Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-((2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)methyl)-4-methylpiperazine | - |
Leishmania donovani | |
1-((2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)methyl)-4-methylpiperazine | - |
Plasmodium falciparum | |
1-((2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)methyl)-4-methylpiperazine | - |
Trypanosoma brucei rhodesiense | |
1-((2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)methyl)-4-methylpiperazine | 36% inhibition at 0.1 mM | Trypanosoma cruzi | |
1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)-4-((1-(2,6-bis(phenylthio)phenyl)-1H-1,2,3-triazol-4-yl)methyl)piperazine | - |
Leishmania donovani | |
1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)-4-((1-(2,6-bis(phenylthio)phenyl)-1H-1,2,3-triazol-4-yl)methyl)piperazine | - |
Plasmodium falciparum | |
1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)-4-((1-(2,6-bis(phenylthio)phenyl)-1H-1,2,3-triazol-4-yl)methyl)piperazine | - |
Trypanosoma brucei rhodesiense | |
1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)-4-((1-(2,6-bis(phenylthio)phenyl)-1H-1,2,3-triazol-4-yl)methyl)piperazine | - |
Trypanosoma cruzi | |
1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)-4-((2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-4-yl)methyl)piperazine | - |
Leishmania donovani | |
1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)-4-((2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-4-yl)methyl)piperazine | - |
Plasmodium falciparum | |
1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)-4-((2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-4-yl)methyl)piperazine | - |
Trypanosoma brucei rhodesiense | |
1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)-4-((2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-4-yl)methyl)piperazine | - |
Trypanosoma cruzi | |
1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)piperidine | - |
Leishmania donovani | |
1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)piperidine | - |
Plasmodium falciparum | |
1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)piperidine | - |
Trypanosoma brucei rhodesiense | |
1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)piperidine | - |
Trypanosoma cruzi | |
1-(2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)-N-((2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)methyl)-N,N-dimethylmethanaminium formate | - |
Leishmania donovani | |
1-(2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)-N-((2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)methyl)-N,N-dimethylmethanaminium formate | - |
Plasmodium falciparum | |
1-(2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)-N-((2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)methyl)-N,N-dimethylmethanaminium formate | - |
Trypanosoma brucei rhodesiense | |
1-(2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)-N-((2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)methyl)-N,N-dimethylmethanaminium formate | 86% inhibition at 0.04 mM | Trypanosoma cruzi | |
1-(2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)-N-(3,4-dichlorobenzyl)-N,N-dimethylmethanaminium formate | - |
Leishmania donovani | |
1-(2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)-N-(3,4-dichlorobenzyl)-N,N-dimethylmethanaminium formate | - |
Plasmodium falciparum | |
1-(2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)-N-(3,4-dichlorobenzyl)-N,N-dimethylmethanaminium formate | - |
Trypanosoma brucei rhodesiense | |
1-(2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)-N-(3,4-dichlorobenzyl)-N,N-dimethylmethanaminium formate | 52% inhibition at 0.04 mM | Trypanosoma cruzi | |
1-([2-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]methyl)-4-methylpiperazine | - |
Leishmania donovani | |
1-([2-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]methyl)-4-methylpiperazine | - |
Plasmodium falciparum | |
1-([2-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]methyl)-4-methylpiperazine | - |
Trypanosoma brucei rhodesiense | |
1-([2-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]methyl)-4-methylpiperazine | 16% inhibition at 0.1 mM | Trypanosoma cruzi | |
1-[1-(1-benzothiophen-2-yl)cyclohexyl]-4-([1-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-1,2,3-triazol-4-yl]methyl)piperazine | - |
Leishmania donovani | |
1-[1-(1-benzothiophen-2-yl)cyclohexyl]-4-([1-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-1,2,3-triazol-4-yl]methyl)piperazine | - |
Plasmodium falciparum | |
