Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.282 extracted from

  • Barea, J.L.; Giles, N.H.
    Purification and characterization of quinate (shikimate) dehydrogenase, an enzyme in the inducible quinic acid catabolic pathway of Neurospora crassa (1978), Biochim. Biophys. Acta, 524, 1-14.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.37
-
L-quinate
-
Neurospora crassa
1.18
-
shikimate
-
Neurospora crassa

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
41000
-
1 * 41000 Neurospora crassa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Neurospora crassa catalyzes the first reaction in the inducible quinic acid catabolic pathway ?
-
?

Organism

Organism UniProt Comment Textmining
Neurospora crassa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Neurospora crassa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-quinate + NAD(P)+ bifunctional enzyme with a single binding site for both substrates quinate and shikimate, the velocity is approximately 3fold lower with quinate than with shikimate Neurospora crassa 3-dehydroquinate + NAD(P)H + H+
-
?
additional information catalyzes the first reaction in the inducible quinic acid catabolic pathway Neurospora crassa ?
-
?
shikimate + NAD(P)+ bifunctional enzyme with a single binding site for both substrates quinate and shikimate, the velocity is approximately 3fold higher with shikimate than with quinate Neurospora crassa 3-dehydroshikimate + NAD(P)H + H+
-
?

Subunits

Subunits Comment Organism
monomer 1 * 41000 Neurospora crassa

Temperature Stability [┬░C]

Temperature Stability Minimum [┬░C] Temperature Stability Maximum [┬░C] Comment Organism
additional information
-
the thermal stability of enzyme is greatly enhanced by low concentrations of quinate, shikimate, NADH or high ionic strength Neurospora crassa