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Literature summary for 1.5.3.1 extracted from

  • Shoji, M.; Abe, Y.; Boero, M.; Shigeta, Y.; Nishiya, Y.
    Reaction mechanism of N-cyclopropylglycine oxidation by monomeric sarcosine oxidase (2020), Phys. Chem. Chem. Phys., 22, 16552-16561 .
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
N-cyclopropylglycine reaction leads to an inactivated species. The polar mechanism is energetically the most favorable. The first rate-limiting step is the N-cyclopropylglycine binding to the flavin ring which simultaneously proceeds with the ring-opening of the N-cyclopropylglycine cyclopropyl group. This step corresponds to the nucleophilic attack of the cyclopropyl group (C3 atom) to the flavin ring (C4a atom) Bacillus sp. B-0618

Organism

Organism UniProt Comment Textmining
Bacillus sp. B-0618 P40859
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