysis) and inactivation of foot and mouth disease virus by this enzyme.]
Mucocutaneous Lymph Node Syndrome
Ulinastatin, a urinary trypsin inhibitor, for the initial treatment of patients with Kawasaki disease: a retrospective study.
[Clinical utility of ulinastatin, urinary protease inhibitor in acute Kawasaki disease]
Multiple Myeloma
Amidase activity of human Bence Jones proteins.
Combination assay of urinary free L-fucose and trypsin inhibitor may be useful indicators of disease activity in patients with hematologic malignancies.
Comparative study of workflows optimized for in-gel, in-solution, and on-filter proteolysis in the analysis of plasma membrane proteins.
Enzyme-induced modification of the surface properties of lymphoid cells in malignant disease. I. Effect of trypsin on rosette formation by lymphocytes in myelomatosis.
Expression of a buckwheat trypsin inhibitor gene in Escherichia coli and its effect on multiple myeloma IM-9 cell proliferation.
Multiple Sclerosis
A randomized, double-blind, placebo-controlled study of oral hydrolytic enzymes in relapsing multiple sclerosis.
Anoxia leads to a rapid translocation of human trypsinogen 4 to the plasma membrane of cultured astrocytes.
Development of robust targeted proteomics assays for cerebrospinal fluid biomarkers in multiple sclerosis.
Myelin basic protein, an autoantigen in multiple sclerosis, is selectively processed by human trypsin 4.
Prevention of murine EAE by oral hydrolytic enzyme treatment.
Urinary trypsin inhibitor levels are reduced in cerebrospinal fluid of multiple sclerosis and neuromyelitis optica patients during relapse.
Mumps
Detection of bovine viral diarrhoea virus nucleic acid, but not infectious virus, in bovine serum used for human vaccine manufacture.
Sequence determination of the mumps virus HN gene.
The relative values of serum immuno-reactive trypsin concentration and total amylase activity in the diagnosis of mumps, chronic renal failure, and pancreatic disease.
[Favorable effect of trypsin on the receptivity of formalinized erythrocytes of the rat and mouse to mumps virus.]
[Various mechanisms of the pathogenesis and etiotropic therapy of neurologic forms of epidemic parotitis]
Muscle Spasticity
Different reactivity of the proximal and distal segments of the radial artery to vasoconstrictors in patients undergoing coronary artery bypass grafting.
Microcirculation of the normal and inflamed canine pancreas.
Muscular Dystrophy, Duchenne
Increased rate of cell-substratum detachment of fibroblasts from patients with Duchenne muscular dystrophy.
[Screening for hereditary diseases. What other screening?]
Myasthenia Gravis
[Myasthenia gravis probably caused by benzidamine hydrochloride, bromelains and trypsin]
Mycoses
A maize trypsin inhibitor (ZmTIp) with limited activity against Aspergillus flavus.
Myocardial Infarction
Intravenous trypsin in experimental myocardial infarction.
Pathophysiology and diagnostic value of urinary trypsin inhibitors.
Myocardial Ischemia
Neuroprotective Effect of Ulinastatin on Spinal Cord Ischemia-Reperfusion Injury in Rabbits.
[Effect of trypsin-like enzyme inhibitor on certain metabolic processes in the acute period of experimental myocardial ischemia]
[Study on the relation between hypertensive left ventricular hypertrophy in very old people with neurohormonal factors and ventricular arrhythmias]
Myocarditis
Ectopic trypsin in the myocardium promotes dilated cardiomyopathy after influenza A virus infection.
Up-regulation of ectopic trypsins in the myocardium by influenza A virus infection triggers acute myocarditis.
Myoma
Non-phosphorylative transglucosylation and other biochemical indices in serum and uterine myoma in women.
[Establishment of primary culture of cells derived from uterine leiomyoma]
Myxoma
MALDI-TOF mass spectroscopy detects the capsid structural instabilities created by deleting the myxoma virus cupro-zinc SOD1 homolog M131R.
Nasopharyngeal Carcinoma
Two legume defense proteins suppress the mobility of nasopharyngeal carcinoma cells.
Neonatal Sepsis
High Serum Trypsin Levels and the -409 T/T Genotype of PRSS1 Gene Are Susceptible to Neonatal Sepsis.
Neoplasm Metastasis
A bifunctional hybrid molecule of the amino-terminal fragment of urokinase and domain II of bikunin efficiently inhibits tumor cell invasion and metastasis.
A novel discriminant score based on tumor-associated trypsin inhibitor for accurate diagnosis of metastasis in patients with breast cancer.
Acinar-islet cell carcinoma presenting as insulinoma.
Activation of type IV procollagenases by human tumor-associated trypsin-2.
Anti-metastatic therapy by urinary trypsin inhibitor in combination with an anti-cancer agent.
Antiproliferative activity of Lavatera cashmeriana- protease inhibitors towards human cancer cells.
Association of trypsin expression with recurrence and poor prognosis in human esophageal squamous cell carcinoma.
Association of trypsin expression with tumour progression and matrilysin expression in human colorectal cancer.
Autocrine induction of invasion and metastasis by tumor-associated trypsin inhibitor in human colon cancer cells.
Cbl-b accelerates trypsin-induced cell detachment through ubiquitination and degradation of proline-rich tyrosine kinase 2.
Characterization of the cellular binding site for the urinary trypsin inhibitor.
Clinicopathologic study of 62 acinar cell carcinomas of the pancreas: insights into the morphology and immunophenotype and search for prognostic markers.
Cytogenetic evidence for premeiotic transformation of human testicular cancers.
Detection of Cancer-Specific Proteases Using Magnetic Relaxation of Peptide-Conjugated Nanoparticles in Biological Environment.
Differential expression of protease-activated receptors-1 and -2 in stromal fibroblasts of normal, benign, and malignant human tissues.
Differential expression of trypsin in human ovarian carcinomas and low-malignant-potential tumors.
Effect of LY287045, a thrombin/trypsin inhibitor, on thrombin and trypsin-induced aortic contraction and relaxation.
Effect of trypsin concentration on living SMCC-7721 cells studied by atomic force microscopy.
Epigenetic silencing of PRSS3 provides growth and metastasis advantage for human hepatocellular carcinoma.
Experimental studies on factors influencing the widespread organ distribution of Walker 256 tumour metastases.
Expression and activity analysis of a new fusion protein targeting ovarian cancer cells.
Expression of Tissue Factor Pathway Inhibitor 2 in Human Pancreatic Carcinoma and its Effect on Tumor Growth, Invasion, and Migration in vitro and in vivo.
Hepatic arterial haemodynamics changes following intra-arterial angiotensin II infusion: duplex/colour Doppler sonography.
High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer.
Identification and characterization of the cell-associated binding protein for urinary trypsin inhibitor.
Identification of novel peptide inhibitors for human trypsins.
Identification of serum amyloid A as a biomarker to distinguish prostate cancer patients with bone lesions.
Identification of sustainable trypsin active-site inhibitors from Nigrospora sphaerica strain AVA-1.
Increased serum levels of tumour-associated trypsin inhibitor independently predict a poor prognosis in colorectal cancer patients.
Inhibition of metastasis of Lewis lung carcinoma by urinary trypsin inhibitor in experimental and spontaneous metastasis models.
Inhibition of the soluble and the tumor cell receptor-bound plasmin by urinary trypsin inhibitor and subsequent effects on tumor cell invasion and metastasis.
Inhibitory effect of a conjugate between human urokinase and urinary trypsin inhibitor on tumor cell invasion in vitro.
Is There a Trojan Horse to Aggressive Pancreatic Cancer Biology? A Review of the Trypsin-PAR2 Axis to Proliferation, Early Invasion, and Metastasis.
Mixture of trypsin, chymotrypsin and papain reduces formation of metastases and extends survival time of C57Bl6 mice with syngeneic melanoma B16.
Monitoring the treatment outcome in endometrial cancer patients by CEA and TATI.
Nonrandom abnormalities in chromosome 1 in human testicular cancers.
On the latency of tumour cells.
Piperidine carbamate peptidomimetic inhibitors of the serine proteases HGFA, matriptase and hepsin.
Proinflammatory cytokines up-regulate synthesis and secretion of urinary trypsin inhibitor in human hepatoma HepG2 cells.
Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis.
Proteinase-activated receptor 2 (PAR-2) in gastrointestinal and pancreatic pathophysiology, inflammation and neoplasia.
Proteolytic activity associated with tumour growth and metastasis. Influence of trypsin inhibitor (soya bean) on Ehrlich ascites tumour growth [proceedings].
PRSS3/mesotrypsin is a therapeutic target for metastatic prostate cancer.
Suppressing effects of dietary supplementation of soybean trypsin inhibitor on spontaneous, experimental and peritoneal disseminated metastasis in mouse model.
Suppression of invasion and peritoneal carcinomatosis of ovarian cancer cell line by overexpression of bikunin.
Suppression of urokinase-type plasminogen activator expression from human ovarian cancer cells by urinary trypsin inhibitor.
TGF-?1/ALK5-mediated cell migration is dependent on the protein PAR2 but not on PAR2-stimulated Gq-calcium signaling.
The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation.
The Protease Activated Receptor2 Promotes Rab5a Mediated Generation of Pro-metastatic Microvesicles.
The role of cell membrane-associated urinary trypsin inhibitor in tumor cell invasion and metastasis.
Trypsin digest study of retinal metastasis and tumor cell emboli.
Trypsin in colorectal cancer: molecular biological mechanisms of proliferation, invasion, and metastasis.
Trypsinogen expression in human ovarian carcinomas.
Urinary trypsin inhibitor efficiently inhibits urokinase production in tumor necrosis factor-stimulated cells.
Urinary trypsin inhibitor suppresses surgical stress-facilitated lung metastasis of murine colon 26-L5 carcinoma cells.
[Two-route chemotherapy under AT-II induced hypertension using totally implanted injection port system in liver metastases derived from digestive cancers]
Neoplasm, Residual
Pre-operative serum level of tumour-associated trypsin inhibitor and residual tumour size as prognostic indicators in Stage III epithelial ovarian cancer.
Neoplasms
3D-QSAR CoMFA studies on trypsin-like serine protease inhibitors: a comparative selectivity analysis.
A bifunctional hybrid molecule of the amino-terminal fragment of urokinase and domain II of bikunin efficiently inhibits tumor cell invasion and metastasis.
A case of pancreatic mixed acinar-neuroendocrine carcinoma successfully diagnosed with endoscopic ultrasound-guided fine needle aspiration.
A comparison of the usefulness of serum measurements of CA 125, CA 50 and TATI in patients with malignant and benign gynecological pathology.
A Dual-Labeled Knottin Peptide for PET and Near-Infrared Fluorescence Imaging of Integrin Expression in Living Subjects.
A high-density tissue microarray from patients with clinically localized prostate cancer reveals ERG and TATI exclusivity in tumor cells.
A human colon adenocarcinoma xenograft--radiation response, cellular composition, and tumor disaggregation.
A novel peptide-based electrochemical biosensor for the determination of a metastasis-linked protease in pancreatic cancer cells.
A Persistent Solid Pseudopapillary Tumor of the Pancreas: Case Report and Brief Literature Review.
A potential role of bradykinin in angiogenesis and growth of S-180 mouse tumors.
A quantitative N-glycoproteomics study of cell-surface N-glycoprotein markers of MCF-7/ADR cancer stem cells.
A renal carcinoma secreting inactive renin.
A role for protease-activated receptor-2 in pancreatic cancer cell proliferation.
A soybean Kunitz trypsin inhibitor reduces tumor necrosis factor-alpha production in ultraviolet-exposed primary human keratinocytes.
A thermostable antigen associated with ovarian cancer.
A thymus cell marker in murine leukemia virus-induced lymphomas of rats.
A trypsin inhibitor from rambutan seeds with antitumor, anti-HIV-1 reverse transcriptase, and nitric oxide-inducing properties.
A tumor-suppressive role for trypsin in human cancer progression.
Acid stable trypsin inhibitor in bile.
Acinar cell carcinoma of the pancreas in childhood.
Acinar cell carcinoma of the pancreas metastatic to the ovary: a report of 4 cases.
Acinar cell cystadenocarcinoma of the pancreas: report of rare case and review of the literature.
Acinar cell cystadenoma of the pancreas in a cat.
Acinar-islet cell carcinoma presenting as insulinoma.
Activation of type IV procollagenases by human tumor-associated trypsin-2.
Adult pancreatoblastoma: Current concepts in pathology.
Aflatoxin G1 induced TNF-?-dependent lung inflammation to enhance DNA damage in alveolar epithelial cells.
Alpha 1-antitrypsin: a possible tool for diagnosis of cervical cancer.
Alpha-fetoprotein-producing acinar cell carcinoma of the pancreas.
Amiloride and urinary trypsin inhibitor inhibit urothelial cancer invasion.
An alpha 2-macroglobulinlike activity in the blood of chelicerate and mandibulate arthropods.
An immunocapture-LC-MS-based assay for serum SPINK1 allows simultaneous quantification and detection of SPINK1 variants.
An improved mouse orthotopic bladder cancer model exhibiting progression and treatment response characteristics of human recurrent bladder cancer.
An in situ electrochemical detection method of cell viability.
Angiotensin-II administration is useful for the detection of liver metastasis from pancreatic cancer during pharmacoangiographic computed tomography.
Antikeratin antibodies in tumor diagnosis. Distinction between seminoma and embryonal carcinoma.
Antimetastatic activity of a synthetic serine protease inhibitor, FOY-305 (Foypan).
Antipeptide Immunocapture with In-Sample Calibration Curve Strategy for Sensitive and Robust LC-MS/MS Bioanalysis of Clinical Protein Biomarkers in Formalin-Fixed Paraffin-Embedded Tumor Tissues.
Antiproliferative activity of Lavatera cashmeriana- protease inhibitors towards human cancer cells.
Antizyme is necessary for conversion of pancreatic tumor cells into glucagon-producing differentiated cells.
Application of Frontal Affinity Chromatography to Study the Biomolecular Interactions with Trypsin.
Assessment of the tumor-associated trypsin inhibitor (TATI) marker in patients with carcinoma of the uterine body 17 years after treatment.
Association of cystic fibrosis transmembrane conductance regulator (CFTR) mutation/variant/haplotype and tumor necrosis factor (TNF) promoter polymorphism in hyperlipidemic pancreatitis.
Association of trypsin expression with recurrence and poor prognosis in human esophageal squamous cell carcinoma.
Association of trypsin expression with tumour progression and matrilysin expression in human colorectal cancer.
Autocrine extra-pancreatic trypsin 3 secretion promotes cell proliferation and survival in esophageal adenocarcinoma.
Autocrine stimulation by prolactin of hormone-responsive breast cancer growth in culture.
Autoproteolytic stability of a trypsin from the marine crab Cancer pagurus.
Avian tumour virus interactions with chicken fibroblast membranes: partial characterization of initial attachment site activity.
Basement membrane alterations after treatment with trypsin, hyaluronidase or collagenase.
beta-Naphthylamidase activity of the cell surface of ehrlich ascites cells. Reversible control of enzyme activity by metal ions and thiols.
Bioactive Composition, Antioxidant Activity, and Anticancer Potential of Freeze-Dried Extracts from Defatted Gac (Momordica cochinchinensis Spreng) Seeds.
Biochemical and structural insights into mesotrypsin: an unusual human trypsin.
BIOCHEMICAL PROPERTIES OF CARBOXYPEPTIDASE A OF THE UNTRANSFERRED TISSUE AND MALIGNANT NEOPLASM OF THE MAMMARY GLAND.
Biology and function of tumor-associated trypsin inhibitor, TATI.
Biomarker development, from bench to bedside.
Biphasic kinetics of metal ion reactivation of trypsin-thiol complexes.
Blocking of lymphokine activated killer (LAK) cell mediated cytotoxicity by cell-sized beads bearing tumor cell proteins.
Bombesin-stimulated serum immunoreactive trypsin in the differential diagnosis between endocrine and exocrine tumors of the pancreas.
Bone and kidney adenylate cyclase-stimulating activity produced by a hypercalcemic canine adenocarcinoma line (CAC-8) maintained in nude mice.
Buckwheat trypsin inhibitor enters Hep G2 cells by clathrin-dependent endocytosis.
Cancer cell structure: actin changes in tumour cells--possible mechanisms for malignant tumour formation.
CANCER, ITS ETIOLOGY AND TREATMENT BY TRYPSIN.
Cancer-associated antigen CA 195 in patients with mucinous ovarian tumours: a comparative analysis with CEA, TATI and CA 125 in serum specimens and cyst fluids.
Cationic trypsinogen produced by human pancreatic ductal cancer has the characteristics of spontaneous activation and gelatinolytic activity in the presence of proton.
Cbl-b accelerates trypsin-induced cell detachment through ubiquitination and degradation of proline-rich tyrosine kinase 2.
Cell coat in tumor cells -- effects of trypsin and EDTA: a biochemical and morphological study.
Cell properties after repeated transplantation of spontaneously and of SV40 virus transformed mouse cell lines. I. Growth in culture.
Cell survival and growth delay in rat R-1 tumours after radiation and vinblastine treatment.
Changes in distribution of hepatic blood flow induced by intra-arterial infusion of angiotensin II in human hepatic cancer.
Changes in growth and adhesion of Ehrlich ascites tumour cells coated with trypsin inhibitor (soybean).
Changes in the collagenolytic activity released by primary VX-2 carcinoma cultures as a function of tumor growth.
Characteristics of the chemotactic response of neoplastic cells to a factor derived from the fifth component of complement.
Characterization of a CD6 ligand(s) expressed on human- and murine-derived cell lines and murine lymphoid tissues.
Characterization of a tumor-associated serine protease.
Characterization of an animal model of aggressive metastatic pheochromocytoma linked to a specific gene signature.
Characterization of mouse tumor cell beta-lipotropin.
Characterization of opioid binding sites in murine neuroblastoma.
Characterization of plasma membrane redox activity from Ehrlich cells.
Characterization of the cellular binding site for the urinary trypsin inhibitor.
Characterization of zeta (zeta): a new opioid receptor involved in growth.
Chemical transformation of Swiss mouse embryo fibroblasts in primary culture.
Chemotactic factor for tumor cells derived from the C5a fragment of complement component C5.
Cleavage of hexokinase II to two domains by trypsin without significant change in catalytic activity.
Clinical usefulness of serum acute-phase reactants in patients with ovarian tumors.
Co-Expression of a Chimeric Protease Inhibitor Secreted by a Tumor-Targeted Salmonella Protects Therapeutic Proteins from Proteolytic Degradation.
Co-expression of trypsin and tumour-associated trypsin inhibitor (TATI) in colorectal adenocarcinomas.
Collagenolytic activity by malignant tumours.
Combinatorial optimization of cystine-knot peptides towards high-affinity inhibitors of human matriptase-1.
Combinatorial protein engineering of proteolytically resistant mesotrypsin inhibitors as candidates for cancer therapy.
Comparative untargeted proteomic analysis of ADME proteins and tumor antigens for tumor cell lines.
Comparison of the surface glycoprotein components in the isolated cells of hamster melanotic and amelanotic melanomas.
Conformational changes of rBTI from buckwheat upon binding to trypsin: implications for the role of the P(8)' residue in the potato inhibitor I family.
Connective tissue degradation by invasive rat bladder carcinomas: action of nonspecific proteinases on collagenous matrices.
Controlling nonspecific trypsin cleavages in LC-MS/MS-based shotgun proteomics using optimized experimental conditions.
Could a plant derived protein potentiate the anticancer effects of a stem cell in brain cancer?
Crystal structure of cancer chemopreventive Bowman-Birk inhibitor in ternary complex with bovine trypsin at 2.3 A resolution. Structural basis of Janus-faced serine protease inhibitor specificity.
Cytogenetic evidence for premeiotic transformation of human testicular cancers.
Cytokeratin expression in cells of the rodent bile duct developing under normal and pathological conditions.
Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase beta in human endothelial cells.
Cytological findings and BCL10 expression in pancreatic acinar cell carcinoma: A Case Report.
Cytomorphologic and immunophenotypical features of acinar cell neoplasms of the pancreas.
Decreased plasma levels of cholecystokinin in healthy males after chronic ingestion of a heat-treated soya product.
Demonstration and characterization of zeta (zeta), a growth-related opioid receptor, in a neuroblastoma cell line.
Detection of Cancer-Specific Proteases Using Magnetic Relaxation of Peptide-Conjugated Nanoparticles in Biological Environment.
Detection of trypsin- and chymotrypsin-like proteases using p-nitroanilide substrates after sodium dodecyl sulphate polyacrylamide gel electrophoresis.
Detergent addition to tryptic digests and ion mobility separation prior to MS/MS improves peptide yield and protein identification for in situ proteomic investigation of frozen and formalin-fixed paraffin-embedded adenocarcinoma tissue sections.
Determination of urinary trypsin inhibitor provides insight into postoperative complications in patients following esophagectomy.
Development of a murine intravesical orthotopic human bladder cancer (mio-hBC) model.
Diabetes-enhanced tumor necrosis factor-alpha production promotes apoptosis and the loss of retinal microvascular cells in type 1 and type 2 models of diabetic retinopathy.
Diagnostic and Prognostic Potential of Biomarkers CYFRA 21.1, ERCC1, p53, FGFR3 and TATI in Bladder Cancers.
Diagnostic and prognostic value of tumor-associated trypsin inhibitor in gastrointestinal malignancies.
Differential effects of serine proteases on the migration of normal and tumor cells: implications for tumor microenvironment.
Differential expression of protease-activated receptors-1 and -2 in stromal fibroblasts of normal, benign, and malignant human tissues.
Differential expression of trypsin in human ovarian carcinomas and low-malignant-potential tumors.
Differential expression of trypsinogen and tumor-associated trypsin inhibitor (TATI) in bladder cancer.
Differential expression of tumor target binding and cytolytic activities in bone marrow culture-derived macrophages.
Differential lysis of tumor target cells displayed by lymphokine activated killer (LAK) cell clones.
Digestion of the fifth component of complement by leukocyte enzymes. Sequential generation of chemotactic activities for leukocytes and for tumor cells.
Disaggregation of human solid tumours by combined mechanical and enzymatic methods.
Disaggregation studies of xenograft solid tumors grown from pure or admixed clonal subpopulations from a heterogeneous human colon adenocarcinoma.
Dissociation of in vivo and in vitro "autonomy" in human adrenocortical tumour.
Diverse mitogenic agents induce the phosphorylation of two related 42,000-dalton proteins on tyrosine in quiescent chick cells.
DNA-binding region of the simian virus 40 tumor antigen.
Dramatic increase in serum trypsinogens, SPINK1 and hCG? in aortic surgery patients after hypothermic circulatory arrest.
Duplex/colour Doppler sonography: measurement of changes in hepatic arterial haemodynamics following intra-arterial angiotensin II infusion.
Effect of an in vitro fertilization program on serum CA 125, tumor-associated trypsin inhibitor, free beta-subunit of human chorionic gonadotropin, and common alpha-subunit of glycoprotein hormones.
Effect of crude trypsin on incorporation of 3H-thymidine and 3H-uridine into the Ehrlich ascites tumour cells.
Effect of enzymic removal of cell surface constituents on metastatic colonisation potential of mouse mammary tumour cells.
Effect of inhaled 239PuO2 on alveolar type II cells.
Effect of LY287045, a thrombin/trypsin inhibitor, on thrombin and trypsin-induced aortic contraction and relaxation.
Effect of trypsin concentration on living SMCC-7721 cells studied by atomic force microscopy.
Effect of trypsin on mouse mammary tumor virus.
Effect of tumor dissaggregation on results of in vitro cell survival assay after in vivo treatment of the EMT-6 tumor: x-rays, cyclophosphamide, and bleomycin.
Effect of ulinastatin on interleukins and pulmonary function in bypass patients: a meta-analysis of randomized controlled trials.
Effect of Ulinastatin, a human urinary trypsin inhibitor, on the oleic acid-induced acute lung injury in rats via the inhibition of activated leukocytes.
Effects of estradiol on insulin receptor distribution in primary cultures of R3230AC mammary adenocarcinoma of the rat.
Effects of radiation therapy on tissue and serum concentrations of tumour associated trypsin inhibitor and their prognostic significance in rectal cancer patients.
Effects of RU486 and indomethacin on meiotic maturation, formation of extracellular matrix, and progesterone production by porcine oocyte-cumulus complexes.
Effects of the synthetic trypsin inhibitor camostate on the development of N-nitrosobis(2-oxopropyl)amine-induced pancreatic lesions in hamsters.
Effects of trypsin on binding of insulin and concanavalin A and on glucose and proline transport in the R3230AC mammary adenocarcinoma.
Effects of trypsin on the platelet-aggregating activity of mouse tumor cells.
Effects of urinary trypsin inhibitor on the invasion of reconstituted basement membranes by ovarian cancer cells.
Efficacy of two-route chemotherapy using cis-diamminedichloroplatinum(II) and its antidote, sodium thiosulfate, in combination with angiotensin II for rat liver tumor.
Efficacy of two-route chemotherapy using cis-diamminedichloroplatinum(II) and its antidote, sodium thiosulfate, in combination with angiotensin II in a rat limb tumor.
Efficient identification of proteins from ovaries and hepatopancreas of the unsequenced edible crab, Cancer pagurus, by mass spectrometry and homology-based, cross-species searching.
Egg lectin of Rana japonica and its receptor glycoprotein of Ehrlich tumor cells.
Electron spin resonance and fluorescence observations on erythrocytes, erythrocyte membranes, 13762 MAT-A ascites adenocarcinoma cells, and their membranes, effects of membrane perturbations.
Elevated serum insulin-like growth factor-binding protein 2 (IGFBP-2) and decreased IGFBP-3 in epithelial ovarian cancer: correlation with cancer antigen 125 and tumor-associated trypsin inhibitor.
Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition.
Engineering potent mesotrypsin inhibitors based on the plant-derived cyclic peptide, sunflower trypsin inhibitor-1.
Enhanced invasiveness of pancreatic adenocarcinoma cells stably transfected with cationic trypsinogen cDNA.
Enhanced tumor localization of monoclonal antibody by treatment with kininase II inhibitor and angiotensin II.
Enkephalins in pheochromocytoma: studies in a rat model.
Enrichment of tumor cells for cell kinetic analysis in human tumor biopsies using cytokeratin gating.
Enzymatic degradation of tumor cells damaged by antibody plus complement.
Epigenetic silencing of PRSS3 provides growth and metastasis advantage for human hepatocellular carcinoma.
Epitope mapping of anti-PGRMC1 antibodies reveals the non-conventional membrane topology of PGRMC1 on the cell surface.
Establishment of a new human cancer cell line secreting protease nexin-II/amyloid beta protein precursor derived from squamous-cell carcinoma of lung.
Establishment of two vaccine-associated feline sarcoma cell lines and determination of in vitro chemosensitivity to doxorubicin and mitoxantrone.
Evaluation of TATI and other markers in solid tumors.
Evidence for metal inhibition of tumour membrane-bound neutral protease and the control of tumour-induced target cell cytolysis.
Evidence for the inhibition of trypsin by thiols. The mechanism of enzyme-inhibitor complex formation.
Evidence for the presence of a trypsin inhibitor within rabbit and mouse tumour cells.
Evidence of direct interaction between Kupffer cells and colon cancer cells: an ultrastructural study of the co-culture.
Excretion of a tumor-associated trypsin inhibitor (TATI) in urine of patients with gynecological malignancy.
Experimental studies on factors influencing the widespread organ distribution of Walker 256 tumour metastases.
Experimental study on mechanism and rarity of metastases in skeletal muscle.
Experimental trypsin-induced urothelial cell separation in vivo.
Expression of pancreatic secretory trypsin inhibitor in various cancer cells.
Expression of Tissue Factor Pathway Inhibitor 2 in Human Pancreatic Carcinoma and its Effect on Tumor Growth, Invasion, and Migration in vitro and in vivo.
Expression of trypsin in human cancer cell lines and cancer tissues and its tight binding to soluble form of Alzheimer amyloid precursor protein in culture.
Expression of trypsin in vascular endothelial cells.
Expression of tumor-associated trypsinogens (TAT-1 and TAT-2) in prostate cancer.
Familial pancreatic cancer: genetic advances.
Familial pancreatic carcinoma in Jews.
Fine needle aspiration cytology of acinar cell carcinoma of the pancreas: a report of two cases.
Flow cytometric DNA analysis of 199 histologically favourable or unfavourable non-Hodgkin lymphomas.
Functionalization of Carbon Nanomaterial Surface by Doxorubicin and Antibodies to Tumor Markers.
Further characterization of the in vitro products generated by proteolytic cleavage of Gazdar murine sarcoma virus p65gag.
Further inhibition studies on guanidinobenzoatase, a trypsin-like enzyme associated with tumour cells.
Further studies on antitumour responses induced by short-term pretreatment with syngeneic tumour cells.
Gastric carcinoma resembling pancreatic mixed acinar-endocrine carcinoma.
Generation of a recombinant Sendai virus that is selectively activated and lyses human tumor cells expressing matrix metalloproteinases.
Generation of optimized and urokinase-targeted oncolytic Sendai virus vectors applicable for various human malignancies.
Glioblastoma Stem Cells and Comparison of Isolation Methods.
Glucagon, glicentin, proglucagon, PYY, PP and proPP-icosapeptide immunoreactivities of rectal carcinoid tumors and related non-tumor cells.
Glycoprotein metabolism in skin cancer: synthesis, pool size, and partial characterization of glycoproteins in the rat basosquamous cell carcinoma.
Growth acceleration of Ehrlich ascites tumor cells treated by proteinase in vitro.
Heat-regulated expression of the hepatitis B virus surface antigen in the human Wish cell line.
Hemostasis following inoculation and during spreading of colon carcinoma in the rat.
Hepatocellular carcinoma and intermediate alpha1-antitrypsin deficiency (MZ phenotype).
Hereditary, familial, and idiopathic chronic pancreatitis are not associated with polymorphisms in the tumor necrosis factor alpha (TNF-alpha) promoter region or the TNF receptor 1 (TNFR1) gene.
Heterogeneity of cell surface structures involved in cytotoxicity mediated by lymphokine activated killer cells.
High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer.
Highly sensitive IRS based biosensor for the determination of cytochrome c as a cancer marker by using nanoporous anodic alumina modified with trypsin.
Human colon carcinoma, fibrosarcoma and leukemia cell lines produce tumor-associated trypsinogen.
Human neutrophil elastase degrades inter-alpha-trypsin inhibitor to liberate urinary trypsin inhibitor related proteins.
Human ovarian tumor-associated trypsin. Its purification and characterization from mucinous cyst fluid and identification as an activator of pro-urokinase.
Identification and characterization of the cell-associated binding protein for urinary trypsin inhibitor.
Identification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide-PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential treatment of cancer.
Identification of a Novel ITG?v?6-Binding Peptide Using Protein Separation and Phage Display.
Identification of genes up-regulated in urothelial tumors: the 67-kd laminin receptor and tumor-associated trypsin inhibitor.
