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Literature summary for 1.14.11.2 extracted from

  • Rong, H.; Zhang, Y.; Hao, M.; Zou, W.; Yu, J.; Yu, C.; Shi, Q.; Wen, X.
    Effects of dietary hydroxyproline on collagen metabolism, proline 4-hydroxylase activity, and expression of related gene in swim bladder of juvenile Nibea diacanthus (2019), Fish Physiol. Biochem., 45, 1779-1790 .
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
procollagen L-proline + 2-oxoglutarate + O2 Protonibea diacanthus
-
 procollagen trans-4-hydroxy-L-proline + succinate + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Protonibea diacanthus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Protonibea diacanthus
-
swim bladder
-
 Protonibea diacanthus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
procollagen L-proline + 2-oxoglutarate + O2
-
 Protonibea diacanthus procollagen trans-4-hydroxy-L-proline + succinate + CO2
-
 ?

Synonyms

Synonyms Comment Organism
P4H
-
 Protonibea diacanthus
P4Halpha(I)
-
 Protonibea diacanthus
P4Halpha(II)
-
 Protonibea diacanthus
P4Halpha(III)
-
 Protonibea diacanthus
proline 4-hydroxylase
-
 Protonibea diacanthus

Expression

Organism Comment Expression
Protonibea diacanthus the activity of the enzyme (P4H) in liver and swim bladder shows similar trend, showing first increase and then decrease with increasing dietary hydroxyproline. Increased dietary hydroxyproline content corresponds with significant decrease in the mRNA level of P4Halphas in swim bladder up