Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
5,10-methylenetetrahydrofolate + NH3 + CO2 + NADH | Rattus norvegicus | - |
glycine + tetrahydrofolate + NAD+ | - |
r | |
glycine + tetrahydrofolate + NAD+ | Rattus norvegicus | - |
5,10-methylenetetrahydrofolate + NH3 + CO2 + NADH | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
purification of P-protein, and for T-protein. The procedure leads to the isolation of a nearly homogeneous form of T-protein but P-protein still is heterogeneous | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5,10-methylenetetrahydrofolate + NH3 + CO2 + NADH | - |
Rattus norvegicus | glycine + tetrahydrofolate + NAD+ | - |
r | |
glycine + tetrahydrofolate + NAD+ | - |
Rattus norvegicus | 5,10-methylenetetrahydrofolate + NH3 + CO2 + NADH | - |
r |
Subunits | Comment | Organism |
---|---|---|
multimer | x * 33,000, component T-protein | Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
physiological function | the reversible glycine cleavage system is composed of four protein components named as P-, H-, L-, and T-protein, respectively. P-protein catalyzes the decarboxylation of glycine or its reverse reaction in the presence of H-protein, and T-protein participates in the formation of one carbon unit and ammonia or the reverse reaction | Rattus norvegicus |