Cloned (Comment) | Organism |
---|---|
gene SCD1, phylogenetic tree, sequence comparisons with other isozymes and enzymes from other organisms, overview | Bos taurus |
gene SCD5, DNA and amino acid sequence determination and analysis, phylogenetic tree, sequence comparisons with other isozymes and enzymes from other organisms, overview | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
stearoyl-CoA + ferrocytochrome b5 + O2 + H+ | Bos taurus | - |
oleoyl-CoA + ferricytochrome b5 + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | Q2KIA4 | isozyme SCD5; isozyme SCD5 | - |
Bos taurus | Q9TT94 | isozyme SCD1; isozyme SCD1 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adipose tissue | high expression level of isozyme SCD1 | Bos taurus | - |
adipose tissue | low expression level of isozyme SCD1 | Bos taurus | - |
brain | - |
Bos taurus | - |
brain | specific high expression level of isozyme SCD5, equally distributed between white and gray matter | Bos taurus | - |
heart | - |
Bos taurus | - |
heart | low expression level of isozyme SCD1 | Bos taurus | - |
liver | low expression level of isozyme SCD1 | Bos taurus | - |
lung | - |
Bos taurus | - |
additional information | no expression of isozyme SCD5 in lung | Bos taurus | - |
skeletal muscle | - |
Bos taurus | - |
skeletal muscle | low expression level of isozyme SCD1 | Bos taurus | - |
spleen | low expression level of isozyme SCD1 | Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme also produces cis-9, trans-11 conjugated linoleic acid and palmitoleoyl-CoA | Bos taurus | ? | - |
? | |
stearoyl-CoA + ferrocytochrome b5 + O2 + H+ | - |
Bos taurus | oleoyl-CoA + ferricytochrome b5 + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SCD | - |
Bos taurus |
SCD1 | - |
Bos taurus |
stearoyl-CoA desaturase | - |
Bos taurus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ferrocytochrome b5 | - |
Bos taurus |