1-[1-(1-benzothiophen-2-yl)cyclohexyl]-4-([1-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-1,2,3-triazol-4-yl]methyl)piperazine | - |
Trypanosoma brucei rhodesiense | |
1-[1-(1-benzothiophen-2-yl)cyclohexyl]-4-([1-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-1,2,3-triazol-4-yl]methyl)piperazine | 28% inhibition at 0.1 mM | Trypanosoma cruzi | |
1-[1-(1-benzothiophen-2-yl)cyclohexyl]-4-([2-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-imidazol-4-yl]methyl)piperazine | - |
Leishmania donovani | |
1-[1-(1-benzothiophen-2-yl)cyclohexyl]-4-([2-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-imidazol-4-yl]methyl)piperazine | - |
Plasmodium falciparum | |
1-[1-(1-benzothiophen-2-yl)cyclohexyl]-4-([2-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-imidazol-4-yl]methyl)piperazine | - |
Trypanosoma brucei rhodesiense | |
1-[1-(1-benzothiophen-2-yl)cyclohexyl]-4-([2-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-imidazol-4-yl]methyl)piperazine | 28% inhibition at 0.1 mM | Trypanosoma cruzi | |
1-[2-[2,6-bis(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]-N,N-dimethylmethanamine | - |
Leishmania donovani | |
1-[2-[2,6-bis(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]-N,N-dimethylmethanamine | - |
Plasmodium falciparum | |
1-[2-[2,6-bis(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]-N,N-dimethylmethanamine | - |
Trypanosoma brucei rhodesiense | |
1-[2-[2,6-bis(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]-N,N-dimethylmethanamine | 25% inhibition at 0.1 mM | Trypanosoma cruzi | |
2-(1-cyclopentylcyclohexyl)-1-benzothiophene | - |
Leishmania donovani | |
2-(1-cyclopentylcyclohexyl)-1-benzothiophene | - |
Plasmodium falciparum | |
2-(1-cyclopentylcyclohexyl)-1-benzothiophene | - |
Trypanosoma brucei rhodesiense | |
2-(1-cyclopentylcyclohexyl)-1-benzothiophene | 61% inhibition at 0.04 mM | Trypanosoma cruzi | |
2-[5-[(4-methylpiperazin-1-yl)methyl]-1H-imidazol-2-yl]-N-phenyl-3-(phenylsulfanyl)aniline | - |
Leishmania donovani | |
2-[5-[(4-methylpiperazin-1-yl)methyl]-1H-imidazol-2-yl]-N-phenyl-3-(phenylsulfanyl)aniline | - |
Plasmodium falciparum | |
2-[5-[(4-methylpiperazin-1-yl)methyl]-1H-imidazol-2-yl]-N-phenyl-3-(phenylsulfanyl)aniline | - |
Trypanosoma brucei rhodesiense | |
2-[5-[(4-methylpiperazin-1-yl)methyl]-1H-imidazol-2-yl]-N-phenyl-3-(phenylsulfanyl)aniline | 58% inhibition at 0.1 mM | Trypanosoma cruzi | |
2-[5-[(dimethylamino)methyl]-1H-imidazol-2-yl]-N-phenyl-3-(phenylsulfanyl)aniline | - |
Leishmania donovani | |
2-[5-[(dimethylamino)methyl]-1H-imidazol-2-yl]-N-phenyl-3-(phenylsulfanyl)aniline | - |
Plasmodium falciparum | |
2-[5-[(dimethylamino)methyl]-1H-imidazol-2-yl]-N-phenyl-3-(phenylsulfanyl)aniline | - |
Trypanosoma brucei rhodesiense | |
2-[5-[(dimethylamino)methyl]-1H-imidazol-2-yl]-N-phenyl-3-(phenylsulfanyl)aniline | 42% inhibition at 0.1 mM | Trypanosoma cruzi | |
N-([2-[2,6-bis(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]methyl)-N-ethylethanamine | - |
Leishmania donovani | |
N-([2-[2,6-bis(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]methyl)-N-ethylethanamine | - |
Plasmodium falciparum | |
N-([2-[2,6-bis(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]methyl)-N-ethylethanamine | - |
Trypanosoma brucei rhodesiense | |
N-([2-[2,6-bis(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]methyl)-N-ethylethanamine | 46% inhibition at 0.1 mM | Trypanosoma cruzi |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Leishmania donovani | - |
- |
- |
Plasmodium falciparum | - |
- |
- |
Trypanosoma brucei rhodesiense | - |
- |
- |
Trypanosoma cruzi | P28593 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
trypanothione disulfide + NADPH + H+ | - |
Leishmania donovani | trypanothione + NADP+ | - |
? | |
trypanothione disulfide + NADPH + H+ | - |
Plasmodium falciparum | trypanothione + NADP+ | - |
? | |
trypanothione disulfide + NADPH + H+ | - |
Trypanosoma brucei rhodesiense | trypanothione + NADP+ | - |
? | |
trypanothione disulfide + NADPH + H+ | - |
Trypanosoma cruzi | trypanothione + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
trypanothione reductase | - |
Leishmania donovani |
trypanothione reductase | - |
Plasmodium falciparum |
trypanothione reductase | - |
Trypanosoma brucei rhodesiense |
trypanothione reductase | - |
Trypanosoma cruzi |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Leishmania donovani | |
FAD | - |
Plasmodium falciparum | |
FAD | - |
Trypanosoma brucei rhodesiense | |
FAD | - |
Trypanosoma cruzi | |
NADPH | - |
Leishmania donovani | |
NADPH | - |
Plasmodium falciparum | |
NADPH | - |
Trypanosoma brucei rhodesiense | |
NADPH | - |