Identification of novel peptide inhibitors for human trypsins.
Identification of sustainable trypsin active-site inhibitors from Nigrospora sphaerica strain AVA-1.
IL-1? is a key cytokine that induces trypsin upregulation in the influenza virus-cytokine-trypsin cycle.
Immunohistochemical analysis of pancreatic secretory trypsin inhibitor expression in pulmonary adenocarcinoma: its possible participation in scar formation of the tumor tissues.
Immunohistochemical and ultrastructural markers suggest different origins for cuboidal and polygonal cells in pulmonary sclerosing hemangioma.
Immunohistochemical characteristics and malignant progression of hepatic cystic neoplasms in comparison with pancreatic counterparts.
Immunohistochemical characterization of an amphicrine mucinous islet-cell carcinoma of the pancreas. Case report.
Immunohistochemical demonstration of pancreatic secretory trypsin inhibitor in gynecologic tumors.
Immunohistochemical localization of pancreatic secretory trypsin inhibitor in malignant pancreatic endocrine tumors.
In situ lymphoid cells of mouse mammary tumors. I. Development and evaluation of a method for the separation of lymphoid cells from mouse mammary tumors.
Increased sensitivity of murine leukemia virus-infected tumor cells to lymphocyte-mediated cytotoxicity.
Increased Serum Levels of Trypsin Inhibitor Kazal1 in Patients with HBV-Related Hepatocellular Carcinoma Predict a Poor Prognosis.
Increased serum levels of tumour-associated trypsin inhibitor independently predict a poor prognosis in colorectal cancer patients.
Increasing stability and toxicity of Pseudomonas exotoxin by attaching an antiproteasic Peptide.
Induction of colon adenocarcinomas in rats fed trypsin and tamoxifen diets by parenteral and intragastric 1,2-dimethylhydrazine.
Influence of Carbon Nanotubes and Its Derivatives on Tumor Cells In Vitro and Biochemical Parameters, Cellular Blood Composition In Vivo.
Influence of trypsin on cytostatic effects of cyclophosphamide in rats with Guerin tumours.
Influenza virus-cytokine-protease cycle in the pathogenesis of vascular hyperpermeability in severe influenza.
Inhibition of DNA synthesis by a small-cell lung carcinoma-derived protein.
Inhibition of free and bound trypsin-like enzymes.
Inhibition of growth of 3-methylcholanthrene-induced mouse skin tumor by protease inhibitor [N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)-phenylacetate] methanesulfate.
Inhibition of STAT3 signalling contributes to the antimelanoma action of atractylenolide II.
Inhibition of the soluble and the tumor cell receptor-bound plasmin by urinary trypsin inhibitor and subsequent effects on tumor cell invasion and metastasis.
Inhibition of trypsin and chymotrypsin by thiols. Biphasic kinetics of reactivation and inhibition induced by sodium periodate addition.
Inhibition of tumor cell invasion through matrigel by a peptide derived from the domain II region in urinary trypsin inhibition.
Inhibition properties of Sepharose-bound trypsin and a protease on the surface of Ehrlich ascites tumour cells.
Inhibitory activity of polysaccharide extracts from three kinds of edible fungi on proliferation of human hepatoma SMMC-7721 cell and mouse implanted S180 tumor.
Inhibitory effect of a conjugate between human urokinase and urinary trypsin inhibitor on tumor cell invasion in vitro.
Inhibitory effect of topical applications of nondenatured soymilk on the formation and growth of UVB-induced skin tumors.
Initial description of a tumor enhancing activity produced by murine splenocytes.
Initiation of human colon cancer cell proliferation by trypsin acting at protease-activated receptor-2.
Inonotus obliquus polysaccharide regulates gut microbiota of chronic pancreatitis in mice.
Inter-alpha-trypsin inhibitor bound to tumor cells is cleaved into the heavy chains and the light chain on the cell surface.
Interleukin-2 and lymphokine activated killer (LAK) cells in the treatment of malignant glioma: clinical and experimental studies.
Interleukin-8 production via protease-activated receptor 2 in human esophageal epithelial cells.
Internucleotide protein linkers in Ehrlich ascites cell DNA.
Intestinal lysosomal enzymes in the diagnosis of pancreatic disease.
Intra-arterial infusion chemotherapy with angiotensin-II for locally advanced and nonresectable pancreatic adenocarcinoma: further evaluation and prognostic implications.
Intra-Tumor Heterogeneity Revealed by Mass Spectrometry Imaging Is Associated with the Prognosis of Breast Cancer.
Intracellular co-localization of trypsin-2 and matrix metalloprotease-9: possible proteolytic cascade of trypsin-2, MMP-9 and enterokinase in carcinoma.
Intraductal tubular carcinoma, intestinal type, of the pancreas.
Intraductal Tubulopapillary Neoplasm of the Pancreas Masquerading as Pancreatic Neuroendocrine Carcinoma: Review of the Literature with a Case Report.
Intrahepatic cholangiocarcinoma in a non-cirrhotic liver in a patient with homozygous ZZ alpha-1 antitrypsin deficiency.
Intravenous injection of post-hemorrhagic shock mesenteric lymph induces multiple organ injury in rats.
Involvement of ADAMTS5 and hyaluronidase in aggrecan degradation and release from OSM-stimulated cartilage.
Is There a Trojan Horse to Aggressive Pancreatic Cancer Biology? A Review of the Trypsin-PAR2 Axis to Proliferation, Early Invasion, and Metastasis.
Isolation and characterization of a novel Bacillus thuringiensis strain expressing a novel crystal protein with cytocidal activity against human cancer cells.
Kallikrein-related peptidases and associated microRNAs as promising prognostic biomarkers in gastrointestinal malignancies.
Limited proteolysis of tumor cells increases their plasmin-binding ability.
Losartan reduces oxidative damage to renal DNA and conserves plasma antioxidant capacity in diabetic rats.
Low alpha 2-macroglobulin-proteinase complex binding: a common but not exclusive characteristic of malignant cells.
Lung adenocarcinoma-related TNF-?-dependent inflammation upregulates MHC-II on alveolar type II cells through CXCR-2 to contribute to Treg expansion.
Lymphokine activated killer (LAK) cell mediated killing of human glioma: effect of pretreating glioma with various membrane modifying agents.
Macrophage and lymphocyte potentiation of syngeneic tumor cell and host fibroblast collagenolytic activity in rats.
Maternal serum alpha-fetoprotein and epithelial tumour marker concentrations are not increased by fetal sacrococcygeal teratoma.
Matriptase expression in the normal and neoplastic mast cells.
Matrix metalloproteinase-9 promotes neutrophil migration and alveolar capillary leakage in pancreatitis-associated lung injury in the rat.
Maturation of dendritic cells from ovarian cancer patients.
Measurement of precursors for alpha-amidated hormones by radioimmunoassay of glycine-extended peptides after trypsin-carboxypeptidase B cleavage.
Measurement of urinary trypsin inhibitor in urine, plasma and cancer tissues of patients with stomach cancer.
Medullary thyroid carcinoma: ectopic production of peptides with ACTH-like, corticotrophin releasing factor-like and prolactin production-stimulating activities.
Mesenteric Lymph Drainage Alleviates Acute Kidney Injury Induced by Hemorrhagic Shock without Resuscitation.
Mesocestoides lineatus: trypsin induced development to adult mediated by Ca2+ and protein kinase C.
Mg2+- or Mn2+-dependent p-nitrophenylphosphatase activity is present in Ehrlich ascites tumor cells.
Microfluidic device for mechanical dissociation of cancer cell aggregates into single cells.
Mining the cinnabaramide biosynthetic pathway to generate novel proteasome inhibitors.
Mitogen-activated protein kinase inhibition enhances the antitumor effects of sporamin in human pancreatic cancer cells.
Mitogen-induced disorganization of capillary-like structures formed by human large vessel endothelial cells in vitro.
Mixed acinar-endocrine carcinoma arising in the ampulla of Vater.
Mixed acinar-endocrine carcinoma of the pancreas with intraductal growth into the main pancreatic duct: Report of a case.
Mixed acinar-endocrine carcinoma of the pancreas. A clinicopathological study and comparison with acinar-cell carcinoma.
Mixture of trypsin, chymotrypsin and papain reduces formation of metastases and extends survival time of C57Bl6 mice with syngeneic melanoma B16.
MMP-9 activation by tumor trypsin-2 enhances in vivo invasion of human tongue carcinoma cells.
Molecular cytogenetic pilot study on pleomorphic adenomas of salivary glands.
Murine colon adenocarcinomas: methods for selective culture in vitro.
Murine macrophage cytotoxicity induced by mastocytoma cells, cell-free mastocytoma exudates, and extracts.
Mutation analysis of the cationic trypsinogen gene in patients with pancreatic cancer.
Natural cytotoxic macrophages in the peritoneal cavity of mice.
Natural cytotoxicity in the mouse embryo: characterization of yolk sac-associated natural cytotoxic cells and their activity.
Near infrared fluorescent trypsin stabilized gold nanoclusters as surface plasmon enhanced energy transfer biosensor and in vivo cancer imaging bioprobe.
Near-Infrared Fluorescent and Magnetic Resonance Dual-Imaging Coacervate Nanoprobes for Trypsin Mapping and Targeted Payload Delivery of Malignant Tumors.
New intracellular and molecular aspects in pathophysiology of colorectal cancer.
Non-phosphorylative transglucosylation and other biochemical indices in serum and uterine myoma in women.
Non-random chromosome changes in a herpes-virus-transformed Syrian hamster cell line and its metastatic derivatives.
Nonrandom abnormalities in chromosome 1 in human testicular cancers.
Novel animal models of acute and chronic cancer pain: a pivotal role for PAR2.
Nutritional significance of lectins and enzyme inhibitors from legumes.
Observations on the histoformative capacities of tumor cells dissociated by digestion with trypsin.
Observations on the inhibition of serum and cell surface enzymes by eicosapentaenoic acid.
Oncocytic non-functioning endocrine tumor of the pancreas.
One-tube triple staining method for flow cytometric analysis of DNA ploidy and phenotypic heterogeneity of human solid tumors using single laser excitation.
Optimizing Orthotopic Bladder Tumor Implantation in a Syngeneic Mouse Model.
Oral therapy with proteolytic enzymes decreases excessive TGF-beta levels in human blood.
Overexpression of pancreatic secretory trypsin inhibitor in pancreatic cancer. Evaluation of its biological function as a growth factor.
Overexpression of tumour-associated trypsin inhibitor (TATI) enhances tumour growth and is associated with portal vein invasion, early recurrence and a stage-independent prognostic factor of hepatocellular carcinoma.
Ovulation: new factors that prepare the oocyte for fertilization.
P-selectin expression in a metastatic pancreatic tumor cell line (SUIT-2).
P-selectin mediates adhesion of platelets to neuroblastoma and small cell lung cancer.
Pancreatic acinar cell carcinoma with a ductal adenocarcinoma component: a case report and analysis of the histogenesis of the tumor.
Pancreatic acinar cell carcinoma with endocrine differentiation: immunohistochemical and ultrastructural analyses.
Pancreatic acinar cell carcinoma. An analysis of cell lineage markers, p53 expression, and Ki-ras mutation.
Pancreatic Ductal Adenocarcinoma Development in the Remnant Pancreas after Pancreaticoduodenectomy for Acinar Cell Carcinoma: A Case Report.
Pancreatic mixed acinar-neuroendocrine carcinoma, a unique diagnostic challenge on FNA cytology: A small series of two cases with literature review.
Pancreatic secretory abnormalities precede appearance of tumors of the pancreas in hamsters treated with bis-(2-oxopropyl)-N-nitrosamine.
Pancreatic secretory trypsin inhibitor from human amniotic fluid and fetal and neonatal urine: concentrations and physicochemical characterization.
Pancreatic secretory trypsin inhibitor in cancer.
Pancreatic secretory trypsin inhibitor stimulates the growth of rat pancreatic carcinoma cells.
Pancreatic secretory trypsin inhibitor-like immunoreactivity in pancreatectomized patients.
Pancreatic-type acinar cell carcinoma of the liver: a clinicopathologic study of four patients.
Papillary cystic tumor of the pancreas. An analysis of cellular differentiation by electron microscopy and immunohistochemistry.
Partial purification of human colonic carcinoma cells by sedimentation.
Pathophysiology of pulmonary complications of acute pancreatitis.
Persistent distension and enhanced diffusive extravasation of tumor vessels improved uniform tumor targeting of radioimmunoconjugate in mice administered with angiotensin II and kininase inhibitor.
Pharmacologic intervention with angiotensin II and kininase inhibitor enhanced efficacy of radioimmunotherapy in human colon cancer xenografts.
Photodynamic therapy and tumor imaging of hypericin-treated squamous cell carcinoma.
Physalaemin: an amphibian tachykinin in human lung small-cell carcinoma.
Piperidine carbamate peptidomimetic inhibitors of the serine proteases HGFA, matriptase and hepsin.
Plasminogen activator activity in clonogenic cell populations separated from a murine fibrosarcoma.
PO-44 - Tissue factor pathway inhibitor-2 (TFPI-2) is cleaved by PRSS3: implication for tumor endothelial cells migration.
Post-obstructive cyst formation in pancreas and cystic acinar transformation: Are they same?
Pre-diagnostic levels of anionic trypsinogen, cationic trypsinogen, and pancreatic secretory trypsin inhibitor in relation to pancreatic cancer risk.
Preferential digestion of basement membrane collagen by an enzyme derived from a metastatic murine tumor.
Primary acinar cell carcinoma of the liver.
Proceedings: Autoradiography of Ehrlich ascites tumours treated with soybean trypsin inhibitor in vivo.
Proceedings: Independent responses of different binding sites on ehrlich ascites tumour cells to trypsin and trypsin inhibitor.
Production of a serine-protease with macrophage migration-inhibitory factor activity by virus-transformed cells and human tumor cell lines.
Production of bone-resorbing activity and colony-stimulating activity in vivo and in vitro by a human squamous cell carcinoma associated with hypercalcemia and leukocytosis.
Production of macrophage activation factors by tryptic cleavage of calf serum proteins.
Production of soluble matriptase by human cancer cell lines and cell surface activation of its zymogen by trypsin.
Production of trypsins by human gastric cancer cells correlates with their malignant phenotype.
Proinflammatory cytokines up-regulate synthesis and secretion of urinary trypsin inhibitor in human hepatoma HepG2 cells.
Proliferative properties of the clonogenic cells of the R3327 prostate adenocarcinoma.
Promoter hypomethylation of protease-activated receptor 2 associated with carcinogenesis in the stomach.
Promotion of benign hyperplastic lesions in hamster cheek pouch by membrane labilizing agents and calcium ion: evidence that intracellular calcium-induced release from growth control is an obligatory preliminary stage of tumor promotion.
Protease inhibitor activity in human skeletal muscle.
Protease inhibitor antipain suppresses 12-O-tetradecanoyl-phorbol-13-acetate induction of plasminogen activator in transformable mouse embryo fibroblasts.
Protease-activated receptor (PAR)-1 and PAR-2 participate in the cell growth of alveolar capillary endothelium in primary lung adenocarcinomas.
Protease-activated receptor 2 in colon cancer: trypsin-induced MAPK phosphorylation and cell proliferation are mediated by epidermal growth factor receptor transactivation.
Protease-activated receptor-2 (PAR-2) in cervical cancer proliferation.
Protease-activated receptor-2 induces proinflammatory cytokine and chemokine gene expression in canine keratinocytes.
Protection against preterm delivery in mice by urinary trypsin inhibitor.
Proteinase-activated receptor 2 (PAR-2) in gastrointestinal and pancreatic pathophysiology, inflammation and neoplasia.
Proteinase-activated receptor-2-mediated signaling and inhibition of DNA synthesis in human pancreatic cancer cells.
Proteolytic activity associated with tumour growth and metastasis. Influence of trypsin inhibitor (soya bean) on Ehrlich ascites tumour growth [proceedings].
Proteome-wide analysis of head and neck squamous cell carcinomas using laser-capture microdissection and tandem mass spectrometry.
Proteomic analysis of pancreatic secretory trypsin inhibitor/tumor-associated trypsin inhibitor from urine of patients with pancreatitis or prostate cancer.
Proteomics of glycoproteins based on affinity selection of glycopeptides from tryptic digests.
PRSS3/mesotrypsin is a therapeutic target for metastatic prostate cancer.
Rapid aggregation and tight junction formation in single cell suspensions of tumor cells after very low dose trypsin treatment.
Rat mammary carcinoma cells secrete active collagenase and activate latent enzyme in the stroma via plasminogen activator.
rBTI induces apoptosis in human solid tumor cell lines by loss in mitochondrial transmembrane potential and caspase activation.
Reaction of a tumour-associated trypsin inhibitor with serine proteinases associated with coagulation and tumour invasion.
Reactive oxygen species and enzyme dual-responsive biocompatible drug delivery system for targeted tumor therapy.
Recent advances in autoimmune pancreatitis: concept, diagnosis, and pathogenesis.
Reconstructed mung bean trypsin inhibitor targeting cell surface GRP78 induces apoptosis and inhibits tumor growth in colorectal cancer.
Recovery of cell subpopulations from human tumour xenografts following dissociation with different enzymes.
Refined characterisation of chromosome aberrations in tumours by multicolour banding and electronic mapping resources.
Regulation of prostaglandin biosynthesis in dispersed choriodecidual cells in culture.
Relationship between renal function and blood level of chromogranin A.
Relationship between the changes in the concentration of endoxan and the activity of kininforming enzymes within the Guérin tumor in rat.
Release of glycolytic enzymes from cultivated tumor cells.
Release of malignancy-related fucopeptides from ascites tumour cells in association with membrane vesicles.
Renal function and serum concentration of five tumor markers (TATI, SCC, CYFRA 21-1, TPA, and TPS) in patients without evidence of neoplasia.
Renin-angiotensin system inhibitors as therapeutic alternatives in the treatment of chronic liver diseases.
Resistance of CTL to perforin-mediated lysis. Evidence for a lymphocyte membrane protein interacting with perforin.
Response of an in vivo-in vitro tumour to X-rays and cytotoxic drugs: effect of tumour disaggregation method on cell survival.
Response to hormones of cells cultured from human giant cell tumors of bone.
RNA inhibits estrogen receptor binding to DNA.
Role of angiotensin II in liver fibrosis-induced portal hypertension and therapeutic implications.
Role of bile and trypsin in the release of cholecystokinin in humans.
Role of Intrapancreatic SPINK1/Spink3 Expression in the Development of Pancreatitis.
Role of the tumor-associated trypsin inhibitor SPINK1 in cancer development.
Role of trypsin and protease-activated receptor-2 in ovarian cancer.
Role of urinary trypsin inhibitor in the maintenance of pregnancy in mice.
Roles of serine protease inhibitor Kazal type 1 (SPINK1) in pancreatic diseases.
Secretagogue response of azaserine-induced rat pancreatic acinar tumors in vivo.
Selection by trypsin of two sublines of rat colon cancer cells forming progressive or regressive tumors.
Sequence and conformational specificity in substrate recognition: several human Kunitz protease inhibitor domains are specific substrates of mesotrypsin.
Serine peptidase inhibitor Kazal type III (SPINK3) promotes BRL-3A cell proliferation by targeting the PI3K-AKT signaling pathway.
Serine protease inhibitor Kazal type 1 (SPINK1) as a prognostic marker in stage IV colon cancer patients receiving cetuximab based targeted therapy.
Serum alpha-1 proteinase inhibitor in advanced cancer: mass variants and functionally inert forms.
Serum carcinoembryonic antigen, cancer antigen 125, cancer antigen 15-3, squamous cell carcinoma, and tumor-associated trypsin inhibitor concentrations during healthy pregnancy.
Serum immunoreactive trypsin concentration after a Lundh meal. Its value in the diagnosis of pancreatic disease.
Serum levels of tumor associated trypsin inhibitor (TATI) and glomerular filtration rate.
Serum levels of tumor-associated trypsin inhibitor (TATI) in benign and malignant gynecological diseases.
Serum tumor markers CEA, CA 50, TATI, and NSE in lung cancer screening.
Serum tumour associated trypsin inhibitor, as a biomarker for survival in renal cell carcinoma.
Serum tumour-associated trypsin inhibitor (TATI) and renal function.
Simian virus 40 tumor antigen: isolation of the origin-specific DNA-binding domain.
Small molecule inhibitors of mesotrypsin from a structure-based docking screen.
Sodium butyrate improved intestinal immune function associated with NF-?B and p38MAPK signalling pathways in young grass carp (Ctenopharyngodon idella).
Specificity profiling of human trypsin-isoenzymes.
SPINK1 is a prognosis predicting factor of non-small cell lung cancer and regulates redox homeostasis.
Sporamin suppresses growth of xenografted colorectal carcinoma in athymic BALB/c mice by inhibiting liver ?-catenin and vascular endothelial growth factor expression.
Squamous cell carcinoma antigen, tumor associated trypsin inhibitor and tissue polypeptide specific antigen in follow up of stage III cervical cancer.
Steroid sequestration and tightly bound oestrogen-protein complexes in human breast tumours and a breast cancer cell line.
Stimulation of cellular growth and adhesion to fibronectin and vitronectin in culture and tumorigenicity in nude mice by overexpression of trypsinogen in human gastric cancer cells.
Stimulation of reactive oxygen species production and cytotoxicity in human neutrophils in vitro and after oral administration of a polyenzyme preparation.
Structure and function analysis of urinary trypsin inhibitor (UTI): identification of binding domains and signaling property of UTI by analysis of truncated proteins.
Studies on the molecular composition and degradation of type IV procollagen.
SUBSTANCES AFFECTING ADULT TISSUE IN VITRO : I. THE STIMULATING ACTION OF TRYPSIN ON FRESH ADULT TISSUE.
Suppression of invasion and peritoneal carcinomatosis of ovarian cancer cell line by overexpression of bikunin.
Suppression of lipopolysaccharide-induced cytokine production of gingival fibroblasts by a soybean, Kunitz trypsin inhibitor.
Suppression of the renin-angiotensin system attenuates vascular endothelial growth factor-mediated tumor development and angiogenesis in murine hepatocellular carcinoma cells.
Suppression of urokinase-type plasminogen activator expression from human ovarian cancer cells by urinary trypsin inhibitor.
Symplocamide A, a potent cytotoxin and chymotrypsin inhibitor from the marine Cyanobacterium Symploca sp.
Synthesis and biological characterization of protease-activated prodrugs of doxazolidine.
Systemic chemotherapy in tumor-bearing rats using high-dose cis-diamminedichloroplatinum(II) with low nephrotoxicity in combination with angiotensin II and sodium thiosulfate.
Targeting an Oncolytic Influenza A Virus to Tumor Tissue by Elastase.
TATI (tumor associated trypsin inhibitor) and cancer antigen 125 (CA 125) in patients with early-stage endometrial cancer.
TGF-?1/ALK5-mediated cell migration is dependent on the protein PAR2 but not on PAR2-stimulated Gq-calcium signaling.
The cytologic and immunohistochemical findings of pancreatic mixed acinar-endocrine carcinoma.
The effect of anionic detergents and trypsin on mitochondria of normal and tumour tissues.
The effect of intra-arterial angiotensin II on the hepatic tumor to non-tumor blood flow ratio for radioembolization: a systematic review.
The effect of trypsin and neuraminidase on the circulation and organ distribution of tumor cells.
The Effect of Trypsin on Cancer and on the Germ Cells in Mice.
The effects of ionizing irradiation on the sedimentation coefficient of cytoplasmic steroid receptors in rat mammary tumors.
The feasibility of storing ovarian tumor cells on databasing paper: establishing a library of ovarian cancer DNA.
The G-banding pattern of chromosomes in Ehrlich Lettŕe ascites tumor cells.
The incidence of pulmonary tumors in mice exposed to aerosols of therapeutic agents; an evaluation of the possible carcinogenic properties of penicillin, pyribenzamine, adrenalin, cortisone, trypsin and desoxyribonuclease.
The interaction of a trypsin-dependent neutral protease and its inhibitor found in tumour cells. Analysis of complex kinetic data involved in a thiol-disulphide exchange mechanism.
The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation.
The Morama Bean (Tylosema esculentum) A Potential Crop for Southern Africa.
The P2' residue is a key determinant of mesotrypsin specificity: Engineering a high affinity inhibitor with anticancer activity.
The prevalence of pancreatic acinar differentiation in gastric adenocarcinoma: report of a case and immunohistochemical study of 111 additional cases.
The Protease Activated Receptor2 Promotes Rab5a Mediated Generation of Pro-metastatic Microvesicles.
The relationship between serum tumor-associated trypsin inhibitor levels and clinicopathological parameters in patients with gastric cancer.
The relative values of serum immuno-reactive trypsin concentration and total amylase activity in the diagnosis of mumps, chronic renal failure, and pancreatic disease.
The role of cell membrane-associated urinary trypsin inhibitor in tumor cell invasion and metastasis.
The widely-distributed tumour protein, oncomodulin, is a normal constituent of human and rodent placentas.
Thermally self-assembled biodegradable poly(casein-g-N-isopropylacrylamide) unimers and their application in drug delivery for cancer therapy.
Three-dimensional Alginate-bead Culture of Human Pituitary Adenoma Cells.
Time-resolved immunofluorometric assay of trypsin-1 complexed with alpha(1)-antitrypsin in serum: increased immunoreactivity in patients with biliary tract cancer.
Tissue disaggregation of human renal cell carcinoma with further isopyknic and isokinetic gradient purification.
Tissue-cultured head and neck tumors: their use in in vitro assays of immune response.
TNF-?-dependent lung inflammation upregulates superoxide dismutase-2 to promote tumor cell proliferation in lung adenocarcinoma.
TPA, TATI, CEA, AFP, beta-HCG, PSA, SCC, and CA 19-9 for monitoring transitional cell carcinoma of the bladder.
Transient expression of high molecular weight, heat sensitive, trypsin-resistant form of tyrosinase in B-16 melanoma cells.
Transplantation of azaserine-induced carcinomas of pancreas in rats.
Triple stimuli-responsive keratin nanoparticles as carriers for drug and potential nitric oxide release.
Trophoblastic apoptosis in mice with preterm delivery and its suppression by urinary trypsin inhibitor.
TRYPSIN AND EREPSIN IN CANCER.
Trypsin digest study of retinal metastasis and tumor cell emboli.
Trypsin enhances aptamer screening: A novel method for targeting proteins.
TRYPSIN IN CANCER.
TRYPSIN IN CANCER: A PRELIMINARY STATEMENT.
Trypsin in colorectal cancer: molecular biological mechanisms of proliferation, invasion, and metastasis.
Trypsin induces tumour necrosis factor-alpha secretion from a human leukemic mast cell line.
Trypsin inhibitor activity in commercial soybean products in Japan.
Trypsin inhibitor in the serum in pregnancy and chorionic neoplasia.
Trypsin is produced by and activates protease-activated receptor-2 in human cancer colon cells: evidence for new autocrine loop.
Trypsin stimulates integrin alpha(5)beta(1)-dependent adhesion to fibronectin and proliferation of human gastric carcinoma cells through activation of proteinase-activated receptor-2.
Tumor associated trypsin inhibitor and CA-125 during treatment of mucinous ovarian cancer in 2 patients.
Tumor associated trypsin inhibitor as a prognostic factor in renal cell carcinoma.
Tumor growth inhibition mediated by trypsin inhibitor or urokinase inhibitors.
Tumor markers CA 125, carcinoembryonic antigen and tumor-associated trypsin inhibitor in patients with cervical adenocarcinoma.
Tumor-associated trypsin inhibitor (TATI) and cancer antigen 125 (CA125) in patients with epithelial ovarian cancer.
Tumor-associated trypsin inhibitor (TATI) and renal function.
Tumor-associated trypsin inhibitor (TATI) and tumor-associated trypsin-2 (TAT-2) predict outcomes in gastric cancer.
Tumor-Associated Trypsin Inhibitor (TATI) as a Biomarker of Poor Prognosis in Oropharyngeal Squamous Cell Carcinoma Irrespective of HPV Status.
Tumor-associated trypsin inhibitor (TATI) in bone diseases.
Tumor-associated trypsin inhibitor and cancer antigen 125 in pelvic masses.
Tumor-associated trypsin inhibitor in induced and acquired immunodeficiency. Studies on transplanted and HIV-infected patients.
Tumor-associated trypsin inhibitor.
Tumor-associated trypsin participates in cancer cell-mediated degradation of extracellular matrix.
Tumor-host interactions in the rabbit V2 carcinoma: stimulation of cathepsin B in host fibroblasts by a tumor-derived cytokine.
Tumor-targeted and nitric oxide-generated nanogels of keratin and hyaluronan for enhanced cancer therapy.
Tumour-associated trypsin inhibitor (TATI) and cancer antigen 125 (CA 125) in mucinous ovarian tumours.
Tumour-associated trypsin inhibitor and tumour-associated trypsin.
Tumour-associated trypsin inhibitor in the diagnosis of pancreatic carcinoma.
Tumour-associated trypsin inhibitor TATI is a prognostic marker in colorectal cancer.
Tumour-associated trypsin inhibitor, carcinoembryonic antigen and acute-phase reactant proteins CRP and alpha1-antitrypsin in patients with gastrointestinal malignancies.
Two rare cases of a solid pseudopapillary neoplasm of the pancreas.
Unique insight into microenvironmental changes in colorectal cancer: Ex vivo assessment of matrix metalloprotease-mediated molecular changes in human colorectal tumor tissue and corresponding non-neoplastic adjacent tissue.
Urinary immunoreactive trypsin excretion: a non-invasive screening test for pancreatic cancer.
Urinary trypsin inhibitor (UTI) and fragments derived from UTI by limited proteolysis efficiently inhibit tumor cell invasion.
Urinary trypsin inhibitor efficiently inhibits urokinase production in tumor necrosis factor-stimulated cells.
Urinary trypsin inhibitor levels in the urine of patients with haematological malignancies.
Urinary trypsin inhibitor reduces LPS-induced hypotension by suppressing tumor necrosis factor-alpha production through inhibition of Egr-1 expression.
Urinary trypsin inhibitor, a Kunitz-type protease inhibitor, modulates tumor necrosis factor-stimulated activation and translocation of protein kinase C in U937 cells.
Urinary trypsin inhibitory activity for the diagnosis of bacterial infection: a prospective study in 690 patients.
Urinary trypsin inhibitory capacity determination: study in patients with disseminated cancers.
Validation and comparison of tumor-associated trypsin inhibitor (TATI) immunoassays.
Variables influencing cell binding assays for antibody binding kinetics.
Vascular architecture as a diagnostic marker for differentiation of World Health Organization thymoma subtypes and thymic carcinoma.
Vascular sarcomas (probably angiosarcomas) transplanted from suspensions of liver cells from diethylnitrosamine-treated rats.
Versican-A Critical Extracellular Matrix Regulator of Immunity and Inflammation.
