Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2E)-3-(3,4-dihydroxyphenyl)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]prop-2-enamide | - |
Agaricus bisporus | |
(2E)-3-(3,4-dimethoxyphenyl)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]prop-2-enamide | - |
Agaricus bisporus | |
(2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]prop-2-enamide | - |
Agaricus bisporus | |
(2E)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide | - |
Agaricus bisporus | |
(2E)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)prop-2-enamide | - |
Agaricus bisporus | |
(2E)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-(4-hydroxyphenyl)prop-2-enamide | - |
Agaricus bisporus | |
(2E)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-(4-methoxyphenyl)prop-2-enamide | - |
Agaricus bisporus | |
(2E)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-phenylprop-2-enamide | - |
Agaricus bisporus | |
(2Z)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid | - |
Agaricus bisporus | |
(2Z)-3-(3,4-dimethoxyphenyl)prop-2-enoic acid | - |
Agaricus bisporus | |
(2Z)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid | - |
Agaricus bisporus | |
(2Z)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid | - |
Agaricus bisporus | |
(2Z)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid | - |
Agaricus bisporus | |
(2Z)-3-(4-hydroxyphenyl)prop-2-enoic acid | - |
Agaricus bisporus | |
(2Z)-3-(4-methoxyphenyl)prop-2-enoic acid | - |
Agaricus bisporus | |
(2Z)-3-phenylprop-2-enoic acid | - |
Agaricus bisporus | |
5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one | - |
Agaricus bisporus | |
arbutin | - |
Agaricus bisporus | |
bufobutanoic acid | - |
Agaricus bisporus | |
serotonin | - |
Agaricus bisporus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Agaricus bisporus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-tyrosine + O2 | - |
Agaricus bisporus | L-DOPA + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
tyrosinase | - |
Agaricus bisporus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0054 | - |
in 0.1 M phosphate buffer (pH 7.0), at 37°C | Agaricus bisporus | (2E)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide | |
0.008 | - |
in 0.1 M phosphate buffer (pH 7.0), at 37°C | Agaricus bisporus | (2E)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)prop-2-enamide | |
0.008 | - |
in 0.1 M phosphate buffer (pH 7.0), at 37°C | Agaricus bisporus | (2E)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-(4-hydroxyphenyl)prop-2-enamide | |
0.0238 | - |
in 0.1 M phosphate buffer (pH 7.0), at 37°C | Agaricus bisporus | (2E)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-(4-methoxyphenyl)prop-2-enamide | |
0.0404 | - |
in 0.1 M phosphate buffer (pH 7.0), at 37°C | Agaricus bisporus | (2E)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-phenylprop-2-enamide | |
0.0514 | - |
in 0.1 M phosphate buffer (pH 7.0), at 37°C | Agaricus bisporus | 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one | |
0.1152 | - |
in 0.1 M phosphate buffer (pH 7.0), at 37°C | Agaricus bisporus | (2Z)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid | |
0.1213 | - |
in 0.1 M phosphate buffer (pH 7.0), at 37°C | Agaricus bisporus | (2Z)-3-(4-hydroxyphenyl)prop-2-enoic acid | |
0.201 | - |
in 0.1 M phosphate buffer (pH 7.0), at 37°C | Agaricus bisporus | arbutin | |
0.2781 | - |
in 0.1 M phosphate buffer (pH 7.0), at 37°C | Agaricus bisporus | (2E)-3-(3,4-dihydroxyphenyl)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]prop-2-enamide | |
0.3218 | - |
in 0.1 M phosphate buffer (pH 7.0), at 37°C | Agaricus bisporus | (2E)-3-(3,4-dimethoxyphenyl)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]prop-2-enamide | |
0.35 | - |
IC50 above 0.35 mM, in 0.1 M phosphate buffer (pH 7.0), at 37°C | Agaricus bisporus | serotonin | |
0.35 | - |
IC50 above 0.35 mM, in 0.1 M phosphate buffer (pH 7.0), at 37°C | Agaricus bisporus | (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]prop-2-enamide | |
0.35 | - |
IC50 above 0.35 mM, in 0.1 M phosphate buffer (pH 7.0), at 37°C | Agaricus bisporus | (2Z)-3-phenylprop-2-enoic acid | |
0.35 | - |
IC50 above 0.35 mM, in 0.1 M phosphate buffer (pH 7.0), at 37°C | Agaricus bisporus | (2Z)-3-(4-methoxyphenyl)prop-2-enoic acid | |
0.35 | - |
IC50 above 0.35 mM, in 0.1 M phosphate buffer (pH 7.0), at 37°C | Agaricus bisporus | (2Z)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid | |
0.35 | - |
IC50 above 0.35 mM, in 0.1 M phosphate buffer (pH 7.0), at 37°C | Agaricus bisporus | (2Z)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid | |
0.35 | - |
IC50 above 0.35 mM, in 0.1 M phosphate buffer (pH 7.0), at 37°C | Agaricus bisporus | (2Z)-3-(3,4-dimethoxyphenyl)prop-2-enoic acid | |
0.35 | - |
IC50 above 0.35 mM, in 0.1 M phosphate buffer (pH 7.0), at 37°C | Agaricus bisporus | (2Z)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid | |
0.35 | - |
IC50 above 0.35 mM, in 0.1 M phosphate buffer (pH 7.0), at 37°C | Agaricus bisporus | bufobutanoic acid |