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Literature summary for 1.2.4.2 extracted from

  • Condori-Apfata, J.A.; Batista-Silva, W.; Medeiros, D.B.; Vargas, J.R.; Valente, L.M.L.; Heyneke, E.; Perez-Diaz, J.L.; Fernie, A.R.; Araujo, W.L.; Nunes-Nesi, A.
    The Arabidopsis E1 subunit of the 2-oxoglutarate dehydrogenase complex modulates plant growth and seed production (2019), Plant Mol. Biol., 101, 183-202 .
    View publication on PubMed
Search for more literature for 1.2.4.2

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Arabidopsis thaliana 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine Arabidopsis thaliana
-
 [dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana F4IWV2
-
-
Arabidopsis thaliana F4IWV2 isoform 2-OGDH1
-
Arabidopsis thaliana Q9FLH2
-
-
Arabidopsis thaliana Q9FLH2 isoform 2-OGDH2
-

Source Tissue

Source Tissue Comment Organism Textmining
epidermis guard cell-enriched epidermal fragments, higher expression levels of isoform 2-OGDH1 than isoform 2-OGDH2 Arabidopsis thaliana
-
flower
-
 Arabidopsis thaliana
-
flower isoform E1-OGDH2 is slightly more expressed in cauline leaf and flowers Arabidopsis thaliana
-
leaf highest expression Arabidopsis thaliana
-
leaf young, mature, senescent leaves, lesaf blade and midrib, show higher expression levels of isoform 2-OGDH1 than isoform 2-OGDH2. Isoform E1-OGDH2 is slightly more expressed in cauline leaf and flowers Arabidopsis thaliana
-
root
-
 Arabidopsis thaliana
-
root higher expression levels of isoform 2-OGDH1 than isoform 2-OGDH2 Arabidopsis thaliana
-
seedling
-
 Arabidopsis thaliana
-
silique
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine
-
 Arabidopsis thaliana [dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO2
-
 ?

Synonyms

Synonyms Comment Organism
2-OGDH E1 E1 subunit of the 2-oxoglutarate dehydrogenase complex Arabidopsis thaliana
2-OGDH1
-
 Arabidopsis thaliana
2-OGDH2
-
 Arabidopsis thaliana
At3g55410
-
 Arabidopsis thaliana
E1-OGDH1 isoform Arabidopsis thaliana
E1-OGDH2 isoform Arabidopsis thaliana
MPA24.10
-
 Arabidopsis thaliana

General Information

General Information Comment Organism
malfunction the lack in the expression of enzyme genes reduces respiratory rates and affects the photosynthesis Arabidopsis thaliana
metabolism isoform E1-OGDH1 is essential to the final 2-OGDH activity in leaves Arabidopsis thaliana
physiological function the enzyme modulates planth growth Arabidopsis thaliana
physiological function the enzyme modulates planth growth. In reproductive tissues isoform E1-OGDH2 is important in the control of the reserves production during seed development Arabidopsis thaliana
physiological function two genes encode for the E1 subunit of 2-OGDH. Insertion knockout mutant lines for each of the genes exhibit substantial reduction in both respiration and CO2 assimilation rates. Mutant lines exhibit reduced levels of chlorophylls and nitrate, increased levels of sucrose, malate and fumarate and minor changes in total protein and starch levels in leaves. Absence in expression of E1-OGDH2 gene does not affect the silique length, but decreased the number of seeds per silique. In seedlings lacking only the expression of E1-OGDH2 the root growth is invariant from that of wild type seedlings Arabidopsis thaliana
physiological function two genes encode for the E1 subunit of 2-OGDH. Insertion knockout mutant lines for each of the genes exhibit substantial reduction in both respiration and CO2 assimilation rates. Mutant lines exhibit reduced levels of chlorophylls and nitrate, increased levels of sucrose, malate and fumarate and minor changes in total protein and starch levels in leaves. E1-OGDH1 is important during early stages of seedling development, repression of the E1-OGDH1 gene leads to a significative reduction of silique length and the number of seeds per silique Arabidopsis thaliana