[5-FU concentration in the tissue of gastric cancer, and evaluation of cancer chemotherapy with angiotensin-II]
[A case of non-resectable pancreatic cancer surviving more than 4 years by intra-arterial infusion chemotherapy with angiotensin-II]
[An effect of the intra-arterial infusion of angiotensin II in the chemotherapy of human hepatic cancer]
[Association between natural cell mediated cytotoxicity (NCMC) and serum factors in acute leukemia and other malignant diseases]
[CASES OF CANCER OF VATER'S AMPULLA TREATED WITH KALLIKREIN AND TRYPSIN INACTIVATOR (TRASYLOL).]
[Changes in blood enzyme activity and tumor necrosis factor level in the treatment of experimental pancreatitis with pentoxifylline]
[Clinical evaluation of tumor-associated trypsin inhibitor (TATI) in benign and malignant gynecological tumor]
[Clinical significance of pancreatic secretory trypsin inhibitor assay as a tumor marker]
[Clinicopathologic characterisitics of pancreatic acinar cell carcinomas].
[Determination of the mitotic index in tumors by using cell suspensions]
[Effect of synthetic protease inhibitor on the oncogenesis of pancreatic cancer in hamsters: study on pancreatic endocrine cells and free radicals]
[Experimental study of tumor directed therapy with gastric cancer monoclonal antibody-mitomycin conjugate combined with propranolol or angiotensin II]
[Expression of trypsin and cancer proliferation in colorectal neoplasms]
[Laboratory diagnosis of pancreatitis and pancreatic cancer]
[Mechanism of tumor cell-induced extracellular matrix degradation--inhibition of cell-surface proteolytic activity might have a therapeutic effect on tumor cell invasion and metastasis]
[Pancreatic secretory trypsin inhibitor in urothelial cancer]
[Possibility of improving cytological diagnosis by applying trypsin on lesions of the cervix uteri suspected of malignancy]
[Preparation of tumor cells from human lung cancer tissue for the purpose of cloning]
[Production of enzymes and enzyme inhibitors in neoplastic tissues]
[Proteolytic enzymes and their inhibitors in the tumors and blood serum of patients with breast neoplasms]
[Purification and study of the characteristics of the multinucleated giant cells of the giant cell tumor]
[Radioimmunologic analysis of trypsin and C-peptide tumor markers for evaluation of treatment efficiency in patients with pancreatic and Vater's ampulla cancer]
[Responses of cytokines, acute phase proteins, and polymorphonuclear cell elastase to surgical stress in the patients with esophageal cancer]
[Significance of the the tumor markers, Ca-125 and tumor-associated trypsin inhibitor in patients with carcinoma of the cervix and uterus]
[Specific proteinases in the urine of cancer patients. Comparative studies with modified Abderhalden reaction and a quantitative trypsin color test]
[Studies on platelet aggregation induced by human cultured carcinoma cell lines]
[Study of plasminogen activator and trypsin inhibitor in gastric cancer, ulcer and experimental tumor.]
[Successful Surgical Resection of Expansive-Growth Acinar Cell Carcinoma-A Case Report].
[The diagnostic significance of pancreatic secretory trypsin inhibitor (PSTI) in patients with gynecologic tumors]
[The effect of glycolytic enzymes on the metabolism of tumor cells. V. Proteolytic activation of fructose1,6-diphosphatase with trypsin.]
[The expression of trypsin in serum and vital organs of septic rats].
[The hypertensive effect induced with angiotensin II and the physiological and pharmacokinetic aspects of two-route chemotherapy using CDDP and STS]
[The relationship between opsonin, endotoxin and chemical mediators in postoperative complications after surgery]
[The significance of determination of urinary trypsin inhibitor related antigen in patients with cancer of the digestive organs]
[Tissue polypeptide antigen and tumor trypsin inhibitor in pleural effusions of various etiologies]
[Trypsin resistance of natural and heat-treated cells; studies with leukocytes and ascites tumor cells of mice.]
[Tumor vascularity under hypertension induced by intravenous infusion of angiotensin II--angiographic and radionuclide angiographic observations]
[Tumor-associated trypsin inhibitor--an expanded tumor marker spectrum in cervix cancer?]
[Two-route chemotherapy under AT-II induced hypertension using totally implanted injection port system in liver metastases derived from digestive cancers]
[Urinary trypsin inhibitor in cancer patients]
Nephritis
Nephrotoxic serum nephritis in rats. II. Preparation and characterization of a soluble protective factor produced by trypsin digestion of rat tissue homogenates.
[Comparison of the trypsin inhibitor activity in urine of donors and patients with kidney diseases]
Nephritis, Hereditary
Trypsin digestion on paraffin sections is a useful tool for diagnosis of alport syndrome.
Nephrosis
Urine protease and antiprotease activity in experimental aminonucleoside nephrotoxicity.
Nephrotic Syndrome
Use of buccal trypsin in two diabetics with the nephrotic syndrome: a preliminary report.
[Concentration of acid-stable inhibitors--metabolites of plasma inter-alpha trypsin inhibitor--in the urine of healthy people and in patients with nephrotic syndrome]
Neuralgia
The effect of urinary trypsin inhibitor against neuropathic pain in rat models.
Urinary trypsin inhibitor attenuates the development of neuropathic pain following spinal nerve ligation.
Neuralgia, Postherpetic
[Experience in treating a herpetic infection with trypsin]
Neuroblastoma
A novel developmentally regulated gene in lung mesenchyme: homology to a tumor-derived trypsin inhibitor.
Characterization of cysteine proteases functioning in degradation of dynorphin in neuroblastoma cells: evidence for the presence of a novel enzyme with strict specificity toward paired basic residues.
Enhancement of neurite outgrowth in PC12h cells by a protease inhibitor.
Evidence that neutral sphingomyelinase of cultured murine neuroblastoma cells is oriented externally on the plasma membrane.
Identification of galectin-3-binding protein as a factor secreted by tumor cells that stimulates interleukin-6 expression in the bone marrow stroma.
Membrane-bound trypsin-like enzyme functioning in degradation of dynorphin in neuroblastoma cells. Purification and characterization.
P-selectin mediates adhesion of platelets to neuroblastoma and small cell lung cancer.
[Influenza encephalopathy and encephalitis]
[Surface charge of mouse neuroblastoma cells and changes during growth and morphologic differentiation of the cell population]
Neurogenic Inflammation
Cathepsin S causes inflammatory pain via biased agonism of PAR2 and TRPV4.
Evidence for the role of neurogenic inflammation components in trypsin-elicited scratching behaviour in mice.
Neurogenic components of trypsin- and thrombin-induced inflammation in rat skin, in vivo.
Potentiation of the P2X3 ATP receptor by PAR-2 in rat dorsal root ganglia neurons, through protein kinase-dependent mechanisms, contributes to inflammatory pain.
Protease-activated receptor 2 expression in trigeminal neurons innervating the rat nasal mucosa.
Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain.
Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia.
Neuroinflammatory Diseases
Essential role of mitogen-activated protein kinase pathways in protease activated receptor 2-mediated nitric-oxide production from rat primary astrocytes.
Neuromyelitis Optica
Retinal pathologic changes in multiple sclerosis.
Urinary trypsin inhibitor levels are reduced in cerebrospinal fluid of multiple sclerosis and neuromyelitis optica patients during relapse.
Neuronal Ceroid-Lipofuscinoses
Neuronal ceroid lipofuscinosis. A retinal trypsin digest study.
Neurosyphilis
[On the association of trypsin and penicillin in the therapy of neurosyphilis.]
Neutropenia
A case of Shwachman-Diamond syndrome confirmed with genetic analysis in a Korean child.
Neutrophil-dependent decrease in early wound margin strength.
Nevus
Autologous skin reconstruction by combining epidermis and acellular dermal matrix tissue derived from the skin of giant congenital melanocytic nevi.
Newcastle Disease
A regular subunit pattern seen on non-infectious Newcastle disease virus particles.
Plaque formation of Newcastle disease virus in primary chicken kidney cells.
Recombinant lentogenic Newcastle disease virus expressing Ebola virus GP infects cells independently of exogenous trypsin and uses macropinocytosis as the major pathway for cell entry.
[Effect of proteolytic enzymes on the enhanced sensitivity of a cell culture of goat embryonic kidney to Newcastle disease virus]
Non-alcoholic Fatty Liver Disease
Dietary wheat amylase trypsin inhibitors promote features of murine non-alcoholic fatty liver disease.
Noonan Syndrome
De Novo Duplication of Chromosome 9p in a Female Infant: Phenotype and Genotype Correlation.
Nutrition Disorders
[Trypsin and diastase in acute nutritional disorders in infants.]
Obesity
Anti-TNF-? Agent Tamarind Kunitz Trypsin Inhibitor Improves Lipid Profile of Wistar Rats Presenting Dyslipidemia and Diet-induced Obesity Regardless of PPAR-? Induction.
Biochemical characterisation of a Kunitz-type inhibitor from Tamarindus indica L. seeds and its efficacy in reducing plasma leptin in an experimental model of obesity.
Citrin deficiency as a cause of chronic liver disorder mimicking non-alcoholic fatty liver disease.
Digestive enzyme inhibitors from grains as potential components of nutraceuticals.
Recombinant buckwheat trypsin inhibitor decreases fat accumulation via the IIS pathway in Caenorhabditis elegans.
Serum proteomic biomarker discovery reflective of stage and obesity in breast cancer patients.
Structural insights and molecular dynamics into the inhibitory mechanism of a Kunitz-type trypsin inhibitor from Tamarindus indica L.
Structure-Activity Relationship and Molecular Docking of a Kunitz-Like Trypsin Inhibitor, Kunitzin-AH, from the Skin Secretion of Amolops hainanensis.
Tamarind Trypsin Inhibitor in Chitosan-Whey Protein Nanoparticles Reduces Fasting Blood Glucose Levels without Compromising Insulinemia: A Preclinical Study.
Trypsin inhibitor from tamarindus indica L. seeds reduces weight gain and food consumption and increases plasmatic cholecystokinin levels.
Trypsin inhibitors: promising candidate satietogenic proteins as complementary treatment for obesity and metabolic disorders?
[Exocrine function of the pancreas in children]
Obstetric Labor, Premature
Antenatal microbiologic and maternal risk factors associated with prematurity.
Effect of urinary trypsin inhibitor on preterm labor with high granulocyte elastase concentration in cervical secretions.
Effects of urinary trypsin inhibitor in patients at risk for premature labor with a bulging fetal membrane.
Effects of urinary trypsin inhibitor on myometrial contraction in term and preterm deliveries.
Re-evaluation of Urinary Trypsin Inhibitor on Pregnancy Course in Patients with Threatened Preterm Delivery: A Single-Center Retrospective Study.
Urinary trypsin inhibitor: a new drug to treat preterm labor: a comparative study with ritodrine.
Osteoarthritis
Effect of urinary trypsin inhibitor on osteoarthritis.
Efficacy of Bromelain along with Trypsin, Rutoside Trihydrate Enzymes and Diclofenac Sodium Combination Therapy for the treatment of TMJ Osteoarthritis - A Randomised Clinical Trial.
Human and bovine articular cartilage loading measured with a new resistive sensor: effects of protease degradation and osteoarthritis.
Multicomponent analysis of T1 relaxation in bovine articular cartilage at low magnetic fields.
Oral enzyme combination versus diclofenac in the treatment of osteoarthritis of the knee--a double-blind prospective randomized study.
Trypsin-induced mitosis in the articular cartilage of adult rabbits.
Osteolysis
Staphylococcus epidermidis produces a cell-associated proteinaceous fraction which causes bone resorption by a prostanoid-independent mechanism: relevance to the treatment of infected orthopaedic implants.
Osteomyelitis
[Treatment of chronic osteomyelitis by intra-focal administration of antibiotics with trypsin.]
Osteoporosis
Isolation of therapeutically functional mouse bone marrow mesenchymal stem cells within 3 h by an effective single-step plastic-adherent method.
Osteosarcoma
Enhancement of production of IgM and interferon-beta in human cell lines by poly-lysine.
Isolation and identification of cancer stem cells from human osteosarcom by serum-free three-dimensional culture combined with anticancer drugs.
Tumor-associated trypsin inhibitor (TATI) in bone diseases.
Otitis
[Rational methods of use of trypsin in the treatment of chronic otitis (experimental studies)]
Otitis Externa
[The use of trypsin and lysozyme immobilized on a cellulose carrier in treating otitis externa]
Otitis Media with Effusion
Serous otitis media; treatment with injectable trypsin.
Otosclerosis
Objective changes in trypsin, alpha 1-antitrypsin, and alpha 2-macroglobulin values as a result of sodium fluoride treatment in patients with otosclerosis.
[The genetics of the protease inhibitor system and osteospongiosis. Statistical study in 199 patients]
Out-of-Hospital Cardiac Arrest
Insufficient production of urinary trypsin inhibitor for neutrophil elastase release after cardiac arrest.
Ovarian Cysts
MUC-6 mucin is a major component of "blood group substance" from human ovarian cyst fluid.
Tumour-associated trypsin inhibitor (TATI) in human ovarian cyst fluid. Comparison with CA 125 and CEA.
Ovarian Diseases
Clinical usefulness of serum acute-phase reactants in patients with ovarian tumors.
Ovarian Hyperstimulation Syndrome
The Higher Response of Vascular Endothelial Growth Factor and Angiotensin-II to Human Chorionic Gonadotropin in Women with Polycystic Ovary Syndrome.
Ovarian Neoplasms
A novel proteomic biomarker panel as a diagnostic tool for patients with ovarian cancer.
A soybean Kunitz trypsin inhibitor suppresses ovarian cancer cell invasion by blocking urokinase upregulation.
Classification of cancer types by measuring variants of host response proteins using SELDI serum assays.
Clinical use of gynaecologic tumour markers.
Effect of intracavitary radiotherapy on tumor-associated trypsin inhibitor (TATI) in patients with cervical and endometrial cancer.
Effects of urinary trypsin inhibitor on the invasion of reconstituted basement membranes by ovarian cancer cells.
Emerging Roles of SPINK1 in Cancer.
Expression and activity analysis of a new fusion protein targeting ovarian cancer cells.
Expression of trypsinogen-1, trypsinogen-2, and tumor-associated trypsin inhibitor in ovarian cancer: prognostic study on tissue and serum.
Markers supplementing CA 125 in ovarian cancer.
Pancreatic secretory trypsin inhibitor from human amniotic fluid and fetal and neonatal urine: concentrations and physicochemical characterization.
Preoperative serum concentration of hCGbeta as a prognostic factor in ovarian cancer.
Preparation of Mitochondria from Ovarian Cancer Tissues and Control Ovarian Tissues for Quantitative Proteomics Analysis.
Proteomic biomarkers for overall and progression-free survival in ovarian cancer patients.
Purification and characterization of a tumor-associated trypsin inhibitor from the urine of a patient with ovarian cancer.
Role of serum-derived hyaluronan-associated protein-hyaluronan complex in ovarian cancer.
Role of trypsin and protease-activated receptor-2 in ovarian cancer.
Suppressing effects of dietary supplementation of soybean trypsin inhibitor on spontaneous, experimental and peritoneal disseminated metastasis in mouse model.
Suppression of urokinase-type plasminogen activator expression from human ovarian cancer cells by urinary trypsin inhibitor.
TATI (tumour-associated trypsin inhibitor) as a marker of ovarian cancer.
The differentially mitochondrial proteomic dataset in human ovarian cancer relative to control tissues.
The feasibility of storing ovarian tumor cells on databasing paper: establishing a library of ovarian cancer DNA.
The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation.
Tumor associated trypsin inhibitor and CA-125 during treatment of mucinous ovarian cancer in 2 patients.
Tumor-associated trypsin inhibitor.
Tumour-associated trypsin inhibitor (TATI) in ovarian cancer.
Tumour-associated trypsin inhibitor (TATI): comparison with CA125 as a preoperative prognostic indicator in advanced ovarian cancer.
Urinary trypsin inhibitor (UTI) and fragments derived from UTI by limited proteolysis efficiently inhibit tumor cell invasion.
Validation and comparison of tumor-associated trypsin inhibitor (TATI) immunoassays.
[Determination of tumor-associated trypsin inhibitor (TATI) in subjects with gastrointestinal diseases. Preliminary data]
Overweight
Trypsin inhibitors: promising candidate satietogenic proteins as complementary treatment for obesity and metabolic disorders?
[Effect of a reducing diet on metabolic disorders in ischemic heart disease patients having excess weight]
Pancreatic Diseases
13C-egg white breath test: a non-invasive test of pancreatic trypsin activity in the small intestine.
Activities of gamma-glutamyl transferase, 5'-nucleotidase and alkaline phosphatase in human duodenal aspirate.
An elevated ratio of serum anionic to cationic trypsinogen may signal pancreatic disease.
Biology and function of tumor-associated trypsin inhibitor, TATI.
Can plasma human pancreatic polypeptide be used to detect diseases of the exocrine pancreas?
Clinical evaluation of a serum trypsin determination method in pancreatic disease.
Clinical significance of serum pancreatic enzymes in the quiescent phase of chronic pancreatitis.
Clinical value of serum immunoreactive trypsin concentration.
Coenzyme-Mediated Electro-RAFT Polymerization for Amplified Electrochemical Interrogation of Trypsin Activity.
Concentration of immunoreactive trypsin and activity of pancreatic isoamylase in serum compared in pancreatic diseases.
Diagnostic accuracy of serum cationic trypsinogen estimation for pancreatic diseases.
Diagnostic value of fecal chymotrypsin and trypsin assessment for detection of pancreatic disease. A comparative study.
Elastase-1 vs trypsin, lipase and amylase serum levels in pancreatic diseases.
Elevated serum levels of immunoreactive anionic trypsin (but not cationic trypsin) signals pancreatic disease.
Elimination of trypsin inhibitor activity and beany flavor in soy milk by consecutive blanching and ultrahigh-temperature (UHT) processing.
Enzyme measurements in the investigation of pancreatic diseases.
Human anionic trypsinogen: properties of autocatalytic activation and degradation and implications in pancreatic diseases.
Immunohistochemical localization of pancreatic secretory trypsin inhibitor in fetal and adult pancreatic and extrapancreatic tissues.
Increased interdigestive pancreatic trypsin secretion in alcoholic pancreatic disease.
Intestinal activities of trypsin, lipase, and phospholipase after a test meal. An evaluation of 474 examinations.
MEASUREMENT OF TRYPSIN AND CHYMOTRYPSIN ACTIVITY IN STOOLS TO DETECT CHRONIC PANCREATIC DISEASE.
Normal duodenal trypsin values in response to secretin-pancreozymin stimulation with preliminary data in patients with pancreatic disease.
Phenotypic changes in mouse pancreatic stellate cell Ca2+ signaling events following activation in culture and in a disease model of pancreatitis.
Present and future trends in selected areas of clinical enzymology.
Protease amperometric sensor.
Radioimmunoassay for human pancreatic secretory trypsin inhibitor: measurement of serum pancreatic secretory trypsin inhibitor in normal subjects and subjects with pancreatic diseases.
Relationship between PABA and Lundh tests: lack of influence of duodenal pH in vivo.
Remote biosensor for the determination of trypsin by using nanoporous anodic alumina as a three-dimensional nanostructured material.
Renal factors in serum trypsinogen 1 metabolism and excretion in chronic pancreatic disease.
Renal handling of amylase and immunoreactive trypsin in pancreatic cancer and chronic pancreatitis.
Renal involvement in chronic pancreatic disease: effects on trypsin and amylase plasma-urine transfer.
Serum elastase 1 and immunoreactive trypsin in chronic pancreatic disease: is there any relationship with trypsin inhibitors?
Serum elastase 1 in chronic pancreatic disease.
Serum immunoreactive trypsin concentration after a Lundh meal. Its value in the diagnosis of pancreatic disease.
Serum pancreatic enzymes in the elderly.
Serum pancreatic secretory trypsin inhibitor in pancreatic disease.
Serum trypsin binding activity in patients with pancreatic diseases.
Serum trypsin determination in pancreatic disease.
Serum trypsin; a new diagnostic test for pancreatic disease.
SPINK1/PSTI mutations are associated with tropical pancreatitis in Bangladesh. A preliminary report.
Stimulation with cholecystokinin leads to increased ratio between mRNA levels for anionic and cationic trypsinogen in rat pancreas.
Subcutaneous fat necrosis associated with pancreatic disease.
The diagnostic value of faecal trypsin estimation in chronic pancreatic disease.
The heat-induced protein aggregate correlated with trypsin inhibitor inactivation in soymilk processing.
The measurement of serum immunoreactive pancreatic secretory trypsin inhibitor in gastrointestinal cancer and pancreatic disease.
The relative values of serum immuno-reactive trypsin concentration and total amylase activity in the diagnosis of mumps, chronic renal failure, and pancreatic disease.
The secretin-CCK test and a modified Lundh test. A comparative study.
The usefulness of trypsin determination in the serum in the diagnosis of pancreatic diseases in children.
Thr28, Nle31 CCK-9--an useful CCK analogue in stimulation tests of pancreatic exocrine function.
Trypsin activity. A new marker of acute alcoholic pancreatitis.
Trypsin and chymotrypsin as aids in the diagnosis of pancreatic disease.
Trypsin and chymotrypsin determinations in human duodenal aspirate under the influence of continuous secretin-pancreozymin stimulation as an aid in the diagnosis of pancreatic disease.
Trypsin and elastase-1 in chronic pancreatic diseases.
Trypsin and lactoferrin levels in pure pancreatic juice in patients with pancreatic disease.
Trypsin clearance and pancreatic disease.
Trypsin/creatinine clearance ratio and serum immunoreactive trypsin in digestive and pancreatic diseases.
Tumor-associated trypsin inhibitor in pancreatic diseases.
Tumor-associated trypsin inhibitor in patients with chronic pancreatic diseases.
[Changes in the serum pancreas enzyme following i.v. stimulation with secretin in subjects with a normal pancreas]
[Clinical usefulness of a trypsin radioimmunoassay kit]
[Determination of serum levels of trypsin in the diagnosis of pancreatic diseases]
[Diagnosis of pancreatic disease (radioimmunological method for trypsin levels in blood]
[Diagnostic significance of serum immunoreactive trypsin in pancreatic diseases (author's transl)]
[Diagnostic value of chymotrypsin and trypsin activity determination in the feces in the diagnosis of pancreatic disease]
[Diagnostic value of serum immunoreactive trypsin assay in pancreatic diseases using enzyme immunoassay]
[Immunotrypsinogen and amylase isoenzymes in pancreatic diseases]
[Serum pancreatic secretory trypsin inhibitor (PSTI), amylase activity and pancreatic isoamylase activity in pancreatic diseases]
[Serum trypsin inhibitor and trypsin binding protein in pancreatic diseases]
[Studies on ribonuclease in the pancreatic juice of patient with pancreatic disease. II. Secretory pattern of ribonuclease, amylase and immunoreactive trypsin in duodenal juice during pancreozymin secretin test]
[Value of pancreatic secretory trypsin inhibitor by radioimmunoassay in diagnosis of pancreatic diseases]
[Value of the radioimmunologic measurement of serum trypsin in the study of pancreatic diseases. Preliminary studies]
Pancreatic Fistula
Pancreatic Inflammation and Proenzyme Activation Are Associated With Clinically Relevant Postoperative Pancreatic Fistulas After Pancreas Resection.
The effect of SST, glucagon, calcitonin and PGE1 on exocrine pancreatic secretion in the unrestrained dog in long-term experiments.
Pancreatic Neoplasms
A role for protease-activated receptor-2 in pancreatic cancer cell proliferation.
Action of antiproteases on pancreatic cancer cells.
Can plasma human pancreatic polypeptide be used to detect diseases of the exocrine pancreas?
Cell lineage markers in human pancreatic cancer.
CFTR, SPINK1, PRSS1, and CTRC Mutations Are Not Associated With Pancreatic Cancer in German Patients.
Clinical value of serum immunoreactive trypsin concentration.
Deoxyribonuclease I serum activity in pancreatic cancer.
Designing protease sensors for real-time imaging of trypsin activation in pancreatic cancer cells.
Effect of synthetic protease inhibitor on histologic changes and free radical activity in hamsters with pancreatic cancer.
Elevated serum levels of immunoreactive anionic trypsin (but not cationic trypsin) signals pancreatic disease.
Establishment of a human pancreatic cancer cell line and detection of pancreatic cancer associated antigen.
Familial pancreatic cancer: genetic advances.
Familial pancreatic carcinoma in Jews.
Fractional urinary clearance of immunoreactive lipase in chronic pancreatic disease.
Functional analysis of a pancreatic secretory trypsin inhibitor-like protein in insects: silencing effects resemble the human pancreatic autodigestion phenotype.
Hereditary pancreatitis and mutation of the trypsinogen gene.
Hereditary pancreatitis and pancreatic carcinoma.
Hereditary pancreatitis as the premalignant disease: a Japanese case of pancreatic cancer involving the SPINK1 gene mutation N34S.
Human anionic trypsinogen: properties of autocatalytic activation and degradation and implications in pancreatic diseases.
Intestinal lysosomal enzymes in the diagnosis of pancreatic disease.
Is There a Trojan Horse to Aggressive Pancreatic Cancer Biology? A Review of the Trypsin-PAR2 Axis to Proliferation, Early Invasion, and Metastasis.
Marginal zinc status does not exacerbate pancreatic carcinogenesis associated with dietary soybean trypsin inhibitor concentrate in rats.
Molecular advances in pancreatic cancer.
Molecular signatures of sanguinarine in human pancreatic cancer cells: A large scale label-free comparative proteomics approach.
Molecular size distribution of immunoreactive trypsin and renal tubular dysfunction: role in trypsin plasma-urine transfer.
Mutation analysis of the cationic trypsinogen gene in patients with pancreatic cancer.
Novel mutations of PRSS1 gene in patients with pancreatic cancer among Han population.
Overexpression of pancreatic secretory trypsin inhibitor in pancreatic cancer. Evaluation of its biological function as a growth factor.
Pre-diagnostic levels of anionic trypsinogen, cationic trypsinogen, and pancreatic secretory trypsin inhibitor in relation to pancreatic cancer risk.
Protease-activated receptor-2 expression and the role of trypsin in cell proliferation in human pancreatic cancers.
PRSS1 mutation: a possible pathomechanism of pancreatic carcinogenesis and pancreatic cancer.
PRSS1 mutations and the proteinase/antiproteinase imbalance in the pathogenesis of pancreatic cancer.
PRSS3 expression is associated with tumor progression and poor prognosis in epithelial ovarian cancer.
PRSS3/mesotrypsin is a therapeutic target for metastatic prostate cancer.
Reactive oxygen species and enzyme dual-responsive biocompatible drug delivery system for targeted tumor therapy.
Renal factors in serum trypsinogen 1 metabolism and excretion in chronic pancreatic disease.
Renal handling of amylase and immunoreactive trypsin in pancreatic cancer and chronic pancreatitis.
Renal tubular dysfunction in pancreatic cancer and chronic pancreatitis.
Roles of pancreatic stellate cells in pancreatic inflammation and fibrosis.
Serum elastase 1 and immunoreactive trypsin in chronic pancreatic disease: is there any relationship with trypsin inhibitors?
Serum elastase 1 in chronic pancreatic disease.
Serum immunoreactive trypsin concentration after a Lundh meal. Its value in the diagnosis of pancreatic disease.
Serum trypsin and TCR as novel markers for predicting disease activity in IgG4-related disease.
Signal of proteinase-activated receptor-2 contributes to highly malignant potential of human pancreatic cancer by up-regulation of interleukin-8 release.
The -409 C/T genotype of PRSS1 protects against pancreatic cancer in the Han Chinese population.
The effect of corn trypsin inhibitor, anti-tissue factor pathway inhibitor antibodies and phospholipids on microvesicle-associated thrombin generation in patients with pancreatic cancer and healthy controls.
The P2' residue is a key determinant of mesotrypsin specificity: Engineering a high affinity inhibitor with anticancer activity.
The relative values of serum immuno-reactive trypsin concentration and total amylase activity in the diagnosis of mumps, chronic renal failure, and pancreatic disease.
Time-resolved immunofluorometric assay of trypsin-1 complexed with alpha(1)-antitrypsin in serum: increased immunoreactivity in patients with biliary tract cancer.
Trypsin and lactoferrin levels in pure pancreatic juice in patients with pancreatic disease.
Trypsin-protease activated receptor-2 signaling contributes to pancreatic cancer pain.
Trypsin/creatinine clearance ratio and serum immunoreactive trypsin in digestive and pancreatic diseases.
Tumor-associated trypsin inhibitor in patients with chronic pancreatic diseases.
Tumour-associated trypsin inhibitor in the diagnosis of pancreatic carcinoma.
Tumour-associated trypsin inhibitor, TATI, in patients with pancreatic cancer, pancreatitis and benign biliary diseases.
Urinary enzymes excretion in pancreatic diseases. Clinical role and pathophysiological considerations.
Urinary immunoreactive trypsin excretion: a non-invasive screening test for pancreatic cancer.
Urinary immunoreactive trypsin in pancreatic cancer.
[Effect of synthetic protease inhibitor on the oncogenesis of pancreatic cancer in hamsters: study on pancreatic endocrine cells and free radicals]
[Laboratory diagnosis of pancreatitis and pancreatic cancer]
[Radioimmunologic analysis of trypsin and C-peptide tumor markers for evaluation of treatment efficiency in patients with pancreatic and Vater's ampulla cancer]
Pancreatic Pseudocyst
Pancreatic pseudocysts: a biochemical evaluation of proteases and protease inhibitors in plasma.
The treatment of chronic recurrent pancreatitis with depot secretin--a preliminary report.
Pancreaticobiliary Maljunction
Activated pancreatic enzyme and pancreatic stone protein (PSP/reg) in bile of patients with pancreaticobiliary maljunction/ choledochal cysts.
Two cases of chronic pancreatitis associated with anomalous pancreaticobiliary ductal union and SPINK1 mutation.
Pancreatitis
"Loss of function" mutations in the cationic trypsinogen gene (PRSS1) may act as a protective factor against pancreatitis.
"Tryptic-like" activity in sera of patients with pancreatitis.
A 93 year old man with the PRSS1 R122H mutation, low SPINK1 expression, and no pancreatitis: insights into phenotypic non-penetrance.
A carbon nanoparticle-peptide fluorescent sensor custom-made for simple and sensitive detection of trypsin.
A case of acute pancreatitis associated with cationic trypsinogen N29T mutation.
A case of hemosuccus pancreaticus associated with hereditary pancreatitis.
A CGC>CAT gene conversion-like event resulting in the R122H mutation in the cationic trypsinogen gene and its implication in the genotyping of pancreatitis.
A method for determination of immunoreactive trypsin in complex with alpha 1-antitrypsin in human sera.
A mouse model of hereditary pancreatitis generated by transgenic expression of R122H trypsinogen.
A new experimental model for gallstone pancreatitis: short-termed pancreatico-biliary duct obstruction and exocrine stimulation with systemic hypotension in rats.
A new polymorphism for the RI22H mutation in hereditary pancreatitis.
A novel A121T mutation in human cationic trypsinogen associated with hereditary pancreatitis: functional data indicating a loss-of-function mutation influencing the R122 trypsin cleavage site.
