Cloned (Comment) | Organism |
---|---|
expression in CHO cells | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetics | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
vesicle | neurosecretory | Rattus norvegicus | 31982 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
copper | inter-copper electron transfer, mechanism, structure, 2 copper atoms per enzyme | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | enzyme catalyzes the production of neurohormones and neurotransmitters | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
[peptide]-glycine + 2 ascorbate + O2 = [peptide]-(2S)-2-hydroxyglycine + 2 monodehydroascorbate + H2O | inter-copper electron transfer, interdomain structure | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
medullary carcinoma cell | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dansyl-Gly-Gly-Ser-CO-NH-CH2-COOH + ascorbate + O2 | substrate contains either protium or deuterium at the CH2-group | Rattus norvegicus | ? | - |
? | |
HOOC-NH-CH2-COOH + ascorbate + O2 | substrate contains either protium or deuterium at the CH2-group | Rattus norvegicus | ? | - |
? | |
additional information | enzyme catalyzes the production of neurohormones and neurotransmitters | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PAM | - |
Rattus norvegicus |
peptidylglycine alpha-amidating monooxygenase | - |
Rattus norvegicus |
peptidylglycine alpha-hydroxylating monooxygenase | - |
Rattus norvegicus |
PHM | - |
Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
17 | - |
dansyl-Gly-Gly-Ser-CO-NH-CH2-COOH | pH 6.0, 37°C, recombinant enzyme | Rattus norvegicus | |
37 | - |
HOOC-NH-CH2-COOH | pH 6.0, 37°C, recombinant enzyme | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6 | - |
assay at | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ascorbate | - |
Rattus norvegicus |