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Literature summary for 1.7.2.3 extracted from
- TMAO reductase, a biomarker for gut permeability defect induced inflammation, in mouse model of chronic kidney disease and dextran sulfate solution-induced mucositis (2021), Asian Pac. J. Allergy Immunol., FEHLT, 0000 .
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | detection of the enzyme in blood is associated with gut leakage and systemic inflammation. The enzyme is a biomarker for chronic kidney disease vascular complications | uncultured bacterium |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 172000 | - |
gel filtration | uncultured bacterium |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| trimethylamine N-oxide + 2 (ferrocytochrome c)-subunit + 2 H+ | uncultured bacterium | - |
trimethylamine + 2 (ferricytochrome c)-subunit + H2O | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| uncultured bacterium | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| trimethylamine N-oxide + 2 (ferrocytochrome c)-subunit + 2 H+ | - |
uncultured bacterium | trimethylamine + 2 (ferricytochrome c)-subunit + H2O | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TMAO reductase | - |
uncultured bacterium |
Expression
| Organism | Comment | Expression |
|---|---|---|
| uncultured bacterium | serum enzyme level is elevated in chronic kidney disease mice and patients with chronic kidney disease | up |
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Release 2023.1 (January 2023)
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