A novel thermosensitive in-situ gel of gabexate mesilate for treatment of traumatic pancreatitis: An experimental study.
A Paper-Based Near-Infrared Optical Biosensor for Quantitative Detection of Protease Activity Using Peptide-Encapsulated SWCNTs.
A possible mechanism for gallstone pancreatitis: repeated short-term pancreaticobiliary duct obstruction with exocrine stimulation in rats.
A preclinical model of chronic pancreatitis driven by trypsinogen autoactivation.
A proinflammatory, antiapoptotic phenotype underlies the susceptibility to acute pancreatitis in cystic fibrosis transmembrane regulator (-/-) mice.
A signal peptide cleavage site mutation in the cationic trypsinogen gene is strongly associated with chronic pancreatitis.
A somatostatin analogue is protective against retrograde bile salt-induced pancreatitis in the rat.
A SPINK1 gene mutation in a Thai patient with fibrocalculous pancreatic diabetes.
A study on the activation peptide released from procarboxypeptidase B (CAPAP) and anionic trypsinogen in patients with acute abdominal disorders of non-pancreatic origin.
A unique case of breast carcinoma producing pancreatic-type isoamylase.
Ablative surgery for necrotizing pancreatitis.
Acetaldehyde decreases the antitryptic activity of alpha 1-proteinase inhibitor.
Activated protein C in severe acute pancreatitis without sepsis? Not just yet ...
Activation of the complement cascade by trypsin.
Activation of trypsinogen in experimental models of acute pancreatitis in rats.
Activation peptide of carboxypeptidase B and anionic trypsinogen as early predictors of the severity of acute pancreatitis.
Active pancreatic digestive enzymes show striking differences in their potential to damage isolated rat pancreatic acinar cells.
Acute Acinar Pancreatitis Blocks Vesicle-Associated Membrane Protein 8 (VAMP8)-Dependent Secretion Resulting in Intracellular Trypsin Accumulation.
Acute pancreatitis in Soweto, South Africa: relationship between trypsinogen load, trypsinogen activation, and fibrinolysis.
Acute pancreatitis.
Acute pancreatitis: etiology and common pathogenesis.
Acute pancreatitis: proteinase-activated receptor-2 as Dr. Jekyll and Mr. Hyde.
Alcoholic pancreatitis: new pathogenetic insights.
Alteration and role of heat shock proteins in acute pancreatitis.
Alterations in intestinal function in acute pancreatitis in an experimental model.
An evaluation of the use of bile, bile salts, and trypsin in the production of experimental pancreatitis.
An integrated liquid crystal sensing device assisted by the surfactant-embedded smart hydrogel.
Analysis of the hereditary pancreatitis-associated cationic trypsinogen gene mutations in exons 2 and 3 by enzymatic mutation detection from a single 2.2-kb polymerase chain reaction product.
Analysis of tumour necrosis factor alpha and interleukin 10 promotor variants in patients with chronic pancreatitis.
Antimetastatic activity of a synthetic serine protease inhibitor, FOY-305 (Foypan).
Antiproteinase chemotherapy of acute experimental pancreatitis using the low molecular weight oligopeptide aldehyde leupeptin.
Application of molecular imaging combined with genetic screening in diagnosing MELAS, diabetes and recurrent pancreatitis.
Application of proteomic technology in identifying pancreatic secretory trypsin inhibitor variants in urine of patients with pancreatitis.
Aprotinin in severe acute pancreatitis.
Association of cystic fibrosis transmembrane conductance regulator (CFTR) mutation/variant/haplotype and tumor necrosis factor (TNF) promoter polymorphism in hyperlipidemic pancreatitis.
Association of rare chymotrypsinogen C (CTRC) gene variations in patients with idiopathic chronic pancreatitis.
Associations between gastrointestinal humoral factors and pancreatic proteolytic enzymes in alcohol-related versus non-alcohol-related pancreatitis.
ATTITUDE OF TRYPSIN INHIBITOR AT ACUTE PANCREATITIS.
Autophagic cell death of pancreatic acinar cells in serine protease inhibitor Kazal type 3-deficient mice.
Beneficial effect of therapeutic infusion of nafamostat mesilate (FUT-175) on hemodynamics in experimental acute pancreatitis.
Beneficial effects of the synthetic trypsin inhibitor camostate in cerulein-induced acute pancreatitis in rats.
Beneficial effects of trypsin inhibitors derived from a spider venom peptide in L-arginine-induced severe acute pancreatitis in mice.
Binding of 125I-labeled proteinases to plasma proteins in cystic fibrosis.
Biochemical Evaluation of the Antioxidant Effects of Hydroxytyrosol on Pancreatitis-Associated Gut Injury.
Biochemical pathways of acute lung injury.
BLOCKADE OF MULTIDRUG RESISTANCE ASSOCIATED PROTEINS AGGRAVATES ACUTE PANCREATITIS AND BLUNTS ATRIAL NATRIURETIC FACTOR BENEFITIAL EFFECT IN RATS: ROLE OF MRP4/ABCC4.
Blocking of monocyte chemoattractant protein-1 (MCP-1) activity attenuates the severity of acute pancreatitis in rats.
Calcium signaling of pancreatic acinar cells in the pathogenesis of pancreatitis.
Candesartan mediates microcirculation in acute necrotizing pancreatitis.
Cathepsin B Activates Human Trypsinogen 1 but Not Proelastase 2 or Procarboxypeptidase B.
Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice.
Cationic trypsinogen mutations and pancreatitis.
Cerulein-induced in vitro activation of trypsinogen in rat pancreatic acini is mediated by cathepsin B.
CFTR and cationic trypsinogen mutations in idiopathic pancreatitis and neonatal hypertrypsinemia.
Changes in gene expression of pancreatitis-associated protein and pancreatic secretory trypsin inhibitors in experimental pancreatitis produced by pancreatic duct occlusion in rats: comparison with gene expression of cholecystokinin and secretin.
Characterisation of a transgenic mouse expressing R122H human cationic trypsinogen.
Characterization of dsRNA-induced pancreatitis model reveals the regulatory role of IFN regulatory factor 2 (Irf2) in trypsinogen5 gene transcription.
Characterization of novel genetic alterations in salivary gland secretory carcinoma.
Characterization of phospholipase A2 activity in aspirates of human pancreatic pseudocysts after isolation by reversed-phase high performance liquid chromatography.
Cholecystokinin induces caspase activation and mitochondrial dysfunction in pancreatic acinar cells. Roles in cell injury processes of pancreatitis.
Chronic pancreatitis associated with an activation peptide mutation that facilitates trypsin activation.
Chronic pancreatitis associated with the p.G208A variant of PRSS1 gene in a European patient.
Chronic Pancreatitis in the 21st Century - Research Challenges and Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop.
Chronic pancreatitis.
Chymotrypsin C (caldecrin) promotes degradation of human cationic trypsin: identity with Rinderknecht's enzyme Y.
Chymotrypsin Reduces the Severity of Secretagogue-Induced Pancreatitis in Mice.
Cimetidine treatment in acute experimental pancreatitis.
Citrin deficiency as a cause of chronic liver disorder mimicking non-alcoholic fatty liver disease.
Clinical and genetic characteristics of hereditary pancreatitis in Europe.
Clinical characterization of patients with hereditary pancreatitis and mutations in the cationic trypsinogen gene.
Clinical interpretation of PRSS1 variants in patients with pancreatitis.
Combined Bicarbonate Conductance-Impairing Variants in CFTR and SPINK1 Are Associated with Chronic Pancreatitis in Patients without Cystic Fibrosis.
Comparative studies on the analysis of urinary trypsin inhibitor (ulinastatin) preparations.
Comparison of elastase-1 with amylase, lipase, and trypsin-like immunoreactivity in the diagnosis of acute pancreatitis.
Compartmentalization of the protease-antiprotease balance in early severe acute pancreatitis.
Comprehensive screening of chymotrypsin C (CTRC) gene in tropical calcific pancreatitis identifies novel variants.
Concentration of tissue angiotensin II increases with severity of experimental pancreatitis.
Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo.
Continuous peritoneal dialysis in acute experimental pancreatitis in dogs. Effect of aprotinin in the dialysate medium.
Contribution of the CFTR gene, the pancreatic secretory trypsin inhibitor gene (SPINK1) and the cationic trypsinogen gene (PRSS1) to the etiology of recurrent pancreatitis.
Copy number variations in chronic pancreatitis.
Correlation among complement activation, protease inhibitors, and clinical course in acute pancreatitis in man.
Correlation of pancreatic enzyme levels with the patient's recovery from acute edematous pancreatitis.
Correlation of trypsin-plasma inhibitor complexes with mortality in experimental pancreatitis in rats.
Critical care of the patient with acute pancreatitis.
Curcumin ameliorates ethanol and nonethanol experimental pancreatitis.
Current usage status of somatostatin and its analogs and trypsin inhibitors: a real-world study of 34,654 Chinese adult patients with acute pancreatitis.
Cystic fibrosis gene mutations and pancreatitis risk: relation to epithelial ion transport and trypsin inhibitor gene mutations.
Cytokine suppressive agent improves survival rate in rats with acute pancreatitis of closed duodenal loop.
Dantrolene Mitigates Caerulein-Induced Pancreatitis in vivo in Mice.
Defective binding of SPINK1 variants is an uncommon mechanism for impaired trypsin inhibition in chronic pancreatitis.
Deficiency of cathepsin C ameliorates severity of acute pancreatitis by reduction of neutrophil elastase activation and cleavage of E-cadherin.
Degradation and inactivation of plasma tumor necrosis factor-alpha by pancreatic proteases in experimental acute pancreatitis.
Deletion of TRPC3 in mice reduces store-operated Ca2+ influx and the severity of acute pancreatitis.
Diagnosis and management of acute pancreatitis.
Diagnosis and Management of Chronic Pancreatitis: A Review.
Diagnostic value of immunoreactive phospholipase A2 in acute pancreatitis.
Differences in time course of hepatocyte and pancreocyte damage after incubation with trypsin, chymotrypsin and 2.4-dinitrophenol.
Different patterns in immunoreactive anionic and cationic trypsinogen in urine and serum in human acute pancreatitis.
Digesting new information about the role of trypsin in pancreatitis.
Disruption of Small GTPase Rab7 Exacerbates the Severity of Acute Pancreatitis in Experimental Mouse Models.
Do plasma and urine trypsinogen activation peptides (TAP) really increase in trypsin-taurocholate-induced pancreatitis?
Does antecedent ethanol intake affect course of taurocholate pancreatitis in rats?
Does heparin modify protease-antiprotease balance in acute experimental pancreatitis in rats.
Dramatic increase in serum trypsinogens, SPINK1 and hCG? in aortic surgery patients after hypothermic circulatory arrest.
Early activation of endoplasmic reticulum stress is associated with arginine-induced acute pancreatitis.
Early complement system activation and neutrophil priming in acute pancreatitis: participation of trypsin.
Early events in acute pancreatitis.
Early intra-acinar events in Pathogenesis of Pancreatitis.
Early prediction of severity in acute pancreatitis. Is this possible?
Early sequential changes in serum markers of acute pancreatitis induced by endoscopic retrograde cholangiopancreatography.
Early trypsin activation develops independently of autophagy in caerulein-induced pancreatitis in mice.
Early-Onset Acute Recurrent and Chronic Pancreatitis Is Associated with PRSS1 or CTRC Gene Mutations.
Effect of a new synthetic protease inhibitor on beta-endorphin release during acute pancreatitis in dogs.
Effect of a new synthetic trypsin inhibitor on taurocholate-induced acute pancreatitis in rats.
Effect of a new trypsin inhibitor in the therapy of experimental pancreatitis.
Effect of a synthetic protease inhibitor (Fut-175) on coagulation abnormalities during experimental acute pancreatitis in dogs.
Effect of acute pancreatitis on pulmonary transvascular fluid and protein exchange.
Effect of camostate administration for two weeks on experimental pancreatitis in mice and rats.
Effect of chronic ethanol feeding on pancreatic enzyme secretion in rats in vitro.
Effect of FOY-305 (camostate) on severe acute pancreatitis in two experimental animal models.
Effect of hemorrhagic and nortriptyline-induced shock on the porcine pancreas as evaluated by changes in serum cationic trypsin-like immunoreactivity.
Effect of intravenous and intraduodenal administration of Escherichia coli endotoxin on the porcine pancreas as evaluated by changes in the serum cationic trypsin-like immunoreactivity.
Effect of oral administration of AZD8309, a CXCR2 antagonist, on the severity of experimental pancreatitis.
Effect of parenteral and early intrajejunal nutrition on pancreatic digestive enzyme synthesis, storage and discharge in dog models of acute pancreatitis.
Effect of plasma exchange on acute pancreatitis.
Effect of SMS201-995 (a long-acting somatostatin analog) on bile-induced acute hemorrhagic pancreatitis in the dog.
Effect of temporary ischemia upon development and histological patterns of acute pancreatitis in the rat.
Effect of urinary trypsin inhibitor on pancreatic cellular and lysosomal fragility in cerulein-induced acute pancreatitis in rats.
Effect on hemodynamics of therapeutic infusion of gabexate mesilate (FOY) in experimental acute pancreatitis.
Effectiveness of normal saline solution, dextran 40 or dextran 75, and aprotinin (Trasylol) on renal blood flow preservation during acute canine pancreatitis.
Effects of a bradykinin receptor antagonist (HOE140) on taurocholate-induced acute pancreatitis in rats.
Effects of a new cholecystokinin antagonist, TS-941, on experimental acute pancreatitis in rats.
Effects of a newly synthesized pancreatic protease inhibitor (PATM) on pancreatic microcirculation in experimental acute pancreatitis.
Effects of bradykinin receptor antagonist on the release of beta-endorphin and bradykinin and on hemodynamic changes in a canine model of experimental acute pancreatitis.
Effects of high-volume continuous hemofiltration on experimental pancreatitis associated lung injury in pigs.
Effects of pancreatic duct ligation on pancreatic response to bombesin.
Effects of protease inhibitor pretreatment on hemodynamic performances and survival rate in experimental, acute pancreatitis.
Effects of somatostatin on acute pancreatitis induced in rats by injection of taurocholate and trypsin into a temporarily closed duodenal loop.
Effects of urinary trypsin inhibitor on pancreatic enzymes and experimental acute pancreatitis.
Effects on peritoneal proteolysis and hemodynamics of prophylactic infusion with C1 inhibitor in experimental acute pancreatitis.
Elastase 3B mutation links to familial pancreatitis with diabetes and pancreatic adenocarcinoma.
Electrochemically controlled grafting of polymers for ultrasensitive electrochemical assay of trypsin activity.
Elevated intracellular trypsin exacerbates acute pancreatitis and chronic pancreatitis in mice.
Elevated levels of trypsinogen-2 and trypsin-2-alpha1-antitrypsin in sera of infants and children after cardiac surgery.
Elevated serum trypsin binding activity in patients with hereditary pancreatitis.
Emblica officinalis: a novel therapy for acute pancreatitis--an experimental study.
Emerging Roles of SPINK1 in Cancer.
Endoplasmic reticulum stress is activated in acute pancreatitis.
Endoscopic management of obstructive pancreatitis with a metal stent in two family members with hereditary cationic trypsinogen (PRSS1) deficiency.
Engineering mouse cationic trypsinogen for rapid and selective activation by cathepsin B.
Enteral feeding without pancreatic stimulation.
Enterokinase induced pancreatitis: its prevention with Trasylol and soybean trypsin inhibitor.
Ethanol augments elevated-[Ca2+]C induced trypsin activation in pancreatic acinar zymogen granules.
Etiology and Risk Factors of Acute and Chronic Pancreatitis.
EVALUATION OF A TRYPSIN INHIBITOR IN THE THERAPY OF PANCREATITIS.
Evaluation of the cationic trypsinogen gene for potential mutations in miniature schnauzers with pancreatitis.
Evidence for extraluminal trypsinogen activation in three different models of acute pancreatitis.
Evidence of intracellular activation of serine proteases in acute cerulein-induced pancreatitis in rats.
Evolution of serum amylase, lipase and immunoreactive trypsin during pancreatitis attacks.
Exclusion of anionic trypsinogen and mesotrypsinogen involvement in hereditary pancreatitis without cationic trypsinogen gene mutations.
Exocrine function of caerulein-induced acute pancreatitis in anesthetized rats.
Exocrine pancreatic function (serum immunoreactive trypsin, fecal chymotrypsin, and pancreatic isoamylase) in Indian diabetics.
Exocrine pancreatic function, fecal fat, and blood glucose in patients with pancreatitis.
Exocrine pancreatic secretion in acute experimental pancreatitis.
Experimental acute pancreatitis induced by excessive doses of caerulein in rats; protective and therapeutic effects of trypsin inhibitor urinastatin and CCK receptor antagonist CR1392.
Experimental acute pancreatitis--a quantification of dynamics at enzymic and histomorphologic levels.
Experimental pancreatitis in the dog. Appearance of complexes between proteases and trypsin inhibitors in ascitic fluid, lymph, and plasma.
Experimental pancreatitis in the dog. Demonstration of trypsin in ascitic fluid, lymph and plasma.
Experimental pancreatitis in the rat. Light and electron microscopical observations on early pancreatic lesions induced by intraductal injection of trypsin, phospholipase A2, lysolecithin and non-ionic detergent.
Expression of human cationic trypsinogen (PRSS1) in murine acinar cells promotes pancreatitis and apoptotic cell death.
Expression of mutated cationic trypsinogen reduces cellular viability in AR4-2J cells.
Expression of the adhesion molecules Mac-1 and L-selectin on neutrophils in acute pancreatitis is protease- and complement-dependent.
Failure of a potent trypsin inhibitor to modify experimental pancreatitis in dogs: p-aminobenzamidine.
Familial pancreatic carcinoma in Jews.
Fox sign in a case of terminal stage pancreatic cancer and suggestions for diagnosis.
Framework for interpretation of trypsin-antitrypsin imbalance and genetic heterogeneity in pancreatitis.
FRET-based modified graphene quantum dots for direct trypsin quantification in urine.
From acute to chronic pancreatitis: the role of mutations in the pancreatic secretory trypsin inhibitor gene.
Functional analysis of a pancreatic secretory trypsin inhibitor-like protein in insects: silencing effects resemble the human pancreatic autodigestion phenotype.
Functional analysis of recombinant pancreatic secretory trypsin inhibitor protein with amino-acid substitution.
Functional effects of 13 rare PRSS1 variants presumed to cause chronic pancreatitis.
Further evidence for endothelin as an important mediator of pancreatic and intestinal ischemia in severe acute pancreatitis.
Gabexate mesilate (FOY) protects against ceruletide-induced acute pancreatitis in the rat.
Gabexate mesylate inhibition of serine proteases: thermodynamic and computer-graphics analysis.
Gain-of-function mutations associated with hereditary pancreatitis enhance autoactivation of human cationic trypsinogen.
Gene Conversion between Cationic Trypsinogen (PRSS1) and the Pseudogene Trypsinogen 6 (PRSS3P2) in Patients with Chronic Pancreatitis.
Gene conversion-like missense mutations in the human cationic trypsinogen gene and insights into the molecular evolution of the human trypsinogen family.
Genes, cloned cDNAs, and proteins of human trypsinogens and pancreatitis-associated cationic trypsinogen mutations.
Genetic Abnormalities in Pancreatitis: An Update on Diagnosis, Clinical Features, and Treatment.
Genetic analysis of the glutathione s-transferase genes MGST1, GSTM3, GSTT1, and GSTM1 in patients with hereditary pancreatitis.
Genetic aspects of chronic pancreatitis: insights into aetiopathogenesis and clinical implications.
Genetic background is different between sentinel and recurrent acute pancreatitis.
Genetic background of pancreatitis.
Genetic basis of chronic pancreatitis.
Genetic Evaluation of Children with Idiopathic Recurrent Acute Pancreatitis.
Genetic factors in pancreatitis.
Genetic issues in pediatric pancreatitis.
Genetic mutations in exons 3 and 4 of the pancreatic secretory trypsin inhibitor in patients with pancreatitis.
Genetic risk in chronic pancreatitis: the misfolding-dependent pathway.
Genetic susceptibility factors for alcohol-induced chronic pancreatitis.
Genetic testing in acute and chronic pancreatitis.
Genetics and Alcohol: A Lethal Combination in Pancreatic Disease?
Genetics and pancreatic disease.
Genetics of acute and chronic pancreatitis: An update.
Genetics of chronic pancreatitis.
Genetics of pancreatitis: the 2014 update.
Glucagon treatment of experimental acute pancreatitis.
Hemin-activated macrophages home to the pancreas and protect from acute pancreatitis via heme oxygenase-1 induction.
Hereditary pancreatitis amlodipine trial: a pilot study of a calcium-channel blocker in hereditary pancreatitis.
Hereditary pancreatitis and familial pancreatic cancer.
Hereditary pancreatitis and mutation of the trypsinogen gene.
Hereditary pancreatitis and mutations of the cationic trypsinogen gene.
Hereditary pancreatitis and pancreatic carcinoma.
Hereditary pancreatitis and secondary screening for early pancreatic cancer.
Hereditary pancreatitis as the premalignant disease: a Japanese case of pancreatic cancer involving the SPINK1 gene mutation N34S.
Hereditary pancreatitis caused by a double gain-of-function trypsinogen mutation.
Hereditary pancreatitis caused by a novel PRSS1 mutation (Arg-122 --> Cys) that alters autoactivation and autodegradation of cationic trypsinogen.
Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: a novel disease mechanism.
Hereditary pancreatitis caused by triplication of the trypsinogen locus.
Hereditary pancreatitis for the endoscopist.
Hereditary pancreatitis in children: surgical implications with special regard to genetic background.
Hereditary pancreatitis in Japan: a review of pancreatitis-associated gene mutations.
Hereditary pancreatitis in North America: the Pittsburgh-Midwest Multi-Center Pancreatic Study Group Study.
Hereditary pancreatitis in Paediatrics: the causative role of p.Leu104Pro mutation of cationic trypsinogen gene also in young subjects.
Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene.
Hereditary pancreatitis-associated mutation asn(21) --> ile stabilizes rat trypsinogen in vitro.
Hereditary pancreatitis.
Hereditary pancreatitis. Gene defects and their implications.
Hereditary pancreatitis: a model for understanding the genetic basis of acute and chronic pancreatitis.
Hereditary pancreatitis: clinical characteristics and diagnostic criteria in Japan.
Hereditary pancreatitis: clinical features and inheritance characteristics of the R122C mutation in the cationic trypsinogen gene (PRSS1) in six Spanish families.
Hereditary pancreatitis: new insights, new directions.
High Incidence of PRSS1 and SPINK1 Mutations in Korean Children With Acute Recurrent and Chronic Pancreatitis.
High-affinity Ca(2+) binding inhibits autoactivation of rat trypsinogen.
Histone Deacetylase Regulates Trypsin Activation, Inflammation, and Tissue Damage in Acute Pancreatitis in Mice.
Human acute pancreatitis: its pathogenesis in the light of immunocytochemical and ultrastructural findings in acinar cells.
Human anionic trypsinogen: properties of autocatalytic activation and degradation and implications in pancreatic diseases.
Human cationic trypsinogen (PRSS1) variants and chronic pancreatitis.
Human cationic trypsinogen. Arg(117) is the reactive site of an inhibitory surface loop that controls spontaneous zymogen activation.
Human cationic trypsinogen. Role of Asn-21 in zymogen activation and implications in hereditary pancreatitis.
Human mesotrypsin defies natural trypsin inhibitors: from passive resistance to active destruction.
Human mesotrypsin is a unique digestive protease specialized for the degradation of trypsin inhibitors.
Human pancreatic secretory trypsin inhibitor in the assessment of the severity of acute pancreatitis. A comparison with C-reactive protein.
Human urinary trypsin inhibitor, urinastatin, prevents pancreatic injuries induced by pancreaticobiliary duct obstruction with cerulein stimulation and systemic hypotension in the rat.
Hypothyroidism with elevated pancreatic amylase and lipase without clinical symptoms: A case report.
Identification of a novel pancreatitis-associated missense mutation, R116C, in the human cationic trypsinogen gene (PRSS1).
Identification of CFTR, PRSS1, and SPINK1 mutations in 381 patients with pancreatitis.
Identification of sustainable trypsin active-site inhibitors from Nigrospora sphaerica strain AVA-1.
Immune-compromised state in the rat pancreas after chronic alcohol exposure: the role of peroxisome proliferator-activated receptor gamma.
Immunoenzymometric determination of trypsin/alpha 1-protease inhibitor complex in plasma of rats with experimental pancreatitis.
Immunohistochemical localization of trypsinogen and trypsin in acute and chronic pancreatitis.
Immunoreactive forms of cationic trypsin in plasma and ascitic fluid of dogs in experimental pancreatitis.
Immunoreactive serum trypsin in diseases of the pancreas.
Immunoreactive trypsin in acute pancreatitis: elevated levels do not correlate with hyperamylasaemia.
Immunoreactive trypsin in serum and peritoneal fluid in acute pancreatitis.
Immunoreactive trypsins in sera from dogs before and after induction of experimental pancreatitis.
Impact of microcirculatory flow pattern changes on the development of acute edematous and necrotizing pancreatitis in rabbit pancreas.
Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis.
Impaired autophagy and organellar dysfunction in pancreatitis.
Impaired mononuclear phagocyte function in patients with severe acute pancreatitis: evidence from studies of plasma clearance of trypsin and monocyte phagocytosis.
Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis.
In acute pancreatitis the decrease of villous activity, the damage of the intestinal mucosa might be induced by agents produced during pancreatitis or by trypsin.
In vivo activation of gelatinase B/MMP-9 by trypsin in acute pancreatitis is a permissive factor in streptozotocin-induced diabetes.
Inactivation of mesotrypsin by chymotrypsin C prevents trypsin inhibitor degradation.
Increased activation of hereditary pancreatitis-associated human cationic trypsinogen mutants in presence of chymotrypsin C.
Increased lung vascular permeability after pancreatitis and trypsin infusion.
Increased serum trypsin and elastase-1 levels in patients undergoing L-asparaginase therapy.
Increased serum trypsinogen 2 and trypsin 2-1 antitrypsin complex values identify endoscopic retrograde cholangiopancreatography (ERCP)-induced pancreatitis with high accuracy.
Increased serum trypsinogen 2 and trypsin 2-alpha 1 antitrypsin complex values identify endoscopic retrograde cholangiopancreatography induced pancreatitis with high accuracy.
Influence of hormonal stimulation by caerulein on acute experimental pancreatitis in the rat.
Influence of intraluminal trypsin activity on the course of acute experimental pancreatitis.
Influence of the human pancreatic secretory trypsin inhibitor on trypsin-induced C3 and kininogen cleavage: an in vitro study.
Influence of trypsin-induced acute pancreatitis on survival and energy state of isolated acinar cells from rat pancreas.
Inhibition of cathepsin B does not affect the intracellular activation of trypsinogen by cerulein hyperstimulation in isolated rat pancreatic acinar cells.
Inhibition of cyclooxygenase-2 ameliorates the severity of pancreatitis and associated lung injury.
Inhibition of human pancreatic proteinases by human plasma alpha2-antiplasmin and antithrombin.
Inhibition of inducible nitric oxide synthase reduces bacterial translocation in a rat model of acute pancreatitis.
Inhibitory effect of human urinary trypsin inhibitor (urinastatin) on lysosomal thiol proteinases.
Inhibitory effects of daidzein and genistein on trypsin: Insights from spectroscopic and molecular docking studies.
Interaction between trypsinogen isoforms in genetically determined pancreatitis: mutation E79K in cationic trypsin (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2).
Intra-acinar cell activation of trypsinogen during caerulein-induced pancreatitis in rats.
Intracellular trypsin induces pancreatic acinar cell death but not NF-{kappa}B activation.
Intragenic duplication: a novel mutational mechanism in hereditary pancreatitis.
Intrapancreatic turnover of recombinant human pancreatic secretory trypsin inhibitor in experimental porcine pancreatitis.
Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells.
Involvement of tubular complexes in pancreatic regeneration after acute necrohemorrhagic pancreatitis.
K+-induced ion-exchanges trigger trypsin activation in pancreas acinar zymogen granules.
Keratin 8 Mutations Are Not Associated with Familial, Sporadic and Alcoholic Pancreatitis in a Population from the United States.
Ketamine and xylazine effects in murine model of acute pancreatitis.
Kininogen level in clinical pancreatitis during treatment with trypsin inhibitor from bovine lung.
Label-free nanopore single-molecule measurement of trypsin activity.
Laboratory tests in the differential diagnosis of hyperamylasemia.
Lack of R117H mutation in the cationic trypsinogen gene in patients with tropical pancreatitis from Bangladesh.
Lack of significant association of an insertion/deletion polymorphism in the angiotensin converting enzyme (ACE) gene with tropical calcific pancreatitis.
Lessons from hereditary pancreatitis.
Local administration of human pancreatic secretory trypsin inhibitor prevents the development of experimental acute pancreatitis in rats and dogs.
Local clustering of PRSS1 R122H mutations in hereditary pancreatitis patients from Northern Germany.
Localized necrohemorrhagic pancreatitis in the rat after pancreatic interstitial trypsin injection. Regressive pseudochronic lesions.
Long-term ethanol consumption alters pancreatic gene expression in rats: a possible connection to pancreatic injury.
Loss of chymotrypsin-like protease (CTRL) alters intrapancreatic protease activation but not pancreatitis severity in mice.
Low-volume continuous hemodiafiltration with nafamostat mesilate increases trypsin clearance without decreasing plasma trypsin concentration in severe acute pancreatitis.
Lymphotoxin ? Receptor Signaling Promotes Development of Autoimmune Pancreatitis.
Macrolipasemia in Crohn's disease.
Matrix metalloproteinase-9 promotes neutrophil migration and alveolar capillary leakage in pancreatitis-associated lung injury in the rat.
Measuring digestive protease activation in the mouse pancreas.
Mechanism of acute pancreatitis exacerbation by enteral bile-pancreatic juice exclusion.
Mechanisms of acute pancreatitis. Vascular etiology.
Mechanisms of intracellular zymogen activation.
Melatonin attenuates the in?ammatory response via inhibiting the C/EBP homologous protein-mediated pathway in taurocholate-induced acute pancreatitis.
Membrane-bound ICAM-1 is upregulated by trypsin and contributes to leukocyte migration in acute pancreatitis.
Microcirculation of the normal and inflamed canine pancreas.
Misfolding cationic trypsinogen variant p.L104P causes hereditary pancreatitis.
Modification of the muscular contractility of the vena porta in trypsinemia.
Molecular advances in pancreatic cancer.
Molecular basis of hereditary pancreatitis.
Molecular forms of immunoreactive pancreatic cationic trypsin in pancreatitis patient sera.
Molecular pathology and evolutionary and physiological implications of pancreatitis-associated cationic trypsinogen mutations.
Molecular understanding of chronic pancreatitis: a perspective on the future.
Monitoring serum tryptic activity and effect of trypsin inhibitor on rat acute pancreatitis.
