Disease on EC 6.3.1.1 - aspartate-ammonia ligase
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Adenocarcinoma
Asparagine Synthetase Expression and Phase I Study With L-Asparaginase Encapsulated in Red Blood Cells in Patients With Pancreatic Adenocarcinoma.
arylsulfatase (type i) deficiency
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
aspartate-ammonia ligase deficiency
A novel compound heterozygous missense mutation in ASNS broadens the spectrum of asparagine synthetase deficiency.
aspartate-ammonia ligase deficiency
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
aspartate-ammonia ligase deficiency
Asparagine Synthetase Deficiency causes reduced proliferation of cells under conditions of limited asparagine.
aspartate-ammonia ligase deficiency
Asparagine synthetase deficiency detected by whole exome sequencing causes congenital microcephaly, epileptic encephalopathy and psychomotor delay.
aspartate-ammonia ligase deficiency
Asparagine Synthetase Deficiency with Intracranial Hemorrhage Can Mimic Molybdenum Cofactor Deficiency.
aspartate-ammonia ligase deficiency
Asparagine Synthetase deficiency-report of a novel mutation and review of literature.
aspartate-ammonia ligase deficiency
Asparagine synthetase deficiency: A novel case with an unusual molecular mechanism.
aspartate-ammonia ligase deficiency
Asparagine Synthetase Deficiency: New Inborn Errors of Metabolism.
aspartate-ammonia ligase deficiency
Characterization of a novel variant in siblings with Asparagine Synthetase Deficiency.
aspartate-ammonia ligase deficiency
Clinical outcomes of two patients with a novel pathogenic variant in ASNS: response to asparagine supplementation and review of the literature.
aspartate-ammonia ligase deficiency
Clinical whole exome sequencing from dried blood spot identifies novel genetic defect underlying asparagine synthetase deficiency.
aspartate-ammonia ligase deficiency
Clinical, molecular, and biochemical delineation of asparagine synthetase deficiency in Saudi cohort.
aspartate-ammonia ligase deficiency
Congenital microcephaly with early onset epileptic encephalopathy caused by ASNS gene mutation: A case report.
aspartate-ammonia ligase deficiency
Cyst-Peritoneal Shunt for the Treatment of a Progressive Intracerebral Cyst Associated with ASNS Mutation: Case Report and Literature Review.
aspartate-ammonia ligase deficiency
Diaphragmatic Eventration in Sisters with Asparagine Synthetase Deficiency: A Novel Homozygous ASNS Mutation and Expanded Phenotype.
aspartate-ammonia ligase deficiency
Effects of A6E Mutation on Protein Expression and Supramolecular Assembly of Yeast Asparagine Synthetase.
aspartate-ammonia ligase deficiency
Epileptic encephalopathy with microcephaly in a patient with asparagine synthetase deficiency: a video-EEG report.
aspartate-ammonia ligase deficiency
Fetal MRI and ultrasound findings of a confirmed asparagine synthetase deficiency case.
aspartate-ammonia ligase deficiency
Generation of four induced pluripotent stem cell lines, GZWWTi001-A, GZWTZi001-A, GZWXYi001-A, and GZWXDi001-A, derived from peripheral blood mononuclear cells from a family with asparagine synthetase deficiency.
aspartate-ammonia ligase deficiency
Hyperekplexia, microcephaly and simplified gyral pattern caused by novel ASNS mutations, case report.
aspartate-ammonia ligase deficiency
In vitro functional analysis of four variants of human asparagine synthetase.
aspartate-ammonia ligase deficiency
Report of four novel variants in ASNS causing asparagine synthetase deficiency and review of literature.
aspartate-ammonia ligase deficiency
The first report of Japanese patients with asparagine synthetase deficiency.
aspartate-ammonia ligase deficiency
Worsening of Seizures After Asparagine Supplementation in a Child with Asparagine Synthetase Deficiency.
Brain Diseases
Asparagine synthetase deficiency detected by whole exome sequencing causes congenital microcephaly, epileptic encephalopathy and psychomotor delay.
