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Information on EC 4.2.3.153 - (5-formylfuran-3-yl)methyl phosphate synthase

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EC Tree
     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.153 (5-formylfuran-3-yl)methyl phosphate synthase
IUBMB Comments
The enzyme catalyses the reaction in the direction of producing (5-formylfuran-3-yl)methyl phosphate, an intermediate in the biosynthesis of methanofuran. The sequence of events starts with the removal of a phosphate group, followed by aldol condensation and cyclization. Methanofuran is a carbon-carrier cofactor involved in the first step of the methanogenic reduction of carbon dioxide by methanogenic archaea.
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The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Synonyms
mj1099, 4-(hydroxymethyl)-2-furancarboxaldehyde-phosphate synthase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 D-glyceraldehyde 3-phosphate = (5-formylfuran-3-yl)methyl phosphate + phosphate + 2 H2O
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
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