Mouse model suggests limited role for human mesotrypsin in pancreatitis.
Multifactorial Genesis of Pancreatitis in Primary Hyperparathyroidism: Evidence for "Protective" (PRSS2) and "Destructive" (CTRC) Genetic Factors.
Multisite mutations of the PRSS1 gene in a Chinese patient with chronic pancreatitis.
Mutation analysis of the cationic trypsinogen gene in patients with pancreatic cancer.
Mutation analysis of the cystic fibrosis and cationic trypsinogen genes in patients with alcohol-related pancreatitis.
Mutation That Promotes Activation of Trypsinogen Increases Severity of Secretagogue-Induced Pancreatitis in Mice.
Mutational analysis of the pancreatic secretory trypsin inhibitor gene in familial and juvenile pancreatitis in Japan.
Mutational screening of the cationic trypsinogen gene in a large cohort of subjects with idiopathic chronic pancreatitis.
Mutations in anionic trypsinogen gene are not associated with tropical calcific pancreatitis.
Mutations in exons 2 and 3 of the cationic trypsinogen gene in Japanese families with hereditary pancreatitis.
Mutations in serine protease inhibitor Kazal type 1 are strongly associated with chronic pancreatitis.
Mutations in the cationic trypsinogen gene and evidence for genetic heterogeneity in hereditary pancreatitis.
Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis.
Mutations in the pancreatic secretory trypsin inhibitor gene (PSTI/SPINK1) rather than the cationic trypsinogen gene (PRSS1) are significantly associated with tropical calcific pancreatitis.
Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis.
Mutations of the cationic trypsinogen gene in hereditary and non-hereditary pancreatitis.
Mutations of the cationic trypsinogen gene in patients with chronic pancreatitis.
Mutations of the cationic trypsinogen gene in patients with hereditary pancreatitis.
Mutations of the cationic trypsinogen in hereditary pancreatitis.
Mutations of the cystic fibrosis gene, but not cationic trypsinogen gene, are associated with recurrent or chronic idiopathic pancreatitis.
Natural single-nucleotide deletion in chymotrypsinogen C gene increases severity of secretagogue-induced pancreatitis in C57BL/6 mice.
Neurogenic inflammation and pancreatitis.
Neutrophil Extracellular Traps Induce Trypsin Activation, Inflammation, and Tissue Damage in Mice With Severe Acute Pancreatitis.
Neutrophils and NADPH oxidase mediate intrapancreatic trypsin activation in murine experimental acute pancreatitis.
New horizons in pancreatic genetics.
Novel cationic trypsinogen (PRSS1) N29T and R122C mutations cause autosomal dominant hereditary pancreatitis.
Novel mutation and polymorphism of PRSS1 gene in the Chinese patients with hereditary pancreatitis and chronic pancreatitis.
Novel Pathogenic PRSS1 Variant p.Glu190Lys in a Case of Chronic Pancreatitis.
On the potential role of trypsin and trypsin inhibitors in acute pancreatitis.
On the role of the pancreatic secretory trypsin inhibitor as an inactivator of trypsin-alpha 2-macroglobulin complexes in acute pancreatitis.
Origin and implication of the hereditary pancreatitis-associated N21I mutation in the cationic trypsinogen gene.
Overexpression of heat shock protein Hsp27 protects against cerulein-induced pancreatitis.
Overexpression of Smad6 Exacerbates Pancreatic Fibrosis in Murine Caerulein-Induced Chronic Pancreatic Injuries.
Paediatric and hereditary aspects of chronic pancreatitis.
Pancreas-specific SNAP23 depletion prevents pancreatitis by attenuating pathological basolateral exocytosis and formation of trypsin-activating autolysosomes.
Pancreatic acinar cell function and morphology in rats chronically fed an ethanol diet.
Pancreatic cationic elastase in porcine experimental pancreatitis.
Pancreatic proteases in serum induce leukocyte-endothelial adhesion and pancreatic microcirculatory failure.
Pancreatic secretory proteins in sera from rats before and after induction of experimental pancreatitis.
Pancreatic secretory trypsin inhibitor (SPINK1) gene mutations in patients with acute pancreatitis.
Pancreatic secretory trypsin inhibitor causes autocrine-mediated migration and invasion in bladder cancer and phosphorylates the EGF receptor, Akt2 and Akt3, and ERK1 and ERK2.
Pancreatic secretory trypsin inhibitor I reduces the severity of chronic pancreatitis in mice overexpressing interleukin-1? in the pancreas.
Pancreatitis in childhood.
Pancreatitis in fibrocalculous pancreatic diabetes mellitus is not associated with common mutations in the trypsinogen gene.
Pancreatitis risk in primary hyperparathyroidism: relation to mutations in the SPINK1 trypsin inhibitor (N34S) and the cystic fibrosis gene.
Pancreatitis-induced increase in lung vascular permeability. Protective effect of Trasylol.
PAR2 exerts local protection against acute pancreatitis via modulation of MAP kinase and MAP kinase phosphatase signaling.
Parenteral administration of trypsin triggers lung emphysema.
Pathogenic cellular role of the p.L104P human cationic trypsinogen variant in chronic pancreatitis.
Pathogenic mechanisms of pancreatitis.
Pathomorphological analysis of the pancreaticoduodenal organs in experimental pancreonecrosis induced by trypsin injection.
Pathophysiology of acute and infected pancreatitis.
Pathophysiology of alcohol-induced pancreatitis.
Pathophysiology of SPINK mutations in pancreatic development and disease.
Peritoneal absorption of pancreatic enzymes in bile-induced acute pancreatitis in dogs.
Peritoneal lavage efficiently eliminates protease-alpha-2-macroglobulin complexes and components of the contact system from the peritoneal cavity in patients with severe acute pancreatitis.
Peritoneal lavage with aprotinin in patients with severe acute pancreatitis. Effects on plasma and peritoneal levels of trypsin and leukocyte proteases and their major inhibitors.
Phosphatidylinositol 3-kinase and trypsin activation in pancreatitis.
Plasma beta-endorphin and the effect of naloxone on hemodynamic changes during experimental acute pancreatitis in dogs.
Plasma levels of elastase, trypsin and their inhibitors in bile induced pancreatitis in the dog.
Polyamine catabolism in relation to trypsin activation and apoptosis in experimental acute pancreatitis.
Premature trypsin activation in hereditary pancreatitis.
Presence of cathepsin B in the human pancreatic secretory pathway and its role in trypsinogen activation during hereditary pancreatitis.
Prevention of acute experimental pancreatitis in rats and dogs by intraduodenal infusion of a synthetic trypsin inhibitor.
Prevention of experimental acute pancreatitis by intraduodenal trypsin inhibitor in rat.
Preventive effects of ulinastatin on complications related to pancreaticoduodenectomy: A Consort-prospective, randomized, double-blind, placebo-controlled trial.
Proinflammatory role of trypsin and protease-activated receptor-2 in a rat model of acute pancreatitis.
Prostacyclin (PGI2) stabilises hepatic lysosomes during acute experimental pancreatitis in dogs.
Prostacyclin and thromboxane in acute hemorrhagic pancreatitis in dogs.
Prostaglandin F2 alpha and prostacyclin tissue levels in early phases of trypsin-induced acute pancreatitis in rats.
Protease activation during in vivo pancreatitis is dependent on calcineurin activation.
Protease Activation during in vivo Pancreatitis is Dependent upon Calcineurin Activation.
Protease-activated receptor 2 exerts local protection and mediates some systemic complications in acute pancreatitis.
Protease-activated receptor-2 protects against pancreatitis by stimulating exocrine secretion.
Protease-activated receptor-2-mediated proliferation and collagen production of rat pancreatic stellate cells.
Protease-Sensitive Pancreatic Lipase Variants Are Associated With Early Onset Chronic Pancreatitis.
Protection against acute pancreatitis by activation of protease-activated receptor-2.
Protection from pancreatitis by the zymogen granule membrane protein integral membrane-associated protein-1.
Protective effect of a pancreatic elastase inhibitor against a variety of acute pancreatitis in rats.
Protective effect of human pancreatic secretory trypsin inhibitor on cerulein-induced acute pancreatitis in rats.
Protective effect of the combined treatment of pancreatic and neutrophil elastase inhibitors on acute pancreatitis elicited by lipopolysaccharide in rats given intraductal injection of taurocholate plus trypsin.
Protective effects of urinary trypsin inhibitor on systemic inflammatory response induced by lipopolysaccharide.
Protective role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide.
Protective role of urinary trypsin inhibitor in lung expression of proinflammatory cytokines accompanied by lethal liver injury in mice.
Proteomic analysis of pancreatic secretory trypsin inhibitor/tumor-associated trypsin inhibitor from urine of patients with pancreatitis or prostate cancer.
PRSS1 and SPINK1 mutations in idiopathic chronic and recurrent acute pancreatitis.
Pulmonary surface tension after nontoxic experimental pancreatitis.
Pulmonary vascular injury in pancreatitis: evidence for a major role played by pancreatic elastase.
Purification and some properties of a low molecular weight trypsin inhibitor from acute pancreatitis urine.
R116C mutation of cationic trypsinogen in a Turkish family with recurrent pancreatitis illustrates genetic microheterogeneity of hereditary pancreatitis.
Radioimmunoassay of cationic trypsin-like immunoreactivity in man.
Radioimmunoreactive serum elastase levels and histologic changes during experimental pancreatitis in rats.
Randomized clinical trial to assess the efficacy of ulinastatin for postoperative pancreatitis following pancreaticoduodenectomy.
Recent advances in studies of molecular hydrogen in the treatment of pancreatitis.
Relation of alpha 2-macroglobulin and other antiproteases to the clinical features of acute pancreatitis.
Relationship between enteric microecologic dysbiosis and bacterial translocation in acute necrotizing pancreatitis.
Release of Cathepsin B in Cytosol Causes Cell Death in Acute Pancreatitis.
Removal of trypsin complexed alpha-2 macroglobulin by plasma fractionation.
Renal microcirculation in experimental acute pancreatitis of dogs.
Retardation of the progress of experimental pancreatitis with trypsin inhibitors.
Rhubarb combined with trypsin inhibitor for severe acute pancreatitis: A systematic review and meta-analysis.
Robust autoactivation, chymotrypsin C independence and diminished secretion define a subset of hereditary pancreatitis-associated cationic trypsinogen mutants.
Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis.
Role of Intrapancreatic SPINK1/Spink3 Expression in the Development of Pancreatitis.
Role of macrophage migration inhibitory factor in acute lung injury in mice with acute pancreatitis complicated by endotoxemia.
Role of oxygen-derived free radicals in protease activation after pancreas transplantation in the pig.
Role of reactive oxygen metabolites in early cardiopulmonary changes of acute hemorrhagic pancreatitis.
Role of the kallikrein-kinin system in human pancreatitis.
Role of Ulinastatin, a trypsin inhibitor, in severe acute pancreatitis in critical care setting: A retrospective analysis.
Roles of Autophagy and Pancreatic Secretory Trypsin Inhibitor in Trypsinogen Activation in Acute Pancreatitis.
Salidroside alleviates taurolithocholic acid 3-sulfate-induced AR42J cell injury.
Screening for human cationic trypsinogen (PRSS1) and trypsinogen inhibitor gene (SPINK1) mutations in a Finnish family with hereditary pancreatitis.
Screening for mutations of the cationic trypsinogen gene: are they of relevance in chronic alcoholic pancreatitis?
Selected biochemical parameters and ultrastructural picture of pancreas due to Ulinastatin treatment of experimental acute pancreatitis.
Selectively aspirated pure pancreatic secretion. Viscosity, trypsin activity, protein concentration and lactoferrin content of pancreatic juice in chronic pancreatitis.
Self-powered sensor for naked-eye detection of serum trypsin.
Sequential connective matrix changes in experimental acute pancreatitis. An immunohistochemical and biochemical assessment in the rat.
Serial alterations in the forms of immunoreactive pancreatic cationic trypsin in plasma from patients with acute pancreatitis.
Serine protease inhibitor Kazal type 1 mutations and pancreatitis.
Serine protease inhibitor kazal type 1 mutations and pancreatitis.
Serine Proteases Mediate Inflammatory Pain in Acute Pancreatitis.
Serum complex of trypsin 2 and alpha 1 antitrypsin as diagnostic and prognostic marker of acute pancreatitis: clinical study in consecutive patients.
Serum immunoreactive trypsin and trypsin inhibitors during acute pancreatitis.
Serum pancreatic secretory trypsin inhibitor in acute pancreatitis.
Serum phospholipase A2, immunoreactive trypsin, and trypsin inhibitors during human acute pancreatitis.
Serum Serine Peptidase Inhibitor Kazal-Type 1, Trypsinogens 1 to 3, and Complex of Trypsin 2 and ?1-Antitrypsin in the Diagnosis of Severe Acute Pancreatitis.
Serum tests for pancreatitis in patients with abdominal pain.
Serum trypsin and TCR as novel markers for predicting disease activity in IgG4-related disease.
Serum trypsin levels in acute pancreatic and non-pancreatic abdominal conditions.
Signal peptide variants that impair secretion of pancreatic secretory trypsin inhibitor (SPINK1) cause autosomal dominant hereditary pancreatitis.
Site-specific therapeutic effects of protease inhibitors: effect of route of administration in experimental pancreatitis.
Soybean trypsin inhibitor and cerulein accelerate recovery of cerulein-induced pancreatitis in rats.
Specific immunoassay reveals increased serum trypsinogen 3 in acute pancreatitis.
Sphincter of Oddi function studied by radioimmunoassay of biliary trypsin in patients with bile duct stones and in controls.
SPINK1/PSTI mutations are associated with tropical pancreatitis in Bangladesh. A preliminary report.
SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis.
Stress kinase inhibition modulates acute experimental pancreatitis.
Strong evidence that the N21I substitution in the cationic trypsinogen gene causes disease in hereditary pancreatitis.
Studies of pure pancreatic secretions in chronic alcoholic subjects without pancreatic insufficiency.
Studies on serum amylase in normal man and in acute pancreatitis.
Studies on the ascites fluid of acute pancreatitis in man.
Studies on the kallikrein-kinin system in plasma and peritoneal fluid during experimental pancreatitis.
Studies on the turnover of endogenous cathodal trypsinogen in man.
Sudden blindness in acute pancreatitis. Possible role of complement-induced retinal leukoembolization.
Survival and morphology of isolated pancreatic acinar cells from rats with induced acute pancreatitis are not improved with anti-inflammatory drugs.
Synthetic antiproteases in acute pancreatitis: an experimental study.
Systematic review and meta-analysis of the efficacy of trypsin inhibitors in patients with severe pancreatitis.
Systolic time intervals in canine experimental acute hemorrhagic pancreatitis.
Tauroursodeoxycholic acid reduces endoplasmic reticulum stress, acinar cell damage, and systemic inflammation in acute pancreatitis.
Temporary pseudochronic lesions during the recovery of acute necrohemorrhagic pancreatitis in rabbits.
The cholecystokinin receptor antagonist L-364,718 reduces taurocholate-induced pancreatitis in rats.
The Complex Role of Trypsin in Pancreatitis.
The course of genetically determined chronic pancreatitis.
THE EFFECT OF A TRYPSIN INHIBITOR, TRASYLOL, ON THE COURSE OF BILE AND TRYPSIN-INDUCED PANCREATITIS IN DOGS.
The effect of ERCP on circulating pancreatic enzymes and pancreatic protease inhibitors.
The effect of interleukin-6 on bacterial translocation in acute canine pancreatitis.
The effect of peritoneal dialysis with and without aprotinin on acute experimental pancreatitis in rats.
The effect of phenylbutazone on acute hemorrhagic pancreatitis in the rat.
The effects of a thromboxane A2 synthesis inhibitor and a prostaglandin I2 analogue on experimental acute necrotizing pancreatitis in rats.
The effects upon blood coagulation in dogs of experimentally induced pancreatitis and the infusion of pancreatic juice.
The elimination of trypsin--alpha-macroglobulin complexes from the blood circulation in pigs during acute pancreatitis and after massive intravenous trypsin infusion.
The Guinea pig pancreas secretes a single trypsinogen isoform, which is defective in autoactivation.
The influence of caecostomy and colonic irrigation on pathophysiology and prognosis in acute experimental pancreatitis.
The Orai Ca2+ channel inhibitor CM4620 targets both parenchymal and immune cells to reduce inflammation in experimental acute pancreatitis.
The p.E152K-STIM1 mutation deregulates Ca2+ signaling contributing to chronic pancreatitis.
The pancreatitis-associated protein in hereditary and chronic alcoholic pancreatitis.
The pathobiochemistry of hereditary pancreatitis: studies on recombinant human cationic trypsinogen.
The Prevalence and Characteristics of Genetic Pancreatitis in Children with Chronic and Recurrent Acute Pancreatitis.
The protective effect of the trypsin inhibitor urinastatin on cerulein-induced acute pancreatitis in rats.
The protective effects of long-acting recombinant human pancreatic secretory trypsin inhibitor (R44S-PSTI) in a rat model of cerulein-induced pancreatitis.
The proteinases and proteinase inhibitors in the peritoneal exudate during acute experimental pancreatitis in the rat.
The proteome of mesenteric lymph during acute pancreatitis and implications for treatment.
The Relationship between Trypsin/Calcitonin Gene Related Peptide (CGRP) in Serum and Acute Pancreatitis (AP).
The relative values of serum immuno-reactive trypsin concentration and total amylase activity in the diagnosis of mumps, chronic renal failure, and pancreatic disease.
The role of calcium in pancreatitis.
The role of calcium-binding protein S100g (CalbindinD-9K) and annexin A10 in acute pancreatitis.
THE ROLE OF PANCREATIC ENZYMES IN THE PATHOGENESIS OF ACUTE PANCREATITIS. III.COMPARISON OF THE PATHOLOGIC AND BIOCHEMICAL CHANGES IN THE CANINE PANCREAS TO INTRADUCTAL INJECTION WITH BILE AND WITH TRYPSIN.
The role of pancreatic enzymes in the pathogenesis of acute pancreatitis. The failure of a trypsin inhibitor: benzethonium chloride to prevent experimental acute pancreatitis.
The role of serum trypsin inhibitors in acute pancreatitis.
The role of trypsin and of bile salts in the pathogenesis of acute pancreatitis.
The role of trypsin, trypsin inhibitor, and trypsin receptor in the onset and aggravation of pancreatitis.
The significance of reflux of trypsin and bile in the pathogenesis of human pancreatitis.
The soymilk diet: A previously unknown etiology of acute pancreatitis.
The spectrum of complications of hereditary pancreatitis. Is this a model for future gene therapy?
The SPINK1 N34S variant is associated with acute pancreatitis.
The therapeutic effect of a new synthetic protease inhibitor (E-3123) on hemodynamic changes during experimental acute pancreatitis in dogs.
The treatment of chronic recurrent pancreatitis with depot secretin--a preliminary report.
The variable phenotype of the p.A16V mutation of cationic trypsinogen (PRSS1) in pancreatitis families.
The vasoactive properties of ascitic fluid in acute pancreatitis in a porcine model.
Therapeutic efficacy of an antineutrophil monoclonal antibody, Urge-8, against acute necrotizing pancreatitis in rats.
Tighter Control by Chymotrypsin C (CTRC) Explains Lack of Association between Human Anionic Trypsinogen and Hereditary Pancreatitis.
Toxic products in hemorrhagic ascitic fluid generated during experimental acute hemorrhagic pancreatitis in dogs and a treatment which reduces their effect.
Transforming growth factor-beta1, interleukin-10 and interferon-gamma cytokine polymorphisms in patients with hereditary, familial and sporadic chronic pancreatitis.
Transgenic expression of pancreatic secretory trypsin inhibitor-I ameliorates secretagogue-induced pancreatitis in mice.
Tropical calcific pancreatitis: strong association with SPINK1 trypsin inhibitor mutations.
Trypsin activation peptide (TAP) in acute pancreatitis: from pathophysiology to clinical usefulness.
Trypsin activity governs increased susceptibility to pancreatitis in mice expressing human PRSS1R122H.
Trypsin activity. A new marker of acute alcoholic pancreatitis.
Trypsin and activation of circulating trypsinogen contribute to pancreatitis-associated lung injury.
Trypsin and splanchnic protein turnover during feeding and fasting in human subjects.
Trypsin Detection Strategies: A Review.
Trypsin encoding PRSS1-PRSS2 variation influence the risk of asparaginase-associated pancreatitis in children with acute lymphoblastic leukemia: a Ponte di Legno toxicity working group report.
Trypsin inhibitor and proteolytic enzyme activity in dogs after ethionine-induced pancreatitis.
Trypsin inhibitor levels in experimental pancreatitis.
TRYPSIN INHIBITOR PARTITION IN PANCREATITIS.
Trypsin inhibitors for the treatment of pancreatitis.
Trypsin is the culprit of multiple organ injury with severe acute pancreatitis.
TRYPSIN RELEASE, KININ PRODUCTION, AND SHOCK; RELATIONSHIP IN EXPERIMENTAL AND HUMAN PANCREATITIS.
Trypsin secretion and turnover in patients with acute pancreatitis.
Trypsin(ogen) content of pancreatic calculi in chronic calcified pancreatitis in man.
Trypsin-based laboratory methods and carboxypeptidase activation peptide in acute pancreatitis.
Trypsin-like activity and thromboxane release in adult respiratory distress syndrome.
Trypsin-like immunoreactivity in the diagnosis of acute pancreatitis.
Trypsinogen gene mutations in patients with chronic or recurrent acute pancreatitis.
Trypsinogen stabilization by mutation Arg117-->His: a unifying pathomechanism for hereditary pancreatitis?
Tumour-associated trypsin inhibitor, TATI, in patients with pancreatic cancer, pancreatitis and benign biliary diseases.
Two novel severe mutations in the pancreatic secretory trypsin inhibitor gene (SPINK1) cause familial and/or hereditary pancreatitis.
Ulinastatin ameliorates tissue damage of severe acute pancreatitis through modulating regulatory T cells.
Ulinastatin Exerts Synergistic Effects with Taxotere and Inhibits Invasion and Metastasis of Breast Cancer by Blocking Angiogenesis and the Epithelial-Mesenchymal Transition.
Ulinastatin suppresses lipopolysaccharide-induced prostaglandin E2 synthesis and nitric oxide production through the downregulation of nuclear factor??B in BV2 mouse microglial cells.
Ultrastructural studies of experimental acute pancreatitis.
Uncertainties in the classification of human cationic trypsinogen (PRSS1) variants as hereditary pancreatitis-associated mutations.
Urinary enzymes excretion in pancreatic diseases. Clinical role and pathophysiological considerations.
Urinary immunoreactive trypsin excretion: a non-invasive screening test for pancreatic cancer.
Urinary trypsin inhibitor as a therapeutic option for endotoxin-related inflammatory disorders.
Urinary trypsin inhibitor attenuates liver enzyme elevation after liver resection.
Urinary trypsin inhibitor protects against liver injury and coagulation pathway dysregulation induced by lipopolysaccharide/D-galactosamine in mice.
Urinary trypsin inhibitor protects against systemic inflammation induced by lipopolysaccharide.
Urinary trypsin inhibitor reduces inflammatory response in kidney induced by lipopolysaccharide.
Urinary trypsin inhibitor suppresses surgical stress-facilitated lung metastasis of murine colon 26-L5 carcinoma cells.
Usefulness of carbohydrate-deficient transferrin and trypsin activity in the diagnosis of acute alcoholic pancreatitis.
Usefulness of determination of serum immunoreactive pancreatic phospholipase A2 content for early identification of severe acute pancreatitis.
Variants in CPA1 are strongly associated with early onset chronic pancreatitis.
Xylocaine treatment in experimental pancreatitis in pigs.
[3 cases of acute pancreatitis treated by inhibition of trypsin.]
[A case of R122H mutation of cationic trypsinogen gene in a pediatric patient with hereditary pancreatitis complicated by pseudocyst and hemosuccus pancreaticus]
[Absorption of trypsin and its inhibitors from the abdominal cavity in experimental acute pancreatitis]
[ACUTE PANCREATITIS AND ITS TREATMENT WITH A TRYPSIN INACTIVATOR.]
[Acute pancreatitis and the lung--a comparative study with lung lesions induced by trypsin infusion]
[Acute pancreatitis induced by bile trypsin: structural and ultrastructural study]
[Acute pancreatitis: trypsin activators and inhibitors.]
[An electron microscopical study on the pathogenesis of taurocholate-induced acute pancreatitis]
[An experimental study on curative effect of Chinese medicine qing yi tang in acute necrotizing pancreatitis]
[Analysis by means of pancreatozymin of the degree of parallelism of secretion of pancreatic enzymes in healthy persons and patients with chronic pancreatitis]
[APROPOS OF THE TREATMENT OF PANCREATITIS WITH TRYPSIN INHIBITORS. CRITICAL REMARKS.]
[APROPOS OF TRYPSIN INACTIVATION IN THE TREATMENT OF ACUTE PANCREATITIS.]
[Cationic trypsinogen gene mutation in patients with chronic idiopathic pancreatitis]
[Change in proteolytic enzymatic activity in the blood serum in children with chronic diseases of the digestive organs]
[Changes in blood enzyme activity and tumor necrosis factor level in the treatment of experimental pancreatitis with pentoxifylline]
[Changes in serum pancreatic enzymes and pancreatic secretory trypsin inhibitor in patients with severe acute pancreatitis]
[Clinical implications of genetic risk factors of chronic pancreatitis]
[Dalargin in the prevention of acute postoperative pancreatitis]
[Defense mechanism to prevent ectopic activation of pancreatic digestive enzymes under physiological conditions and its breakdown in acute pancreatitis]
[Diagnostic usefulness and prognostic value of inhibitory capacity and other biochemical parameters of plasma in acute pancreatitis in humans]
[Diagnostic value of serum pancreatic secretory trypsin inhibitor (PSTI) in acute pancreatitis]
[Effect of 5-fluorouracil on the enzymatic activity of the pancreas and blood serum of rats with acute pancreatitis]
[Effect of protease inhibitors on the activity of trypsin and lipase in the pancreas and blood serum of rats in acute pancreatitis]
[Effect of trypsin and kallikrein (andecalin) on the activity of proteolytic enzymes and their inhibitors in acute experimental pancreatitis]
[Effects of bovine pancreatic polypeptide on phospholipase A and trypsin activities in pancreatic tissue in rats with acute pancreatitis]
[Effects of E-3123, a new protease inhibitor, on several protease activities and on experimental acute pancreatitis]
[Effects of several regulatory peptides on the functional activity of the pancreas in acute experimental pancreatitis]
[Effects of trypsin and kallikrein inhibition in acute pancreatitis]
[Evaluation of measuring serum trypsin by radioimmunoassay and clinical application for the study on the exocrine function in diabetics (author's transl)]
[Examination of pancreatic function in children with special reference to the PABA-test (author's transl)]
[Experimental acute pancreatitis in rats and its histopathologic evolution in time. 3. Acute pancreatitis induced with trypsin inhibitors: zymofren and iniprol]
[Experimental acute pancreatitis in rats and its histopathologic evolution in time. II. Acute pancreatitis induced with different enzymes: trypsin, alphachymotrypsin, elastase, collagenase and lipase]
[Experimental studies of the role of trypsin in acute pancreatitis.]
[Experimental studies on the significance of the measurement of serum pancreatic secretory trypsin inhibitor in acute pancreatitis]
[Experimental trypsin pancreatitis in indirect and direct cooling of organs]
[Genetic aspects of digestive diseases. Part 1]
[Genetic risk factors in pancreatic diseases--significance for general practice]
[Hemodynamic and microcirculatory changes in the liver in experimental acute pancreatitis of dogs]
[Hemostatic function and level of autoantibodies to trypsin and factor Xa in rats in experimental pancreatitis]
[Hereditary pancreatitis - a clinically relevant cause of pancreatic adenocarcinoma?]
[Hereditary pancreatitis caused by a new mutation in the trypsinogen gene. Report of a family]
[Hereditary pancreatitis is due to a mutation of the cationic trypsinogen gene]
[Hereditary pancreatitis]
[Hydrolysis by enteropeptidase of nonspecific (model) peptide sequences and possible physiological role of this phenomenon]
[Identical Variants Different Disease Course - Genetics of Chronic Pancreatitis].
[Immunoreactive trypsin in the serum of normal children and children with gastrointestinal diseases]
[IN VITRO AND IN VIVO STUDY OF A TRYPSIN INHIBITOR IN ACUTE PANCREATITIS: EXPERIMENTAL STUDY AND A REPORT OF ITS USE IN HUMAN CASE.]
[Increasing of the trypsin rate frequency in the blood serum in children with viral hepatitis].
[Inhibition of the secretion of endogenous insulin and trypsin by exogenous insulin and trypsin in the complex treatment of acute pancreatitis]
[Interaction of proteases and their inhibitors in the pathogenesis of pancreatitis]
[Laboratory diagnosis of pancreatitis and pancreatic cancer]
[Light microscopy and autoradiography studies of the organization of trypsin pancreatitis]
[Method of determining trypsin and trypsinogen in a homogenate of animal pancreas in experimental pancreatitis]
[Modification of the method of trypsin esterase activity determination]
[Mutations of the pancreatic secretory trypsin inhibitor. Is the cause of chronic pancreatitis now known?]
[On the possibility of causal modification of acute pancreatitis by inactivation of trypsin.]
[PANCREATIC JUICE SECRETION AND BEHAVIOR OF TRYPSIN IN EXPERIMENTAL ACUTE PANCREATITIS.]
[Pancreatic microcirculation in acute pancreatitis of dogs]
[Pancreatitis--etiology and pathogenesis]
[Pancreatitis-associated gene mutations]
[Pharmacological studies of FUT-175, nafamstat mesilate. II. Effects on experimental acute pancreatitis]
[Possibilities of determination of trypsin in the blood serum of patients with pancreatitis]
[Radioimmunoassay in the evaluation of pancreas function in chronic pancreatitis]
[Regulation and self-regulation of the pancreas secretion]
[Renal microcirculation in experimental acute pancreatitis of dogs--the effect of pancreatic protease inhibitor and dopamine]
[Significance of immunoreactive lipase in the diagnosis of pancreatic diseases]
[Significance of trypsinogen gene mutations in the etiology of hereditary pancreatitis]
[Starting mechanisms of trypsinogen activation in acute pancreatitis]
[STUDIES ON THE EFFECTS OF A TRYPSIN INHIBITOR (TRASYLOL) ON ENZYME ACTIVITIES AND MORPHOLOGY IN TAUROCHOLATE AND CALCIPHYLAXIS PANCREATITIS OF THE RAT (A CONTRIBUTION TO THE PATHOGENESIS OF PANCREATITIS. II.)]
