genes mgdA, mgdB, and mgdC, encoding subunits A, B, and large subunit c, the enzyme is encoded in a gene cluster essential for operation of the N-methylglutamate pathway, genetic structure
Methyloversatilis universalis
N-methyl-L-glutamate + acceptor + H2O
Methyloversatilis universalis
L-glutamate + formaldehyde + reduced acceptor
?
N-methyl-L-glutamate + acceptor + H2O
Methyloversatilis universalis FAM5
L-glutamate + formaldehyde + reduced acceptor
?
Methyloversatilis universalis
genes mgdA, mgdB, and mgdC, encoding subunits A, B, and large subunit c
Methyloversatilis universalis FAM5
genes mgdA, mgdB, and mgdC, encoding subunits A, B, and large subunit c
N-methyl-L-glutamate + acceptor + H2O
700286
Methyloversatilis universalis
L-glutamate + formaldehyde + reduced acceptor
?
N-methyl-L-glutamate + acceptor + H2O
700286
Methyloversatilis universalis FAM5
L-glutamate + formaldehyde + reduced acceptor
?
N-methyl-L-glutamate + oxidized 2,6-dichlorophenolindophenol + H2O
700286
Methyloversatilis universalis
L-glutamate + formaldehyde + reduced 2,6-dichlorophenolindophenol
?
N-methyl-L-glutamate + oxidized 2,6-dichlorophenolindophenol + H2O
700286
Methyloversatilis universalis FAM5
L-glutamate + formaldehyde + reduced 2,6-dichlorophenolindophenol
?
N-methyl-L-glutamate:oxidoreductase
Methyloversatilis universalis
N-methylglutamate dehydrogenase
Methyloversatilis universalis
NMGDH
Methyloversatilis universalis
genes mgdA, mgdB, and mgdC, encoding subunits A, B, and large subunit c, the enzyme is encoded in a gene cluster essential for operation of the N-methylglutamate pathway, genetic structure
Methyloversatilis universalis
N-methyl-L-glutamate + acceptor + H2O
Methyloversatilis universalis
L-glutamate + formaldehyde + reduced acceptor
?
N-methyl-L-glutamate + acceptor + H2O
Methyloversatilis universalis FAM5
L-glutamate + formaldehyde + reduced acceptor
?
N-methyl-L-glutamate + acceptor + H2O
700286
Methyloversatilis universalis
L-glutamate + formaldehyde + reduced acceptor
?
N-methyl-L-glutamate + acceptor + H2O
700286
Methyloversatilis universalis FAM5
L-glutamate + formaldehyde + reduced acceptor
?
N-methyl-L-glutamate + oxidized 2,6-dichlorophenolindophenol + H2O
700286
Methyloversatilis universalis
L-glutamate + formaldehyde + reduced 2,6-dichlorophenolindophenol
?
N-methyl-L-glutamate + oxidized 2,6-dichlorophenolindophenol + H2O
700286
Methyloversatilis universalis FAM5
L-glutamate + formaldehyde + reduced 2,6-dichlorophenolindophenol
?
metabolism
SoxBDAG, encoding sarcosine dehydrogenase,may be involved in oxidation of N-methyl-L-glutamate, overview
Methyloversatilis universalis
additional information
the enzyme is encoded in a gene cluster essential for operation of the N-methylglutamate pathway in the methylotrophic beta-proteobacterium Methyloversatilis universalis FAM5. The enzyme contains an aminomethyltransferase folate-binding domain near the C-terminus of its large subunit
Methyloversatilis universalis
metabolism
SoxBDAG, encoding sarcosine dehydrogenase,may be involved in oxidation of N-methyl-L-glutamate, overview
Methyloversatilis universalis
additional information
the enzyme is encoded in a gene cluster essential for operation of the N-methylglutamate pathway in the methylotrophic beta-proteobacterium Methyloversatilis universalis FAM5. The enzyme contains an aminomethyltransferase folate-binding domain near the C-terminus of its large subunit
Methyloversatilis universalis
700286
Latypova
Genetics of the glutamate-medi ...
Methyloversatilis universalis, Methyloversatilis universalis FAM5
Mol. Microbiol.
75
426-439
2010
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723999
Chen
gamma-Glutamylmethylamide is a ...
Methylocella silvestris, Methylocella silvestris BL2
Appl. Environ. Microbiol.
76
4530-4537
2010
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437750
Biville
-
Physiological properties of a ...
Methylobacterium organophilum
FEMS Microbiol. Lett.
52
53-58
1988
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437749
Janvier
-
Methylophaga marina gen nov., ...
Methylophaga marina, Methylophaga thalassica
Int. J. Syst. Bacteriol.
35
131-139
1985
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437748
Boulton
-
N-Methylglutamate dehydrogenas ...
bacterium AT2, Hyphomicrobium vulgare, Pseudomonas sp., Aminobacter aminovorans, Pseudomonas methylica, Aminobacter aminovorans AM1, Pseudomonas sp. MA / M.A. / ATCC 23819, Hyphomicrobium vulgare ZV, Hyphomicrobium vulgare 3
J. Gen. Microbiol.
117
293-304
1980
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18
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6
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2
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1
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1
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437747
Bamforth
The kinetic mechanism of N-met ...
Aminobacter aminovorans
Biochem. Soc. Trans.
6
193-195
1978
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437745
Bamforth
Solubilization, partial purifi ...
Aminobacter aminovorans, Aminobacter aminovorans AM1, Aminobacter aminovorans N.C.I.B. 9039
Biochem. J.
161
357-370
1977
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6
7
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1
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13
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5
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19
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2
19
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437746
Bamforth
The molecular size of N-methyl ...
Aminobacter aminovorans
Biochem. J.
167
509-512
1977
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437744
Bamforth
-
Solubilization and partial pur ...
Pseudomonas sp., Aminobacter aminovorans, Aminobacter aminovorans AM1, Pseudomonas sp. MA / M.A. / ATCC 23819
Biochem. Soc. Trans.
3
1066-1069
1975
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437743
Hersh
N-methylglutamate dehydrogenas ...
Pseudomonas sp., Pseudomonas sp. MA / M.A. / ATCC 23819
Arch. Biochem. Biophys.
150
219-226
1972
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437742
Hersh
An N-methyl glutamate dehydrog ...
Pseudomonas sp., Pseudomonas sp. MA / M.A. / ATCC 23819
Arch. Biochem. Biophys.
145
115-120
1971
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