Trypanosoma cruzi |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0011 | - |
1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)-4-((1-(2,6-bis(phenylthio)phenyl)-1H-1,2,3-triazol-4-yl)methyl)piperazine | at 25°C, pH not specified in the publication | Trypanosoma cruzi | |
0.002 | - |
1-(2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)-N-((2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)methyl)-N,N-dimethylmethanaminium formate | at 25°C, pH not specified in the publication | Trypanosoma cruzi | |
0.005 | - |
1-(2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)-N-(3,4-dichlorobenzyl)-N,N-dimethylmethanaminium formate | at 25°C, pH not specified in the publication | Trypanosoma cruzi |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00009 | - |
at 25°C, pH not specified in the publication | Plasmodium falciparum | 1-[2-[2,6-bis(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]-N,N-dimethylmethanamine | |
0.00012 | - |
at 25°C, pH not specified in the publication | Plasmodium falciparum | 1-(2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)-N-((2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)methyl)-N,N-dimethylmethanaminium formate | |
0.00013 | - |
at 25°C, pH not specified in the publication | Plasmodium falciparum | 1-(2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)-N-(3,4-dichlorobenzyl)-N,N-dimethylmethanaminium formate | |
0.00023 | - |
at 25°C, pH not specified in the publication | Trypanosoma brucei rhodesiense | 1-(2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)-N-(3,4-dichlorobenzyl)-N,N-dimethylmethanaminium formate | |
0.00023 | - |
at 25°C, pH not specified in the publication | Plasmodium falciparum | 1-[1-(1-benzothiophen-2-yl)cyclohexyl]-4-([2-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-imidazol-4-yl]methyl)piperazine | |
0.00028 | - |
at 25°C, pH not specified in the publication | Plasmodium falciparum | N-([2-[2,6-bis(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]methyl)-N-ethylethanamine | |
0.00032 | - |
at 25°C, pH not specified in the publication | Trypanosoma brucei rhodesiense | 1-(2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)-N-((2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)methyl)-N,N-dimethylmethanaminium formate | |
0.00039 | - |
at 25°C, pH not specified in the publication | Plasmodium falciparum | 1-[1-(1-benzothiophen-2-yl)cyclohexyl]-4-([1-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-1,2,3-triazol-4-yl]methyl)piperazine | |
0.00082 | - |
at 25°C, pH not specified in the publication | Plasmodium falciparum | 2-[5-[(4-methylpiperazin-1-yl)methyl]-1H-imidazol-2-yl]-N-phenyl-3-(phenylsulfanyl)aniline | |
0.00088 | - |
at 25°C, pH not specified in the publication | Trypanosoma brucei rhodesiense | 2-[5-[(dimethylamino)methyl]-1H-imidazol-2-yl]-N-phenyl-3-(phenylsulfanyl)aniline | |
0.00088 | - |
at 25°C, pH not specified in the publication | Trypanosoma brucei rhodesiense | N-([2-[2,6-bis(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]methyl)-N-ethylethanamine | |
0.0011 | - |
at 25°C, pH not specified in the publication | Leishmania donovani | 1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)-4-((1-(2,6-bis(phenylthio)phenyl)-1H-1,2,3-triazol-4-yl)methyl)piperazine | |
0.0013 | - |
at 25°C, pH not specified in the publication | Plasmodium falciparum | 1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)-4-((1-(2,6-bis(phenylthio)phenyl)-1H-1,2,3-triazol-4-yl)methyl)piperazine | |
0.0016 | - |
at 25°C, pH not specified in the publication | Trypanosoma brucei rhodesiense | 1-[1-(1-benzothiophen-2-yl)cyclohexyl]-4-([2-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-imidazol-4-yl]methyl)piperazine | |
0.00173 | - |
at 25°C, pH not specified in the publication | Trypanosoma brucei rhodesiense | 1-[2-[2,6-bis(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]-N,N-dimethylmethanamine | |
0.00186 | - |
at 25°C, pH not specified in the publication | Leishmania donovani | 1-(2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)-N-(3,4-dichlorobenzyl)-N,N-dimethylmethanaminium formate | |
0.00211 | - |
at 25°C, pH not specified in the publication | Trypanosoma brucei rhodesiense | 1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)-4-((1-(2,6-bis(phenylthio)phenyl)-1H-1,2,3-triazol-4-yl)methyl)piperazine | |
0.00233 | - |
at 25°C, pH not specified in the publication | Trypanosoma cruzi | 1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)-4-((2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-4-yl)methyl)piperazine | |
0.0024 | - |