[Study of an optimal biological profile for demonstrating pancreatic involvement in acute abdominal syndrome]
[The diagnostic significance of pancreatic enzymes in the blood serum and urine in chronic pancreatitis]
[The diagnostic significance of soluble fibrin monomer complexes in exacerbated chronic recurrent pancreatitis]
[The efficacy of the combined use of 5-fluorouracil electrophoresis and magnetotherapy in experimental pancreatitis]
[The Pancreas Study Group: Inhibition of pancreas secretion and trypsin activity. Mechanisms and importance of therapy of acute and chronic pancreatitis]
[The pathogenesis of infection complicated by acute necrotizing pancreatitis: an experimental study]
[The role of amylase in abdominal fluid in evaluating severity of acute pancreatitis and its prognosis]
[The role of trypsin in acute pancreatitis.]
[The serum enzymogram for the evaluation of the effectiveness of hemosorption in patients with acute destructive pancreatitis]
[The significance of trypsin, amylase and lipase activities in the blood serum for the differential,diagnosis of chronic pancreatitis and other diseases of the abdominal organs]
[The treatment of acute pancreatitis by blocking the pancreatic secretion with trypsin inactivators]
[The value of estimation of serum pancreatic elastase in experimental pancreatic disorders in rats]
[Therapeutic action mechanism of trypsin inhibitors in acute pancreatitis]
[Therapeutic effects of human urinary trypsin inhibitor on acute experimental pancreatitis]
[Therapy with kallikrein and trypsin inhibitors, a part of the modern treatment of acute pancreatitis.]
[Three cases of hereditary pancreatitis in two households in the same family associated with R122H mutation in cationic trypsinogen gene]
[TREATMENT OF PANCREATITIS WITH TRYPSIN INHIBITORS. REPORT OF 4 CASES.]
[Trypsin and trypsin inhibitor level in the blood serum in various forms of acute pancreatitis]
[Trypsin dosage in acute pancreatitis]
[Trypsin in the blood in pancreatitis: facts, assumptions, errors]
Pancreatitis, Acute Hemorrhagic
Amelioration of pancreatitis with azathioprine.
Aprotinin and Na2CaEDTA in experimental hemorrhagic pancreatitis in pigs.
Effect of a new inhibitor of type II phospholipase A2 on experimental acute pancreatitis in rats.
Effect of a specific synthetic inhibitor of neutrophil elastase (ONO-5046) on the course of acute hemorrhagic pancreatitis in dogs.
Effect of protease inhibitor FUT-175 on acute hemorrhagic pancreatitis in mice.
Effects of a new cholecystokinin antagonist, TS-941, on experimental acute pancreatitis in rats.
Failure of activated trypsin to cause experimental acute hemorrhagic pancreatitis.
Failure of Activated Trypsin to Cause Experimental Hemorrhagic Pancreatitis.
Methylprednisolone in acute canine hemorrhagic pancreatitis.
Prevention of increased pulmonary vascular permeability after pancreatitis by granulocyte depletion in sheep.
Prostacyclin and thromboxane in acute hemorrhagic pancreatitis in dogs.
Serum phospholipase A2, immunoreactive trypsin, and trypsin inhibitors during human acute pancreatitis.
Study of the effect of trypsin inhibitor in acute hemorrhagic pancreatitis in dogs.
The role of trypsin in the pathogenesis of acute hemorrhagic pancreatitis and the effect of an antitryptic agent in treatment.
Toxicity of hemorrhagic ascitic fluid associated with hemorrhagic pancreatitis.
TRYPSIN INHIBITOR IN ACUTE HEMORRHAGIC PANCREATITIS IN DOGS; EFFECT.
Use of crystalline soybean trypsin inhibitor in acute hemorrhagic pancreatitis in dogs.
[Evidence of the presence of trypsin in peripheral blood during acute hemorrhagic pancreatitis. Its role in the development of shock]
[Remarks on the trypsin activity of pancreatic juice during acute hemorrhagic pancreatitis treated with anti-enzymes.]
[The role of trypsin in the secondary manifestations of acute hemorrhagic pancreatitis]
Pancreatitis, Acute Necrotizing
A novel thermosensitive in-situ gel of gabexate mesilate for treatment of traumatic pancreatitis: An experimental study.
Acute hemorrhagic pancreatic necrosis in mice. Intraparenchymal activation of zymogens, and other enzyme changes in pancreas and serum.
Candesartan mediates microcirculation in acute necrotizing pancreatitis.
Cholinergic mediation of alcohol-induced experimental pancreatitis.
Continuous peritoneal dialysis in acute experimental pancreatitis in dogs. Effect of aprotinin in the dialysate medium.
Pancreatic fat necrosis and hemorrhagic necrosis as separate morphological and functional entities.
Relationship between enteric microecologic dysbiosis and bacterial translocation in acute necrotizing pancreatitis.
The effects of a thromboxane A2 synthesis inhibitor and a prostaglandin I2 analogue on experimental acute necrotizing pancreatitis in rats.
Therapeutic effects of continuous intraarterial antibiotic infusion in preventing pancreatic infection in experimental acute necrotizing pancreatitis.
[An experimental study on curative effect of Chinese medicine qing yi tang in acute necrotizing pancreatitis]
[Effect of hyperbaric oxygenation on experimental pancreas necrosis in pigs]
[Possibilities of the use of trypsinogen activation peptide in the pancreatic tissue in the diagnosis of pancreatic necrosis]
[Significance of bile and trypsin in the pathogenesis of acute pancreatic necrosis.]
[The pathogenesis of infection complicated by acute necrotizing pancreatitis: an experimental study]
Pancreatitis, Alcoholic
A review: acute and chronic effects of ethanol and alcoholic beverages on the pancreatic exocrine secretion in vivo and in vitro.
Alcoholic pancreatitis: new pathogenetic insights.
Different responses of serum cationic trypsinogen to secretin and bombesin in normal subjects and patients with chronic alcoholic pancreatitis.
Genetic and biochemical characterization of the E32del polymorphism in human mesotrypsinogen.
Keratin 8 Mutations Are Not Associated with Familial, Sporadic and Alcoholic Pancreatitis in a Population from the United States.
Trypsin activity. A new marker of acute alcoholic pancreatitis.
Usefulness of carbohydrate-deficient transferrin and trypsin activity in the diagnosis of acute alcoholic pancreatitis.
Pancreatitis, Chronic
A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis.
A Hypothesized Mechanism for Chronic Pancreatitis Caused by the N34S Mutation of Serine Protease Inhibitor Kazal-Type 1 Based on Conformational Studies.
A loss of function polymorphism (G191R) of anionic trypsinogen (PRSS2) confers protection against chronic pancreatitis.
A loss-of-function p.G191R variant in the anionic trypsinogen (PRSS2) gene in Japanese patients with pancreatic disorders.
A novel A121T mutation in human cationic trypsinogen associated with hereditary pancreatitis: functional data indicating a loss-of-function mutation influencing the R122 trypsin cleavage site.
A preclinical model of chronic pancreatitis driven by trypsinogen autoactivation.
A signal peptide cleavage site mutation in the cationic trypsinogen gene is strongly associated with chronic pancreatitis.
A study of the clinical utility of a 20-minute secretin-stimulated endoscopic pancreas function test and performance according to clinical variables.
Absence of mesotrypsinogen gene (PRSS3) copy number variations in patients with chronic pancreatitis.
Absence of PRSS1 mutations and association of SPINK1 trypsin inhibitor mutations in hereditary and non-hereditary chronic pancreatitis.
Analysis of the human pancreatic secretory trypsin inhibitor (PSTI) gene mutations in Japanese patients with chronic pancreatitis.
Assessing the pathological relevance of SPINK1 promoter variants.
Association of a new cationic trypsinogen gene mutation (V39A) with chronic pancreatitis in an Italian family.
Association of rare chymotrypsinogen C (CTRC) gene variations in patients with idiopathic chronic pancreatitis.
Bombesin, trypsin, and chronic pancreatitis.
Camostat, an oral trypsin inhibitor, reduces pancreatic fibrosis induced by repeated administration of a superoxide dismutase inhibitor in rats.
Can plasma human pancreatic polypeptide be used to detect diseases of the exocrine pancreas?
CFTR, PRSS1 and SPINK1 mutations in the development of pancreatitis in Brazilian patients.
CFTR, SPINK1, PRSS1, and CTRC Mutations Are Not Associated With Pancreatic Cancer in German Patients.
Chronic pancreatitis and cystic fibrosis.
Chronic pancreatitis associated with an activation peptide mutation that facilitates trypsin activation.
Chronic pancreatitis associated with the p.G208A variant of PRSS1 gene in a European patient.
Chronic pancreatitis resulting from genetic mutations in trypsin and trypsin inhibitors.
Chronic pancreatitis with alpha 1-antitrypsin deficiency: from uncontrolled trypsin activation?
Chronic pancreatitis.
Chronic pancreatitis: an update on genetic risk factors.
Chronic pancreatitis: controversies in etiology, diagnosis and treatment.
Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis.
Clinical and radiological outcome of patients suffering from chronic pancreatitis associated with gene mutations.
Clinical evidence of pathogenesis in chronic pancreatitis.
Clinical significance of serum pancreatic enzymes in the quiescent phase of chronic pancreatitis.
Clinical value of serum immunoreactive trypsin concentration.
Comparative study of serum trypsin levels and pancreatic exocrine function in chronic pancreatitis.
Complete analysis of the human mesotrypsinogen gene (PRSS3) in patients with chronic pancreatitis.
Cystic fibrosis gene mutations and pancreatitis risk: relation to epithelial ion transport and trypsin inhibitor gene mutations.
Defective binding of SPINK1 variants is an uncommon mechanism for impaired trypsin inhibition in chronic pancreatitis.
Deficient Endoplasmic Reticulum Acetyl-CoA Import in Pancreatic Acinar Cells Leads to Chronic Pancreatitis.
Deoxyribonuclease I serum activity in pancreatic cancer.
Detection of a large genomic deletion in the pancreatic secretory trypsin inhibitor (SPINK1) gene.
Determination of the relative contribution of three genes-the cystic fibrosis transmembrane conductance regulator gene, the cationic trypsinogen gene, and the pancreatic secretory trypsin inhibitor gene-to the etiology of idiopathic chronic pancreatitis.
Different effects of oral administration of synthetic trypsin inhibitor on the pancreas between cholecystokinin-A receptor gene knockout mice and wild type mice.
Different responses of serum cationic trypsinogen to secretin and bombesin in normal subjects and patients with chronic alcoholic pancreatitis.
Divergent roles of SPINK1 and PRSS2 variants in tropical calcific pancreatitis.
Duodenal secretion and fecal excretion of pancreatic elastase-1 in healthy humans and patients with chronic pancreatitis.
Effect of bombesin on serum immunoreactive trypsin in healthy subjects and in patients with chronic pancreatitis.
Effect of secretin upon the levels of pancreatic enzymes in blood serum.
Elastase-1 vs trypsin, lipase and amylase serum levels in pancreatic diseases.
Elevated intracellular trypsin exacerbates acute pancreatitis and chronic pancreatitis in mice.
Elevated serum levels of immunoreactive anionic trypsin (but not cationic trypsin) signals pancreatic disease.
Fractional urinary clearance of immunoreactive lipase in chronic pancreatic disease.
From acute to chronic pancreatitis: the role of mutations in the pancreatic secretory trypsin inhibitor gene.
Functional analysis of pancreatitis-associated missense mutations in the pancreatic secretory trypsin inhibitor (SPINK1) gene.
Gene Conversion between Cationic Trypsinogen (PRSS1) and the Pseudogene Trypsinogen 6 (PRSS3P2) in Patients with Chronic Pancreatitis.
Gene conversion between functional trypsinogen genes PRSS1 and PRSS2 associated with chronic pancreatitis in a six-year-old girl.
Genetic and biochemical characterization of the E32del polymorphism in human mesotrypsinogen.
Genetic aspects of chronic pancreatitis.
Genetic aspects of pancreatitis.
Genetic basis of chronic pancreatitis.
Genetic mutations in exons 3 and 4 of the pancreatic secretory trypsin inhibitor in patients with pancreatitis.
Genetic polymorphisms in alcoholic pancreatitis.
Genetic risk in chronic pancreatitis: the misfolding-dependent pathway.
Genetic Risk in Chronic Pancreatitis: The Trypsin-Dependent Pathway.
Genetics of chronic pancreatitis.
Genetics of pancreatitis: a guide for clinicians.
Germline mutations in CFTR and PSTI genes in chronic pancreatitis patients.
Hereditary chronic pancreatitis.
Hereditary pancreatitis and familial pancreatic cancer.
Hereditary pancreatitis and mutation of the trypsinogen gene.
Hereditary pancreatitis: clinical characteristics and diagnostic criteria in Japan.
Hereditary, familial, and idiopathic chronic pancreatitis are not associated with polymorphisms in the tumor necrosis factor alpha (TNF-alpha) promoter region or the TNF receptor 1 (TNFR1) gene.
High Incidence of PRSS1 and SPINK1 Mutations in Korean Children With Acute Recurrent and Chronic Pancreatitis.
Human cationic trypsinogen (PRSS1) variants and chronic pancreatitis.
Hydrogen breath test with glucose in exocrine pancreatic insufficiency.
Immunohistochemical localization of trypsinogen and trypsin in acute and chronic pancreatitis.
Immunoreactive serum trypsin in diseases of the pancreas.
In silico prioritization and further functional characterization of SPINK1 intronic variants.
Increased secretion of the pancreatic secretory trypsin inhibitor (PSTI-I, monitor peptide) during development of chronic pancreatitis in the WBN/Kob rat.
Interaction between trypsinogen isoforms in genetically determined pancreatitis: mutation E79K in cationic trypsin (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2).
Intestinal lysosomal enzymes in the diagnosis of pancreatic disease.
Intracellular activation of trypsinogen in transgenic mice induces acute but not chronic pancreatitis.
Intracellular autoactivation of human cationic trypsinogen mutants causes reduced trypsinogen secretion and acinar cell death.
Is genetic analysis helpful for diagnosing chronic pancreatitis in its early stage?
Lessons from hereditary pancreatitis.
Local clustering of PRSS1 R122H mutations in hereditary pancreatitis patients from Northern Germany.
Low Serum Trypsin Levels Predict Deep Pancreatic Cannulation Failure During Endoscopic Retrograde Cholangiopancreatography in Patients With Symptomatic Obstructive Chronic Pancreatitis.
Mesotrypsin Signature Mutation in a Chymotrypsin C (CTRC) Variant Associated with Chronic Pancreatitis.
Metastatic pancreatic adenocarcinoma associated with chronic calcific pancreatitis and a heterozygous SPINK1 N34S mutation.
Minigene analysis of intronic variants in common SPINK1 haplotypes associated with chronic pancreatitis.
Missense mutations in pancreatic secretory trypsin inhibitor (SPINK1) cause intracellular retention and degradation.
Molecular size distribution of immunoreactive trypsin and renal tubular dysfunction: role in trypsin plasma-urine transfer.
Molecular understanding of chronic pancreatitis: a perspective on the future.
Motion--genetic testing is useful in the diagnosis of nonhereditary pancreatic conditions: arguments against the motion.
Motion--genetic testing is useful in the diagnosis of nonhereditary pancreatic conditions: arguments for the motion.
Mutation analysis of the cystic fibrosis transmembrane conductance regulator (CFTR) gene, the cationic trypsinogen (PRSS1) gene, and the serine protease inhibitor, Kazal type 1 (SPINK1) gene in patients with alcoholic chronic pancreatitis.
Mutation in the SPINK1 trypsin inhibitor gene, alcohol use, and chronic pancreatitis.
Mutation That Promotes Activation of Trypsinogen Increases Severity of Secretagogue-Induced Pancreatitis in Mice.
Mutational analysis of ATP8B1 in patients with chronic pancreatitis.
Mutational analysis of the human pancreatic secretory trypsin inhibitor (PSTI) gene in hereditary and sporadic chronic pancreatitis.
Mutational analysis of the pancreatic secretory trypsin inhibitor gene in familial and juvenile pancreatitis in Japan.
Mutational screening of patients with nonalcoholic chronic pancreatitis: identification of further trypsinogen variants.
Mutational screening of the cationic trypsinogen gene in a large cohort of subjects with idiopathic chronic pancreatitis.
Mutations in serine protease inhibitor Kazal type 1 are strongly associated with chronic pancreatitis.
Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis.
Mutations of cationic trypsinogen in chronic pancreatitis.
Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis.
Mutations of the cationic trypsinogen gene in hereditary and non-hereditary pancreatitis.
Mutations of the cationic trypsinogen gene in patients with chronic pancreatitis.
Mutations of the pancreatic secretory trypsin inhibitor (PSTI) gene in idiopathic chronic pancreatitis.
Natural single-nucleotide deletion in chymotrypsinogen C gene increases severity of secretagogue-induced pancreatitis in C57BL/6 mice.
Never conclude with a negative result, explore all possibilities before changing your hypothesis. An interview with Dr. Catherine Figarella, former Director Groupe de Recherche sur les Glandes Exocrines, Faculté de Médecine, Marseille, France; Active Member of the Board of the French Cystic Fibrosis Association: 'Vaincre la Mucoviscidose'. Interview by Martín E. Fernández-Zapico.
Novel Pathogenic PRSS1 Variant p.Glu190Lys in a Case of Chronic Pancreatitis.
Pancreatic cancer risk in hereditary pancreatitis.
Pancreatic enzyme synthesis in pancreatic disease.
Pancreatic secretion of zinc and copper in normal subjects and in patients with chronic pancreatitis.
Pancreatic secretory trypsin inhibitor (SPINK1) gene mutations in patients with acute pancreatitis.
Pancreatic secretory trypsin inhibitor I reduces the severity of chronic pancreatitis in mice overexpressing interleukin-1? in the pancreas.
Pancreatitis in childhood.
Pathogenic cellular role of the p.L104P human cationic trypsinogen variant in chronic pancreatitis.
Physiological evaluation of the severity of pancreatic exocrine dysfunction during endoscopy.
Plasma trypsin in chronic pancreatitis and pancreatic adenocarcinoma.
Protease-Sensitive Pancreatic Lipase Variants Are Associated With Early Onset Chronic Pancreatitis.
Protection against chronic pancreatitis and pancreatic fibrosis in mice overexpressing pancreatic secretory trypsin inhibitor.
PRSS1 and SPINK1 Mutations in Alcoholic and Idiopathic Chronic Pancreatitis.
PRSS1 and SPINK1 mutations in idiopathic chronic and recurrent acute pancreatitis.
PRSS1 mutation: a possible pathomechanism of pancreatic carcinogenesis and pancreatic cancer.
Quantitation of tryptic responses to endogenous and exogenous stimulation in chronic pancreatitis.
Real-Time Label-Free Kinetics Monitoring of Trypsin-Catalyzed Ester Hydrolysis by a Nanopore Sensor.
REG I as a marker for human pancreatic acinoductular cells.
Relation between serum cathodic trypsinogen levels and exocrine pancreatic function.
Relationship between PABA and Lundh tests: lack of influence of duodenal pH in vivo.
Relationship of basal and postprandial intraduodenal bile acid concentrations and plasma cholecystokinin levels with abdominal pain in patients with chronic pancreatitis.
Relevance of variants in serum antiproteinases for the course of chronic pancreatitis.
Renal factors in serum trypsinogen 1 metabolism and excretion in chronic pancreatic disease.
Renal handling of amylase and immunoreactive trypsin in pancreatic cancer and chronic pancreatitis.
Renal tubular dysfunction in pancreatic cancer and chronic pancreatitis.
Reversibility of exocrine pancreatic failure in chronic pancreatitis.
Selectively aspirated pure pancreatic secretion. Viscosity, trypsin activity, protein concentration and lactoferrin content of pancreatic juice in chronic pancreatitis.
Serine protease inhibitor Kazal type 1 mutations and pancreatitis.
Serine protease inhibitor kazal type 1 mutations and pancreatitis.
Serum elastase 1 and immunoreactive trypsin in chronic pancreatic disease: is there any relationship with trypsin inhibitors?
Serum elastase 1 in chronic pancreatic disease.
Serum elastase 1 in inflammatory pancreatic and gastrointestinal diseases and in renal insufficiency. A comparison with other serum pancreatic enzymes.
Serum immunoreactive trypsin after secretin stimulation in chronic pancreatitis.
Serum immunoreactive trypsin concentration after a Lundh meal. Its value in the diagnosis of pancreatic disease.
Serum immunoreactive trypsin response to secretin injection in patients with chronic pancreatitis.
Serum immunoreactive trypsin, pancreatic polypeptide, and pancreatic isoamylase as diagnostic tests for chronic pancreatitis.
Signal peptide variants that impair secretion of pancreatic secretory trypsin inhibitor (SPINK1) cause autosomal dominant hereditary pancreatitis.
SPINK1 is a susceptibility gene for fibrocalculous pancreatic diabetes in subjects from the Indian subcontinent.
SPINK1 mutations are associated with multiple phenotypes.
SPINK1/PSTI mutations are associated with tropical pancreatitis in Bangladesh. A preliminary report.
SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis.
Susceptibility to pancreatitis related to PSTI/SPINK1 expression.
The A16V signal peptide cleavage site mutation in the cationic trypsinogen gene and chronic pancreatitis.
The course of genetically determined chronic pancreatitis.
The N34S mutation of SPINK1 (PSTI) is associated with a familial pattern of idiopathic chronic pancreatitis but does not cause the disease.
The noninvasive biochemical diagnosis of gastrointestinal disease, with special reference to children.
The Prevalence of Cationic Trypsinogen (PRSS1) and Serine Protease Inhibitor, Kazal Type 1 (SPINK1) Gene Mutations in Polish Patients with Alcoholic and Idiopathic Chronic Pancreatitis.
The relative values of serum immuno-reactive trypsin concentration and total amylase activity in the diagnosis of mumps, chronic renal failure, and pancreatic disease.
The spectrum of complications of hereditary pancreatitis. Is this a model for future gene therapy?
Trypsin and lactoferrin levels in pure pancreatic juice in patients with pancreatic disease.
Trypsin radioimmunoassay in the diagnosis of chronic pancreatitis.
Trypsin/creatinine clearance ratio and serum immunoreactive trypsin in digestive and pancreatic diseases.
Tumor-associated trypsin inhibitor in patients with chronic pancreatic diseases.
Tumour-associated trypsin inhibitor in the diagnosis of pancreatic carcinoma.
Two cases of chronic pancreatitis associated with anomalous pancreaticobiliary ductal union and SPINK1 mutation.
Two novel severe mutations in the pancreatic secretory trypsin inhibitor gene (SPINK1) cause familial and/or hereditary pancreatitis.
Urinary immunoreactive trypsin excretion: a non-invasive screening test for pancreatic cancer.
Viscosity and trypsin activity of pure pancreatic juice in chronic pancreatitis.
[A case of chronic pancreatitis in a young woman with the cationic trypsinogen (PRSS1) gene mutation]
[Antigenic properities of trypsin in chronic pancreatitis]
[Chronic pancreatitis--pancreas cancer: influence of genetic factors]
[Clinical implications of genetic risk factors of chronic pancreatitis]
[Concentration of trypsin and C-peptide in the sera of patients with chronic pancreatitis]
[Diagnostic significance of pancreatic serum-enzyme patterns after stimulation with secretin in chronic pancreatitis (author's transl)]
[Effect of pancreatic secretory trypsin gene mutations on the development of chronic pancreatitis].
[Evaluation of measuring serum trypsin by radioimmunoassay and clinical application for the study on the exocrine function in diabetics (author's transl)]
[Evaluation of the vegetable oil taken up into the duodenum as a factor in pancreozymin liberation in healthy persons and in digestive organ diseases]
[Fibrosis markers in heavy alcohol drinkers]
[Genetic risk factors in chronic pancreatitis]
[Genetic risk factors in pancreatic diseases--significance for general practice]
[Hereditary pancreatitis]
[Immunoreactive trypsin in the blood serum of patients with endogenous hypercorticism]
[Laboratory diagnosis of pancreatitis and pancreatic cancer]
[Mutations of SPINK1 and PRSS1 gene in Korean patients with chronic pancreatitis]
[Mutations of the pancreatic secretory trypsin inhibitor. Is the cause of chronic pancreatitis now known?]
[Radio-immunologic measurement of trypsin in chronic pancreatitis. Preliminary results]
[Role of cationic trypsinogen gene (PRSS-gene) mutations in the pathogenesis of chronic pancreatitis]
[Serum immunoreactive trypsin in chronic pancreatitis patients]
[Significance of trypsinogen gene mutations in the etiology of hereditary pancreatitis]
[Study of an optimal biological profile for demonstrating pancreatic involvement in acute abdominal syndrome]
[The effect of a protein-rich diet on the trypsin activity in the blood serum of patients with chronic pancreatitis]
[The Pancreas Study Group: Inhibition of pancreas secretion and trypsin activity. Mechanisms and importance of therapy of acute and chronic pancreatitis]
[The relation between the activity of trypsin and trypsin inhibitor in the serum and the status of the blood coagulation and anticoagulation system in patients with chronic pancreatitis]
[The significance of trypsin, amylase and lipase activities in the blood serum for the differential,diagnosis of chronic pancreatitis and other diseases of the abdominal organs]
[Trypsin and C-peptide concentration in the blood serum of patients with chronic pancreatitis]
Pancreatitis, Graft
Characterization of immunoreactive trypsin as a means of differentiating graft pancreatitis and allograft rejection after porcine pancreatic transplantation.
Papilloma
A direct cytogenetic technique for mouse skin carcinomas and papillomas.
Organotypic (raft) culture of biopsy-derived upper respiratory epithelium.
Paralysis
Differential gene expression profiles in the venom gland/sac of Eumenes pomiformis (Hymenoptera: Eumenidae).
Paramyxoviridae Infections
Effect of trypsin on reproduction of type 4 parainfluenza virus in Vero cell cultures under fluid overlay.
Influence of trypsin on the infectivity and biological properties or parainfluenza type 2 type 2 (croup-associated) virus in Vero cells.
Replication and plaque formation of parainfluenza viruses in an established line of monkey kidney cells.
Sensitive plaque neutralization assay for parainfluenza virus types 1, 2, and 3 and respiratory syncytial virus.
Susceptibility of continuous lines of monkey kidney cells to influenza and parainfluenza viruses in the presence of trypsin.
Parasitic Diseases
Induction of some digestive enzymes in the midgut of the sandfly Phlebotomus langeroni after sugar and blood meals.
Paratuberculosis
A technique for the purification of Mycobacterium paratuberculosis from the ileal mucosa of infected cattle.
Parkinson Disease
Altered Expression of Brain Proteinase-Activated Receptor-2, Trypsin-2 and Serpin Proteinase Inhibitors in Parkinson's Disease.
Parotitis
[Acute hemorrhagic necrotic parotitis caused by injection of trypsin into the parotid duct; the preventive effect of upper cervical sympathectomy.]
[Trypsin treatment of protracted forms of nervous system lesions of parotitis etiology]
Pelvic Inflammatory Disease
Concentrations of tumor-associated trypsin inhibitor and C-reactive protein in serum in acute pelvic inflammatory disease.
Pemphigoid, Bullous
Pemphigoid, pemphigus and Pr antigens in adult human keratinocytes grown on nonviable substrates.
The use of human pemphigoid autoantibodies to study the fate of epidermal basal cell hemidesmosomes after trypsin dissociation.
Pemphigus
Anti-cell surface pemphigus autoantibody stimulates plasminogen activator activity of human epidermal cells. A mechanism for the loss of epidermal cohesion and blister formation.
Anti-epidermal-cell-surface pemphigus antibody detaches viable epidermal cells from culture plates by activation of proteinase.
Corticosteroids, aurothioglucose and soybean trypsin inhibitor do not prevent pemphigus antibody-induced acantholysis in vitro.
Pemphigus serum-induced loss of microvilli from human epidermal cells.
The pathogenic role of pemphigus antibodies and proteinase in epidermal acantholysis.
Peptic Ulcer
The mucous neck cell in the human gastric corpus: a distinctive, functional cell lineage.
Treatment of peptic ulcer by use of intramuscular trypsin.
[Cholecystokinin-pancreozymin excretion and the state of the blood trypsin inhibitor system after the surgical treatment of peptic ulcer]
[Effect of the alimentary factor on certain indices of the functional state of the pancreas in young peptic ulcer patients and atrophic gastritis patients]
[Kallikrein-kinin and trypsin inhibiting system of blood in patients with peptic ulcer]
Peptic Ulcer Perforation
Serum trypsin levels in acute pancreatic and non-pancreatic abdominal conditions.
Periapical Diseases
Pulp Regeneration: Current Approaches, Challenges, and Novel Rejuvenating Strategies for an Aging Population.
Periodontal Diseases
Platelet activation by Protease I of Porphyromonas gingivalis W83.
Selective removal of human DNA from metagenomic DNA samples extracted from dental plaque.
The optimization of the BANA test as a screening instrument for gingivitis among subjects seeking dental treatment.
Periodontal Pocket
Inhibitory effect of serum globulins on the adhesion of Prevotella nigrescens to hydroxyapatite.
Periodontitis
Characterization of the trypsin-like enzymes of Porphyromonas gingivalis W83 using a radiolabelled active-site-directed inhibitor.
Influence of anticholinergic drugs on the development of an experimental periodontitis model.
Reflectance method for simple determination of proteinase activity in microliter samples of a complex serum-like fluid.
Salivary collagenase. Origin, characteristics and relationship to periodontal health.
Trypsin, T. denticola and P. gingivalis levels as diagnostic markers for periodontitis.
[Markers of periodontal destruction in saliva of periodontitis patients]
[The influence of electrophoresis on the penetration and distribution of trypsin into dental tissues and periodontium in experimental periodontitis (radioisotope studies)]
[USE OF TRYPSIN IN THE TREATMENT OF PERIODONTITIS.]
Peripheral Arterial Disease
[Study of cantharides blister fluid in the analysis of the mechanism of action of trypsin in the treatment of chronic peripheral arterial diseases.]
Peripheral Vascular Diseases
Clinical studies on the use of parenteral trypsin and chymotrypsin in peripheral vascular disease.
Trypsin in peripheral vascular diseases; review and report on treatment of 210 patients.
Trypsin in the treatment of local complications of peripheral vascular disease in diabetes mellitus.
Peritoneal Fibrosis
A short review of experimental peritoneal sclerosis: from mice to men.
Peritonitis
"Two-route chemotherapy" using cis-diamminedichloroplatinum(II) and its antidote, sodium thiosulfate, combined with angiotensin II is effective against peritoneally disseminated cancer in rats.
Comparative properties of feline coronaviruses in vitro.
Elevated pancreatic secretory trypsin inhibitor levels during severe inflammatory disease, renal insufficiency, and after various surgical procedures.
Experimental inquiry into the significance of trypsin in bile peritonitis, with particular reference to the human secretions.
Pancreatic injuries in rats with fecal peritonitis: protective effect of a new synthetic protease inhibitor, sepinostat mesilate (FUT-187).
[Absorption of trypsin and its inhibitors from the abdominal cavity in experimental peritonitis]
[Effect of proteolytic enzymes on kanamycin pharmacokinetics in experimental suppurative infection]
[The activity of trypsin and proteolytic inhibitors in complicated forms of appendicitis in children]
[The protein components of the acid-soluble fraction of normal human blood plasma and in peritonitis patients]
Persistent Infection
In Vitro Variant Surface Antigen Expression in Plasmodium falciparum Parasites from a Semi-Immune Individual Is Not Correlated with Var Gene Transcription.
