Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
hanging drop vapour diffusion method | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
15330 | - |
3 * 15330, X-ray crystallography | Homo sapiens |
46000 | - |
X-ray crystallography | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
hypoxia-inducible factor L-proline + 2-oxoglutarate + O2 | Homo sapiens | - |
hypoxia inducible factor trans-4-hydroxy-L-proline + succinate + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA column chromatography and gel filtration | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
hypoxia-inducible factor L-proline + 2-oxoglutarate + O2 | - |
Homo sapiens | hypoxia inducible factor trans-4-hydroxy-L-proline + succinate + CO2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
homotrimer | 3 * 15330, X-ray crystallography | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
hypoxia-inducible factor prolyl hydroxylase | - |
Homo sapiens |
PHD2 | - |
Homo sapiens |