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Literature summary for extracted from

  • Funk, C.; Koepp, A.E.; Croteau, R.
    Catabolism of camphor in tissue cultures and leaf disks of common sage (Salvia officinalis) (1992), Arch. Biochem. Biophys., 294, 306-313.
    View publication on PubMed


Inhibitors Comment Organism Structure
clotrimazole 84% inhibition at 0.05 mM Salvia officinalis
CO 73% inhibition at CO:O2 ratio of 9:1, activity is partially restored by blue light Salvia officinalis


Localization Comment Organism GeneOntology No. Textmining
membrane light membrane fraction Salvia officinalis 16020


Organism UniProt Comment Textmining
Salvia officinalis

Source Tissue

Source Tissue Comment Organism Textmining
cell suspension culture
Salvia officinalis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(+)-camphor + NADPH + H+ + O2
Salvia officinalis (+)-6-exo-hydroxycamphor + NADP+ + H2O

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
Salvia officinalis


Cofactor Comment Organism Structure
cytochrome P450 enzyme is a cytochrome P450-dependent monooxygenase Salvia officinalis
NADPH absolute requirement for NADPH and O2 Salvia officinalis

General Information

General Information Comment Organism
physiological function pathway for camphor degradation follows the oxidative ring opening sequence from (+)-camphor to 6-hydroxycamphor, 6-oxocamphor, alpha-campholonic acid, and 2-hydroxy-alpha-campholonic acid. The catabolism of camphor via 1,2-campholide is a minor degradative pathway Salvia officinalis