Viruses and cells with mutations affecting viral entry are selected during persistent rotavirus infections of MA104 cells.
Peutz-Jeghers Syndrome
Familial pancreatic carcinoma in Jews.
Pheochromocytoma
Cholecystokinin, gastrin and their precursors in pheochromocytomas.
Phlebitis
Retinal pathologic changes in multiple sclerosis.
Retinal phlebitis in the Irvine-Gass syndrome.
Photophobia
Spectroscopic study of trypsin, heat and triton X-100-induced denaturation of the chlorophyll-binding protein CP43.
Pick Disease of the Brain
Alzheimer dementia and Pick's disease: neurofibrillary tangles and Pick bodies are associated with identical phosphorylated neurofilament epitopes.
Pituitary Neoplasms
Estrogen-induced hyperplasia and neoplasia in the rat anterior pituitary gland. An immunohistochemical study.
The exocrine protein trypsinogen is targeted into the secretory granules of an endocrine cell line: studies by gene transfer.
Plasmacytoma
Cultured mouse marrow stromal cell lines. II. Distinct subtypes differing in morphology, collagen types, myelopoietic factors, and leukemic cell growth modulating activities.
Evidence for a functional receptor for cyclosporin A on the surface of lymphocytes.
Patterns of immunoglobulin staining in paraffin-embedded malignant lymphomas.
Pleural Effusion
Concentration of tumor-associated trypsin inhibitor (TATI) in pleural effusions.
Tumor-associated trypsin inhibitor (TATI) in pleural effusions.
[Association of trypsin and chymotrypsin in pleural effusions of diverse etiology]
[Elevated trypsin level in chronic pancreatic pleural effusion]
[Tissue polypeptide antigen and tumor trypsin inhibitor in pleural effusions of various etiologies]
Pleural Effusion, Malignant
[Advances of human epididymis protein 4 in lung cancer].
Pleurisy
Are proteases used as anti-inflammatory agents in reality accelerating the inflammatory process?
Effects of an orally active non-peptide bradykinin B2 receptor antagonist, FR173657, on plasma exudation in rat carrageenin-induced pleurisy.
Proteinase-activated receptor-4 plays a major role in the recruitment of neutrophils induced by trypsin or carrageenan during pleurisy in mice.
Rat pleurisy induced by kaolin or croton oil: time course of fluid accumulation and white cell migration.
Pneumonia
A 2S Albumin from the Seed Cake of Ricinus communis Inhibits Trypsin and Has Strong Antibacterial Activity against Human Pathogenic Bacteria.
A plant proteinase inhibitor from enterolobium contortisiliquum attenuates airway hyperresponsiveness, inflammation and remodeling in a mouse model of asthma.
Aflatoxin G1 induced TNF-?-dependent lung inflammation to enhance DNA damage in alveolar epithelial cells.
Comparison of three methods for the determination of serum alpha-1-antitrypsin in patients with pulmonary diseases.
Elevated pancreatic secretory trypsin inhibitor levels during severe inflammatory disease, renal insufficiency, and after various surgical procedures.
IL-1? is a key cytokine that induces trypsin upregulation in the influenza virus-cytokine-trypsin cycle.
Lung adenocarcinoma-related TNF-?-dependent inflammation upregulates MHC-II on alveolar type II cells through CXCR-2 to contribute to Treg expansion.
Monoclonal immunoglobulin A antibody to the major outer membrane protein of the Chlamydia trachomatis mouse pneumonitis biovar protects mice against a chlamydial genital challenge.
Nelfinavir/ritonavir reduces acinar injury but not inflammation during mouse caerulein pancreatitis.
Sendai virus infection up-regulates trypsin I and matrix metalloproteinase-9, triggering viral multiplication and matrix degradation in rat lungs and lung L2 cells.
The effect of trypsin and other enzymes on feline pneumonitis virus.
[Diagnostic value of using a 2.5 per cent solution of trypsin in pulmonary tuberculosis and chronic pneumonia in combination with bronchial asthma]
[Treatment of interstitial pneumocystic pneumonia by trypsin aerosol.]
Pneumonia, Bacterial
Growth activation of influenza virus by trypsin and effect of T-705 (favipiravir) on trypsin-optimized growth condition.
The effect of intramuscular trypsin in acute bacterial pneumonia.
Pneumonia, Pneumocystis
?-Glucans Are Masked but Contribute to Pulmonary Inflammation During Pneumocystis Pneumonia.
Pneumothorax
[A case of spontaneous pneumothorax with gas embolism in intratracheal trypsin instillation]
[Complicated spontaneous pneumothorax. Treatment with trypsin.]
[Recurrent pneumothorax: its association with alpha-1 trypsin deficiency.]
[Spontaneous pneumothorax with gas embolism during intratracheal administration of trypsin]
Poliomyelitis
Immunogenicity of trypsin treated type 2 and type 3 poliovirus in rats.
Intramuscular trypsin in acute poliomyelitis.
Studies of the inactivation of poliomyelitis virus by formaldehyde; effect of initial virus concentration, of mechanical stirring during inactivation and of digestion with trypsin prior to initiation of inactivation.
Trypsin diminishes the rat potency of polio serotype 3.
Trypsin in poliomyelitis patients with tracheotomy.
Poliomyelitis, Bulbar
Aerosol trypsin in respiratory complications of bulbar poliomyelitis; report of a case.
Atelectasis; physiopathology and treatment; special reference to its occurrence in bulbar poliomyelitis, and to a suggested therapeutic aid by the intrabronchial administration of trypsin.
Polycythemia
Postnatal development of liver and exocrine pancreas in polycythemic newborn infants.
Porcine Reproductive and Respiratory Syndrome
Monitoring activation of the antiviral pattern recognition receptors RIG-I and PKR by limited protease digestion and native PAGE.
Prader-Willi Syndrome
The Prader-Willi syndrome with a 15/3 translocation.
Pre-Eclampsia
How to lower perinatal mortality? Perinatal care in Japan.
The effect of severe pre-eclampsia on the pancreas: changes in the serum cationic trypsinogen and pancreatic amylase.
Urinary trypsin inhibitor may have a protective effect on endothelial cells in preeclampsia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Conformational changes of rBTI from buckwheat upon binding to trypsin: implications for the role of the P(8)' residue in the potato inhibitor I family.
Trypsin encoding PRSS1-PRSS2 variation influence the risk of asparaginase-associated pancreatitis in children with acute lymphoblastic leukemia: a Ponte di Legno toxicity working group report.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Suppressive activity of protease inhibitors from buckwheat seeds against human T-acute lymphoblastic leukemia cell lines.
[Preparation of immobilized trypsin micro monolithic column and its application to rapid digestion of trace proteins].
Pregnancy Complications
Plasma PP13 and urinary GAGs/PGs as early markers of pre-eclampsia.
Premature Birth
Randomized trial of the efficacy of intravaginal ulinastatin administration for the prevention of preterm birth in women with a singleton pregnancy and both cervical shortening and inflammation of lower genital tract.
Prostatic Neoplasms
Conformational and biochemical analysis of the cyclic peptides which modulate serine protease activity.
Editorial comment on: Increased expression of tumor-associated trypsin inhibitor, TATI, in prostate cancer and in androgen-independent 22Rv1 cells.
Enzyme cleavable nanoparticles from peptide based triblock copolymers.
Identification and quantification of peptides and proteins secreted from prostate epithelial cells by unbiased liquid chromatography tandem mass spectrometry using goodness of fit and analysis of variance.
Increased expression of tumor-associated trypsin inhibitor, TATI, in prostate cancer and in androgen-independent 22Rv1 cells.
Prostate-specific antigen and other prostate-derived proteases cleave IGFBP-3, but prostate cancer is not associated with proteolytically cleaved circulating IGFBP-3.
Proteolytic modification of swelling-activated Cl- current in LNCaP prostate cancer epithelial cells.
Proteomic analysis of pancreatic secretory trypsin inhibitor/tumor-associated trypsin inhibitor from urine of patients with pancreatitis or prostate cancer.
PRSS3/mesotrypsin is a therapeutic target for metastatic prostate cancer.
[Effect of intracellular trypsin on characteristics of voltage-dependent inactivation of chloride currents in prostatic cancer cells]
Protein Deficiency
Exocrine pancreatic function in protein-deficient patas monkeys studied by means of a test meal and an indirect pancreatic function test.
[Response of the rat pancreas to the effects of secretin and pancreozymin under conditions of different nutrition]
Protein-Energy Malnutrition
Serum trypsin as measure of pancreatic exocrine function in children with protein calorie malnutrition.
[Comparative study of the effects of 2 types of protein-energy malnutrition followed by a balanced realimentation on trypsin and chymotrypsin activity of the pancreas and the pancreatic juice of the rat]
[Serum cationic trypsinogen: marker of exocrine pancreatic dysfunction in children with protein-calorie malnutrition]
Protein-Losing Enteropathies
Enteropathy-type T-cell lymphoma that was pathologically diagnosed as celiac disease.
Proteinuria
Antimicrobial gentamicin activity in the presence of exogenous protease inhibitor (Bowman-Birk inhibitor) in gentamicin-induced nephrotoxicity in rats.
Effect of interaction between gentamicin and pyridoxal-5-phosphate on functional and metabolic parameters in kidneys of female Sprague-Dawley rats.
Enhanced urinary trypsin inhibitory activity in gentamicin-induced nephrotoxicity in rats.
Urinary cancer-related protein EDC1 and serum inter-alpha trypsin inhibitor in breast cancer.
Urine protease and antiprotease activity in experimental aminonucleoside nephrotoxicity.
[Clinical value of the determination of urinary antitrypsin activity]
Pruritus
Complementary roles of murine NaV1.7, NaV1.8 and NaV1.9 in acute itch signalling.
Decreased plasma kallikrein 5 concentrations in patients with chronic spontaneous urticaria.
Evidence for the role of neurogenic inflammation components in trypsin-elicited scratching behaviour in mice.
Latency and duration of pruritus elicited by trypsin in aged patients with itching eczema and psoriasis.
Patterns among Patients with Chronic Pruritus: A Retrospective Analysis of 170 Patients.
Scratch induction in the rat by intradermal serotonin: a model for pruritus.
Pseudomonas Infections
Immunodepletion of albumin for two-dimensional gel detection of new mouse acute-phase protein and other plasma proteins.
Protease-cleaved iron-transferrin augments oxidant-mediated endothelial cell injury via hydroxyl radical formation.
Pseudomyxoma Peritonei
Pseudomyxoma peritonei: failure of activated trypsin to modify the course of the disease.
Pseudorabies
Demonstration of Aujeszky's disease virus antigen in trypsin-digested paraffin-embedded tissue sections by immunofluorescence.
Differentiation of vaccine strains and field isolates of pseudorabies (Aujeszky's disease) virus: trypsin sensitivity and mouse virulence markers.
Distribution of B-cell epitopes on the pseudorabies virus glycoprotein B.
In vitro comparison between four variants of Aujeszky's disease virus.
Trypsin increases pseudorabies virus production through activation of the ERK signalling pathway.
[Use of temperature, trypsin and biological tests for the intraspecies differentiation of local strains of Aujeszky's disease virus]
Pseudoxanthoma Elasticum
Effect of selective enzymatic digestions on skin biopsies from pseudoxanthoma elasticum: an ultrastructural study.
Psoriasis
Adenosine deaminase activity, trypsin inhibitory capacity and total antioxidant capacity in psoriasis.
Decreased specific anti-elastase activity in the uninvolved skin of patients with psoriasis.
Latency and duration of pruritus elicited by trypsin in aged patients with itching eczema and psoriasis.
Multiple pathways are involved in DNA degradation during keratinocyte terminal differentiation.
[Activity of peptide hydrolases and trypsin inhibitor in psoriasis]
Pulmonary Alveolar Proteinosis
Bronchoalveolar lavage with trypsin in pulmonary alveolar proteinosis.
Pulmonary alveolar proteinosis. Remission after therapy with trypsin and chymotrypsin.
Pulmonary alveolar proteinosis: successful treatment with aerosolized trypsin.
Trypsin aerosol treatment of pulmonary alveolar proteinosis. Case report.
Pulmonary Atelectasis
Aerosol trypsin in atelectasis neonatorum.
Atelectasis; physiopathology and treatment; special reference to its occurrence in bulbar poliomyelitis, and to a suggested therapeutic aid by the intrabronchial administration of trypsin.
The use of aerosol trypsin in atelectasis neonatorium.
The use of trypsin or streptokinase-streptodornase for the therapy and prevention of atelectasis.
[Pulmonary atelectasis and trypsin aerosols.]
Pulmonary Disease, Chronic Obstructive
Decrease in the alpha 1-proteinase inhibitor Spi3 in equine bronchoalveolar lavage fluid.
Interactions of neutrophil elastase, serum trypsin inhibitory activity, and smoking history as risk factors for chronic obstructive pulmonary disease in patients with MM, MZ, and ZZ phenotypes for alpha-antitrypsin.
Interactions of neutrophil elastase, serum trypsin inhibitory activity, and smoking history as risk factors for chronic obstructive pulmonary disease in patients with MM, MZ, and ZZ phenotypes for alpha1-antitrypsin.
Trypsin binding activity of alpha 2-macroglobulin in cystic fibrosis and other lung diseases.
Tumor-associated trypsin inhibitor (TATI) in the diagnosis of lung cancer.
[Correlations between chymase activity ,levels of tryptase, and eotaxin in the sputum of patients with chronic obstructive puhnonary disease and their clinical implications]
Pulmonary Edema
Ulinastatin Ameliorates Pulmonary Capillary Endothelial Permeability Induced by Sepsis Through Protection of Tight Junctions via Inhibition of TNF-? and Related Pathways.
Pulmonary Embolism
Pulmonary embolism complicating trypsin therapy.
The use of intravenous trypsin in experimental pulmonary embolism.
[Case of postoperative recurring pulmonary embolism cured with intramuscular trypsin associated with anticoagulant therapy.]
Pulmonary Emphysema
Chronic obstructive pulmonary disease and alpha-1-antitrypsin (Pi) variation: a family study.
Parenteral administration of trypsin triggers lung emphysema.
[Trypsin plus chymotrypsin in chronic bronchitic forms with pulmonary emphysema.]
Pulmonary Fibrosis
Imrecoxib Inhibits Paraquat-Induced Pulmonary Fibrosis through the NF-?B/Snail Signaling Pathway.
Loss of Shp2 in alveoli epithelia induces deregulated surfactant homeostasis, resulting in spontaneous pulmonary fibrosis.
[Biological effect of (60)Cogamma ray on alveolar type II cells and interstitial cells of alveoliar septum in radiation pulmonary injury.]
Pulpitis
The effect of a proteolytic enzyem mixture (Orenzyme-Forte) on experimentally induced pulpitis.
Purpura
[PROTEOLYTIC PROCESSES AND PURPURA INDUCED IN HYPERTENSIVE PATIENTS. EXPERIMENTAL STUDY. I. INFLUENCE OF TRYPSIN ON HEMORRHAGIC MANIFESTATIONS OF THE TOURNIQUET TEST IN HYPERTENSIVE PATIENTS.]
[PURPURA PROVOKED BY HYPERTHYROIDISM AND INFLUENCE ON THIS BY TRYPSIN AND A PROTEOLYTIC INHIBITOR.]
Pyelonephritis
[Activity of proteolytic enzymes and trypsin inhibitor in blood serum and kidney in pyelonephritis]
[Kallikrein, nonspecific proteases and trypsin inhibitor in the urine of patients with pyelonephritis]
Rabies
A simple technique for the rapid diagnosis of rabies in formalin-preserved brain.
Calculating rabies virus neutralizing antibodies titres by flow cytometry.
Diagnosis of rabies by immunofluorescence in trypsin-treated histologic sections.
Enhanced growth and plaquing of rabies virus in static chick embryo cell culture.
Immunofluorescent staining of rabies virus antigen in formalin-fixed tissue after treatment with trypsin.
Immunofluorescent staining of trypsinized formalin-fixed brain smears for rabies antigen: results compared with those obtained by standard methods for 221 suspect animal cases in Nigeria.
Immunological studies of a 21 kDa cellular component efficiently incorporated into rabies virion grown in a BHK-21 cell culture.
Increased immunofluorescent staining of rabies-infected, formalin-fixed brain tissue after pepsin and trypsin digestion.
pH-dependent hemolysis and cell fusion of rhabdoviruses.
Structure-function relationships and mode of replication of animal rhabdoviruses.
Trypsin promotes efficient influenza vaccine production in MDCK cells by interfering with the antiviral host response.
[Effect of trypsin and RNase on the morphology and biological properties of the rabies virus]
Rectal Neoplasms
Effects of radiation therapy on tissue and serum concentrations of tumour associated trypsin inhibitor and their prognostic significance in rectal cancer patients.
Evaluation of shell vial cell culture technique for the detection of bovine coronavirus.
[A case of local recurrence of rectal cancer successfully treated by UFT combined with two-route CDDP chemotherapy under the AT-II induced hypertension]
Relative Energy Deficiency in Sport
Technique for revealing the three-dimensional architecture of whole preserved spiculated invertebrates.
Renal Insufficiency
Elevated pancreatic secretory trypsin inhibitor levels during severe inflammatory disease, renal insufficiency, and after various surgical procedures.
Immunoreactive trypsin and pancreatic isoamylase activity in serum of patients with chronic renal failure or hepatic cirrhosis.
Pancreatic exocrine function in severe human chronic renal failure.
Plasma pancreatic trypsinogens in chronic renal failure and after nephrectomy.
Purification and amino acid analysis of plasma acid stable trypsin inhibitor.
RENAL INSUFFICIENCY FOLLOWING TRYPSIN INJECTION INTO THE RENAL ARTERIES.
Serum elastase 1 in inflammatory pancreatic and gastrointestinal diseases and in renal insufficiency. A comparison with other serum pancreatic enzymes.
Serum trypsin levels in acute pancreatic and non-pancreatic abdominal conditions.
[Immunoreactive trypsin in the serum of normal children and children with gastrointestinal diseases]
Renal Insufficiency, Chronic
Evidence for the participation of proteases on protein catabolism during hypercatabolic renal failure.
Reperfusion Injury
Attenuation of graft ischemia-reperfusion injury by urinary trypsin inhibitor in mouse intestinal transplantation.
Autodigestion by migrated trypsin is a major factor in small intestinal ischemia-reperfusion injury.
Effects of ulinastatin on pulmonary artery pressure during abdominal aortic aneurysmectomy.
Effects of ulinastatin, a urinary trypsin inhibitor, on synaptic plasticity and spatial memory in a rat model of cerebral ischemia/reperfusion injury.
Neuroprotective Effect of Ulinastatin on Spinal Cord Ischemia-Reperfusion Injury in Rabbits.
Neuroprotective effect of urinary trypsin inhibitor against focal cerebral ischemia-reperfusion injury in rats.
The Protective Effects of Trypsin Inhibitor on Hepatic Ischemia-Reperfusion Injury and Liver Graft Survival.
Ulinastatin attenuates reperfusion injury in the isolated blood-perfused rabbit heart.
Urinary Trypsin Inhibition: Cardioprotection via the Reperfusion Injury Salvage Kinase Pathway.
Urinary trypsin inhibitor ameliorates renal tissue oxygenation after ischemic reperfusion in rats.
Urinary trypsin inhibitor attenuates hepatic ischemia-reperfusion injury by reducing nuclear factor-kappa B activation.
Respiratory Distress Syndrome
Biochemical pathways of acute lung injury.
Evidence for pancreas injury in adult respiratory distress syndrome.
High expression of pulmonary proteinase-activated receptor 2 in acute and chronic lung injury in preterm infants.
Immunoreactive trypsin in the adult respiratory distress syndrome.
Intra-alveolar urinary trypsin inhibitor cannot inhibit polymorphonuclear elastase activity in the lung in postsurgical patients with acute respiratory distress syndrome.
Lidocaine attenuates acute lung injury induced by a combination of phospholipase A2 and trypsin.
Pulmonary trypsin-2 in the development of bronchopulmonary dysplasia in preterm infants.
Serum trypsin inhibitory capacity and the idiopathic respiratory distress syndrome.
Trypsin-like activity and thromboxane release in adult respiratory distress syndrome.
Umbilical cord serum trypsin inhibitor capacity and the idiopathic respiratory distress syndrome.
Up-regulation of trypsin and mesenchymal MMP-8 during development of hyperoxic lung injury in the rat.
Respiratory Tract Infections
Buccal and intramuscular trypsin in respiratory tract infection.
Potential use of Atlantic cod trypsin in biomedicine.
[The ?F508 mutation in cystic fibrosis patients.]
Retinal Perforations
[Experimental study on the retinal tear. 6. Observation on retinal vessels around the retinal tear by trypsin digestion method]
Retinal Telangiectasis
Flat preparations of the retinal vessels in Coats' disease.
Retinitis
Role of HIV and CMV in the pathogenesis of retinitis and retinal vasculopathy in AIDS patients.
Retinoblastoma
Identification of discrete structural domains in the retinoblastoma protein. Amino-terminal domain is required for its oligomerization.
Reye Syndrome
Serial alterations in the forms of immunoreactive pancreatic cationic trypsin in plasma from patients with acute pancreatitis.
Rh Isoimmunization
[Trypsin reaction in detection of Rh sensitization in pregnancy.]
Rhabdomyosarcoma
Cell survival and growth delay in rat R-1 tumours after radiation and vinblastine treatment.
Rheumatic Diseases
Serum inhibitors of elastase, trypsin, and plasmin in chronic rheumatic diseases.
[Comparative epidemiological study in patients with rheumatic diseases illustrated in a example of a treatment with non-steroidal anti- inflammatory drugs versus an oral enzyme combination preparation]
Rheumatic Fever
Quantitative studies on the total plasmin and the trypsin inhibitor of human blood serum; variations in the blood concentration of total plasmin and of trypsin inhibitor in streptococcal diseases with special reference to rheumatic fever.
Rhinitis
Protease-activated receptor 2 expression in trigeminal neurons innervating the rat nasal mucosa.
Rocky Mountain Spotted Fever
Identification of Rickettsia rickettsii in formalin-fixed, paraffin-embedded tissues by immunofluorescence.
Rotavirus Infections
Effects of antibodies, trypsin, and trypsin inhibitors on susceptibility of neonates to rotavirus infection.
Influence of soybean trypsin inhibitor on small bowel enzyme activities during rotavirus infection in malnourished infant mice.
Lipid composition and amino acid uptake during rotavirus infection and protection with trypsin inhibitor in malnourished infant mice.
Peroral immunization of microencapsulated human VP8 in combination with cholera toxin induces intestinal antibody responses.
Protection against neonatal rotavirus infection by breast milk antibodies and trypsin inhibitors.
Protective efficacy of trypsin inhibitor on the the gut following rotavirus infection in malnourished infant mice.
Rotavirus infection in newborn calves. I. Evaluation trials of certain enzymes in faeces.
Soybean trypsin inhibitor confers protection against rotavirus infection in infant mice.
The isolation, propagation and characterization of tissue-cultured equine rotaviruses.
Rubella
Detection of bovine viral diarrhoea virus nucleic acid, but not infectious virus, in bovine serum used for human vaccine manufacture.
Rubella virus haemagglutinin: association with a single virion glycoprotein.
[The agglutination of erythrocytes treated with trypsin with rubella virus antigen]
[The hemagglutination inhibition reaction in the diagnosis of rubella. Apropos of the critical and comparative study of 252 serums treated by heparin-MnCl2 and allowed to react with trypsin treated human O erytrocytes]
Sarcoma
Antithrombin improves the maternal and neonatal outcomes but not the angiogenic factors in extremely growth-restricted fetuses at <28 weeks of gestation.
Antitumor activity of Moringa oleifera (drumstick tree) flower trypsin inhibitor (MoFTI) in sarcoma 180-bearing mice.
Cell surface retention sequence binding protein-1 interacts with the v-sis gene product and platelet-derived growth factor beta-type receptor in simian sarcoma virus-transformed cells.
Field bean protease inhibitor preparations, unlike methotrexate, can completely suppress Yoshida sarcoma tumor in rats.
Immunological activity of regional lymph nodes in tumor-bearing mice.
Inflammatory cells in solid murine neoplasms. II. Cell types found throughout the course of Moloney sarcoma regression or progression.
Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2.
Surface proteins of fibroblast and sarcoma cells--their shedding and trypsin susceptibility.
Use of trypsin for rapid and efficient purification of murine sarcoma and leukemia virus.
Vascular sarcomas (probably angiosarcomas) transplanted from suspensions of liver cells from diethylnitrosamine-treated rats.
[Antineoplastic effects of carnosine and beta-alanine--physiological considerations of its antineoplastic effects]
Sarcoma 180
Proteolytic activities of mouse sarcoma 180 cells that are inhibited by Bowman-Birk and Kunitz protease inhibitors.
Sarcoma 37
The effects of trypsin on the size, viability and dry mass of sarcoma 37 cells.
Sarcoma, Avian
Activation of ornithine decarboxylase in monolayer cells treated with trypsin.
Analysis of the catalytic domain of phosphotransferase activity of two avian sarcoma virus-transforming proteins.
STUDIES IN ULTRAFILTRATION.
Scabies
A Proteomic Analysis of Sarcoptes scabiei (Acari: Sarcoptidae).
Schistosomiasis
Serum trypsin in hepatosplenic schistosomiasis in the Sudan.
Scrapie
Enhancement of immunohistochemical staining of scrapie proteins and immune cells within lymph nodes of early scrapie-infected sheep.
Normal and scrapie-associated forms of prion protein differ in their sensitivities to phospholipase and proteases in intact neuroblastoma cells.
Viroids and prions.
Seizures
A thought on the biological activities of black tea.
Protease-activated receptor-2 regulates trypsin expression in the brain and protects against seizures and epileptogenesis.
Relationship between nicotine-induced seizures and hippocampal nicotinic receptors.
The biochemical and behavioral effects of phospholipase A2 and morphine microinjections in the periaqueductal gray of the rat.
Sepsis
Beneficial effects of ulinastatin on gut barrier function in sepsis.
Effect of ulinastatin combined with thymosin alpha1 on sepsis: A systematic review and meta-analysis of Chinese and Indian patients.
Efficacy and safety of phlogenzym--a protease formulation, in sepsis in children.
Exocrine pancreatic dysfunction in sepsis.
High Serum Trypsin Levels and the -409 T/T Genotype of PRSS1 Gene Are Susceptible to Neonatal Sepsis.
Intravenous administration of ulinastatin (human urinary trypsin inhibitor) in severe sepsis: a multicenter randomized controlled study.
Optimization of plasma fluorogenic thrombin-generation assays.
Pancreatic injuries in rats with fecal peritonitis: protective effect of a new synthetic protease inhibitor, sepinostat mesilate (FUT-187).
The activation of neutrophil elastase-mediated fibrinolysis is not sufficient to overcome the fibrinolytic shutdown of disseminated intravascular coagulation associated with systemic inflammation.
Ulinastatin Ameliorates Pulmonary Capillary Endothelial Permeability Induced by Sepsis Through Protection of Tight Junctions via Inhibition of TNF-? and Related Pathways.
Urinary trypsin inhibitor treatment ameliorates acute lung and liver injury resulting from sepsis in a rat model.
[Effect on hemostasis and thrombogenesis by septic processes especially in childhood]
Severe Acute Respiratory Syndrome
Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites.
Entry from the cell surface of severe acute respiratory syndrome coronavirus with cleaved S protein as revealed by pseudotype virus bearing cleaved S protein.
Identification of 22 N-glycosites on spike glycoprotein of SARS-CoV-2 and accessible surface glycopeptide motifs: implications for vaccination and antibody therapeutics.
Protease-mediated entry via the endosome of human coronavirus 229E.
The Role of Pulmonary Surfactants in the Treatment of Acute Respiratory Distress Syndrome in COVID-19.
Sexually Transmitted Diseases
Secretion of miraculin through the function of a signal peptide conserved in the Kunitz-type soybean trypsin inhibitor family.
Shock, Cardiogenic
Effect of hemorrhagic and nortriptyline-induced shock on the porcine pancreas as evaluated by changes in serum cationic trypsin-like immunoreactivity.
Shock, Septic
Effect of intravenous and intraduodenal administration of Escherichia coli endotoxin on the porcine pancreas as evaluated by changes in the serum cationic trypsin-like immunoreactivity.
Exocrine pancreatic dysfunction in sepsis.
Exocrine pancreatic function in critically ill patients: septic shock versus non-septic patients.
Further evidence of bradykinin involvement in septic shock: reduction of kinin production in vivo and improved survival in rats by use of polymer tailored SBTI with longer t1/2.
Inhibition of lipopolysaccharide-induced tissue factor expression in monocytes by urinary trypsin inhibitor in vitro and in vivo.
Urinary trypsin inhibitor reduces inflammatory response in kidney induced by lipopolysaccharide.
[Therapeutic effects and influence on the urinary enzyme activity of human urinary trypsin inhibitor (urinastatin) in cases with acute renal failure--changes in the urinary activities of NAG and AAP]
Short Bowel Syndrome
Inhibition of postprandial pancreatic and biliary secretion by loperamide in patients with short bowel syndrome.
Shwartzman Phenomenon
Effect of trypsin inhibitors on Shwartzman phenomenon.
Potentiation of the local Shwartzman phenomenon by trypsin.
Silicosis
[On the efficacy of treatment of silicosis with trypsin aerosol]
[STUDY OF THE EFFECT OF TRYPSIN AEROSOL INHALATION THERAPY ON SILICOSIS.]
[The effect of trypsin of the development and course of experimental silicosis]
Sinusitis
A protease inhibitor from human allergic nasal secretions.
Differences in physicochemical properties between tissue plasminogen activators from human paranasal mucous membrane and pig heart.
Low sweat electrolytes in a patient with cystic fibrosis.
Skin Diseases
Avidin-biotin-peroxidase complex immunohistochemistry to detect immunoglobulin in formalin fixed skin biopsies in canine autoimmune skin disease.
Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition.
Failure of intramuscular trypsin to alter the course of certain inflammatory dermatoses.
The treatment of selected dermatoses with crystalline trypsin ointment.
Tissue Kallikrein Inhibitors Based on the Sunflower Trypsin Inhibitor Scaffold - A Potential Therapeutic Intervention for Skin Diseases.
[EXPERIMENTAL AND CLINICAL STUDIES ON THE EFFECTIVENESS OF KALLIKREIN- TRYPSIN INHIBITOR (TRASYLOL) IN DERMATOSES.]
[Therapeutic effect of trypsin in skin diseases.]
Sleep Apnea, Obstructive
[The changes of some vasoactive substances after operation in patients with obstructive sleep apnea-hypopnea syndrome]
Small Cell Lung Carcinoma
P-selectin mediates adhesion of platelets to neuroblastoma and small cell lung cancer.
