Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3) cells | Arabidopsis thaliana |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | required for activity | Arabidopsis thaliana |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Arabidopsis thaliana | no activity with [histone H3]-N6,N6-dimethyl-L-lysine4, [histone H3]-N6-methyl-L-lysine4, [histone H3]-N6,N6,N6-trimethyl-L-lysine9, [histone H3]-N6,N6-dimethyl-L-lysine9, [histone H3]-N6,N6,N6-trimethyl-L-lysine27, [histone H3]-N6,N6-dimethyl-L-lysine27, [histone H3]-N6,N6,N6-trimethyl-L-lysine36 and [histone H3]-N6,N6-dimethyl-L-lysine36 | ? | - |
- |
|
[histone H3]-N6,N6,N6-trimethyl-L-lysine4 + 2-oxoglutarate + O2 | Arabidopsis thaliana | - |
[histone H3]-N6,N6-dimethyl-L-lysine4 + succinate + formaldehyde + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | O64752 | - |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA affinity column chromatography | Arabidopsis thaliana |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ARTK(me3)QTARKS + 2-oxoglutarate + O2 | - |
Arabidopsis thaliana | ARTK(me2)QTARKS + succinate + formaldehyde + CO2 | - |
? | |
additional information | no activity with [histone H3]-N6,N6-dimethyl-L-lysine4, [histone H3]-N6-methyl-L-lysine4, [histone H3]-N6,N6,N6-trimethyl-L-lysine9, [histone H3]-N6,N6-dimethyl-L-lysine9, [histone H3]-N6,N6,N6-trimethyl-L-lysine27, [histone H3]-N6,N6-dimethyl-L-lysine27, [histone H3]-N6,N6,N6-trimethyl-L-lysine36 and [histone H3]-N6,N6-dimethyl-L-lysine36 | Arabidopsis thaliana | ? | - |
- |
|
[histone H3]-N6,N6,N6-trimethyl-L-lysine4 + 2-oxoglutarate + O2 | - |
Arabidopsis thaliana | [histone H3]-N6,N6-dimethyl-L-lysine4 + succinate + formaldehyde + CO2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 95000, His-tagged enzyme, SDS-PAGE | Arabidopsis thaliana |
Synonyms | Comment | Organism |
---|---|---|
H3K4me3-specific demethylase | - |
Arabidopsis thaliana |
JMJ15 | - |
Arabidopsis thaliana |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is involved in the control of flowering time by demethylating [histone H3]-N6,N6,N6-trimethyl-L-lysine4 at flowering locus C chromatin | Arabidopsis thaliana |