Brain Diseases
Asparagine synthetase deficiency: A novel case with an unusual molecular mechanism.
Brain Diseases
Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy.
Brain Diseases
Diaphragmatic Eventration in Sisters with Asparagine Synthetase Deficiency: A Novel Homozygous ASNS Mutation and Expanded Phenotype.
Brain Diseases
Epileptic encephalopathy with microcephaly in a patient with asparagine synthetase deficiency: a video-EEG report.
Brain Edema
Asparagine Synthetase Deficiency with Intracranial Hemorrhage Can Mimic Molybdenum Cofactor Deficiency.
Breast Neoplasms
Down-Regulation of Asparagine Synthetase Induces Cell Cycle Arrest and Inhibits Cell Proliferation of Breast Cancer.
Breast Neoplasms
High Expression of Asparagine Synthetase Is Associated with Poor Prognosis of Breast Cancer in Chinese Population.
Breast Neoplasms
High-resolution crystal structure of human asparagine synthetase enables analysis of inhibitor binding and selectivity.
Carcinoma
Enhanced expression of asparagine synthetase under glucose-deprived conditions promotes esophageal squamous cell carcinoma development.
Carcinoma, Hepatocellular
Alignment of the Transcription Start Site Coincides with Increased Transcriptional Activity from the Human Asparagine Synthetase Gene Following Amino Acid Deprivation of HepG2 Cells.
Carcinoma, Hepatocellular
Asparagine synthetase is an independent predictor of surgical survival and a potential therapeutic target in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Hepatoblastoma: glutamine depletion hinders cell viability in the embryonal subtype but high GLUL expression is associated with better overall survival.
Carcinoma, Hepatocellular
Polymorphism in asparagine synthetase is associated with overall survival of hepatocellular carcinoma patients.
Carcinoma, Hepatocellular
Regulation of asparagine synthetase gene transcription by the basic region leucine zipper transcription factors ATF5 and CHOP.
Carcinoma, Non-Small-Cell Lung
Suppression of asparagine synthetase enhances the antitumor potency of ART and artemalogue SOMCL-14-221 in non-small cell lung cancer.
Carcinoma, Squamous Cell
Knockdown of asparagine synthetase by RNAi suppresses cell growth in human melanoma cells and epidermoid carcinoma cells.
Chordoma
Proteomics Analysis Identified ASNS as a Novel Biomarker for Predicting Recurrence of Skull Base Chordoma.
Colorectal Neoplasms
Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase.
Congenital Disorders of Glycosylation
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
A novel compound heterozygous missense mutation in ASNS broadens the spectrum of asparagine synthetase deficiency.
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Diaphragmatic Eventration
Diaphragmatic Eventration in Sisters with Asparagine Synthetase Deficiency: A Novel Homozygous ASNS Mutation and Expanded Phenotype.
Drug Resistant Epilepsy
Worsening of Seizures After Asparagine Supplementation in a Child with Asparagine Synthetase Deficiency.
Epilepsy
Asparagine Synthetase Deficiency causes reduced proliferation of cells under conditions of limited asparagine.
Esophageal Squamous Cell Carcinoma
Enhanced expression of asparagine synthetase under glucose-deprived conditions promotes esophageal squamous cell carcinoma development.
Glioblastoma
Elevated Asparagine Biosynthesis Drives Brain Tumor Stem Cell Metabolic Plasticity and Resistance to Oxidative Stress.
Glioma
Clinical aggressiveness of malignant gliomas is linked to augmented metabolism of amino acids.
Glioma
Metabolic plasticity of IDH1-mutant glioma cell lines is responsible for low sensitivity to glutaminase inhibition.
Glycogen Storage Disease
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Hepatoblastoma
Hepatoblastoma: glutamine depletion hinders cell viability in the embryonal subtype but high GLUL expression is associated with better overall survival.
