Cloned (Comment) | Organism |
---|---|
- |
Ruditapes philippinarum |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
selenium | dependent on | Ruditapes philippinarum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione + H2O2 | Ruditapes philippinarum | - |
glutathione disulfide + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Ruditapes philippinarum | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adductor muscle | low expression | Ruditapes philippinarum | - |
gill | low expression | Ruditapes philippinarum | - |
hemocyte | low expression | Ruditapes philippinarum | - |
hepatopancreas | most abundantly expressed in hepatopancreas | Ruditapes philippinarum | - |
mantle | low expression | Ruditapes philippinarum | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione + H2O2 | - |
Ruditapes philippinarum | glutathione disulfide + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Se-GPx | - |
Ruditapes philippinarum |
selenium-dependent glutathione peroxidase | - |
Ruditapes philippinarum |
Organism | Comment | Expression |
---|---|---|
Ruditapes philippinarum | Vibrio challenge can significantly upregulate the mRNA expression of the enzyme, and the highest expression level (6.5fold) is detected at 24 h post infection with 6.5fold increase compared with that in the control group. Enzyme expression is significantly induced by 0.02 and 0.04 mg l-1 Cd (both 2.9fold after 24 h) and 0.01 and 0.02 mg l-1 Cu (2.7fold after 24 h and 1.6fold at 96 h, respectively). The mRNA expression is maximally induced (6.29fold) at 96 h post challenge with 0.05 mg l-1 benzo[a]pyrene | up |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is potentially involved in mediating the immune response and antioxidant defense | Ruditapes philippinarum |