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Information on EC 3.4.24.3 - microbial collagenase

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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.3 microbial collagenase
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The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Reaction Schemes
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Digestion of native collagen in the triple helical region at -/-Gly bonds. With synthetic peptides, a preference is shown for Gly at P3 and P1', Pro and Ala at P2 and P2', and hydroxyproline, Ala or Arg at P3'
Synonyms
bacterial collagenase, collagenase clostridium histolyticum, type i collagenase, collagenase i, clostridial collagenase, clostridium histolyticum collagenase, type ii collagenase, clostridiopeptidase a, collagenase g, collagenase h, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
Digestion of native collagen in the triple helical region at -/-Gly bonds. With synthetic peptides, a preference is shown for Gly at P3 and P1', Pro and Ala at P2 and P2', and hydroxyproline, Ala or Arg at P3'
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