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Literature summary for 1.13.11.78 extracted from

  • Woersdoerfer, B.; Lingaraju, M.; Yennawar, N.H.; Boal, A.K.; Krebs, C.; Bollinger, J.M.; Pandelia, M.E.
    Organophosphonate-degrading PhnZ reveals an emerging family of HD domain mixed-valent diiron oxygenases (2013), Proc. Natl. Acad. Sci. USA, 110, 18874-18879.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells uncultured bacterium

Metals/Ions

Metals/Ions Comment Organism Structure
Iron the enzyme contains 1.2 Fe per monomer, contains a dinuclear iron cluster. The mixed-valent FeII/FeIII state is the catalytically active cofactor form uncultured bacterium

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(2-amino-1-hydroxyethyl)phosphonate + O2 uncultured bacterium
-
 glycine + phosphate
-
 ?
(2-amino-1-hydroxyethyl)phosphonate + O2 uncultured bacterium HF130 AEPn 1
-
 glycine + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
uncultured bacterium D0E8I5
-
-
uncultured bacterium HF130 AEPn 1 D0E8I5
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni2+-affinity chromatography uncultured bacterium

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2-amino-1-hydroxyethyl)phosphonate + O2
-
 uncultured bacterium glycine + phosphate
-
 ?
(2-amino-1-hydroxyethyl)phosphonate + O2
-
 uncultured bacterium HF130 AEPn 1 glycine + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
phnZ
-
 uncultured bacterium