KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0014 | - |
hydroxylamine | pH 7.5, 60°C | Methylacidiphilum fumariolicum |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
250000 | - |
and 500000, native PAGE | Methylacidiphilum fumariolicum |
500000 | - |
and 250000, native PAGE | Methylacidiphilum fumariolicum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
hydroxylamine + 3 ferricytochrome c | Methylacidiphilum fumariolicum | - |
nitric oxide + 3 ferrocytochrome c + 3 H+ | - |
? | |
hydroxylamine + 3 ferricytochrome c | Methylacidiphilum fumariolicum SolV | - |
nitric oxide + 3 ferrocytochrome c + 3 H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Methylacidiphilum fumariolicum | - |
- |
- |
Methylacidiphilum fumariolicum SolV | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
hydroxylamine + 3 ferricytochrome c | - |
Methylacidiphilum fumariolicum | nitric oxide + 3 ferrocytochrome c + 3 H+ | - |
? | |
hydroxylamine + 3 ferricytochrome c | - |
Methylacidiphilum fumariolicum SolV | nitric oxide + 3 ferrocytochrome c + 3 H+ | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 83860, calculated from sequence | Methylacidiphilum fumariolicum |
Synonyms | Comment | Organism |
---|---|---|
haoA | - |
Methylacidiphilum fumariolicum |
Mfumv2_2472 | - |
Methylacidiphilum fumariolicum |
mHAO | - |
Methylacidiphilum fumariolicum |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
60 | - |
- |
Methylacidiphilum fumariolicum |
Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|
80 | - |
active up to | Methylacidiphilum fumariolicum |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
7.2 | - |
hydroxylamine | pH 7.5, 60°C | Methylacidiphilum fumariolicum |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Methylacidiphilum fumariolicum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | 9 heme c moieties per subunit | Methylacidiphilum fumariolicum |
General Information | Comment | Organism |
---|---|---|
physiological function | in methanotrophs, mHAO efficiently removes hydroxylamine, which severely inhibits calcium-dependent and lanthanide-dependent methanol dehydrogenases | Methylacidiphilum fumariolicum |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
5100 | - |
hydroxylamine | pH 7.5, 60°C | Methylacidiphilum fumariolicum |