Literature summary for 1.14.13.39 extracted from

Grassi, D.; Lagunas, N.; Amorin, M.; Pinos, H.; Panzica, G.C.; Garcia-Segura, L.M.; Collado, P.
Estrogenic regulation of NADPH-diaphorase in the supraoptic and paraventricular nuclei under acute osmotic stress (2013), Neuroscience, 248, 127-135 .

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Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
hypothalamus	estradiol regulates the nitrergic system in the supraoptic and paraventricular hypothalamic nuclei under acute osmotic stress conditions, but the effects specifically depend on the anatomical subregions and different estrogen receptors	Rattus norvegicus	-

General Information

General Information	Comment	Organism
physiological function	estradiol regulates the nitrergic system in the supraoptic and paraventricular hypothalamic nuclei under acute osmotic stress conditions, but the effects specifically depend on the anatomical subregions and different estrogen receptors. The inhibition of estrogen receptor alpha enhances the effect of 1.5 M NaCl injection, inducing a further decrease in the number of NADPH-diaphorase-positive cells. The estrogen receptor beta agonist enhances and the estrogen receptor beta antagonist blocks the effect of NaCl injection on the number of NADPH-diaphorase-positive neurons in the supraoptic hypothalamic nuclei and in the medial magnocellular subdivision of the paraventricular hypothalamic nuclei	Rattus norvegicus

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Release 2023.1 (January 2023)