Hyperekplexia
Hyperekplexia, microcephaly and simplified gyral pattern caused by novel ASNS mutations, case report.
Hyperglycinemia, Nonketotic
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Hypersensitivity
Polymorphisms of asparaginase pathway and asparaginase-related complications in children with acute lymphoblastic leukemia.
Hypophosphatasia
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Infections
Alterations in metabolic pathways in gastric epithelial cells infected with Helicobacter pylori.
Infections
Modulating plant primary amino acid metabolism as a necrotrophic virulence strategy: The immune-regulatory role of asparagine synthetase in Botrytis cinerea-tomato interaction.
Intellectual Disability
Asparagine Synthetase Deficiency causes reduced proliferation of cells under conditions of limited asparagine.
Intracranial Hemorrhages
Asparagine Synthetase Deficiency with Intracranial Hemorrhage Can Mimic Molybdenum Cofactor Deficiency.
Leukemia
A sulfoximine-based inhibitor of human asparagine synthetase kills l-asparaginase-resistant leukemia cells.
Leukemia
Amino acid control of asparagine synthetase: relation to asparaginase resistance in human leukemia cells.
Leukemia
Aminomalonic acid and its congeners as potential in vivo inhibitors of L-asparagine synthetase.
Leukemia
An inhibitor of human asparagine synthetase suppresses proliferation of an L-asparaginase-resistant leukemia cell line.
Leukemia
An investigation into the mechanism ofL-asparaginase resistance in L5178Y murine leukemia cells.
Leukemia
Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells.
Leukemia
Asparagine synthetase expression is associated with the sensitivity to asparaginase in extranodal natural killer/T-cell lymphoma in vivo and in vitro.
Leukemia
Association of allele-specific methylation of the ASNS gene with asparaginase sensitivity and prognosis in T-ALL.
Leukemia
ATF5 polymorphisms influence ATF function and response to treatment in children with childhood acute lymphoblastic leukemia.
Leukemia
Declined asparagine synthetase mRNA expression and enhanced sensitivity to asparaginase in HL-60 cells committed to monocytic differentiation.
Leukemia
Decrease in asparagine synthetase activity during cell differentiation of mouse and human leukemia cell lines.
Leukemia
Enzymatic and nutritional evidence for two-stage exression of the asparagine synthetase locus in L5178y murine leukemia mutants.
Leukemia
Evaluation of the asparagine synthetase level in leukemia cells by monoclonal antibodies.
Leukemia
Mass spectrometric quantification of asparagine synthetase in circulating leukemia cells from acute lymphoblastic leukemia patients.
Leukemia
Sequential high-dose ara-C and asparaginase versus high-dose ara-C alone in the treatment of patients with relapsed and refractory acute leukemias.
Leukemia
Triazolo[4,5-d]pyrimidines as Validated General Control Nonderepressible 2 (GCN2) Protein Kinase Inhibitors Reduce Growth of Leukemia Cells.
Leukemia, Myeloid
Decrease in asparagine synthetase activity during cell differentiation of mouse and human leukemia cell lines.
Leukemia, Myeloid, Acute
Red blood cell-encapsulated L-asparaginase: potential therapy of patients with asparagine synthetase deficient acute myeloid leukemia.
Liver Neoplasms, Experimental
Potential inhibitors of L-asparagine biosynthesis. 2. Chemistry and biological activity of beta-hydroxyaspartic acid and its derivatives.
Liver Neoplasms, Experimental
Potential inhibitors of L-asparagine biosynthesis. 5. Electrophilic amide analogues of (S)-2,3-diaminopropionic acid.
Liver Neoplasms, Experimental
Purification and properties of asparagine synthetase from rat liver.
Lung Neoplasms
Loss of asparagine synthetase suppresses the growth of human lung cancer cells by arresting cell cycle at G0/G1 phase.
Lung Neoplasms
Suppression of asparagine synthetase enhances the antitumor potency of ART and artemalogue SOMCL-14-221 in non-small cell lung cancer.
