Literature summary for 2.1.1.37 extracted from

Albert, P.; Varga, B.; Zsibrita, N.; Kiss, A.
Circularly permuted variants of two CG-specific prokaryotic DNA methyltransferases (2018), PLoS ONE, 13, e0197232 .

Search for more literature for 2.1.1.37

Protein Variants

Protein Variants	Comment	Organism
additional information	creation of genes encoding circularly permuted variants of M.MpeI. Eleven of the fourteen M.MpeI permutants have detectable MTase activity. Permutant cp62M.MpeI, in which the new N-terminus is located between conserved motifs II and III, has by far the highest activity, comparable to the activity of wild-type M.MpeI. The MTase activity of the permutants measured in cell extracts is in most cases substantially lower than that of the wild-type enzyme, although permutation sites were designed to fall outside of conserved motifs	Malacoplasma penetrans
additional information	creation of genes encoding circularly permuted variants of M.SssI. Six of the seven M.SssI permutants have detectable MTase activity. Permutant cp58M.SssI, in which the new N-terminus is located between conserved motifs II and III, has by far the highest activity. The MTase activity of the permutants measured in cell extracts is in most cases substantially lower than that of the wild-type enzyme, although permutation sites were designed to fall outside of conserved motifs	Spiroplasma monobiae

Organism

Organism	UniProt	Comment	Textmining
Malacoplasma penetrans	Q8EVR5	-	-
Malacoplasma penetrans HF-2	Q8EVR5	-	-
Spiroplasma monobiae	P15840	-	-
Spiroplasma monobiae ATCC 33825	P15840	-	-

Synonyms

Synonyms	Comment	Organism
M.MpeI	-	Malacoplasma penetrans
M.SssI	-	Spiroplasma monobiae
MYPE4940	-	Malacoplasma penetrans
ssssIM	-	Spiroplasma monobiae

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Release 2023.1 (January 2023)