Cloned (Comment) | Organism |
---|---|
expressed in Saccharomyces cerevisiae | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
peroxisome | - |
Homo sapiens | 5777 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O15254 | - |
- |
Homo sapiens | Q15067 | - |
- |
Homo sapiens | Q99424 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Homo sapiens | - |
liver | highest expression | Homo sapiens | - |
pancreas | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
decanoyl-CoA + O2 | - |
Homo sapiens | trans-2,3-dehydrodecanoyl-CoA + H2O2 | - |
? | |
hexadecanoyl-CoA + O2 | - |
Homo sapiens | trans-2,3-dehydrohexadecanoyl-CoA + H2O2 | - |
? | |
additional information | isoform ACOX1 is responsible for the oxidation of straight-chain fatty acids with different chain lengths | Homo sapiens | ? | - |
- |
|
additional information | isoform ACOX2 is the only human acyl-CoA oxidase involved in bile acid biosynthesis, and is involved in the degradation of the branched-chain fatty acids | Homo sapiens | ? | - |
- |
|
additional information | isoform ACOX3 is involved in the degradation of the branched-chain fatty acids | Homo sapiens | ? | - |
- |
|
pristanoyl-CoA + O2 | - |
Homo sapiens | trans-2,3-dehydropristanoyl-CoA + H2O2 | - |
? | |
trihydroxycholestanoyl-CoA + O2 | - |
Homo sapiens | trans-2,3-dehydrotrihydroxycholestanoyl-CoA + H2O2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 51000, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
ACOX1 | isoform | Homo sapiens |
ACOX2 | isoform | Homo sapiens |
ACOX3 | isoform | Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | isoform ACOX2 deficiency leads to a Zellweger spectrum disorder lacking functional peroxisomes | Homo sapiens |