Lymphoma
Asparagine synthetase expression and its potential prognostic value in patients with NK/T cell lymphoma.
Lymphoma
Asparagine synthetase expression is associated with the sensitivity to asparaginase in extranodal natural killer/T-cell lymphoma in vivo and in vitro.
Lymphoma
Hypermethylation of CpG islands in the mouse asparagine synthetase gene: relationship to asparaginase sensitivity in lymphoma cells. Partial methylation in normal cells.
Lymphoma
L-asparaginyl-tRNA synthetase and L-asparagine synthetase activities of L-asparaginase-sensitive and -resistant forms of the mouse Gardner lymphoma 6C3HED.
Lymphoma
Some properties of L-asparagine synthetase of the L-asparaginase-resistant mouse lymphoma 6C3HED [proceedings]
Lymphoma
[Expression of asparagine synthetase in relapsed or refractory extranodal NK/T cell lymphoma].
Lysosomal Storage Diseases
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Melanoma
Knockdown of asparagine synthetase by RNAi suppresses cell growth in human melanoma cells and epidermoid carcinoma cells.
Metabolism, Inborn Errors
Asparagine Synthetase Deficiency: New Inborn Errors of Metabolism.
Microcephaly
A novel compound heterozygous missense mutation in ASNS broadens the spectrum of asparagine synthetase deficiency.
Microcephaly
Asparagine synthetase deficiency detected by whole exome sequencing causes congenital microcephaly, epileptic encephalopathy and psychomotor delay.
Microcephaly
Asparagine Synthetase Deficiency with Intracranial Hemorrhage Can Mimic Molybdenum Cofactor Deficiency.
Microcephaly
Asparagine synthetase deficiency: A novel case with an unusual molecular mechanism.
Microcephaly
Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy.
Microcephaly
Diaphragmatic Eventration in Sisters with Asparagine Synthetase Deficiency: A Novel Homozygous ASNS Mutation and Expanded Phenotype.
Microcephaly
Epileptic encephalopathy with microcephaly in a patient with asparagine synthetase deficiency: a video-EEG report.
Microcephaly
Hyperekplexia, microcephaly and simplified gyral pattern caused by novel ASNS mutations, case report.
Microcephaly
Novel Mutations in the Asparagine Synthetase Gene (ASNS) Associated With Microcephaly.
Microcephaly
Worsening of Seizures After Asparagine Supplementation in a Child with Asparagine Synthetase Deficiency.
Muscle Spasticity
Worsening of Seizures After Asparagine Supplementation in a Child with Asparagine Synthetase Deficiency.
Muscular Atrophy
Cystathionine gamma-Lyase-deficient mice require dietary cysteine to protect against acute lethal myopathy and oxidative injury.
Muscular Diseases
Progressive Degenerative Myopathy and Myosteatosis in ASNSD1-Deficient Mice.
Nasopharyngeal Carcinoma
Overexpression of Asparagine Synthetase and Matrix Metalloproteinase 19 Confers Cisplatin Sensitivity in Nasopharyngeal Carcinoma Cells.
Neoplasm Metastasis
Asparagine bioavailability governs metastasis in a model of breast cancer.
Neoplasm Metastasis
Asparagine Synthetase Expression and Phase I Study With L-Asparaginase Encapsulated in Red Blood Cells in Patients With Pancreatic Adenocarcinoma.
Neoplasms
Amino acids signatures of distance-related surgical margins of oral squamous cell carcinoma.
Neoplasms
Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction.
Neoplasms
Asparagine Depletion Potentiates the Cytotoxic Effect of Chemotherapy Against Brain Tumors.
Neoplasms
Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion.
Neoplasms
Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells.
Neoplasms
Asparagine synthetase expression and its potential prognostic value in patients with NK/T cell lymphoma.
Neoplasms
Asparagine Synthetase Expression and Phase I Study With L-Asparaginase Encapsulated in Red Blood Cells in Patients With Pancreatic Adenocarcinoma.
