Literature summary for 1.4.3.13 extracted from

Li, S.Y.; Yan, J.Q.; Song, Z.; Liu, Y.F.; Song, M.J.; Qin, J.W.; Yang, Z.M.; Liang, X.H.
Molecular characterization of lysyl oxidase-mediated extracellular matrix remodeling during mouse decidualization (2017), FEBS Lett., 591, 1394-1407 .

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Metals/Ions

Metals/Ions	Comment	Organism	Structure
Cu2+	copper-containing enzyme	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	P28301	-	-
Mus musculus CD-1	P28301	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
blastocyst	subluminal stroma surrounding the implanting blastocyst on day 5 of pregnancy	Mus musculus	-
decidual cell	from days 6 to 8 of pregnancy, the signals for Lox mRNA and protein are strongly detected in the decidual cells	Mus musculus	-
uterus	-	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
LOX	-	Mus musculus

Expression

Organism	Comment	Expression
Mus musculus	on day 5, the signals for Lox mRNA and protein are detected in the subluminal stroma surrounding the implanting blastocyst at implantation sites while no signal is observed at interimplantation sites. From days 6 to 8 of pregnancy, the signals for Lox mRNA and protein are strongly detected in the decidual cells. The expression of Lox is under the control of estrogen via the GSK-3beta/beta-catenin/c-myc pathway	up

General Information

General Information	Comment	Organism
metabolism	the enzyme catalyzes cross-linking of collagen and elastin in the extracellular matrix	Mus musculus
physiological function	crucial role of Lox in endometrial stromal cells	Mus musculus

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Release 2023.1 (January 2023)