Literature summary for 1.13.11.54 extracted from

Guo, T.; Zhang, X.; Li, Y.; Liu, C.; Wang, N.; Jiang, Q.; Wu, J.; Ma, F.; Liu, C.
Overexpression of MdARD4 accelerates fruit ripening and increases cold hardiness in tomato (2020), Int. J. Mol. Sci., 21, 6182 .

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Solanum lycopersicum cultivar Micro-Tom and in Nicotiana tabacum	Malus domestica

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Fe2+	dependent on	Malus domestica

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2	Malus domestica	-	4-(methylsulfanyl)-2-oxobutanoate + formate	-	?

Organism

Organism	UniProt	Comment	Textmining
Malus domestica	A0A481SQ81	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
fruit	-	Malus domestica	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2	-	Malus domestica	4-(methylsulfanyl)-2-oxobutanoate + formate	-	?

Synonyms

Synonyms	Comment	Organism
ARD4	-	Malus domestica

Expression

Organism	Comment	Expression
Malus domestica	the transcript level of isoform ARD4 is induced during apple fruit ripening and after apple plants are being treated with cold stress	up

General Information

General Information	Comment	Organism
physiological function	isoform ARD4 regulates the ethylene and carotenoid signaling pathway, increases ethylene and carotenoid concentrations, and accelerates fruit ripening. Furthermore, ARD4 increases the antioxidative ability and cold hardiness in tomato	Malus domestica

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Release 2023.1 (January 2023)