Neoplasms
Asparagine synthetase in normal and malignant tissues: correlation with tumor sensitivity to asparaginase.
Neoplasms
Asparagine Synthetase: Regulation by Cell Stress and Involvement in Tumor Biology.
Neoplasms
Canagliflozin Improves Liver Function in Rats by Upregulating Asparagine Synthetase.
Neoplasms
Consumption of meat containing ractopamine might enhance tumor growth through induction of asparagine synthetase.
Neoplasms
Discovery of why acute lymphoblastic leukaemia cells are killed by asparaginase: Adventures of a young post-doctoral student, Bertha K Madras.
Neoplasms
Down-Regulation of Asparagine Synthetase Induces Cell Cycle Arrest and Inhibits Cell Proliferation of Breast Cancer.
Neoplasms
Glutamine-dependent asparagine synthetase in fetal, adult and neoplastic rat tissues.
Neoplasms
High-resolution crystal structure of human asparagine synthetase enables analysis of inhibitor binding and selectivity.
Neoplasms
Incorporation of monoclonal antibodies into cells by osmotic permeabilization. Effect on cellular metabolism.
Neoplasms
Inhibition of GCN2 sensitizes ASNS-low cancer cells to asparaginase by disrupting the amino acid response.
Neoplasms
Interaction of the eucaryotic peptide chain initiation factor eIF-4A with the specific elements at the 5'-untranslated sequence of human asparagine synthetase mRNA.
Neoplasms
Knockdown of asparagine synthetase (ASNS) suppresses cell proliferation and inhibits tumor growth in gastric cancer cells.
Neoplasms
Knockdown of asparagine synthetase by RNAi suppresses cell growth in human melanoma cells and epidermoid carcinoma cells.
Neoplasms
Microarray analysis uncovers retinoid targets in human bronchial epithelial cells.
Neoplasms
Successful treatment with Erwinia L-asparaginase for recurrent natural killer/T cell lymphoma.
Neoplasms
The glutaminase activity of L-asparaginase is not required for anticancer activity against ASNS-negative cells.
Neoplasms
Translational reprogramming marks adaptation to asparagine restriction in cancer.
Ovarian Neoplasms
Asparagine Synthetase and Filamin A Have Different Roles in Ovarian Cancer.
Ovarian Neoplasms
Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells.
Ovarian Neoplasms
Asparagine synthetase is a predictive biomarker of L-asparaginase activity in ovarian cancer cell lines.
Ovarian Neoplasms
Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel.
Ovarian Neoplasms
Searching for pharmacogenomic markers: the synergy between omic and hypothesis-driven research.
Pancreatic Diseases
The role of asparagine synthetase on nutrient metabolism in pancreatic disease.
Pancreatic Neoplasms
Enhanced expression of asparagine synthetase under glucose-deprived conditions protects pancreatic cancer cells from apoptosis induced by glucose deprivation and cisplatin.
Pancreatitis
Polymorphisms of asparaginase pathway and asparaginase-related complications in children with acute lymphoblastic leukemia.
Paralysis
Cystathionine gamma-Lyase-deficient mice require dietary cysteine to protect against acute lethal myopathy and oxidative injury.