Smallpox
[Use of immobilized proteinases for purification of sheep smallpox virus]
Speech Disorders
The Prader-Willi syndrome with a 15/3 translocation.
Spinal Cord Injuries
Spinal cord transection: a quantitative analysis of elements of the connective tissue matrix formed within the site of lesion following administration of piromen, cytoxan or trypsin.
Spinal Osteochondrosis
[Trypsin iontophoresis in spinal osteochondrosis]
Spotted Fever Group Rickettsiosis
Identification of Rickettsia rickettsii in formalin-fixed, paraffin-embedded tissues by immunofluorescence.
Squamous Cell Carcinoma of Head and Neck
Comparative study of the novel RGD motif-containing ITG?v?6 binding peptides SFLAP3 and SFITGv6 for diagnostic application in HNSCC.
Identification of a Novel ITG?v?6-Binding Peptide Using Protein Separation and Phage Display.
Intracellular co-localization of trypsin-2 and matrix metalloprotease-9: possible proteolytic cascade of trypsin-2, MMP-9 and enterokinase in carcinoma.
Tumor-Associated Trypsin Inhibitor (TATI) as a Biomarker of Poor Prognosis in Oropharyngeal Squamous Cell Carcinoma Irrespective of HPV Status.
Staphylococcal Infections
[Effect of trypsin on suppressor cell formation and function in localized staphylococcal infection]
[Effect of trypsin on the immune response in localized staphylococcal infection]
Starvation
A trypsin inhibitor trans-4-guanidinomethylcyclohexanecarboxylic acid 4-tert-butylphenyl ester suppresses the onset of DNA synthesis in Escherichia coli cells synchronized by phosphate starvation.
Digestive enzyme profiles reveal digestive capacity and potential energy sources in fed and starved spiny lobster (Jasus edwardsii) phyllosoma larvae.
Effect of starvation and refeeding on digestive enzyme activities in juvenile roach, Rutilus rutilus caspicus.
Effect of whey proteins, their oligopeptide hydrolysates and free amino acid mixtures on growth and nitrogen retention in fed and starved rats.
Influence of molting and starvation on the synthesis of proteolytic enzymes in the midgut gland of the white shrimp Penaeus vannamei.
Ontogenetic development of digestive enzymes and effect of starvation in miiuy croaker Miichthys miiuy larvae.
Seasonal variation in trypsin activity in juvenile Atlantic salmon upper and lower modal groups.
Selective regulation of trypsin gene expression by calcium and by glucose starvation in a rat exocrine pancreas cell line.
Structural refinement of insecticidal plant proteinase inhibitors from Nicotiana alata.
Surface exposure of glycosaminoglycans in resting, growing and virus transformed 3T3 cells.
The effect of feeding on the secretion of pepsin, trypsin and chymotrypsin in the Atlantic salmon,Salmo salar L.
The effects of starvation on digestive tract function and structure in juvenile southern catfish (Silurus meridionalis Chen).
[Effects of starvation and re-feeding on survival rate, growth and digestive enzyme activities of juvenile Sepia pharaonis.]
[Effects of starvation on digestive enzyme activities of Monopterus albus]
[Oxidative phosphorylation and the activity of the polyenzyme systems of rat liver mitochondrial membranes in starvation]
Steatorrhea
A follow-up study of annular pancreas in infants and children.
Calcium-ATPase activity in cystic fibrosis erythrocyte membranes: decreased activity in patients with pancreatic insufficiency.
Can plasma human pancreatic polypeptide be used to detect diseases of the exocrine pancreas?
Comparative diagnostic accuracy of four tubeless pancreatic function tests in chronic pancreatitis.
Comparison of ochratoxin, aflatoxin, and T-2 toxin for their effects on selected parameters related to digestion and evidence for specific metabolism of carotenoids in chickens.
Critical examination of therapeutic efficacy of a pH-sensitive enteric-coated pancreatic enzyme preparation in treatment of exocrine pancreatic insufficiency secondary to cystic fibrosis.
Effect of whey proteins, their oligopeptide hydrolysates and free amino acid mixtures on growth and nitrogen retention in fed and starved rats.
Enterokinase and trypsin activities in pancreatic insufficiency and diseases of the small intestine.
Exocrine pancreatic insufficiency after allogeneic bone marrow transplantation.
Fat digestion and exocrine pancreatic function in primary biliary cirrhosis.
Plasma immunoreactive pancreatic cationic trypsinogen in cystic fibrosis: a sensitive indicator of exocrine pancreatic dysfunction.
The noninvasive biochemical diagnosis of gastrointestinal disease, with special reference to children.
[Echostructure of the pancreas. Comparison with exocrine secretory activity of the pancreas in patients with diabetes mellitus]
[Evaluation of exocrine pancreatic function by the haptocorrin degradation test of the duodenal fluid collected by endoscopy]
[New trends in the treatment of exocrine pancreas deficiency]
steroid 21-monooxygenase deficiency
[Screening for hereditary diseases. What other screening?]
Stomach Diseases
Tumor-associated trypsin inhibitor (TATI) in benign and malignant gastric disease.
[On the treatment of pre- and postoperative pancreatic insufficiency with trypsin inhibitors in patients with gallbladder and stomach diseases.]
Stomach Neoplasms
Analysis of Cysteine Glutathionylation in Hemoglobin of Gastric Cancer Patients using Nanoflow Liquid Chromatography Triple-Stage Mass Spectrometry.
Cbl-b accelerates trypsin-induced cell detachment through ubiquitination and degradation of proline-rich tyrosine kinase 2.
Comparison of the prognostic value of a panel of tissue tumor markers and established clinicopathological factors in patients with gastric cancer.
Effects of endoscopic submucosal dissection on post-operative early treatment effectiveness and serum TAT-2 and GP73 expression levels in patients with early gastric cancer.
Effects of super-extended paraaortic lymphadenectomy (PAL) on biological responses in totally gastrectomized patients with T3 or T4 gastric cancer.
Enterolobium contortisiliquum trypsin inhibitor (EcTI), a plant proteinase inhibitor, decreases in vitro cell adhesion and invasion by inhibition of Src protein-focal adhesion kinase (FAK) signaling pathways.
Expression of trypsin in human cancer cell lines and cancer tissues and its tight binding to soluble form of Alzheimer amyloid precursor protein in culture.
High tissue expression of tumour-associated trypsin inhibitor (TATI) associates with a more favourable prognosis in gastric cancer.
Marked increase of trypsin(ogen) in serum of linitis plastica (gastric cancer, borrmann 4) patients.
Measurement of urinary trypsin inhibitor in urine, plasma and cancer tissues of patients with stomach cancer.
Production of trypsins by human gastric cancer cells correlates with their malignant phenotype.
Prophylactic administration of urinary trypsin inhibitor prevents postoperative hyperamylasemia after R2 gastrectomy in patients with gastric cancer. A prospective randomized trial.
Protease-activated receptor-2 induces expression of vascular endothelial growth factor and cyclooxygenase-2 via the mitogen-activated protein kinase pathway in gastric cancer cells.
Significance of the measurement of serum trypsin in patients surgically treated for gastric cancer.
Stimulation of cellular growth and adhesion to fibronectin and vitronectin in culture and tumorigenicity in nude mice by overexpression of trypsinogen in human gastric cancer cells.
The prevalence of pancreatic acinar differentiation in gastric adenocarcinoma: report of a case and immunohistochemical study of 111 additional cases.
The relationship between serum tumor-associated trypsin inhibitor levels and clinicopathological parameters in patients with gastric cancer.
Trypsinogen expression and early detection for peritoneal dissemination in gastric cancer.
Tumor-associated trypsin inhibitor (TATI) and tumor-associated trypsin-2 (TAT-2) predict outcomes in gastric cancer.
Tumor-associated trypsin inhibitor (TATI) in benign and malignant gastric disease.
[5-FU concentration in the tissue of gastric cancer, and evaluation of cancer chemotherapy with angiotensin-II]
[Study of plasminogen activator and trypsin inhibitor in gastric cancer, ulcer and experimental tumor.]
Stomach Ulcer
Protease inhibitors from ripened and unripened bananas.
Subarachnoid Hemorrhage
Protective effects of urinary trypsin inhibitor on vascular permeability following subarachnoid hemorrhage in a rat model.
Synovitis
Rheumatoid-like synovitis in rabbits by intra-articular administration of alpha 2-macroglobulin . trypsin complexes and alkylamine-treated alpha 2-macroglobulin.
Trypsin-2 degrades human type II collagen and is expressed and activated in mesenchymally transformed rheumatoid arthritis synovitis tissue.
Tenosynovitis
Chymotrypsin and trypsin sensitivities of avian reoviruses.
Teratocarcinoma
Biochemical properties of the high-molecular-weight glycopeptides released from the cell surface of human teratocarcinoma cells.
Teratocarcinoma cell adhesion: identification of a cell-surface protein involved in calcium-dependent cell aggregation.
Testicular Neoplasms
Cytogenetic evidence for premeiotic transformation of human testicular cancers.
Nonrandom abnormalities in chromosome 1 in human testicular cancers.
Tetanus
Botulinum neurotoxin type E fragmented with endoproteinase Lys-C reveals the site trypsin nicks and homology with tetanus neurotoxin.
Enzymatic hydrolysis of tetanus toxin by intrinsic and extrinsic proteases. Characterization of the fragments by monoclonal antibodies.
THE INFLUENCE OF TESTICLE EXTRACT ON THE INTRADERMAL SPREAD OF INJECTED FLUIDS AND PARTICLES.
[Application of theories on extraction of endocellular tetanus toxin. II. Effect of trypsin.]
Thrombasthenia
Platelet shape change: induction by trypsin and release of an acidic macroglycopeptide from washed human platelets and from those of three cases of Glanzmann's thrombasthenia.
Studies of the origin of platelet-associated fibrinogen.
Thromboembolism
Parenteral trypsin therapy for thrombophlebitis, thromboembolism, and chronic venous occlusion of the lower extremities: results in thirty-two cases at Brooke Army Hospital.
[Experimental research on the problem of serum protein changes caused by trypsin in the field of thromboembolism therapy.]
Thrombophilia
Pancreas graft thrombosis: is there a role for trypsin.
The risk of a first and a recurrent venous thrombosis associated with an elevated D-dimer level and an elevated thrombin potential: results of the THE-VTE study.
Thrombophlebitis
A clinical evaluation of intramuscular trypsin in the treatment of acute thrombophlebitis.
A clinical evaluation of parenteral trypsin in thrombophlebitis.
Clinical evaluation of trypsin in treatment of thrombophlebitis and sequelae, and hematomas after surgery of veins.
Intramuscular trypsin in the treatment of acute thrombophlebitis.
Intramuscular trypsin in the treatment of chronic thrombophlebitis.
Intramuscular trypsin in treatment of acute thrombophlebitis.
Parenteral trypsin therapy for thrombophlebitis, thromboembolism, and chronic venous occlusion of the lower extremities: results in thirty-two cases at Brooke Army Hospital.
The therapeutic effectiveness of trypsin in the treatment of thrombophlebitis.
Trypsin given intramuscularly in chronic, recurrent thrombophlebitis.
Trypsin intramuscularly in 129 cases of thrombophlebitis.
[Intramuscular administration of combined trypsin and chymotrypsin in therapy of thrombophlebitis of obstetric and gynecological origin.]
[Therapeutic possibilities of trypsin. I. Effects of intramuscular trypsin in thrombophlebitis and phlebothrombosis; clinical research.]
[Treatment of wounds, thrombophlebitis and lymphostasis by trypsin electrophoresis]
[Use of crystalline trypsin in the therapy of thrombophlebitis.]
[Use of trypsin in thrombophlebitis.]
Thrombosis
3D-QSAR CoMFA studies on trypsin-like serine protease inhibitors: a comparative selectivity analysis.
A novel fibrin(ogen)olytic trypsin-like protease from Chinese oak silkworm (Antheraea pernyi): purification and characterization.
Aptamer-peptide conjugates as a new strategy to modulate human ?-thrombin binding affinity.
Characterisation of a novel series of aprotinin-derived anticoagulants. II. Comparative antithrombotic effects on primary thrombus formation in vivo.
Degradation and liquefaction effect of streptokinase-Streptodornase and stabilized trypsin on necroses, crusts of fibrinoid, purulent exudate and clotted blood from leg ulcers.
Design and synthesis of isoxazoline derivatives as factor Xa inhibitors. 2.
Design, synthesis, and biological evaluation of potent and selective amidino bicyclic factor Xa inhibitors.
Improving the understanding of plasma kallikrein contribution to arterial thrombus formation using two plant protease inhibitors.
L-374,087, an efficacious, orally bioavailable, pyridinone acetamide thrombin inhibitor.
Nonpeptide factor Xa inhibitors: I. Studies with SF303 and SK549, a new class of potent antithrombotics.
Pancreas graft thrombosis: is there a role for trypsin.
Platelet-targeting thiol reduction sensor detects thiol isomerase activity on activated platelets in mouse and human blood under flow.
Post-operative thrombosis of the aorta following coarctectomy; report of a case treated with intravenous trypsin.
Potent and selective bicyclic lactam inhibitors of thrombin. Part 4: transition state inhibitors.
Preparation and properties of polyethylene glycol-trypsin adducts.
Protease-activated receptor 2 signaling in inflammation.
Protease-activated receptor 4: a critical participator in inflammatory response.
Reducing effect of 3,4',5-trihydroxystibene-3-beta-mono-D-glucoside on arterial thrombosis induced by vascular endothelial injury.
Retrograde trypsin instillation into the renal pelvis for the dissolution of obstructive blood clots.
The risk of a first and a recurrent venous thrombosis associated with an elevated D-dimer level and an elevated thrombin potential: results of the THE-VTE study.
Thrombosis (infarction) induced by kappa-carrageenin in rat tail: inhibition during adjuvant arthritis.
[Experimental thrombosis and its prevention with a trypsin inhibitor.]
[Histological studies of occlusion of retinal veins. I. Pathogenesis of venous thrombosis as revealed by trypsin digestion method]
Thymoma
Structural similarities between the mammalian beta-adrenergic and reovirus type 3 receptors.
Vascular architecture as a diagnostic marker for differentiation of World Health Organization thymoma subtypes and thymic carcinoma.
Thyroid Neoplasms
Molecular profiles of thyroid cancer subtypes: Classification based on features of tissue revealed by mass spectrometry imaging.
Thyrotoxicosis
[Study of peptide composition in serum albumin in patients with thyroid gland dysfunction]
Tick Infestations
Protective immunity against tick infestation in cattle vaccinated with recombinant trypsin inhibitor of Rhipicephalus microplus.
Tongue Neoplasms
Sporamin induce apoptosis in human tongue carcinoma cells by down-regulating Akt/GSK-3 signaling.
Tonsillitis
Organotypic (raft) culture of biopsy-derived upper respiratory epithelium.
Toxemia
[Effect of pancreatic kallikrein and trypsin inhibitors on the course of postischemic toxemia]
triacylglycerol lipase deficiency
The beta very low density lipoprotein present in hepatic lipase deficiency competitively inhibits low density lipoprotein binding to fibroblasts and stimulates fibroblast acyl-CoA:cholesterol acyltransferase.
Trichinellosis
Screening and characterization of early diagnostic antigens in excretory-secretory proteins from Trichinella spiralis intestinal infective larvae by immunoproteomics.
Trisomy 18 Syndrome
Trisomy 18, cystic fibrosis, and blood immunoreactive trypsin.
trypsin deficiency
Th-17 cells infiltrate the liver in human biliary atresia and are related to surgical outcome.
[External respiratory function in patients with primary pulmonary emphysema etiologically related to alpha 1-antitrypsin deficiency]
[Malabsorption and developmental retardation due to secondary trypsin deficiency]
[Recurrent pneumothorax: its association with alpha-1 trypsin deficiency.]
[Trypsin deficiency in diabetes mellitus of children and adolescents (author's transl)]
Tuberculosis
"1984": What Orwell could not predict. Proteomic analysis of his scripts.
Antigenic epitopes on Mycobacterium tuberculosis recognized by antibodies in tuberculosis and mouse antisera.
Comparison of three methods for the determination of serum alpha-1-antitrypsin in patients with pulmonary diseases.
Effect of trypsin and ribonuclease on the immunogenic activity of ribosomes and ribonucleic acid isolated from Mycobacterium tuberculosis.
Enzymatic débridement; particular reference to trypsin and desoxyribonuclease in the control of cough and sputum associated with tuberculosis.
Isolation of tuberculin peptides from tuberculin purified protein derivative (PPD).
Proteomic characterisation of bovine and avian purified protein derivatives and identification of specific antigens for serodiagnosis of bovine tuberculosis.
Surface alteration studies of Mycobacterium tuberculosis with trypsin.
Tuberculosis treated by Trypsin.
[Effects of trypsin and the products of trypsinization of the liver, lung and spleen on the sensitivity of Mycobacterium tuberculosis to chemotherapeutic substances]
[Report on possible uses of pure trypsin in tuberculosis therapy.]
Tuberculosis, Lymph Node
The use of trypsin in the therapy of tuberculous lymphadenitis and tuberculous fistulae.
Tuberculosis, Meningeal
A case report of miliary tuberculosis and tuberculous meningitis treated with trypsin and antibiotics: one year follow-up.
Tuberculosis, Miliary
A case report of miliary tuberculosis and tuberculous meningitis treated with trypsin and antibiotics: one year follow-up.
Tuberculosis, Pleural
[The clinical value of determining the general antitrypsin activity of the blood and exudate in tuberculous pleurisy]
Tuberculosis, Pulmonary
[Clinical study of a group of pulmonary tuberculosis patients treated with trypsin aerosol; preventive note.]
[Diagnostic value of using a 2.5 per cent solution of trypsin in pulmonary tuberculosis and chronic pneumonia in combination with bronchial asthma]
[On the parenteral use of trypsin in therapy of pulmonary tuberculosis.]
Tumor Virus Infections
Further studies on surface antigen of Shope papilloma cells: trypsin sensitivity.
INDUCTION OF TUMORS IN DOMESTIC RABBITS WITH NUCLEIC ACID PREPARATIONS FROM PARTIALLY PURIFIED SHOPE PAPILLOMA VIRUS AND FROM EXTRACTS OF THE PAPILLOMAS OF DOMESTIC AND COTTONTAIL RABBITS.
Turner Syndrome
Mosaic Turner syndrome: cytogenetics versus FISH.
Typhoid Fever
[Use of skim milk treated with peptin and trypsin as a culture medium for typhoid and paratyphoid B bacteria; a contribution on the use of the Wilson-Blair medium.]
Typhus, Epidemic Louse-Borne
Partial purification and characterization of the major species-specific protein antigens of Rickettsia typhi and Rickettsia prowazekii identified by rocket immunoelectrophoresis.
Upper Extremity Deep Vein Thrombosis
[Trypsin electrophoresis in the treatment of Paget-Schroetter syndrome]
Ureteral Obstruction
Ulinastatin attenuates renal interstitial inflammation and inhibits fibrosis progression in rats under unilateral ureteral obstruction.
Ulinastatin inhibits unilateral ureteral obstruction-induced renal interstitial fibrosis in rats via transforming growth factor ? (TGF-?)/Smad signalling pathways.
Urinary Bladder Diseases
[Experimental investigations on trypsin treatment of bladder diseases.]
Urinary Bladder Neoplasms
Angiotensin-II combined intra-arterial chemotherapy for locally advanced bladder cancer: a case series study at a single institution.
Differential expression of trypsinogen and tumor-associated trypsin inhibitor (TATI) in bladder cancer.
Evaluation of urine tumor-associated trypsin inhibitor, CYFRA 21-1, and urinary bladder cancer antigen for detection of high-grade bladder carcinoma.
Optimizing Orthotopic Bladder Tumor Implantation in a Syngeneic Mouse Model.
Pancreatic secretory trypsin inhibitor causes autocrine-mediated migration and invasion in bladder cancer and phosphorylates the EGF receptor, Akt2 and Akt3, and ERK1 and ERK2.
Prognostic value of the combined expression of tumor-associated trypsin inhibitor (TATI) and p53 in patients with bladder cancer undergoing radical cystectomy.
Specific sequences of fibronectin activate the protein kinase C signal transduction pathway in invasive bladder cancer.
The antitumor effect of the novel cancer-specific adenovirus Ad-VEGFR on bladder cancer in vitro and in vivo.
Tumor-associated trypsin inhibitor as a prognostic factor during follow-up of bladder cancer.
Urinary Tract Infections
The clinical effect of proteolytic enzyme containing bromelain and trypsin on urinary tract infection evaluated by double blind method.
The use of trypsin in urinary tract infections.
Urinary trypsin levels observed in pancreas transplant patients with duodenocystostomies promote in vitro fibrinolysis and in vivo bacterial adherence to urothelial surfaces.
[The treatment of urinary tract infection following transurethral prostatic resection by use of trypure solution.]
Urticaria
[Chronic urticaria and serum iron]
Uterine Cervical Neoplasms
Alpha 1-antitrypsin: a possible tool for diagnosis of cervical cancer.
Characterization of the anti-cancer-cell parasporal proteins of a Bacillus thuringiensis isolate.
Effects of the Medicago scutellata trypsin inhibitor (MsTI) on cisplatin-induced cytotoxicity in human breast and cervical cancer cells.
Protease-activated receptor-2 (PAR-2) in cervical cancer proliferation.
Purification and identification of novel cytotoxic oligopeptides from soft coral Sarcophyton glaucum.
Squamous cell carcinoma antigen, tumor associated trypsin inhibitor and tissue polypeptide specific antigen in follow up of stage III cervical cancer.
Squamous cell carcinoma antigen, tumor-associated trypsin inhibitor, and carcinoembryonic antigen for monitoring cervical cancer.
[Primary effect of preoperative intra-arterial infusion chemotherapy in cervical cancer]
[Radioimmunologic determination of gastrin, insulin, C-peptide, glucagon and trypsin in the combined radiotherapy of cervix cancer]
Vaccinia
Domain structure of vaccinia DNA ligase.
Enhancement of vaccinia virus plaque formation by trypsin.
Functional domains of vaccinia virus mRNA capping enzyme. Analysis by limited tryptic digestion.
Mechanism of inhibition of vaccinia DNA topoisomerase by novobiocin and coumermycin.
Modification of vaccinia virus penetration proteins analyzed by monoclonal antibodies.
Phosphorylation in vivo of a vaccinia-virus structural protein found associated with the ribosomes from infected cells.
[Effects of intramuscular trypsin on the course of experimental infection by vaccinia virus in rabbits.]
Vascular System Injuries
DIC secondary to acute pancreatitis.
Pulmonary vascular injury in pancreatitis: evidence for a major role played by pancreatic elastase.
Roscovitine attenuates intimal hyperplasia via inhibiting NF-?B and STAT3 activation induced by TNF-? in vascular smooth muscle cells.
Structure and interaction modes of thrombin.
The structure of thrombin: a janus-headed proteinase.
Vasculitis
Suppression of superantigen-induced lung injury and vasculitis by preadministration of human urinary trypsin inhibitor.
Venous Thromboembolism
[New antitoagulants]
Venous Thrombosis
Treatment of phlebothrombosis and its sequelae with intra-arterial trypsin.
Trypsin and thrombin induced venous thrombosis and its prevention with dicumarol, 3,3' methylenebis (4 hydroxycoumarin).
Trypsin in the treatment of deep venous thrombosis.
Trypsin in the treatment of venous thrombosis.
[Histological studies of occlusion of retinal veins. I. Pathogenesis of venous thrombosis as revealed by trypsin digestion method]
[Therapeutic possibilities of trypsin. I. Effects of intramuscular trypsin in thrombophlebitis and phlebothrombosis; clinical research.]
[Treatment of phlebothrombosis with intra-arterial trypsin.]
[Trypsin in the treatment of retinal venous thrombosis.]
Ventricular Premature Complexes
Relationship between hypertensive left ventricular hypertrophy, neurohormonal factors and ventricular arrhythmias in very old patients.
[Study on the relation between hypertensive left ventricular hypertrophy in very old people with neurohormonal factors and ventricular arrhythmias]
Vesicular Stomatitis
Enhanced growth and plaquing of rabies virus in static chick embryo cell culture.
Inhibition of Sindbis virus maturation after treatment of infected cells with trypsin.
pH-dependent hemolysis and cell fusion of rhabdoviruses.
Production of interferon by bovine peripheral blood monocytes infected with bovid herpesvirus 2.
The structure of vesicular stomatitis virus membrane. A phosphorus nuclear magnetic resonance approach.
Trypsin treatment of bovine ova after in vitro exposure to vesicular stomatitis virus.
[Hemagglutinating activity of various viruses on trypsinized erythrocytes]
Viremia
Structure-function relationships and mode of replication of animal rhabdoviruses.
Virus Diseases
Clinical utility of a rapid test for uristatin.
Detection of viral infection by immunofluorescence in formalin-fixed tissues, pretreated with trypsin.
Development of a rapid and sensitive quantitative assay for rotavirus based on flow cytometry.
Development of mouse monoclonal antibody for detecting hemagglutinin of avian influenza A(H7N9) virus and preventing virus infection.
Ectopic trypsin in the myocardium promotes dilated cardiomyopathy after influenza A virus infection.
Effect of mosquito midgut trypsin activity on dengue-2 virus infection and dissemination in Aedes aegypti.
Expression of the pancreatic secretory trypsin inhibitor gene in the liver infected with hepatitis B virus.
Identification of ectopic anionic trypsin I in rat lungs potentiating pneumotropic virus infectivity and increased enzyme level after virus infection.
Inactivation of HIV-1 by trypsin and its use in demonstrating specific virus infection of cells.
Infection enhancement of influenza A NWS virus in primary murine macrophages by anti-hemagglutinin monoclonal antibody.
Influenza virus-cytokine-protease cycle in the pathogenesis of vascular hyperpermeability in severe influenza.
Inhibition of Sindbis virus maturation after treatment of infected cells with trypsin.
Membrane receptors for interferon.
Pretreatment with protease is a useful experimental strategy for enhancing adenovirus-mediated cancer gene therapy.
Proteins induced in tissue culture by four isolates of Theiler's murine encephalomyelitis virus.
Receptor-bound porcine epidemic diarrhea virus spike protein cleaved by trypsin induces membrane fusion.
Role of trypsin in the replication of Avian metapneumovirus subtype C (strain MN-2a) and its entry into the Vero cells.
Sendai virus infection up-regulates trypsin I and matrix metalloproteinase-9, triggering viral multiplication and matrix degradation in rat lungs and lung L2 cells.
Study of cell surface antigens induced by herpes simplex virus. Note II. Some properties of the antigens.
The vaccinia virus F1L protein interacts with the proapoptotic protein Bak and inhibits Bak activation.
Trypsin promotes efficient influenza vaccine production in MDCK cells by interfering with the antiviral host response.
Urinary trypsin inhibitory activity for the diagnosis of bacterial infection: a prospective study in 690 patients.
Vitamin E Deficiency
[The effect of vitamin E deficiency on enzyme activity and the status of the membrane fraction of rat liver microsomes]
Vitiligo
A randomized pilot study to compare hair follicle cell suspensions prepared using trypsin alone versus trypsin in combination with collagenase type-I for transplantation in vitiligo.
Waldenstrom Macroglobulinemia
Primary structure of human J chain: isolation and characterization of tryptic and chymotryptic peptides of human J chain.
Warts
Parenzyme injection for plantar warts; a preliminary report.
Wheat Hypersensitivity
Nonceliac Gluten and Wheat Sensitivity.
Reduction of Allergenic Potential in Bread Wheat RNAi Transgenic Lines Silenced for CM3, CM16 and 0.28ATI Genes.
Whooping Cough
Activation mechanism of Gi and Go by reactive oxygen species.
Activation of human colon mast cells through proteinase activated receptor-2.
Adenylate cyclase toxins from Bacillus anthracis and Bordetella pertussis. Different processes for interaction with and entry into target cells.
Cooperative phenomena in binding and activation of Bordetella pertussis adenylate cyclase by calmodulin.
Dissociation of catalytic and invasive activities of Bordetella pertussis adenylate cyclase.
Effect of pertussis toxin and herbimycin A on proteinase-activated receptor 2-mediated cyclooxygenase 2 expression in Helicobacter pylori-infected gastric epithelial AGS cells.
Endogenous trypsin receptors in Xenopus oocytes: linkage to internal calcium stores.
Extracytoplasmic adenylate cyclase of Bordetella pertussis.
G protein beta 5 subunit interactions with alpha subunits and effectors.
Human leukocyte elastase induces keratinocyte proliferation by epidermal growth factor receptor activation.
Interaction of Bordetella pertussis adenylate cyclase with calmodulin. Identification of two separated calmodulin-binding domains.
Newly secreted adenylate cyclase toxin is responsible for intoxication of target cells by Bordetella pertussis.
Potentiation of cyclic adenosine monophosphate production by thrombin in the human erythroleukemia cell line, HEL.
Protease treatment of pertussis toxin identifies the preferential cleavage of the S1 subunit.
Receptor and G protein-mediated responses to thrombin in HEL cells.
Seminal fluid factor increases the resistance of the tight junctional complex of cultured human cervical epithelium CaSki cells.
Spurious protein activators of Bordetella pertussis adenylate cyclase.
Structural flexibility of the calmodulin-binding locus in Bordetella pertussis adenylate cyclase. Reconstitution of catalytically active species from fragments or inactive forms of the enzyme.
The effects of basic pancreatic trypsin inhibitor (BPTI) incorporated in Freund's complete adjuvant and in Freund's incomplete adjuvant containing Bordetella pertussis organisms (Per). Suppressive effect on cell mediated response to purified protein derivative and competing effect on antibody formation to Per in guinea pigs.
Treatment of human platelets with trypsin, thrombin, or collagen inhibits the pertussis toxin-induced ADP-ribosylation of a 41-kDa protein.
Trypsin, an adjunct in treating pertussis; a report of two cases.
[Localization of segments in the Gs protein interacting with adenylate cyclase using a Gs/G0-chimera]
Wilms Tumor
Immunohistochemistry for the differentiation of peritoneal disseminated carcinoma of unknown origin.
Wound Infection
Evaluation of Mannosidase and Trypsin Enzymes Effects on Biofilm Production of Pseudomonas aeruginosa Isolated from Burn Wound Infections.
Yellow Fever
A temporal profile of the endocrine control of trypsin synthesis in the yellow fever mosquito, Aedes aegypti.
Enhanced activity of an insecticidal protein, trypsin modulating oostatic factor (TMOF), through conjugation with aliphatic polyethylene glycol.
Increase in the size of the amino acid pool is sufficient to activate translation of early trypsin mRNA in Aedes aegypti midgut.
Polyamines, and effects from reducing their synthesis during egg development in the yellow fever mosquito, Aedes aegypti.
[Direct immunofluorescence demonstration of yellow fever antigens in hepatic tissue pre-treated with trypsin]
Zellweger Syndrome
Properties of the enzymes catalyzing the biosynthesis of lysophosphatidate and its ether analog in cultured fibroblasts from Zellweger syndrome patients and normal controls.