Application | Comment | Organism |
---|---|---|
medicine | inhibitor may become a lead for further development for treating non-insulin-dependent diabetes mellitus | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | not inhibited by trans-2,trans-4-octadienoyl-CoA and oct-2-en-4-ynoyl-CoA | Rattus norvegicus | |
oct-4-en-2-ynoyl-CoA | irreversible inhibitor, active-site directed, enzyme protected by 2-octenoyl-CoA | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
octanoyl-CoA + phenazine methosulfate + 2,6-dichloroindophenol | - |
Rattus norvegicus | 2-octenoyl-CoA + reduced acceptor | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MCAD | - |
Rattus norvegicus |
medium chain-specific acyl-CoA oxidase | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | is not the target of the inhibitor | Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.011 | - |
oct-4-en-2-ynoyl-CoA | - |
Rattus norvegicus |