Peroxisomal Disorders
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Persistent Vegetative State
Worsening of Seizures After Asparagine Supplementation in a Child with Asparagine Synthetase Deficiency.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Asparagine synthetase (ASNS) gene polymorphism is associated with the outcome of childhood acute lymphoblastic leukemia by affecting early response to treatment.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Asparagine synthetase expression is linked with L-asparaginase resistance in TEL-AML1-negative but not TEL-AML1-positive pediatric acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Asparagine Synthetase in Cancer: Beyond Acute Lymphoblastic Leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Correlation between asparaginase sensitivity and asparagine synthetase protein content, but not mRNA, in acute lymphoblastic leukemia cell lines.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Efficient expression, purification, and characterization of C-terminally tagged, recombinant human asparagine synthetase.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Evaluation of the asparagine synthetase level in leukemia cells by monoclonal antibodies.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Functional analysis of a novel DNA polymorphism of a tandem repeated sequence in the asparagine synthetase gene in acute lymphoblastic leukemia cells.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Human asparagine synthetase associates with the mitotic spindle.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Hypomethylation and reactivation of the asparagine synthetase gene induced by L-asparaginase and ethyl methanesulfonate.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Mapping the aspartic acid binding site of Escherichia coli asparagine synthetase B using substrate analogs.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Mass spectrometric quantification of asparagine synthetase in circulating leukemia cells from acute lymphoblastic leukemia patients.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Mesenchymal cells regulate the response of acute lymphoblastic leukemia cells to asparaginase.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Methylation analysis of asparagine synthetase gene in acute lymphoblastic leukemia cells.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Up-regulation of asparagine synthetase expression is not linked to the clinical response L-asparaginase in pediatric acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
[Asparagine synthetase activity in pediatric acute lymphoblastic leukemia]
Precursor Cell Lymphoblastic Leukemia-Lymphoma
[Study of the correlation between the expression level of asparagine synthetase and the outcome of children with acute lymphocytic leukemia]
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Epigenetic Silencing Affects l-Asparaginase Sensitivity and Predicts Outcome in T-ALL.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
[Asparagine synthetase activity in pediatric acute lymphoblastic leukemia]
Prostatic Neoplasms
Integrative molecular profiling reveals asparagine synthetase is a target in castration-resistant prostate cancer.
pyruvate carboxylase deficiency
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Pyruvate Carboxylase Deficiency Disease
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
pyruvate dehydrogenase (nadp+) deficiency
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Pyruvate Dehydrogenase Complex Deficiency Disease
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Quadriplegia
A novel compound heterozygous missense mutation in ASNS broadens the spectrum of asparagine synthetase deficiency.
Quadriplegia
Worsening of Seizures After Asparagine Supplementation in a Child with Asparagine Synthetase Deficiency.
Rectal Neoplasms
Deficiency in asparagine synthetase expression in rectal cancers receiving concurrent chemoradiotherapy: negative prognostic impact and therapeutic relevance.
Sarcoma
Functional genomic screening reveals asparagine dependence as a metabolic vulnerability in sarcoma.
Sarcoma
Isolation of human cDNAs for asparagine synthetase and expression in Jensen rat sarcoma cells.
Sarcoma
Properties of asparagine synthetase in asparagine-independent variants of Jensen rat sarcoma cells induced by 5-azacytidine.
Seizures
A novel compound heterozygous missense mutation in ASNS broadens the spectrum of asparagine synthetase deficiency.
Seizures
Hyperekplexia, microcephaly and simplified gyral pattern caused by novel ASNS mutations, case report.
Seizures
Worsening of Seizures After Asparagine Supplementation in a Child with Asparagine Synthetase Deficiency.
Starvation
Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction.
Starvation
Asparagine metabolism and nitrogen distribution during protein degradation in sugar-starved maize root tips.
Starvation
Decrease in asparagine synthetase activity during cell differentiation of mouse and human leukemia cell lines.
Starvation
EVI1 triggers metabolic reprogramming associated with leukemogenesis and increases sensitivity to L-asparaginase.
Starvation
Expression of CsSEF1 gene encoding putative CCCH zinc finger protein is induced by defoliation and prolonged darkness in cucumber fruit.
Starvation
The synergism of 6-mercaptopurine plus cytosine arabinoside followed by PEG-asparaginase in human leukemia cell lines (CCRF/CEM/0 and (CCRF/CEM/ara-C/7A) is due to increased cellular apoptosis.
Starvation
TRB3 inhibits the transcriptional activation of stress-regulated genes by a negative feedback on the ATF4 pathway.
Stomach Neoplasms
Knockdown of asparagine synthetase (ASNS) suppresses cell proliferation and inhibits tumor growth in gastric cancer cells.
transaldolase deficiency
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
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