Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Klebsiella pneumoniae | B5XRB0 | - |
- |
Klebsiella pneumoniae 342 | B5XRB0 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
fumarate + NADH + H+ | - |
Klebsiella pneumoniae | succinate + NAD+ | - |
? | |
fumarate + NADH + H+ | - |
Klebsiella pneumoniae 342 | succinate + NAD+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
KPK_2907 | - |
Klebsiella pneumoniae |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6 | 6.5 | oxidation of NADH | Klebsiella pneumoniae |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FMN | - |
Klebsiella pneumoniae | |
additional information | no cofactor: NADPH | Klebsiella pneumoniae | |
NADH | NADH is an inherent electron donor for the enzyme | Klebsiella pneumoniae |
Organism | Comment | Expression |
---|---|---|
Klebsiella pneumoniae | induction of FRD synthesis is observed only under anaerobic conditions in the presence of fumarate or malate | up |
General Information | Comment | Organism |
---|---|---|
physiological function | aerobic incubation of FRD with NADH results in O2 consumption. Fumarate reductase activity of FRD significantly exceeds its NADH dehydrogenase activity. During the catalysis of NADH:fumarate oxidoreductase reaction, FRD turnover is limited by a very low rate (about 10/s) of electron transfer between the noncovalently and covalently bound FMN moieties | Klebsiella pneumoniae |