Literature summary for 2.3.1.180 extracted from

Choi, K.; Heath, R.; Rock, C.
beta-Ketoacyl-acyl carrier protein synthase III (FabH) is a determining factor in branched-chain fatty acid biosynthesis (2000), J. Bacteriol., 182, 365-370 .

Search for more literature for 2.3.1.180

Organism

Organism	UniProt	Comment	Textmining
Bacillus subtilis	O07600	isoform FabH2, Cf. EC 2.3.1.300	-
Bacillus subtilis	O34746	cf. EC 2.3.1.300	-
Bacillus subtilis 168	O07600	isoform FabH2, Cf. EC 2.3.1.300	-
Bacillus subtilis 168	O34746	cf. EC 2.3.1.300	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.016	-	substrate isovaleryl-CoA, pH 7, 37°C	Bacillus subtilis
0.058	-	substrate isobutanoyl-CoA, pH 7, 37°C	Bacillus subtilis

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
acetyl-CoA + malonyl-[acyl-carrier protein]	-	Bacillus subtilis	3-oxobutanoyl-[acyl-carrier protein] + CoA + CO2	-	?
acetyl-CoA + malonyl-[acyl-carrier protein]	-	Bacillus subtilis 168	3-oxobutanoyl-[acyl-carrier protein] + CoA + CO2	-	?
butanoyl-CoA + malonyl-[acyl-carrier protein]	-	Bacillus subtilis	3-oxohexanoyl-[acyl-carrier-protein] + CoA + CO2	-	?
butanoyl-CoA + malonyl-[acyl-carrier protein]	-	Bacillus subtilis 168	3-oxohexanoyl-[acyl-carrier-protein] + CoA + CO2	-	?
heptanoyl-CoA + malonyl-[acyl-carrier protein]	-	Bacillus subtilis	3-oxo-nonanoyl-[acyl-carrier protein] + CoA + CO2	-	?
heptanoyl-CoA + malonyl-[acyl-carrier protein]	-	Bacillus subtilis 168	3-oxo-nonanoyl-[acyl-carrier protein] + CoA + CO2	-	?
hexanoyl-CoA + malonyl-[acyl-carrier protein]	-	Bacillus subtilis	3-oxo-octanoyl-[acyl-carrier protein] + CoA + CO2	-	?
hexanoyl-CoA + malonyl-[acyl-carrier protein]	-	Bacillus subtilis 168	3-oxo-octanoyl-[acyl-carrier protein] + CoA + CO2	-	?
octanoyl-CoA + malonyl-[acyl-carrier protein]	-	Bacillus subtilis	3-oxodecanoyl-[acyl-carrier protein] + CoA + CO2	-	?
octanoyl-CoA + malonyl-[acyl-carrier protein]	-	Bacillus subtilis 168	3-oxodecanoyl-[acyl-carrier protein] + CoA + CO2	-	?
propanoyl-CoA + malonyl-[acyl-carrier protein]	-	Bacillus subtilis	3-oxopentanoyl-[acyl-carrier-protein] + CoA + CO2	-	?
valeryl-CoA + malonyl-[acyl-carrier protein]	-	Bacillus subtilis	3-oxoheptanoyl-[acyl-carrier-protein] + CoA + CO2	-	?

Subunits

Subunits	Comment	Organism
?	x * 39800, SDS-PAGE, His-tagged recombinant protein	Bacillus subtilis
?	x * 42700, SDS-PAGE, His-tagged recombinant protein	Bacillus subtilis

Synonyms

Synonyms	Comment	Organism
FabH1	-	Bacillus subtilis
FabH2	-	Bacillus subtilis
FabHA	-	Bacillus subtilis
FabHB	-	Bacillus subtilis

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Release 2023.1 (January 2023)