Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-ketohexadecanoyl-CoA | - |
Rattus norvegicus | |
CH3COOK | - |
Rattus norvegicus | |
KBr | - |
Rattus norvegicus | |
KCl | - |
Rattus norvegicus | |
KI | - |
Rattus norvegicus | |
KNO3 | - |
Rattus norvegicus | |
NaCl | - |
Rattus norvegicus | |
NaN3 | - |
Rattus norvegicus | |
NH4Cl | - |
Rattus norvegicus | |
NH4SCN | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.005 | - |
O2 | - |
Rattus norvegicus | |
0.0073 | - |
linoleoyl-CoA | - |
Rattus norvegicus | |
0.0096 | - |
stearoyl-CoA | - |
Rattus norvegicus | |
0.011 | - |
oleoyl-CoA | - |
Rattus norvegicus | |
0.011 | - |
myristoyl-CoA | - |
Rattus norvegicus | |
0.0116 | - |
palmitoyl-CoA | - |
Rattus norvegicus | |
0.0116 | - |
myristoyl-CoA | - |
Rattus norvegicus | |
0.013 | - |
lauroyl-CoA | - |
Rattus norvegicus | |
0.02 | - |
decanoyl-CoA | - |
Rattus norvegicus | |
0.027 | - |
lauroyl-CoA | liver enzyme | Rattus norvegicus | |
0.058 | - |
octanoyl-CoA | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
peroxisome | - |
Rattus norvegicus | 5777 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
139000 | - |
sedimentation equilibrium method | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + O2 | Rattus norvegicus | involved in beta-oxidation of fatty acids in peroxisomes and glyoxysomes, respectively | trans-2,3-dehydroacyl-CoA + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
2.04 | - |
purified enzyme | Rattus norvegicus |
Storage Stability | Organism |
---|---|
-20°C, for at least 1 month | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + O2 | 3'-phosphate on the ribose ring and the structure of the adenine moiety are essential for substrate recognition, specificity is relatively low with respect to the structure of the pantric acid moiety | Rattus norvegicus | trans-2,3-dehydroacyl-CoA + H2O2 | - |
? | |
acyl-CoA + O2 | involved in beta-oxidation of fatty acids in peroxisomes and glyoxysomes, respectively | Rattus norvegicus | trans-2,3-dehydroacyl-CoA + H2O2 | - |
? | |
decanoyl-CoA + O2 | - |
Rattus norvegicus | trans-2-decenoyl-CoA + H2O2 | - |
? | |
lauroyl-CoA + O2 | - |
Rattus norvegicus | trans-2-dodecenoyl-CoA + H2O2 | - |
? | |
linoleoyl-CoA + O2 | - |
Rattus norvegicus | 2-trans-9-trans-12-trans-octadecatrienoyl-CoA + H2O2 | - |
? | |
myristoyl-CoA + O2 | - |
Rattus norvegicus | trans-2-tetradecenoyl-CoA + H2O2 | - |
? | |
octanoyl-CoA + O2 | - |
Rattus norvegicus | trans-2-octenoyl-CoA + H2O2 | - |
? | |
oleoyl-CoA + O2 | - |
Rattus norvegicus | 2-trans-9-trans-octadecendienoyl-CoA + H2O2 | - |
? | |
palmitoyl-CoA + O2 | - |
Rattus norvegicus | 2-trans-hexadecenoyl-CoA + H2O2 | - |
? | |
stearoyl-CoA + O2 | - |
Rattus norvegicus | trans-2-octadecenoyl-CoA + H2O2 | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
- |
Rattus norvegicus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
7 | 10 | pH 7: about 30% of activity maximum, pH 10: about 5% of activity maximum, inactive below pH 6.5 | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | prosthetic group | Rattus norvegicus | |
FAD | flavoprotein | Rattus norvegicus | |
FAD | 1.22 mol per mol of enzyme | Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00047 | - |
3-ketohexadecanoyl-CoA | - |
Rattus norvegicus |