at 25°C, pH not specified in the publication | Trypanosoma cruzi | 1-(2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)-N-(3,4-dichlorobenzyl)-N,N-dimethylmethanaminium formate | |
0.00253 | - |
at 25°C, pH not specified in the publication | Leishmania donovani | 1-(2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)-N-((2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)methyl)-N,N-dimethylmethanaminium formate | |
0.00323 | - |
at 25°C, pH not specified in the publication | Plasmodium falciparum | 1-([2-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]methyl)-4-methylpiperazine | |
0.00327 | - |
at 25°C, pH not specified in the publication | Trypanosoma brucei rhodesiense | 2-[5-[(4-methylpiperazin-1-yl)methyl]-1H-imidazol-2-yl]-N-phenyl-3-(phenylsulfanyl)aniline | |
0.00401 | - |
at 25°C, pH not specified in the publication | Leishmania donovani | 1-[1-(1-benzothiophen-2-yl)cyclohexyl]-4-([2-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-imidazol-4-yl]methyl)piperazine | |
0.00424 | - |
at 25°C, pH not specified in the publication | Trypanosoma cruzi | 1-[1-(1-benzothiophen-2-yl)cyclohexyl]-4-([2-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-imidazol-4-yl]methyl)piperazine | |
0.00458 | - |
at 25°C, pH not specified in the publication | Trypanosoma brucei rhodesiense | 1-([2-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]methyl)-4-methylpiperazine | |
0.00627 | - |
at 25°C, pH not specified in the publication | Plasmodium falciparum | 2-[5-[(dimethylamino)methyl]-1H-imidazol-2-yl]-N-phenyl-3-(phenylsulfanyl)aniline | |
0.00633 | - |
at 25°C, pH not specified in the publication | Trypanosoma cruzi | 1-(2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)-N-((2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)methyl)-N,N-dimethylmethanaminium formate | |
0.00656 | - |
at 25°C, pH not specified in the publication | Leishmania donovani | N-([2-[2,6-bis(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]methyl)-N-ethylethanamine | |
0.0106 | - |
at 25°C, pH not specified in the publication | Trypanosoma cruzi | 1-[1-(1-benzothiophen-2-yl)cyclohexyl]-4-([1-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-1,2,3-triazol-4-yl]methyl)piperazine | |
0.0116 | - |
at 25°C, pH not specified in the publication | Trypanosoma cruzi | N-([2-[2,6-bis(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]methyl)-N-ethylethanamine | |
0.0122 | - |
at 25°C, pH not specified in the publication | Trypanosoma cruzi | 1-[2-[2,6-bis(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]-N,N-dimethylmethanamine | |
0.0239 | - |
at 25°C, pH not specified in the publication | Leishmania donovani | 1-[1-(1-benzothiophen-2-yl)cyclohexyl]-4-([1-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-1,2,3-triazol-4-yl]methyl)piperazine | |
0.025 | - |
at 25°C, pH not specified in the publication | Trypanosoma brucei rhodesiense | 1-[1-(1-benzothiophen-2-yl)cyclohexyl]-4-([1-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-1,2,3-triazol-4-yl]methyl)piperazine | |
0.0337 | - |
at 25°C, pH not specified in the publication | Leishmania donovani | 1-[2-[2,6-bis(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]-N,N-dimethylmethanamine | |
0.05212 | - |
at 25°C, pH not specified in the publication | Trypanosoma cruzi | 1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)-4-((1-(2,6-bis(phenylthio)phenyl)-1H-1,2,3-triazol-4-yl)methyl)piperazine | |
0.0539 | - |
at 25°C, pH not specified in the publication | Trypanosoma cruzi | 2-[5-[(4-methylpiperazin-1-yl)methyl]-1H-imidazol-2-yl]-N-phenyl-3-(phenylsulfanyl)aniline | |
0.0759 | - |
at 25°C, pH not specified in the publication | Trypanosoma cruzi | 1-([2-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]methyl)-4-methylpiperazine | |
0.112 | - |
at 25°C, pH not specified in the publication | Leishmania donovani | 2-[5-[(4-methylpiperazin-1-yl)methyl]-1H-imidazol-2-yl]-N-phenyl-3-(phenylsulfanyl)aniline | |
0.115 | - |
at 25°C, pH not specified in the publication | Trypanosoma cruzi | 1-((2-(2,6-bis(phenylthio)phenyl)-1H-imidazol-5-yl)methyl)-4-methylpiperazine | |
0.162 | - |
at 25°C, pH not specified in the publication | Trypanosoma cruzi | 2-[5-[(dimethylamino)methyl]-1H-imidazol-2-yl]-N-phenyl-3-(phenylsulfanyl)aniline | |
0.18 | - |
at 25°C, pH not specified in the publication | Leishmania donovani | 2-[5-[(dimethylamino)methyl]-1H-imidazol-2-yl]-N-phenyl-3-(phenylsulfanyl)aniline | |
0.194 | - |
at 25°C, pH not specified in the publication | Leishmania donovani | 1-([2-[5-bromo-2-(phenylsulfanyl)phenyl]-1H-imidazol-5-yl]methyl)-4-methylpiperazine |